WO2001094331A8 - Methods for producing amino-substituted chromanes - Google Patents

Methods for producing amino-substituted chromanes

Info

Publication number
WO2001094331A8
WO2001094331A8 PCT/US2001/018014 US0118014W WO0194331A8 WO 2001094331 A8 WO2001094331 A8 WO 2001094331A8 US 0118014 W US0118014 W US 0118014W WO 0194331 A8 WO0194331 A8 WO 0194331A8
Authority
WO
WIPO (PCT)
Prior art keywords
methods
producing amino
producing
substituted chromanes
acetic acid
Prior art date
Application number
PCT/US2001/018014
Other languages
French (fr)
Other versions
WO2001094331A2 (en
WO2001094331A3 (en
Inventor
Luc Antoine
Pascal Boquel
Alfia Borghese
Hugo Gorissen
Michael Martinelli
Alain Merschaert
Gerd Ruhter
Carine Rypens
Robert Scarborough
Theo Schotten
Hoeck Jean-Pierre Van
Original Assignee
Lilly Co Eli
Cor Therapeutics Inc
Luc Antoine
Pascal Boquel
Alfia Borghese
Hugo Gorissen
Michael Martinelli
Alain Merschaert
Gerd Ruhter
Carine Rypens
Robert Scarborough
Theo Schotten
Hoeck Jean-Pierre Van
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli, Cor Therapeutics Inc, Luc Antoine, Pascal Boquel, Alfia Borghese, Hugo Gorissen, Michael Martinelli, Alain Merschaert, Gerd Ruhter, Carine Rypens, Robert Scarborough, Theo Schotten, Hoeck Jean-Pierre Van filed Critical Lilly Co Eli
Priority to US10/296,782 priority Critical patent/US20040014804A1/en
Priority to EP01946070A priority patent/EP1286983A2/en
Priority to AU2001268165A priority patent/AU2001268165A1/en
Publication of WO2001094331A2 publication Critical patent/WO2001094331A2/en
Publication of WO2001094331A3 publication Critical patent/WO2001094331A3/en
Publication of WO2001094331A8 publication Critical patent/WO2001094331A8/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/58—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Diabetes (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Hematology (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrane Compounds (AREA)

Abstract

Disclosed are processes for producing benzopyran compounds, reduced 2-(chroman-2-yl) acetic acid compounds and 2-(6-aminochroman-2-yl)acetic acid esters which are intermediates for producing platelet aggregation inhibitors and/or are themselves potent platelet aggregation inhibitors.
PCT/US2001/018014 2000-06-02 2001-06-01 Methods for producing amino-substituted chromanes WO2001094331A2 (en)

Priority Applications (3)

Application Number Priority Date Filing Date Title
US10/296,782 US20040014804A1 (en) 2001-06-01 2001-06-01 Methods for producing amino-substituted chromanes
EP01946070A EP1286983A2 (en) 2000-06-02 2001-06-01 Methods for producing amino-substituted chromanes
AU2001268165A AU2001268165A1 (en) 2000-06-02 2001-06-01 Methods for producing amino-substituted chromanes

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US20882600P 2000-06-02 2000-06-02
US60/208,826 2000-06-02

Publications (3)

Publication Number Publication Date
WO2001094331A2 WO2001094331A2 (en) 2001-12-13
WO2001094331A3 WO2001094331A3 (en) 2002-09-06
WO2001094331A8 true WO2001094331A8 (en) 2003-11-06

Family

ID=22776205

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2001/018014 WO2001094331A2 (en) 2000-06-02 2001-06-01 Methods for producing amino-substituted chromanes

Country Status (3)

Country Link
EP (1) EP1286983A2 (en)
AU (1) AU2001268165A1 (en)
WO (1) WO2001094331A2 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN112794818A (en) * 2019-11-13 2021-05-14 邵阳学院 Preparation method of N-propylaminoquinolinone and application of N-propylaminoquinolinone in synthesis of abscisic acid agonist AM1 and derivatives thereof

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5731324A (en) * 1993-07-22 1998-03-24 Eli Lilly And Company Glycoprotein IIb/IIIa antagonists

Also Published As

Publication number Publication date
EP1286983A2 (en) 2003-03-05
WO2001094331A2 (en) 2001-12-13
AU2001268165A1 (en) 2001-12-17
WO2001094331A3 (en) 2002-09-06

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