WO2001089548A3 - Pharmaceutical use of fibulin-1 - Google Patents

Pharmaceutical use of fibulin-1 Download PDF

Info

Publication number
WO2001089548A3
WO2001089548A3 PCT/US2001/016791 US0116791W WO0189548A3 WO 2001089548 A3 WO2001089548 A3 WO 2001089548A3 US 0116791 W US0116791 W US 0116791W WO 0189548 A3 WO0189548 A3 WO 0189548A3
Authority
WO
WIPO (PCT)
Prior art keywords
fibulin
pharmaceutical use
endometriosis
polypeptide
diagnosis
Prior art date
Application number
PCT/US2001/016791
Other languages
French (fr)
Other versions
WO2001089548A2 (en
Inventor
Holger Hess-Stump
Bernard Haendler
Bruce Lessey
Kristof Chwalisz
Original Assignee
Schering Ag
Univ North Carolina
Holger Hess-Stump
Bernard Haendler
Bruce Lessey
Kristof Chwalisz
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Ag, Univ North Carolina, Holger Hess-Stump, Bernard Haendler, Bruce Lessey, Kristof Chwalisz filed Critical Schering Ag
Priority to EP01939374A priority Critical patent/EP1301195A2/en
Priority to AU2001264900A priority patent/AU2001264900A1/en
Priority to JP2001585791A priority patent/JP2004504275A/en
Publication of WO2001089548A2 publication Critical patent/WO2001089548A2/en
Publication of WO2001089548A3 publication Critical patent/WO2001089548A3/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/78Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin, cold insoluble globulin [CIG]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/39Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin, cold insoluble globulin [CIG]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • A61P15/08Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy

Abstract

This invention relates to the pharmaceutical use of the fibulin-1 polypeptide and the fibulin-1 nucleic acid in female birth control and for the treatment and diagnosis of endometriosis.
PCT/US2001/016791 2000-05-24 2001-05-24 Pharmaceutical use of fibulin-1 WO2001089548A2 (en)

Priority Applications (3)

Application Number Priority Date Filing Date Title
EP01939374A EP1301195A2 (en) 2000-05-24 2001-05-24 Pharmaceutical use of fibulin-1
AU2001264900A AU2001264900A1 (en) 2000-05-24 2001-05-24 Pharmaceutical use of fibulin-1
JP2001585791A JP2004504275A (en) 2000-05-24 2001-05-24 Pharmaceutical uses of fibulin-1

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US57749900A 2000-05-24 2000-05-24
US09/577,499 2000-05-24

Publications (2)

Publication Number Publication Date
WO2001089548A2 WO2001089548A2 (en) 2001-11-29
WO2001089548A3 true WO2001089548A3 (en) 2003-01-23

Family

ID=24308988

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2001/016791 WO2001089548A2 (en) 2000-05-24 2001-05-24 Pharmaceutical use of fibulin-1

Country Status (4)

Country Link
EP (1) EP1301195A2 (en)
JP (1) JP2004504275A (en)
AU (1) AU2001264900A1 (en)
WO (1) WO2001089548A2 (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2009055864A1 (en) * 2007-10-31 2009-05-07 Crc For Asthma And Airways Ltd Methods and compositions for regulating airway tissue remodelling
WO2010010201A1 (en) 2008-07-22 2010-01-28 Equipo Ivi Investigacion Sl Gene expression profile as a marker of endometrial receptivity
MX2016016756A (en) 2014-06-17 2017-11-02 Igenomix S L Stem cell therapy in endometrial pathologies.
CN113621699A (en) * 2021-08-10 2021-11-09 张存泰 Fibulin-1 protein as vascular aging molecular marker and application thereof

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1991002755A1 (en) * 1989-08-18 1991-03-07 La Jolla Cancer Research Foundation Fibulin
WO1997038014A1 (en) * 1996-04-04 1997-10-16 Amgen Inc. Fibulin pharmaceutical compositions and related methods

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1991002755A1 (en) * 1989-08-18 1991-03-07 La Jolla Cancer Research Foundation Fibulin
WO1997038014A1 (en) * 1996-04-04 1997-10-16 Amgen Inc. Fibulin pharmaceutical compositions and related methods

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
ARGRAVES W S ET AL: "FIBULIN, A NOVEL PROTEIN THAT INTERACTS WITH THE FIBRONECTIN RECEPTOR BETA SUBUNIT CYTOPLASMIC DOMAIN", CELL, CELL PRESS, CAMBRIDGE, NA, US, vol. 58, 25 August 1989 (1989-08-25), pages 623 - 629, XP002036653, ISSN: 0092-8674 *

Also Published As

Publication number Publication date
WO2001089548A2 (en) 2001-11-29
AU2001264900A1 (en) 2001-12-03
JP2004504275A (en) 2004-02-12
EP1301195A2 (en) 2003-04-16

Similar Documents

Publication Publication Date Title
WO2003057134A3 (en) Specific binding agents of human angiopoietin-2
MXPA02011656A (en) Nrg 2 nucleic acid molecules, polypeptides, and diagnostic and therapeutic methods.
IL161268A0 (en) Nucleic acid and corresponding protein entitled 161p2f10b and pharmaceutical and diagnostic compositions containing the same
AU2002216273A1 (en) Proteins, genes and their use for diagnosis and treatment of kidney response
WO2002008285A3 (en) Il-17 molecules and uses thereof
WO2001049728A3 (en) HUMAN PROTEINS HAVING HYDROPHOBIC DOMAINS AND DNAs ENCODING THESE PROTEINS
IL217317A0 (en) Nucleic acid and corresponding protein entitled 161p2f10b and pharmaceutical and diagnostic compositions containing the same and uses thereof
WO2005056585A3 (en) Sars coronavirus s proteins and uses thereof
WO2000053776A3 (en) Human kallikrein-like genes
AU2002210926A1 (en) Genomes participating in rheumatoid arthritis, method of the diagnosis thereof, method of evaluating the onset possibility thereof, diagnostic kit for detecting them and therapeutic method and remedies for rheumatoid arthritis
WO2001089548A3 (en) Pharmaceutical use of fibulin-1
WO2001007479A3 (en) Fragments of cellular prion protein and methods useful in the diagnosis and treatment of prion diseases
EP2088197A3 (en) Haemophilus influenzae antigens and corresponding DNA fragments
WO2001059120A3 (en) Il-17 like molecules and uses thereof
AU2001237543A1 (en) Proteins, genes and their use for diagnosis and treatment of schizophrenia
WO2005011728A3 (en) Use of soluble cd164 in inflammatory and/or autoimmune disorders
WO2002070563A3 (en) Nuclear hormone receptor ligand binding domain
AU2001280256A1 (en) Methods for the diagnosis and/or treatment of diseases related to anti-phospholipid antibodies and devices used therein
WO2001085785A3 (en) Ph domain-interacting protein
EP1293570A3 (en) Application of aprataxin gene to diagnosis and treatment for early-onset spinocerebellar ataxia (EAOH)
EP1329504A4 (en) Nucleic acid of novel human kinesin-associated gene, protein encoded by the nucleic acid, peptide fragment thereof and anticancer agents comprising the nucleic acid and the like
AU2002364757A8 (en) Peptides for the production of preparations for the diagnosis and therapy of autoimmun diseases
AU2001244151A1 (en) Peptide and nucleic acid coding therefor for the detection, diagnosis and therapy of diseases of the nervous system
WO2002070560A3 (en) Nuclear hormone receptor ligand binding domain
AU2002222308A1 (en) Proteins, genes and their use for diagnosis and treatment of vascular response

Legal Events

Date Code Title Description
AK Designated states

Kind code of ref document: A2

Designated state(s): AE AG AL AM AT AU AZ BA BB BG BR BY BZ CA CH CN CO CR CU CZ DE DK DM DZ EE ES FI GB GD GE GH GM HR HU ID IL IN IS JP KE KG KP KR KZ LC LK LR LS LT LU LV MA MD MG MK MN MW MX MZ NO NZ PL PT RO RU SD SE SG SI SK SL TJ TM TR TT TZ UA UG US UZ VN YU ZA ZW

AL Designated countries for regional patents

Kind code of ref document: A2

Designated state(s): GH GM KE LS MW MZ SD SL SZ TZ UG ZW AM AZ BY KG KZ MD RU TJ TM AT BE CH CY DE DK ES FI FR GB GR IE IT LU MC NL PT SE TR BF BJ CF CG CI CM GA GN GW ML MR NE SN TD TG

121 Ep: the epo has been informed by wipo that ep was designated in this application
DFPE Request for preliminary examination filed prior to expiration of 19th month from priority date (pct application filed before 20040101)
WWE Wipo information: entry into national phase

Ref document number: 2001939374

Country of ref document: EP

WWP Wipo information: published in national office

Ref document number: 2001939374

Country of ref document: EP

WWW Wipo information: withdrawn in national office

Ref document number: 2001939374

Country of ref document: EP