WO2001089477A3 - Controlled release of materials from polymer matrices - Google Patents

Controlled release of materials from polymer matrices Download PDF

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Publication number
WO2001089477A3
WO2001089477A3 PCT/US2001/016251 US0116251W WO0189477A3 WO 2001089477 A3 WO2001089477 A3 WO 2001089477A3 US 0116251 W US0116251 W US 0116251W WO 0189477 A3 WO0189477 A3 WO 0189477A3
Authority
WO
WIPO (PCT)
Prior art keywords
polymer
active ingredient
materials
controlled release
polymer matrices
Prior art date
Application number
PCT/US2001/016251
Other languages
French (fr)
Other versions
WO2001089477A2 (en
Inventor
Vince Mcginniss
Siu Man L Cowan
Original Assignee
Battelle Memorial Institute
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Battelle Memorial Institute filed Critical Battelle Memorial Institute
Priority to AU2001264706A priority Critical patent/AU2001264706A1/en
Publication of WO2001089477A2 publication Critical patent/WO2001089477A2/en
Publication of WO2001089477A3 publication Critical patent/WO2001089477A3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1641—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poloxamers
    • A61K9/1647—Polyesters, e.g. poly(lactide-co-glycolide)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1635—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates

Abstract

Compositions and methods for controllably releasing a material or active ingredient from a polymer matrix. A typical controlled-release composition includes an active ingredient or ingredients; at least one polymer for capturing the active ingredient or in which the active ingredient is embedded; and a degradation controlling material for degrading or otherwise altering the polymer, whereby the active ingredient is controllably released from the polymer upon the addition of the degradation controlling material to the at least one polymer.
PCT/US2001/016251 2000-05-19 2001-05-18 Controlled release of materials from polymer matrices WO2001089477A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2001264706A AU2001264706A1 (en) 2000-05-19 2001-05-18 Controlled release of materials from polymer matrices

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US57508900A 2000-05-19 2000-05-19
US09/575,089 2000-05-19

Publications (2)

Publication Number Publication Date
WO2001089477A2 WO2001089477A2 (en) 2001-11-29
WO2001089477A3 true WO2001089477A3 (en) 2003-01-30

Family

ID=24298888

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2001/016251 WO2001089477A2 (en) 2000-05-19 2001-05-18 Controlled release of materials from polymer matrices

Country Status (2)

Country Link
AU (1) AU2001264706A1 (en)
WO (1) WO2001089477A2 (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL1028019C2 (en) * 2005-01-14 2006-07-17 Holland Novochem B V Free-flowing, mineral oil-free granulate particles of plant auxiliary agent comprises reaction product of plant auxiliary agent containing nitrogen, phosphorus and/or potassium and waste flow of natural material containing nitrogen compound
JP5051522B2 (en) * 2007-04-18 2012-10-17 株式会社森川商店 Flame retardant for thermoplastic resin and flame retardant resin composition
ES2347119B2 (en) * 2009-04-22 2011-04-28 Universidad De Santiago De Compostela POLYARGININE NANOCAPSULES.
US20110274763A1 (en) * 2009-05-19 2011-11-10 Nyden Bo Magnus Slow releasing microcapsules and microspheres containing an active substance

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS57112321A (en) * 1980-12-29 1982-07-13 Japan Atom Energy Res Inst Preparation of prolonged release composite
US4405360A (en) * 1979-06-22 1983-09-20 Environmental Chemicals, Inc. Controlled release of herbicide compounds utilizing a thermoplastic matrix
EP0486959A1 (en) * 1990-11-22 1992-05-27 Vectorpharma International S.P.A. Pharmaceutical composition of microparticles with controlled release and process of preparing it
WO1996028143A1 (en) * 1995-03-10 1996-09-19 Boehringer Mannheim Gmbh Polypeptide-containing pharmaceutical forms of administration in the form of microparticles and method for the preparation thereof
WO1998007318A2 (en) * 1996-08-19 1998-02-26 Battelle Memorial Institute Method of making controlled release devices
US5869103A (en) * 1994-06-18 1999-02-09 Danbiosyst Uk Limited Polymer microparticles for drug delivery

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4405360A (en) * 1979-06-22 1983-09-20 Environmental Chemicals, Inc. Controlled release of herbicide compounds utilizing a thermoplastic matrix
JPS57112321A (en) * 1980-12-29 1982-07-13 Japan Atom Energy Res Inst Preparation of prolonged release composite
EP0486959A1 (en) * 1990-11-22 1992-05-27 Vectorpharma International S.P.A. Pharmaceutical composition of microparticles with controlled release and process of preparing it
US5869103A (en) * 1994-06-18 1999-02-09 Danbiosyst Uk Limited Polymer microparticles for drug delivery
WO1996028143A1 (en) * 1995-03-10 1996-09-19 Boehringer Mannheim Gmbh Polypeptide-containing pharmaceutical forms of administration in the form of microparticles and method for the preparation thereof
WO1998007318A2 (en) * 1996-08-19 1998-02-26 Battelle Memorial Institute Method of making controlled release devices

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
DATABASE WPI Section Ch Week 198233, Derwent World Patents Index; Class A96, AN 1982-69441E, XP002213108 *

Also Published As

Publication number Publication date
AU2001264706A1 (en) 2001-12-03
WO2001089477A2 (en) 2001-11-29

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