WO2001083816A3 - Procedes de detection de tumeurs - Google Patents
Procedes de detection de tumeurs Download PDFInfo
- Publication number
- WO2001083816A3 WO2001083816A3 PCT/IB2001/000899 IB0100899W WO0183816A3 WO 2001083816 A3 WO2001083816 A3 WO 2001083816A3 IB 0100899 W IB0100899 W IB 0100899W WO 0183816 A3 WO0183816 A3 WO 0183816A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- tumors
- component
- detecting tumors
- sample
- tenascin
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
- C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/158—Expression markers
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Analytical Chemistry (AREA)
- Zoology (AREA)
- Genetics & Genomics (AREA)
- Wood Science & Technology (AREA)
- Physics & Mathematics (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Molecular Biology (AREA)
- Hospice & Palliative Care (AREA)
- Biophysics (AREA)
- Oncology (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Abstract
L'invention concerne la détection de tumeurs, y compris de tumeurs latentes, par analyse du liquide organique d'un individu. En particulier, l'invention concerne la détermination de la présence ou de l'absence, dans un échantillon de liquide organique, d'un ARN messager (mRNA) codant pour un constituant de matrice extracellulaire dans cet échantillon, lequel constituant est trouvé en particulier dans les tumeurs. Ce constituant peut être de la fibronectine ED-A, ED-B, ou une isoforme de grande taille de tenascine C.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
AU58679/01A AU5867901A (en) | 2000-05-04 | 2001-05-03 | Method for detecting tumors |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US20186400P | 2000-05-04 | 2000-05-04 | |
US60/201,864 | 2000-05-04 |
Publications (2)
Publication Number | Publication Date |
---|---|
WO2001083816A2 WO2001083816A2 (fr) | 2001-11-08 |
WO2001083816A3 true WO2001083816A3 (fr) | 2003-03-13 |
Family
ID=22747609
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/IB2001/000899 WO2001083816A2 (fr) | 2000-05-04 | 2001-05-03 | Procedes de detection de tumeurs |
Country Status (2)
Country | Link |
---|---|
AU (1) | AU5867901A (fr) |
WO (1) | WO2001083816A2 (fr) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US9513298B2 (en) | 2004-07-30 | 2016-12-06 | Hologic, Inc. | Methods for detecting oncofetal fibronectin |
Families Citing this family (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7927840B2 (en) | 2006-09-11 | 2011-04-19 | Gen Probe Incorporated | Method for detecting West Nile Virus nucleic acids in the 3′ non-coding region |
EP2977470B1 (fr) | 2002-10-16 | 2018-01-03 | Gen-Probe Incorporated | Compositions et procédé pour la détection du virus du nil occidental |
KR101515243B1 (ko) | 2007-04-02 | 2015-04-24 | 필로겐 에스.피.에이. | 종양 전이암의 신생혈관과 관련된 피브리노겐의 ed―a 항원 |
US10202442B2 (en) | 2007-07-25 | 2019-02-12 | Philogen S.P.A. | Antigen associated with lung cancers and lymphomas |
ES2807753T3 (es) | 2007-10-30 | 2021-02-24 | Philogen Spa | Un antígeno asociado con artritis reumatoide |
WO2010078950A2 (fr) | 2009-01-07 | 2010-07-15 | Philogen S.P.A. | Antigènes associés à l'endométriose, au rhumatisme psoriasique et au psoriasis |
ES2712997T3 (es) | 2009-08-05 | 2019-05-17 | Philogen Spa | Selección como diana de neovasculatura de médula ósea |
JP6158933B2 (ja) | 2012-10-03 | 2017-07-05 | フィロゲン エスピーエー | 炎症性腸疾患に関連する抗原 |
US20180340936A1 (en) * | 2015-11-16 | 2018-11-29 | Hefei Lifeon Pharmaceutical Co. Ltd. | Use of ed-b protein in diagnosis of tissue hyperplasia |
Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1992015602A1 (fr) * | 1991-02-28 | 1992-09-17 | Dana-Farber Cancer Institute, Inc. | Diagnostic et therapie du cancer |
US5981218A (en) * | 1995-08-09 | 1999-11-09 | Bristol-Myers Squibb Company | Isolated nucleic acid molecules useful as leukemia markers and in breast cancer prognosis and encoded polypeptides |
WO2000052204A2 (fr) * | 1999-02-22 | 2000-09-08 | Orntoft Torben F | Expression genique dans les tumeurs de la vessie |
-
2001
- 2001-05-03 WO PCT/IB2001/000899 patent/WO2001083816A2/fr active Application Filing
- 2001-05-03 AU AU58679/01A patent/AU5867901A/en not_active Abandoned
Patent Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1992015602A1 (fr) * | 1991-02-28 | 1992-09-17 | Dana-Farber Cancer Institute, Inc. | Diagnostic et therapie du cancer |
US5981218A (en) * | 1995-08-09 | 1999-11-09 | Bristol-Myers Squibb Company | Isolated nucleic acid molecules useful as leukemia markers and in breast cancer prognosis and encoded polypeptides |
WO2000052204A2 (fr) * | 1999-02-22 | 2000-09-08 | Orntoft Torben F | Expression genique dans les tumeurs de la vessie |
Non-Patent Citations (5)
Title |
---|
ALBRECHT MARTIN ET AL: "Fibronectin in human prostatic cells in vivo and in vitro: Expression, distribution, and pathological significance.", HISTOCHEMISTRY AND CELL BIOLOGY, vol. 112, no. 1, July 1999 (1999-07-01), pages 51 - 61, XP002218305, ISSN: 0948-6143 * |
MICHELL A J ET AL: "HUMAN TENASCIN-C: IDENTIFICATION OF A NOVEL TYPE III REPEAT IN ORAL CANCER AND OF NOVEL SPLICE VARIANTS IN NORMAL, MALIGNANT AND REACTIVE ORAL MUCOSAE", INTERNATIONAL JOURNAL OF CANCER, NEW YORK, NY, US, vol. 72, 1997, pages 236 - 240, XP000937664, ISSN: 0020-7136 * |
NICOLO G ET AL: "EXPRESSION OF TENASCIN AND OF THE ED-B CONTAINING ONCOFETAL FIBRONECTIN ISOFORM IN HUMAN CANCER", CELL DIFFERENTIATION AND DEVELOPMENT, vol. 32, no. 3, 1990, pages 401 - 408, XP008009720, ISSN: 0922-3371 * |
OYAMA FUMITAKA ET AL: "Coordinate oncodevelopmental modulation of alternative splicing of fibronectin pre-messenger RNA at ED-A, ED-B, and CS1 regions in human liver tumors.", CANCER RESEARCH, vol. 53, no. 9, 1993, pages 2005 - 2011, XP002218306, ISSN: 0008-5472 * |
VOLLMER G ET AL: "EXPRESSION OF TENASCIN-C BY HUMAN ENDOMETRIAL ADENOCARCINOMA AND STROMA CELLS: HETEROGENEITY OF SPLICE VARIANTS AND INDUCTION BY TGF-BETA", BIOCHEMISTRY AND CELL BIOLOGY. BIOCHIMIE ET BIOLOGIE CELLULAIRE, XX, XX, vol. 75, 1997, pages 759 - 769, XP000937670, ISSN: 0829-8211 * |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US9513298B2 (en) | 2004-07-30 | 2016-12-06 | Hologic, Inc. | Methods for detecting oncofetal fibronectin |
Also Published As
Publication number | Publication date |
---|---|
WO2001083816A2 (fr) | 2001-11-08 |
AU5867901A (en) | 2001-11-12 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
EP1700912A4 (fr) | Methode de detection d'une molecule cible au moyen d'un aptamere | |
WO2004063753A3 (fr) | Marqueur serique pour mesurer une cirrhose du foie | |
WO2005041893A3 (fr) | Detection des biomarqueurs de l'infarctus aigu du myocarde | |
WO2004099432A3 (fr) | Identification de biomarqueurs permettant de detecter la presence d'un cancer du pancreas | |
WO2006002243A3 (fr) | Procedes de profilage d'oligosaccharides pour la detection du cancer | |
WO2008041953A3 (fr) | Diagnostic et traitement de la dingue | |
WO2007064567A3 (fr) | Dispositif et procede permettant de mesurer la corrosion en temps reel | |
TW200720441A (en) | New labelling strategies for the sensitive detection of analytes | |
SG169395A1 (en) | Detection of cancer by elevated levels of bcl-2 | |
WO2002097415A3 (fr) | Instruments d'analyse, biocapteurs et methodes associees | |
WO2005113817A3 (fr) | Conjugues nanoparticules-aptameres, et leur procede d'utilisation pour detecter un analyte cible | |
WO2006020579A3 (fr) | Procede d'identification rapide de micro-organismes | |
WO2004055519A3 (fr) | Marqueurs specifiques pour le cancer du pancreas | |
AU2003238869A8 (en) | Hybrid microcantilever sensors | |
EP1383914A4 (fr) | Procede perfectionne de detection de l'atp | |
PT1776587E (pt) | Utilização de c3a e seus derivados como biomarcador para o adenoma e/ou carcinoma colorrectal; processos de diagnóstico e ensaios utilizando os mesmos | |
EP1381864A4 (fr) | Detection du candida | |
GB0603665D0 (en) | Protease detection | |
WO2006001931A3 (fr) | Prouroguanyline, analogues synthetiques ou produits de clivage proteolytiques derives de celle-ci servant d'agents therapeutiques ou diagnostiques pour des maladies impliquant une homeostasie de sel et/ou d'eau | |
WO2008060651A3 (fr) | Sparc et procédés d'utilisation de celui-ci | |
WO2006010839A3 (fr) | Procede d’amelioration de la detection des signaux de fluorescence lors d’un transfert d’energie non radiatif | |
WO2001055719A3 (fr) | Kit de diagnostic permettant de detecter des niveaux de creatine | |
WO2001083816A3 (fr) | Procedes de detection de tumeurs | |
WO2004057336A3 (fr) | Utilisation de la nicotinamide n-methyltransferase comme marqueur du cancer colorectal | |
NO20052553L (no) | Cobalaminanalyse. |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
AK | Designated states |
Kind code of ref document: A2 Designated state(s): AE AG AL AM AT AU AZ BA BB BG BR BY BZ CA CH CN CO CR CU CZ DE DK DM DZ EE ES FI GB GD GE GH GM HR HU ID IL IN IS JP KE KG KP KR KZ LC LK LR LS LT LU LV MA MD MG MK MN MW MX MZ NO NZ PL PT RO RU SD SE SG SI SK SL TJ TM TR TT TZ UA UG US UZ VN YU ZA ZW |
|
AL | Designated countries for regional patents |
Kind code of ref document: A2 Designated state(s): GH GM KE LS MW MZ SD SL SZ TZ UG ZW AM AZ BY KG KZ MD RU TJ TM AT BE CH CY DE DK ES FI FR GB GR IE IT LU MC NL PT SE TR BF BJ CF CG CI CM GA GN GW ML MR NE SN TD TG |
|
121 | Ep: the epo has been informed by wipo that ep was designated in this application | ||
DFPE | Request for preliminary examination filed prior to expiration of 19th month from priority date (pct application filed before 20040101) | ||
122 | Ep: pct application non-entry in european phase | ||
NENP | Non-entry into the national phase |
Ref country code: JP |