WO2001083552A3 - Human sez6 nucleic acids and polypeptides - Google Patents

Human sez6 nucleic acids and polypeptides Download PDF

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Publication number
WO2001083552A3
WO2001083552A3 PCT/US2001/010809 US0110809W WO0183552A3 WO 2001083552 A3 WO2001083552 A3 WO 2001083552A3 US 0110809 W US0110809 W US 0110809W WO 0183552 A3 WO0183552 A3 WO 0183552A3
Authority
WO
WIPO (PCT)
Prior art keywords
polypeptides
nucleic acids
hsez6
human sez6
present
Prior art date
Application number
PCT/US2001/010809
Other languages
French (fr)
Other versions
WO2001083552A2 (en
Inventor
Eric Wen Su
Original Assignee
Lilly Co Eli
Eric Wen Su
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli, Eric Wen Su filed Critical Lilly Co Eli
Priority to AU2001256977A priority Critical patent/AU2001256977A1/en
Priority to EP01930440A priority patent/EP1290026A2/en
Priority to US10/257,904 priority patent/US20030211991A1/en
Publication of WO2001083552A2 publication Critical patent/WO2001083552A2/en
Publication of WO2001083552A3 publication Critical patent/WO2001083552A3/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; CARE OF BIRDS, FISHES, INSECTS; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2217/00—Genetically modified animals
    • A01K2217/05—Animals comprising random inserted nucleic acids (transgenic)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Psychology (AREA)
  • Cell Biology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Cardiology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pain & Pain Management (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

The present invention relates to human SEZ6 (hSEZ6) polypeptides, and isolated nucleic acids that encode at least one hSEZ6 polypeptide. Vectors, host cells, transgenics, and chimeric mammals comprising hSEZ6 polynucleotides and/or polypeptides, as well as methods of making and using thereof, and hSEZ6 -specific antibodies are included in the present invention.
PCT/US2001/010809 2000-04-28 2001-04-17 Human sez6 nucleic acids and polypeptides WO2001083552A2 (en)

Priority Applications (3)

Application Number Priority Date Filing Date Title
AU2001256977A AU2001256977A1 (en) 2000-04-28 2001-04-17 Human sez6 nucleic acids and polypeptides
EP01930440A EP1290026A2 (en) 2000-04-28 2001-04-17 Human sez6 nucleic acids and polypeptides
US10/257,904 US20030211991A1 (en) 2001-04-17 2001-04-17 Human sez6 nucleic acids and polypeptides

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US20020000P 2000-04-28 2000-04-28
US60/200,200 2000-04-28

Publications (2)

Publication Number Publication Date
WO2001083552A2 WO2001083552A2 (en) 2001-11-08
WO2001083552A3 true WO2001083552A3 (en) 2002-05-16

Family

ID=22740721

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2001/010809 WO2001083552A2 (en) 2000-04-28 2001-04-17 Human sez6 nucleic acids and polypeptides

Country Status (3)

Country Link
EP (1) EP1290026A2 (en)
AU (1) AU2001256977A1 (en)
WO (1) WO2001083552A2 (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP6401060B2 (en) 2012-02-24 2018-10-03 アッヴィ・ステムセントルクス・エル・エル・シー Anti-SEZ6 antibody and method of use
EP3338793A1 (en) 2013-08-28 2018-06-27 AbbVie Stemcentrx LLC Novel sez6 modulators and methods of use
EP3892294A1 (en) * 2013-08-28 2021-10-13 AbbVie Stemcentrx LLC Site-specific antibody conjugation methods and compositions
JP2017514143A (en) 2014-02-21 2017-06-01 アッヴィ・ステムセントルクス・エル・エル・シー Anti-DLL3 antibodies and drug conjugates for use in melanoma

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001010902A2 (en) * 1999-08-11 2001-02-15 Curagen Corporation Nucleoc acids and secreted polypeptides encoded thereby
WO2001025268A1 (en) * 1999-10-04 2001-04-12 Schrotz King Petra Human seizure related proteins

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001010902A2 (en) * 1999-08-11 2001-02-15 Curagen Corporation Nucleoc acids and secreted polypeptides encoded thereby
WO2001025268A1 (en) * 1999-10-04 2001-04-12 Schrotz King Petra Human seizure related proteins

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
DATABASE WPI Section Ch Week 200130, Derwent World Patents Index; Class A89, AN 2001-290605, XP002185414 *
See also references of EP1290026A2 *
SHIMIZU-NISHIKAWA K ET AL: "CLONING AND CHARACTERIZATION OF SEIZURE-RELATED GENE, SEZ-6", BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, ACADEMIC PRESS INC. ORLANDO, FL, US, vol. 216, no. 1, 2 November 1995 (1995-11-02), pages 382 - 389, XP002901490, ISSN: 0006-291X *

Also Published As

Publication number Publication date
AU2001256977A1 (en) 2001-11-12
WO2001083552A2 (en) 2001-11-08
EP1290026A2 (en) 2003-03-12

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