WO2001079434A3 - Nouveau polypeptide, signal peptidase humaine 10, et polynucleotide codant pour ce polypeptide - Google Patents

Nouveau polypeptide, signal peptidase humaine 10, et polynucleotide codant pour ce polypeptide Download PDF

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Publication number
WO2001079434A3
WO2001079434A3 PCT/CN2001/000482 CN0100482W WO0179434A3 WO 2001079434 A3 WO2001079434 A3 WO 2001079434A3 CN 0100482 W CN0100482 W CN 0100482W WO 0179434 A3 WO0179434 A3 WO 0179434A3
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WO
WIPO (PCT)
Prior art keywords
polypeptide
polynucleotide encoding
signal peptidase
discloses
human signal
Prior art date
Application number
PCT/CN2001/000482
Other languages
English (en)
Chinese (zh)
Other versions
WO2001079434A2 (fr
Inventor
Yumin Mao
Yi Xie
Original Assignee
Shanghai Biowindow Gene Dev
Yumin Mao
Yi Xie
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Shanghai Biowindow Gene Dev, Yumin Mao, Yi Xie filed Critical Shanghai Biowindow Gene Dev
Priority to AU63719/01A priority Critical patent/AU6371901A/en
Publication of WO2001079434A2 publication Critical patent/WO2001079434A2/fr
Publication of WO2001079434A3 publication Critical patent/WO2001079434A3/fr

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6424—Serine endopeptidases (3.4.21)

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  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

L'invention concerne un nouveau polypeptide, une signal peptidase humaine 10, et un polynucléotide codant pour ce polypeptide ainsi qu'un procédé d'obtention de ce polypeptide par des techniques recombinantes d'ADN. L'invention concerne en outre les applications de ce polypeptide dans le traitement de maladies, notamment des tumeurs malignes, de l'hémopathie, de l'infection par VIH, de maladies immunitaires et de diverses inflammations. L'invention concerne aussi l'antagoniste agissant contre le polypeptide et son action thérapeutique ainsi que les applications de ce polynucléotide codant pour la signal peptidase humaine 10.
PCT/CN2001/000482 2000-03-28 2001-03-26 Nouveau polypeptide, signal peptidase humaine 10, et polynucleotide codant pour ce polypeptide WO2001079434A2 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU63719/01A AU6371901A (en) 2000-03-28 2001-03-26 A novel polypeptide, a human signal peptidase 10 and the polynucleotide encodingthe polypeptide

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN 00115215 CN1315564A (zh) 2000-03-28 2000-03-28 一种新的多肽——人信号肽酶10和编码这种多肽的多核苷酸

Publications (2)

Publication Number Publication Date
WO2001079434A2 WO2001079434A2 (fr) 2001-10-25
WO2001079434A3 true WO2001079434A3 (fr) 2002-03-21

Family

ID=4584683

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/CN2001/000482 WO2001079434A2 (fr) 2000-03-28 2001-03-26 Nouveau polypeptide, signal peptidase humaine 10, et polynucleotide codant pour ce polypeptide

Country Status (3)

Country Link
CN (1) CN1315564A (fr)
AU (1) AU6371901A (fr)
WO (1) WO2001079434A2 (fr)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0126782D0 (en) * 2001-11-07 2002-01-02 Medical Res Council Assay

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5985638A (en) * 1997-03-26 1999-11-16 Incyte Pharmaceuticals, Inc. Microsomal signal peptidase subunit

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5985638A (en) * 1997-03-26 1999-11-16 Incyte Pharmaceuticals, Inc. Microsomal signal peptidase subunit

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
DATABASE GENBANK [online] 7 February 2000 (2000-02-07), MUNOZ-SANJUAN I. ET AL., Database accession no. (AF199606) *
KALIES K.U. ET AL., J. BIOL. CHEM., vol. 271, no. 7, 16 February 1996 (1996-02-16), pages 3925 - 3929 *

Also Published As

Publication number Publication date
WO2001079434A2 (fr) 2001-10-25
CN1315564A (zh) 2001-10-03
AU6371901A (en) 2001-10-30

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