WO2001079434A3 - A novel polypeptide, a human signal peptidase 10 and the polynucleotide encoding the polypeptide - Google Patents

A novel polypeptide, a human signal peptidase 10 and the polynucleotide encoding the polypeptide Download PDF

Info

Publication number
WO2001079434A3
WO2001079434A3 PCT/CN2001/000482 CN0100482W WO0179434A3 WO 2001079434 A3 WO2001079434 A3 WO 2001079434A3 CN 0100482 W CN0100482 W CN 0100482W WO 0179434 A3 WO0179434 A3 WO 0179434A3
Authority
WO
WIPO (PCT)
Prior art keywords
polypeptide
polynucleotide encoding
signal peptidase
discloses
human signal
Prior art date
Application number
PCT/CN2001/000482
Other languages
French (fr)
Chinese (zh)
Other versions
WO2001079434A2 (en
Inventor
Yumin Mao
Yi Xie
Original Assignee
Shanghai Biowindow Gene Dev
Yumin Mao
Yi Xie
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Shanghai Biowindow Gene Dev, Yumin Mao, Yi Xie filed Critical Shanghai Biowindow Gene Dev
Priority to AU63719/01A priority Critical patent/AU6371901A/en
Publication of WO2001079434A2 publication Critical patent/WO2001079434A2/en
Publication of WO2001079434A3 publication Critical patent/WO2001079434A3/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6424—Serine endopeptidases (3.4.21)

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)

Abstract

The present invention discloses a novel polypeptide, a human signal peptidase 10, the polynucleotide encoding the polypeptide and the method for producing the polypeptide by DNA recombinant technology. The invention also discloses the uses of the polypeptide in methods for treating various diseases, such as malignant tumour, hemopathy, HIV infection, immunological disease and various inflammation, etc. The invention also discloses the agonists againstthe polypeptide and the therapeutic action thereof. The inventionalso discloses the uses of the polynucleotide encoding the novel human signal peptidase 10.
PCT/CN2001/000482 2000-03-28 2001-03-26 A novel polypeptide, a human signal peptidase 10 and the polynucleotide encoding the polypeptide WO2001079434A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU63719/01A AU6371901A (en) 2000-03-28 2001-03-26 A novel polypeptide, a human signal peptidase 10 and the polynucleotide encodingthe polypeptide

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN 00115215 CN1315564A (en) 2000-03-28 2000-03-28 Polypeptide-human signal peptidase 10 and polynucleotide for coding it

Publications (2)

Publication Number Publication Date
WO2001079434A2 WO2001079434A2 (en) 2001-10-25
WO2001079434A3 true WO2001079434A3 (en) 2002-03-21

Family

ID=4584683

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/CN2001/000482 WO2001079434A2 (en) 2000-03-28 2001-03-26 A novel polypeptide, a human signal peptidase 10 and the polynucleotide encoding the polypeptide

Country Status (3)

Country Link
CN (1) CN1315564A (en)
AU (1) AU6371901A (en)
WO (1) WO2001079434A2 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0126782D0 (en) * 2001-11-07 2002-01-02 Medical Res Council Assay

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5985638A (en) * 1997-03-26 1999-11-16 Incyte Pharmaceuticals, Inc. Microsomal signal peptidase subunit

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5985638A (en) * 1997-03-26 1999-11-16 Incyte Pharmaceuticals, Inc. Microsomal signal peptidase subunit

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
DATABASE GENBANK [online] 7 February 2000 (2000-02-07), MUNOZ-SANJUAN I. ET AL., Database accession no. (AF199606) *
KALIES K.U. ET AL., J. BIOL. CHEM., vol. 271, no. 7, 16 February 1996 (1996-02-16), pages 3925 - 3929 *

Also Published As

Publication number Publication date
CN1315564A (en) 2001-10-03
WO2001079434A2 (en) 2001-10-25
AU6371901A (en) 2001-10-30

Similar Documents

Publication Publication Date Title
WO2001079434A3 (en) A novel polypeptide, a human signal peptidase 10 and the polynucleotide encoding the polypeptide
WO2001088084A3 (en) A novel polypeptide, a superoxide dismutase 11 and the polynucleotide encoding the polypeptide
WO2001075036A3 (en) A novel polypeptide, human immunophiline 14 and the polynucleotide encoding the polypeptide
WO2001075016A3 (en) A novel polypeptide, a human tyrosinase 16, and the polynucleotide encoding the polypeptide
WO2002000821A3 (en) A novel polypeptide, a human protein plp39 and the polynucleotide encoding the polypeptide
WO2001077287A3 (en) A novel polypeptide, human uterine globine 11 and the polynucleotide encoding the polypeptide
WO2001075024A3 (en) A novel polypeptide, nf-e2-associated human factor 13 and the polynucleotide encoding the polypeptide
WO2001075007A3 (en) A novel polypeptide, a tyrosinase 15 and the polynucleotide encoding the polypeptide
WO2001075061A3 (en) A novel polypeptide, cdv-1-42 and the polynucleotide encoding the polypeptide
WO2001075048A3 (en) A novel polypeptide, human ribosomal protein s11 23 and the polynucleotide encoding the polypeptide
WO2001075011A3 (en) A novel polypeptide, cytochrome human constitution protein 10 and the polynucleotide encoding the polypeptide
WO2001075053A3 (en) A novel polypeptide, human chaperonine 14 and the polynucleotide encoding the polypeptide
WO2001081538A3 (en) A novel polypeptide, a human connexin 9 and the polynucleotide encoding the polypeptide
WO2001083682A3 (en) A novel polypeptide, a human pax protein 11.6 and the polynucleotide encoding the polypeptide
WO2001075039A3 (en) A novel polypeptide, human rna helicase 10 and the polynucleotide encoding the polypeptide
WO2001075060A3 (en) A novel polypeptide, human cystein protease 9 and the polynucleotide encoding the polypeptide
WO2001083681A3 (en) A novel polypeptide, a human dihydroorotase 21 and the polynucleotide encoding the polypeptide
WO2002000828A3 (en) A novel polypeptide, a zinc-finger protein 34 and the polynucleotide encoding the polypeptide
WO2001075042A3 (en) A novel polypeptide, atp-dependent human hydrolase serine 9 and the polynucleotide encoding the polypeptide
WO2001083675A3 (en) A novel polypeptide, a atp-dependent human hydrolase serine 10.2 and the polynucleotide encoding the polypeptide
WO2001075058A3 (en) A NOVEL POLYPEPTIDE, HUMAN AMINOACYL-tRNA SYNTHETASE 15 TYPE II AND THE POLYNUCLEOTIDE ENCODING THE POLYPEPTIDE
WO2001077285A3 (en) A novel polypeptide, protein 13 of the amidase families and the polynucleotide encoding the polypeptide
WO2001083685A3 (en) A novel polypeptide, a cap protein 10 and the polynucleotide encoding the polypeptide
WO2001094540A3 (en) A novel polypeptide, a human glucosyl hydrolase 23 and the polynucleotide encoding the polypeptide
WO2001075056A3 (en) A novel polypeptide, human light-chain clathrine 20 and the polynucleotide encoding the polypeptide

Legal Events

Date Code Title Description
AK Designated states

Kind code of ref document: A2

Designated state(s): AE AG AL AM AT AU AZ BA BB BG BR BY BZ CA CH CO CR CU CZ DE DK DM DZ EE ES FI GB GD GE GH GM HR HU ID IL IN IS JP KE KG KP KR KZ LC LK LR LS LT LU LV MA MD MG MK MN MW MX MZ NO NZ PL PT RO RU SD SE SG SI SK SL TJ TM TR TT TZ UA UG US UZ VN YU ZA ZW

AL Designated countries for regional patents

Kind code of ref document: A2

Designated state(s): GH GM KE LS MW MZ SD SL SZ TZ UG ZW AM AZ BY KG KZ MD RU TJ TM AT BE CH CY DE DK ES FI FR GB GR IE IT LU MC NL PT SE TR BF BJ CF CG CI CM GA GN GW ML MR NE SN TD TG

121 Ep: the epo has been informed by wipo that ep was designated in this application
AK Designated states

Kind code of ref document: A3

Designated state(s): AE AG AL AM AT AU AZ BA BB BG BR BY BZ CA CH CO CR CU CZ DE DK DM DZ EE ES FI GB GD GE GH GM HR HU ID IL IN IS JP KE KG KP KR KZ LC LK LR LS LT LU LV MA MD MG MK MN MW MX MZ NO NZ PL PT RO RU SD SE SG SI SK SL TJ TM TR TT TZ UA UG US UZ VN YU ZA ZW

AL Designated countries for regional patents

Kind code of ref document: A3

Designated state(s): GH GM KE LS MW MZ SD SL SZ TZ UG ZW AM AZ BY KG KZ MD RU TJ TM AT BE CH CY DE DK ES FI FR GB GR IE IT LU MC NL PT SE TR BF BJ CF CG CI CM GA GN GW ML MR NE SN TD TG

REG Reference to national code

Ref country code: DE

Ref legal event code: 8642

122 Ep: pct application non-entry in european phase
NENP Non-entry into the national phase

Ref country code: JP