WO2001077338A3 - Nouvelles proteine kinases humaines et nouvelles enzymes de type proteine kinase - Google Patents

Nouvelles proteine kinases humaines et nouvelles enzymes de type proteine kinase Download PDF

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Publication number
WO2001077338A3
WO2001077338A3 PCT/US2001/011675 US0111675W WO0177338A3 WO 2001077338 A3 WO2001077338 A3 WO 2001077338A3 US 0111675 W US0111675 W US 0111675W WO 0177338 A3 WO0177338 A3 WO 0177338A3
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WIPO (PCT)
Prior art keywords
kinase
enzymes
protein
human
kinases
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Application number
PCT/US2001/011675
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English (en)
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WO2001077338A2 (fr
Inventor
Gregory Plowman
David Whyte
Gerard Manning
Sucha Sudarsanam
Ricardo Martinez
Sean Caenepeel
Original Assignee
Sugen Inc
Gregory Plowman
David Whyte
Gerard Manning
Sucha Sudarsanam
Ricardo Martinez
Sean Caenepeel
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sugen Inc, Gregory Plowman, David Whyte, Gerard Manning, Sucha Sudarsanam, Ricardo Martinez, Sean Caenepeel filed Critical Sugen Inc
Priority to AU2001251510A priority Critical patent/AU2001251510A1/en
Priority to EP01924901A priority patent/EP1278859A2/fr
Priority to JP2001575192A priority patent/JP2003530110A/ja
Priority to CA002404971A priority patent/CA2404971A1/fr
Priority to US10/240,315 priority patent/US20030224378A1/en
Publication of WO2001077338A2 publication Critical patent/WO2001077338A2/fr
Publication of WO2001077338A3 publication Critical patent/WO2001077338A3/fr
Priority to HK03105040.6A priority patent/HK1052726A1/zh
Priority to US11/367,775 priority patent/US20060204994A1/en

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/12—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
    • C12N9/1205—Phosphotransferases with an alcohol group as acceptor (2.7.1), e.g. protein kinases
    • A—HUMAN NECESSITIES
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  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
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Abstract

L'invention porte sur des polypeptides kinases, des séquences nucléotidiques codant pour ces polypeptides kinases, et sur différents produits et procédés utiles pour le diagnostic et le traitement de différentes maladies et états liés aux kinases. En recourant à la bioinformatique, on a pu identifier des PTK et STK de mammifères et en prédire la structure protéique.
PCT/US2001/011675 2000-04-10 2001-04-10 Nouvelles proteine kinases humaines et nouvelles enzymes de type proteine kinase WO2001077338A2 (fr)

Priority Applications (7)

Application Number Priority Date Filing Date Title
AU2001251510A AU2001251510A1 (en) 2000-04-10 2001-04-10 Human protein kinases and protein kinase-like enzymes
EP01924901A EP1278859A2 (fr) 2000-04-10 2001-04-10 Nouvelles proteine kinases humaines et nouvelles enzymes de type proteine kinase
JP2001575192A JP2003530110A (ja) 2000-04-10 2001-04-10 新規ヒト蛋白質キナーゼおよび蛋白質キナーゼ様酵素
CA002404971A CA2404971A1 (fr) 2000-04-10 2001-04-10 Nouvelles proteine kinases humaines et nouvelles enzymes de type proteine kinase
US10/240,315 US20030224378A1 (en) 2001-04-10 2001-04-10 Novel human protein kinases and protein kinase-like enzymes
HK03105040.6A HK1052726A1 (zh) 2000-04-10 2003-07-11 人類蛋白激酶及類似蛋白激酶的酵素
US11/367,775 US20060204994A1 (en) 2000-04-10 2006-03-06 Novel human protein kinases and protein kinase-like enzymes

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US19595300P 2000-04-10 2000-04-10
US60/195,953 2000-04-10
US20101500P 2000-05-01 2000-05-01
US60/201,015 2000-05-01
US21380500P 2000-06-22 2000-06-22
US60/213,805 2000-06-22

Related Child Applications (1)

Application Number Title Priority Date Filing Date
US11/367,775 Division US20060204994A1 (en) 2000-04-10 2006-03-06 Novel human protein kinases and protein kinase-like enzymes

Publications (2)

Publication Number Publication Date
WO2001077338A2 WO2001077338A2 (fr) 2001-10-18
WO2001077338A3 true WO2001077338A3 (fr) 2002-08-29

Family

ID=27393539

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2001/011675 WO2001077338A2 (fr) 2000-04-10 2001-04-10 Nouvelles proteine kinases humaines et nouvelles enzymes de type proteine kinase

Country Status (6)

Country Link
EP (1) EP1278859A2 (fr)
JP (1) JP2003530110A (fr)
AU (1) AU2001251510A1 (fr)
CA (1) CA2404971A1 (fr)
HK (1) HK1052726A1 (fr)
WO (1) WO2001077338A2 (fr)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030083284A1 (en) * 2001-08-01 2003-05-01 Isis Pharmaceuticals Inc. Antisense modulation of p70 S6 kinase expression
CA2441700A1 (fr) * 2001-03-22 2002-10-03 Genentech, Inc. Polypeptides et acides nucleiques pour bolekine
WO2003064639A1 (fr) * 2002-02-01 2003-08-07 Bayer Healthcare Ag Régulation du domaine catalytique humain de la protéine mekk
WO2004099408A1 (fr) * 2003-05-09 2004-11-18 Research Association For Biotechnology Nouvelle proteine et adn la codant
AU2004288222A1 (en) 2003-11-04 2005-05-19 Metabolex, Inc. Compositions and methods of using apoptosis signaling kinase related kinase (ASKRK)
WO2005083067A1 (fr) * 2004-02-26 2005-09-09 Bayer Healthcare Ag Nouvelle protéine kinase activée par les mitogènes, map3kx, et ses utilisations
JPWO2006054770A1 (ja) * 2004-11-22 2008-06-05 国立大学法人 東京大学 新規ｍａｐキナーゼキナーゼキナーゼ（ｍａｐｋｋｋ）
CN113740539B (zh) * 2021-08-11 2023-07-25 中元汇吉生物技术股份有限公司 一种测定特异性生长因子的试剂盒

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999015635A1 (fr) * 1997-09-19 1999-04-01 Zeneca Limited Serine/threonine kinase humaine de type ste20 activee par un stress
WO1999047686A2 (fr) * 1998-03-16 1999-09-23 Cadus Pharmaceutical Corporation Proteines humaines mekk, molecules d'acides nucleiques et procedes d'utilisation correspondants

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5736381A (en) * 1995-05-19 1998-04-07 Davis; Roger J. Cytokine-, stress-, and oncoprotein-activated human protein kinase kinases
JP2005512501A (ja) * 2000-12-06 2005-05-12 インサイト・ゲノミックス・インコーポレイテッド キナーゼおよびホスファターゼ

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999015635A1 (fr) * 1997-09-19 1999-04-01 Zeneca Limited Serine/threonine kinase humaine de type ste20 activee par un stress
WO1999047686A2 (fr) * 1998-03-16 1999-09-23 Cadus Pharmaceutical Corporation Proteines humaines mekk, molecules d'acides nucleiques et procedes d'utilisation correspondants

Non-Patent Citations (5)

* Cited by examiner, † Cited by third party
Title
DATABASE EM_HTG EMBL Heidelberg, Germany; 15 March 2000 (2000-03-15), WATERSTON R H: "The sequence of Homo sapiens clone", XP002182276 *
GROVE J R ET AL: "CLONING AND EXPRESSION OF TWO HUMAN P70 S6 KINASE POLYPEPTIDES DIFFERING ONLY AT THEIR AMINO TERMINI", MOLECULAR AND CELLULAR BIOLOGY, WASHINGTON, DC, US, vol. 11, no. 11, 1 November 1991 (1991-11-01), pages 5541 - 5550, XP002051876, ISSN: 0270-7306 *
ICHIJO H ET AL: "INDUCTION OF APOPTOSIS BY ASK1, A MAMMALIAN MAPKKK THAT ACTIVATES SAPK/JNK AND P38 SIGNALING PATHWAYS", SCIENCE, AMERICAN ASSOCIATION FOR THE ADVANCEMENT OF SCIENCE, US, vol. 275, no. 5296, 1997, pages 90 - 94, XP000933551, ISSN: 0036-8075 *
See also references of EP1278859A2 *
WANG XUHONG SUNNY ET AL: "Molecular cloning and characterization of a novel protein kinase with a catalytic domain homologous to mitogen-activated protein kinase kinase kinase.", JOURNAL OF BIOLOGICAL CHEMISTRY, vol. 271, no. 49, 1996, pages 31607 - 31611, XP002182275, ISSN: 0021-9258 *

Also Published As

Publication number Publication date
JP2003530110A (ja) 2003-10-14
AU2001251510A1 (en) 2001-10-23
WO2001077338A2 (fr) 2001-10-18
CA2404971A1 (fr) 2001-10-18
HK1052726A1 (zh) 2003-09-26
EP1278859A2 (fr) 2003-01-29

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