WO2001074995A3 - A novel polypeptide - human ataxia-telangiectasia mutant protein 15 and a polynucleotide encoding the same - Google Patents
A novel polypeptide - human ataxia-telangiectasia mutant protein 15 and a polynucleotide encoding the same Download PDFInfo
- Publication number
- WO2001074995A3 WO2001074995A3 PCT/CN2001/000230 CN0100230W WO0174995A3 WO 2001074995 A3 WO2001074995 A3 WO 2001074995A3 CN 0100230 W CN0100230 W CN 0100230W WO 0174995 A3 WO0174995 A3 WO 0174995A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- polynucleotide encoding
- same
- mutant protein
- polypeptide
- telangiectasia
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
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- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Gastroenterology & Hepatology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Zoology (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Toxicology (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
The present invention discloses a novel polypeptide - human ataxia-telangiectasia mutant protein 15 and a polynucleotide encoding the same, as well as a method of producing the polypeptide by DNArecombinant technique. The present invention also discloses methods of using the polypeptide in treatment of various disease, suchas ataxia-telangiectasia, breast cancer, various tumour, disturbance of embryo development, disorder of growth and development, immunological disease, inflammation, blood disease, HIV infection and so on. The present invention also discloses an antagonist against the polypeptide and the therapeutic use of the same. Also disclosed is the use of such novel polynucleotide encoding human ataxia-telangiectasia mutant protein 15.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| AU89277/01A AU8927701A (en) | 2000-03-02 | 2001-02-26 | A novel polypeptide, human mutation protein 15 of the telangiectasy ataxia and the polynucleotide encoding the polypeptide |
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN00111825.0 | 2000-03-02 | ||
| CN 00111825 CN1311219A (en) | 2000-03-02 | 2000-03-02 | New polypeptide-human ataxia-telangiectasis mutation protein 15 and polynucleotide for coding said polypeptide |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| WO2001074995A2 WO2001074995A2 (en) | 2001-10-11 |
| WO2001074995A3 true WO2001074995A3 (en) | 2002-06-06 |
Family
ID=4581721
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PCT/CN2001/000230 WO2001074995A2 (en) | 2000-03-02 | 2001-02-26 | A novel polypeptide - human ataxia-telangiectasia mutant protein 15 and a polynucleotide encoding the same |
Country Status (3)
| Country | Link |
|---|---|
| CN (1) | CN1311219A (en) |
| AU (1) | AU8927701A (en) |
| WO (1) | WO2001074995A2 (en) |
-
2000
- 2000-03-02 CN CN 00111825 patent/CN1311219A/en active Pending
-
2001
- 2001-02-26 AU AU89277/01A patent/AU8927701A/en not_active Abandoned
- 2001-02-26 WO PCT/CN2001/000230 patent/WO2001074995A2/en active Application Filing
Non-Patent Citations (4)
| Title |
|---|
| CLIN. GENET., vol. 55, no. 5, 1999, pages 289 - 304 * |
| HUM. MUTAT., vol. 10, no. 2, 1997, pages 100 - 107 * |
| INT. J. BIOCHEM. CELL. BIOL., vol. 31, no. 7, 1999, pages 735 - 740 * |
| J. CLIN. IMMUNOL., vol. 16, no. 5, 1996, pages 254 - 260 * |
Also Published As
| Publication number | Publication date |
|---|---|
| AU8927701A (en) | 2001-10-15 |
| CN1311219A (en) | 2001-09-05 |
| WO2001074995A2 (en) | 2001-10-11 |
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