WO2001070986A3 - Helical protein zalpha51 - Google Patents

Helical protein zalpha51 Download PDF

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Publication number
WO2001070986A3
WO2001070986A3 PCT/US2001/008493 US0108493W WO0170986A3 WO 2001070986 A3 WO2001070986 A3 WO 2001070986A3 US 0108493 W US0108493 W US 0108493W WO 0170986 A3 WO0170986 A3 WO 0170986A3
Authority
WO
WIPO (PCT)
Prior art keywords
polypeptides
zalpha51
seq
helical protein
diagnostic
Prior art date
Application number
PCT/US2001/008493
Other languages
French (fr)
Other versions
WO2001070986A2 (en
Inventor
Darrell C Conklin
Scott R Presnell
Original Assignee
Zymogenetics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Zymogenetics Inc filed Critical Zymogenetics Inc
Priority to AU2001243693A priority Critical patent/AU2001243693A1/en
Priority to CA002402757A priority patent/CA2402757A1/en
Priority to EP01916704A priority patent/EP1268804A2/en
Publication of WO2001070986A2 publication Critical patent/WO2001070986A2/en
Publication of WO2001070986A3 publication Critical patent/WO2001070986A3/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/54—Interleukins [IL]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2217/00—Genetically modified animals
    • A01K2217/05—Animals comprising random inserted nucleic acids (transgenic)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2799/00—Uses of viruses
    • C12N2799/02—Uses of viruses as vector
    • C12N2799/021—Uses of viruses as vector for the expression of a heterologous nucleic acid
    • C12N2799/026—Uses of viruses as vector for the expression of a heterologous nucleic acid where the vector is derived from a baculovirus

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

Novel four-helix bundle polypeptides, materials and methods for making them, and method of use are disclosed. The polypeptides comprise at least nine contiguous amino acid residues of SEQ ID NO:2 and SEQ ID NO:5, and may be prepared as polypeptide fusions comprise heterologous sequences, such as affinity tags. The polypeptides and polynucleotides encoding them may be used within a variety of therapeutic, diagnostic, and research applications.
PCT/US2001/008493 2000-03-17 2001-03-16 Helical protein zalpha51 WO2001070986A2 (en)

Priority Applications (3)

Application Number Priority Date Filing Date Title
AU2001243693A AU2001243693A1 (en) 2000-03-17 2001-03-16 Helical protein zalpha51
CA002402757A CA2402757A1 (en) 2000-03-17 2001-03-16 Helical protein zalpha51
EP01916704A EP1268804A2 (en) 2000-03-17 2001-03-16 Helical protein zalpha51

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US52784300A 2000-03-17 2000-03-17
US09/527,843 2000-03-17
US55845900A 2000-04-25 2000-04-25
US09/558,459 2000-04-25

Publications (2)

Publication Number Publication Date
WO2001070986A2 WO2001070986A2 (en) 2001-09-27
WO2001070986A3 true WO2001070986A3 (en) 2002-03-14

Family

ID=27062529

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2001/008493 WO2001070986A2 (en) 2000-03-17 2001-03-16 Helical protein zalpha51

Country Status (4)

Country Link
EP (1) EP1268804A2 (en)
AU (1) AU2001243693A1 (en)
CA (1) CA2402757A1 (en)
WO (1) WO2001070986A2 (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7148330B2 (en) 1999-07-30 2006-12-12 Schering Corporation Binding compounds for IL-27
AU2001297949A1 (en) * 2000-11-17 2002-10-15 Zymogenetics, Inc. Mammalian alpha-helical protein-53
WO2005044850A1 (en) * 2003-10-29 2005-05-19 Zymogenetics, Inc. Helical protein zcyto32

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999029720A2 (en) * 1997-12-10 1999-06-17 Zymogenetics, Inc. Mammalian alpha helical protein-1
WO2001009176A2 (en) * 1999-07-30 2001-02-08 Schering Corporation Mammalian cytokines; related reagents

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999029720A2 (en) * 1997-12-10 1999-06-17 Zymogenetics, Inc. Mammalian alpha helical protein-1
WO2001009176A2 (en) * 1999-07-30 2001-02-08 Schering Corporation Mammalian cytokines; related reagents

Non-Patent Citations (6)

* Cited by examiner, † Cited by third party
Title
B.J. LOFTUS ET AL: "Genome duplications and other features in 12Mbof DNA sequence from human chromosome 16p and 16q", GENOMICS, vol. 60, no. 3, 1999, pages 295 - 308, XP004444802, DOI: doi:10.1006/geno.1999.5927 *
C.W. ARENDT ET AL: "Alternative splicing of transcripts encoding the alpha- and beta-subunits of mouse glucosidase in T lymphocytes", GLYCOBIOLOGY, vol. 9, 1999, pages 277 - 283, XP002179206 *
DATABASE EMBL 13 July 1999 (1999-07-13), C.W. ARENDT ET AL: "Mus musculus glucosidase II beta-subunit gene, alternative spliced products, partial cds", XP002178961 *
DATABASE EMBL 18 August 1998 (1998-08-18), NCI-CGAP: "ow88d07.s1 Soares_fetal_liver spleen_1NFLS_S1 Homo sapiens cDNA clone IMAGE: 1653901 3' similar to contains element MER22 repetitive element", XP002165908 *
DATABASE EMBL 23 September 1997 (1997-09-23), LOFTUS ET AL: "Homo sapiens chromosome 16 BAC clone CIT987SK-A-761H5,complete sequence", XP002178962 *
UNPUBLISHED *

Also Published As

Publication number Publication date
WO2001070986A2 (en) 2001-09-27
EP1268804A2 (en) 2003-01-02
AU2001243693A1 (en) 2001-10-03
CA2402757A1 (en) 2001-09-27

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