WO2001070807A3 - G-protein associated molecules - Google Patents

G-protein associated molecules Download PDF

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Publication number
WO2001070807A3
WO2001070807A3 PCT/US2001/009220 US0109220W WO0170807A3 WO 2001070807 A3 WO2001070807 A3 WO 2001070807A3 US 0109220 W US0109220 W US 0109220W WO 0170807 A3 WO0170807 A3 WO 0170807A3
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WIPO (PCT)
Prior art keywords
gpam
protein associated
associated molecules
provides
polynucleotides
Prior art date
Application number
PCT/US2001/009220
Other languages
French (fr)
Other versions
WO2001070807A2 (en
Inventor
Preeti Lal
Henry Yue
Dyung Aina M Lu
Original Assignee
Incyte Genomics Inc
Preeti Lal
Henry Yue
Dyung Aina M Lu
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Incyte Genomics Inc, Preeti Lal, Henry Yue, Dyung Aina M Lu filed Critical Incyte Genomics Inc
Priority to AU2001245943A priority Critical patent/AU2001245943A1/en
Priority to US10/239,704 priority patent/US20030208040A1/en
Priority to EP01918926A priority patent/EP1265919A2/en
Priority to JP2001569007A priority patent/JP2004501610A/en
Priority to CA002402747A priority patent/CA2402747A1/en
Publication of WO2001070807A2 publication Critical patent/WO2001070807A2/en
Publication of WO2001070807A3 publication Critical patent/WO2001070807A3/en

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    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
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Abstract

The invention provides human G-protein associated molecules (GPAM) and polynucleotides which identify and encode GPAM. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating, or preventing disorders associated with aberrant expression of GPAM.
PCT/US2001/009220 2000-03-23 2001-03-22 G-protein associated molecules WO2001070807A2 (en)

Priority Applications (5)

Application Number Priority Date Filing Date Title
AU2001245943A AU2001245943A1 (en) 2000-03-23 2001-03-22 G-protein associated molecules
US10/239,704 US20030208040A1 (en) 2001-03-22 2001-03-22 G-protein associated molecules
EP01918926A EP1265919A2 (en) 2000-03-23 2001-03-22 G-protein associated molecules
JP2001569007A JP2004501610A (en) 2000-03-23 2001-03-22 G protein-related molecules
CA002402747A CA2402747A1 (en) 2000-03-23 2001-03-22 G-protein associated molecules

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US19163100P 2000-03-23 2000-03-23
US60/191,631 2000-03-23

Publications (2)

Publication Number Publication Date
WO2001070807A2 WO2001070807A2 (en) 2001-09-27
WO2001070807A3 true WO2001070807A3 (en) 2002-02-21

Family

ID=22706253

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2001/009220 WO2001070807A2 (en) 2000-03-23 2001-03-22 G-protein associated molecules

Country Status (5)

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EP (1) EP1265919A2 (en)
JP (1) JP2004501610A (en)
AU (1) AU2001245943A1 (en)
CA (1) CA2402747A1 (en)
WO (1) WO2001070807A2 (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6774223B2 (en) * 2000-06-28 2004-08-10 Diadexus, Inc. Method of diagnosing, monitoring, staging, imaging and treating colon cancer
JP2004518413A (en) * 2000-10-12 2004-06-24 エクセリクシス・インコーポレイテッド Human ECT2 and usage

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1998037196A1 (en) * 1997-02-25 1998-08-27 Ludwig Institute For Cancer Research PARG, A GTPase ACTIVATING PROTEIN WHICH INTERACTS WITH PTPL1
WO1998057990A2 (en) * 1997-06-17 1998-12-23 Onyx Pharmaceuticals, Inc. Methods and compositions for treating abnormal cell growth related to unwanted guanine nucleotide exchange factor activity
EP1074617A2 (en) * 1999-07-29 2001-02-07 Helix Research Institute Primers for synthesising full-length cDNA and their use

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1998037196A1 (en) * 1997-02-25 1998-08-27 Ludwig Institute For Cancer Research PARG, A GTPase ACTIVATING PROTEIN WHICH INTERACTS WITH PTPL1
WO1998057990A2 (en) * 1997-06-17 1998-12-23 Onyx Pharmaceuticals, Inc. Methods and compositions for treating abnormal cell growth related to unwanted guanine nucleotide exchange factor activity
EP1074617A2 (en) * 1999-07-29 2001-02-07 Helix Research Institute Primers for synthesising full-length cDNA and their use

Non-Patent Citations (12)

* Cited by examiner, † Cited by third party
Title
DATABASE EMBL [online] 1 March 2001 (2001-03-01), XP002178396, Database accession no. Q9H8V3 *
DATABASE EMBL [online] 1 October 2000 (2000-10-01), XP002178398, Database accession no. Q9NSV8 *
DATABASE EMBL [online] 1 October 2000 (2000-10-01), XP002178399, Database accession no. Q9NV62 *
DATABASE EMBL [online] 13 May 1997 (1997-05-13), XP002178392, Database accession no. AA416834 *
DATABASE EMBL [online] 14 June 2001 (2001-06-14), XP002178400, Database accession no. BAB55317 *
DATABASE EMBL [online] 15 July 1999 (1999-07-15), XP002178395, Database accession no. Q07139 *
DATABASE EMBL [online] 22 February 2000 (2000-02-22), XP002178393, Database accession no. AK001323 *
DATABASE EMBL [online] 22 February 2000 (2000-02-22), XP002178394, Database accession no. AK001766 *
DATABASE EMBL [Online] 26 June 2001 (2001-06-26) Database accession nos: AAH04036;AH07007;AAH08590;AAH14169; AAB92847;AAH14386;AAH14655;AAB93279; AAH14693;AAB93316;AAH15428;AAB93830; AAH16330;AAB94519;AAH16753;AAB94812. *
DATABASE EMBL [online] 30 July 1999 (1999-07-30), XP002178391, Database accession no. AI916675 *
OVERBECK A F ET AL: "GUANINE NUCLEOTIDE EXCHANGE FACTORS: ACTIVATORS OF RAS SUPERFAMILY PROTEINS", MOLECULAR REPRODUCTION AND DEVELOPMENT, NEW YORK, NY, US, vol. 42, 1995, pages 468 - 476, XP000910820 *
SASAKI TAKUYA ET AL: "The rho small G protein family-Rho GDI system as a temporal and spatial determinant for cytoskeletal control.", BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, vol. 245, no. 3, 28 April 1998 (1998-04-28), pages 641 - 645, XP002178390, ISSN: 0006-291X *

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CA2402747A1 (en) 2001-09-27
WO2001070807A2 (en) 2001-09-27
AU2001245943A1 (en) 2001-10-03
EP1265919A2 (en) 2002-12-18
JP2004501610A (en) 2004-01-22

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