WO2001068830A8 - Ifi206, a novel interferon-induced polypeptide, and nucleic acids encoding the same - Google Patents

Ifi206, a novel interferon-induced polypeptide, and nucleic acids encoding the same

Info

Publication number
WO2001068830A8
WO2001068830A8 PCT/US2001/008333 US0108333W WO0168830A8 WO 2001068830 A8 WO2001068830 A8 WO 2001068830A8 US 0108333 W US0108333 W US 0108333W WO 0168830 A8 WO0168830 A8 WO 0168830A8
Authority
WO
WIPO (PCT)
Prior art keywords
ifi206
provides
expression
nucleic acids
same
Prior art date
Application number
PCT/US2001/008333
Other languages
French (fr)
Other versions
WO2001068830A1 (en
Inventor
David A Lewin
Sean Adams
Original Assignee
Curagen Corp
Genentech Inc
David A Lewin
Sean Adams
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Curagen Corp, Genentech Inc, David A Lewin, Sean Adams filed Critical Curagen Corp
Priority to EP01918720A priority Critical patent/EP1282696A4/en
Priority to JP2001567314A priority patent/JP2004522405A/en
Priority to AU4576501A priority patent/AU4576501A/en
Priority to CA002402877A priority patent/CA2402877A1/en
Publication of WO2001068830A1 publication Critical patent/WO2001068830A1/en
Publication of WO2001068830A8 publication Critical patent/WO2001068830A8/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2217/00—Genetically modified animals
    • A01K2217/05—Animals comprising random inserted nucleic acids (transgenic)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

Abstract

The present invention provides novel mouse interferon-inducible proteins (IFI206 and naturally occuring variants) modulated under conditions that affect metabolic status and the polynucleotides that identify and encode IFI206. The invention provides for genetically engineered expression vectors and host cells comprising the nucleic acid sequence encoding IFI206 and for a method for producing the protein. The invention also provides pharmaceutical compositions containing IFI206 and the use of such compositions for the prevention or treatment of diseases associated with the expression of IFI206. Additionally, the invention provides antisense molecules to IFI206 and their use in the treatment of diseases associated with the expression of IFI206. The invention also provides diagnostic assays that utilize polynucleotides that hybridize with naturally occurring sequences encoding IFI206 and antibodies that specifically bind to the protein.
PCT/US2001/008333 2000-03-02 2001-03-13 Ifi206, a novel interferon-induced polypeptide, and nucleic acids encoding the same WO2001068830A1 (en)

Priority Applications (4)

Application Number Priority Date Filing Date Title
EP01918720A EP1282696A4 (en) 2000-03-13 2001-03-13 Ifi206, a novel interferon-induced polypeptide, and nucleic acids encoding the same
JP2001567314A JP2004522405A (en) 2000-03-13 2001-03-13 IFI206, novel interferon-derived polypeptide and nucleic acid encoding the same
AU4576501A AU4576501A (en) 2000-03-02 2001-03-13 Ifi206, a novel interferon-induced polypeptide, and nucleic acids encoding the same
CA002402877A CA2402877A1 (en) 2000-03-13 2001-03-13 Ifi206, a novel interferon-induced polypeptide, and nucleic acids encoding the same

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US18651300P 2000-03-02 2000-03-02
US18871600P 2000-03-13 2000-03-13
US60/188,716 2000-03-13

Publications (2)

Publication Number Publication Date
WO2001068830A1 WO2001068830A1 (en) 2001-09-20
WO2001068830A8 true WO2001068830A8 (en) 2002-01-10

Family

ID=26882161

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2001/008333 WO2001068830A1 (en) 2000-03-02 2001-03-13 Ifi206, a novel interferon-induced polypeptide, and nucleic acids encoding the same

Country Status (1)

Country Link
WO (1) WO2001068830A1 (en)

Also Published As

Publication number Publication date
WO2001068830A1 (en) 2001-09-20

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