WO2001062282A3 - Adjuvants for vaccines - Google Patents

Adjuvants for vaccines Download PDF

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Publication number
WO2001062282A3
WO2001062282A3 PCT/GB2001/000816 GB0100816W WO0162282A3 WO 2001062282 A3 WO2001062282 A3 WO 2001062282A3 GB 0100816 W GB0100816 W GB 0100816W WO 0162282 A3 WO0162282 A3 WO 0162282A3
Authority
WO
WIPO (PCT)
Prior art keywords
vaccines
adjuvants
responses
cell type
helper cell
Prior art date
Application number
PCT/GB2001/000816
Other languages
French (fr)
Other versions
WO2001062282A2 (en
Inventor
David Idris Pritchard
Original Assignee
Univ Nottingham
David Idris Pritchard
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Nottingham, David Idris Pritchard filed Critical Univ Nottingham
Priority to AU33971/01A priority Critical patent/AU3397101A/en
Publication of WO2001062282A2 publication Critical patent/WO2001062282A2/en
Publication of WO2001062282A3 publication Critical patent/WO2001062282A3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/57—Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies

Landscapes

  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

Abstract

Vaccine compositions comprise an adjuvant capable of reducing T-helper cell type-1 responses and enhancing T-helper cell type-2 responses. The adjuvant preferably comprises a homoserine lactone.
PCT/GB2001/000816 2000-02-25 2001-02-26 Adjuvants for vaccines WO2001062282A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU33971/01A AU3397101A (en) 2000-02-25 2001-02-26 Adjuvants

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0004530.2A GB0004530D0 (en) 2000-02-25 2000-02-25 Adjuvants
GB0004530.2 2000-02-25

Publications (2)

Publication Number Publication Date
WO2001062282A2 WO2001062282A2 (en) 2001-08-30
WO2001062282A3 true WO2001062282A3 (en) 2001-12-27

Family

ID=9886439

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/GB2001/000816 WO2001062282A2 (en) 2000-02-25 2001-02-26 Adjuvants for vaccines

Country Status (3)

Country Link
AU (1) AU3397101A (en)
GB (1) GB0004530D0 (en)
WO (1) WO2001062282A2 (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CZ20022748A3 (en) 2000-02-21 2004-03-17 Pharmexa A/S Novel method for controlling amyloid content
MY144532A (en) 2001-08-20 2011-09-30 Lundbeck & Co As H Novel method for down-regulation of amyloid

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5776974A (en) * 1993-07-02 1998-07-07 The University Of Nottingham Immunosuppressant compounds

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5776974A (en) * 1993-07-02 1998-07-07 The University Of Nottingham Immunosuppressant compounds

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
SEN L ET AL: "HOOKWORM BURDEN REDUCTIONS IN BALB/C MICE VACCINATED WITH RECOMBINANT ANCYLOSTOMA SECRETED PROTEINS (ASPS) FROM ANCYLOSTOMA DUODENALE, ANCYLOSTOMA CANINUM AND NECATOR AMERICANUS", VACCINE, BUTTERWORTH SCIENTIFIC. GUILDFORD, GB, vol. 18, no. 11/12, January 2000 (2000-01-01), pages 1096 - 1102, XP001005230, ISSN: 0264-410X *
TELFORD G ET AL: "THE PSEUDOMONAS AERUGINOSA QUORUM-SENSING SIGNAL MOLECULE N-(3-OXODODENCANOYL)-L-HOMOSERINE LACTONE HAS IMMUNOMODULATORY ACTIVITY", INFECTION AND IMMUNITY, AMERICAN SOCIETY FOR MICROBIOLOGY. WASHINGTON, US, vol. 66, no. 1, January 1998 (1998-01-01), pages 36 - 42, XP001007928, ISSN: 0019-9567 *

Also Published As

Publication number Publication date
GB0004530D0 (en) 2000-04-19
WO2001062282A2 (en) 2001-08-30
AU3397101A (en) 2001-09-03

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