WO2001056539A1 - Enhanced efficacy aluminum-zirconium antiperspirants and methods for making - Google Patents

Enhanced efficacy aluminum-zirconium antiperspirants and methods for making Download PDF

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Publication number
WO2001056539A1
WO2001056539A1 PCT/US2000/033168 US0033168W WO0156539A1 WO 2001056539 A1 WO2001056539 A1 WO 2001056539A1 US 0033168 W US0033168 W US 0033168W WO 0156539 A1 WO0156539 A1 WO 0156539A1
Authority
WO
WIPO (PCT)
Prior art keywords
aluminum
zirconium
band
solution
percent
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/US2000/033168
Other languages
English (en)
French (fr)
Inventor
Li Zijun
Jawahar Chunilal Parekh
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Reheis Co Inc
Original Assignee
Reheis Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Reheis Co Inc filed Critical Reheis Co Inc
Priority to JP2001556231A priority Critical patent/JP2003523970A/ja
Priority to AU2001219520A priority patent/AU2001219520B2/en
Priority to EP00982496A priority patent/EP1251825A4/en
Priority to CA002398056A priority patent/CA2398056A1/en
Priority to AU1952001A priority patent/AU1952001A/xx
Publication of WO2001056539A1 publication Critical patent/WO2001056539A1/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q15/00—Anti-perspirants or body deodorants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
    • A61K8/28—Zirconium; Compounds thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/34—Alcohols
    • A61K8/345—Alcohols containing more than one hydroxy group
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
    • A61K8/44—Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/58—Metal complex; Coordination compounds

Definitions

  • This invention relates to a method of making aluminum-
  • Aluminum halide antiperspirant compounds are well known.
  • zirconium As the concentration of zirconium increases, more of zirconium increases.
  • Patent 3,507,896 to Jones et al and can be made by reacting
  • Al and Zr Aluminum- zirconium
  • antiperspirants are generally of three types; a) fast reacting
  • Al 3+ ion which consists of monomers, designated as Al a ;
  • Al c amorphous solids
  • AlCl 3 -6H 2 0 consists of 96% monomeric Al a species
  • Bands II and III designate
  • Band V designates small molecules that do
  • antiperspirant compositions exhibit more than 60% of aluminum
  • Al 3+ monomers hereinafter Al a ;
  • Al b Al b
  • Al c high molecular weight aluminum hydroxide complexes
  • aluminum species are monomeric .
  • Still another method used is 27 A1 nuclear magnetic
  • NMR nuclear magnetic resonance
  • the present method comprises forming a reaction mixture
  • composition contains monomeric Al a species of at least 25%, and
  • the Figure is a graph of 27 A1 nuclear magnetic resonance
  • the present invention provides a direct method for making
  • the present process further eliminates the need for
  • Suitable zirconium compounds have the formula ZrO(OH) 2 _
  • (2-ab) is greater than or equal to zero; and X is as defined
  • Suitable polyhydric alcohols have at least two carbon
  • polyaliphatic or polyhydroxy compounds are also suitable.
  • Suitable examples include propylene glycol , butylene glycol,
  • the amount of polyhydric alcohol employed is 20 to
  • Amino acids are optionally used as a buffer to maintain a
  • carboxyl groups in the molecule such as glycine.
  • amino acid compounds include alkaline, alkaline, and others.
  • the buffer should provide a solution pH of at least 2.5.
  • the invention further prepares Al-Zr complexes having a
  • the aluminum- zirconium active formed is monitored by high
  • polymeric aluminum species by size.
  • the antiperspirant composition of the invention contains more than 60%, preferably 70-85% and up to 90% of Al species
  • Al species is by conventional ferron analysis.
  • a reaction mixture was made of Al powder, aluminum halide
  • halide solutions are available at a concentration of about
  • the reaction is continued at a temperature of about 100-
  • Al : Zr ratio is 3.3-3.6, with a preferred solids concentration
  • the desired product has an HPLC
  • the product solution can be spray dried if desired to
  • the atomic ratio of Al : Zr is 3.4.
  • reaction mixture was filtered and the clear solution collected .
  • Al : Zr was 3.4.
  • the ratio of glycine : Zr was 1.4.
  • the solution was filtered.
  • Ferron analysis was 34.7% Al a ; 5.7% Al b ; and 59.6% Al c .
  • Example 7 32.7 0
  • Example 8 43.3 0

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Birds (AREA)
  • Epidemiology (AREA)
  • Emergency Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Inorganic Chemistry (AREA)
  • Cosmetics (AREA)
PCT/US2000/033168 2000-02-01 2000-12-06 Enhanced efficacy aluminum-zirconium antiperspirants and methods for making Ceased WO2001056539A1 (en)

Priority Applications (5)

Application Number Priority Date Filing Date Title
JP2001556231A JP2003523970A (ja) 2000-02-01 2000-12-06 効果が増強されたアルミニウム−ジルコニウム制汗剤
AU2001219520A AU2001219520B2 (en) 2000-02-01 2000-12-06 Enhanced efficacy aluminum-zirconium antiperspirants and methods for making
EP00982496A EP1251825A4 (en) 2000-02-01 2000-12-06 ALUMINUM ZIRCONIUM ANTITRANE SPIRANTS WITH INCREASED EFFECTIVENESS AND METHOD FOR THE PRODUCTION THEREOF
CA002398056A CA2398056A1 (en) 2000-02-01 2000-12-06 Enhanced efficacy aluminum-zirconium antiperspirants and methods for making
AU1952001A AU1952001A (en) 2000-02-01 2000-12-06 Enhanced efficacy aluminum-zirconium antiperspirants and methods for making

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US09/496,168 US6451296B1 (en) 2000-02-01 2000-02-01 Enhanced efficacy aluminum-zirconium antiperspirants and methods for making
US09/496,168 2000-02-01

Publications (1)

Publication Number Publication Date
WO2001056539A1 true WO2001056539A1 (en) 2001-08-09

Family

ID=23971532

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2000/033168 Ceased WO2001056539A1 (en) 2000-02-01 2000-12-06 Enhanced efficacy aluminum-zirconium antiperspirants and methods for making

Country Status (6)

Country Link
US (1) US6451296B1 (https=)
EP (1) EP1251825A4 (https=)
JP (1) JP2003523970A (https=)
AU (2) AU2001219520B2 (https=)
CA (1) CA2398056A1 (https=)
WO (1) WO2001056539A1 (https=)

Cited By (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6649152B2 (en) 2000-10-25 2003-11-18 The Gillette Company Aluminum-zirconium antiperspirant salts with high peak 5 Al content
US6663854B1 (en) 2002-06-19 2003-12-16 Yan-Fei Shen Aluminum-zirconium antiperspirant salts made with zirconium salts having low Zr:Cl ratio
EP1398023A1 (en) * 2002-09-16 2004-03-17 Reheis, Inc. Antiperspirant composition and method of preparation thereof
US6719965B2 (en) 2002-02-19 2004-04-13 Unilever Home & Personal Care Usa Division Of Conopco, Inc. Antiperspirant or deodorant composition
US6726901B2 (en) 2002-05-09 2004-04-27 The Gillette Company Stabilized antiperspirant compositions containing aluminum-zirconium salts with low M:Cl ratio
US6960338B2 (en) 2002-06-28 2005-11-01 Reheis, Inc. Amino acid free stable aluminum/zirconium antiperspirant solution
US7153495B2 (en) 2004-06-10 2006-12-26 Reheis, Inc. Fragrance friendly and cost effective antiperspirant actives and method of making the same
EP1727510A4 (en) * 2004-03-24 2008-04-16 Reheis Inc ANTI-TRANSPIRANT ACTIVE INGREDIENTS BASED ON ALUMINUM HALIDES AND A METAL CATION SALT

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040091436A1 (en) * 2002-11-12 2004-05-13 Zijun Li Antiperspirant compositions of enhanced efficacy containing strontium
GB0304508D0 (en) * 2003-02-27 2003-04-02 Unilever Plc Antiperspirant actives and compositions
US7105691B2 (en) * 2003-06-26 2006-09-12 Colgate-Palmolive Company Aluminum / zirconium / glycine antiperspirant actives stabilized with Betaine
US6902724B1 (en) 2004-03-24 2005-06-07 Reheis, Inc. Enhanced efficacy basic aluminum halides, antiperspirant active compositions and methods for making
US8801909B2 (en) * 2006-01-06 2014-08-12 Nextchem, Llc Polymetal hydroxychloride processes and compositions: enhanced efficacy antiperspirant salt compositions
US7846318B2 (en) * 2006-01-06 2010-12-07 Nextchem, Llc Polyaluminum chloride and aluminum chlorohydrate, processes and compositions: high-basicity and ultra high-basicity products
US9463985B2 (en) 2010-11-02 2016-10-11 Colgate-Palmolive Company Aluminum salt containing high percentage of Al30
WO2012060817A1 (en) 2010-11-02 2012-05-10 Colgate-Palmolive Company Antiperspirant active compositions and manufacture thereof
BR112013024919A2 (pt) 2011-04-26 2016-12-20 Colgate Palmolive Co composições contendo cátions de polihidroxioxoalumínio e fabricação destas
EP2702007B1 (en) 2011-04-26 2018-11-14 Colgate-Palmolive Company Antiperspirant active compositions and manufacture thereof

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4871525A (en) * 1986-10-24 1989-10-03 Westwood Chemical Corporation Antiperspirant composition and method of preparation
US5939057A (en) * 1994-11-02 1999-08-17 Provancal; Stephen J. Method of making polyhydric alcohol solutions of enhanced efficacy antiperspirant actives
US6126928A (en) * 1999-08-24 2000-10-03 The Procter & Gamble Company Compositions containing solubilized, acid-enhanced antiperspirant active
US6149897A (en) * 1999-08-24 2000-11-21 The Procter & Gamble Company Process for making anhydrous compositions containing solubilized, enhanced antiperspirant active

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3507896A (en) 1968-10-23 1970-04-21 Armour Pharma Method of making alcohol-soluble complexes of aluminum
US3981986A (en) 1973-11-23 1976-09-21 Armour Pharmaceutical Company Zirconium-aluminum-polyol buffered anti-perspirant complexes
US4359456A (en) 1976-01-14 1982-11-16 Lever Brothers Company Antiperspirant activity of basic aluminum compounds
US5356609A (en) 1986-01-08 1994-10-18 Westwood Chemical Corp. Method for preparing basic aluminum halides by reacting aluminum halide with aluminum
US5330751A (en) * 1988-04-14 1994-07-19 The Gilette Company Antiperspirant and method of making same
EP0404533A1 (en) * 1989-06-23 1990-12-27 The Procter & Gamble Company Liquid solubilized antiperspirant actives and processes for preparing the same
CA2046170A1 (en) 1990-07-10 1992-01-11 Morton Lawrence Barr Basic aluminum antiperspirant active materials having enhanced activity, antiperspirant active compositions containing such materials, and methods for preparation of such materials and compositions
US5179220A (en) 1991-07-01 1993-01-12 Somerville Technology Group, Inc. Non-aqueous solutions of aluminum and aluminum-zirconium compounds
US6010688A (en) * 1997-06-25 2000-01-04 The Gillette Company Polyhydric alcohol stabilized antiperspirant salt solutions
US5955064A (en) * 1997-10-21 1999-09-21 Westwood Chemical Corporation Enhanced efficacy stable antiperspirant active solution and method of making same

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4871525A (en) * 1986-10-24 1989-10-03 Westwood Chemical Corporation Antiperspirant composition and method of preparation
US5939057A (en) * 1994-11-02 1999-08-17 Provancal; Stephen J. Method of making polyhydric alcohol solutions of enhanced efficacy antiperspirant actives
US6126928A (en) * 1999-08-24 2000-10-03 The Procter & Gamble Company Compositions containing solubilized, acid-enhanced antiperspirant active
US6149897A (en) * 1999-08-24 2000-11-21 The Procter & Gamble Company Process for making anhydrous compositions containing solubilized, enhanced antiperspirant active

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
See also references of EP1251825A4 *

Cited By (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6649152B2 (en) 2000-10-25 2003-11-18 The Gillette Company Aluminum-zirconium antiperspirant salts with high peak 5 Al content
US6991780B2 (en) 2000-10-25 2006-01-31 The Gillette Company Aluminum-zirconium antiperspirant salts with low M:CI ratio
US6719965B2 (en) 2002-02-19 2004-04-13 Unilever Home & Personal Care Usa Division Of Conopco, Inc. Antiperspirant or deodorant composition
US6726901B2 (en) 2002-05-09 2004-04-27 The Gillette Company Stabilized antiperspirant compositions containing aluminum-zirconium salts with low M:Cl ratio
US6663854B1 (en) 2002-06-19 2003-12-16 Yan-Fei Shen Aluminum-zirconium antiperspirant salts made with zirconium salts having low Zr:Cl ratio
US6960338B2 (en) 2002-06-28 2005-11-01 Reheis, Inc. Amino acid free stable aluminum/zirconium antiperspirant solution
US7144571B2 (en) 2002-06-28 2006-12-05 Reheis, Inc. Amino acid free stable aluminum/zirconium antiperspirant solution
EP1398023A1 (en) * 2002-09-16 2004-03-17 Reheis, Inc. Antiperspirant composition and method of preparation thereof
EP1727510A4 (en) * 2004-03-24 2008-04-16 Reheis Inc ANTI-TRANSPIRANT ACTIVE INGREDIENTS BASED ON ALUMINUM HALIDES AND A METAL CATION SALT
US7153495B2 (en) 2004-06-10 2006-12-26 Reheis, Inc. Fragrance friendly and cost effective antiperspirant actives and method of making the same

Also Published As

Publication number Publication date
JP2003523970A (ja) 2003-08-12
US6451296B1 (en) 2002-09-17
AU2001219520B2 (en) 2005-01-27
CA2398056A1 (en) 2001-08-09
EP1251825A1 (en) 2002-10-30
EP1251825A4 (en) 2008-08-20
AU1952001A (en) 2001-08-14

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