WO2001055335A3 - Procedes et materiaux se rapportant a des polypeptides et polynucleotides semblables a des recepteurs de leucocytes de type immunoglobuline (lir) - Google Patents

Procedes et materiaux se rapportant a des polypeptides et polynucleotides semblables a des recepteurs de leucocytes de type immunoglobuline (lir) Download PDF

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Publication number
WO2001055335A3
WO2001055335A3 PCT/US2001/002570 US0102570W WO0155335A3 WO 2001055335 A3 WO2001055335 A3 WO 2001055335A3 US 0102570 W US0102570 W US 0102570W WO 0155335 A3 WO0155335 A3 WO 0155335A3
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WO
WIPO (PCT)
Prior art keywords
seq
polynucleotides
polypeptides
mrna
lir
Prior art date
Application number
PCT/US2001/002570
Other languages
English (en)
Other versions
WO2001055335A2 (fr
Inventor
Bryan J Boyle
Chiauyun Kuo
Nancy K Mize
Dana A Haley
Matthew C Arterburn
Y Tom Tang
Ping Zhou
Chenghua Liu
Vinod Asundi
Radoje T Drmanac
George Yeung
Servando Palencia
Original Assignee
Hyseq Inc
Bryan J Boyle
Chiauyun Kuo
Nancy K Mize
Dana A Haley
Matthew C Arterburn
Y Tom Tang
Ping Zhou
Chenghua Liu
Vinod Asundi
Radoje T Drmanac
George Yeung
Servando Palencia
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hyseq Inc, Bryan J Boyle, Chiauyun Kuo, Nancy K Mize, Dana A Haley, Matthew C Arterburn, Y Tom Tang, Ping Zhou, Chenghua Liu, Vinod Asundi, Radoje T Drmanac, George Yeung, Servando Palencia filed Critical Hyseq Inc
Priority to CA002398251A priority Critical patent/CA2398251A1/fr
Priority to AU3300301A priority patent/AU3300301A/xx
Priority to AU2001233003A priority patent/AU2001233003B2/en
Priority to JP2001561140A priority patent/JP2004524001A/ja
Priority to EP01905085A priority patent/EP1261735A4/fr
Publication of WO2001055335A2 publication Critical patent/WO2001055335A2/fr
Publication of WO2001055335A3 publication Critical patent/WO2001055335A3/fr

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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70503Immunoglobulin superfamily
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14Hydrolases (3)
    • C12N9/16Hydrolases (3) acting on ester bonds (3.1)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14Hydrolases (3)
    • C12N9/48Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6424Serine endopeptidases (3.4.21)
    • C12N9/6432Coagulation factor Xa (3.4.21.6)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y304/00Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
    • C12Y304/21Serine endopeptidases (3.4.21)
    • C12Y304/21006Coagulation factor Xa (3.4.21.6)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biophysics (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

L'invention concerne des nouveaux polynucléotides et polypeptides codés par de tels polynucléotides ainsi que leurs mutants ou variants qui correspondent à un nouveau polypeptide humain sécrété semblable à un récepteur de leucocyte de type immunoglobuline. Ces polynucléotides renferment des séquences d'acide nucléique isolées de banques d'cADN préparées à partir d'une banque d'cADN préparée à partir d'un mARN de leucocyte humain (Laboratoires GIBCO) (SEQ ID NO:1, SEQ ID NO:16); d'un mARN du cerveau d'un nourrisson (Columbia University) (SEQ ID NO: 35); d'un mARN de glande mammaire humaine (Invitrogène) (SEQ ID NO: 47); et d'un mARN de moelle osseuse (Clontech) (SEQ ID NO: 63). D'autres aspects de l'invention concernent des vecteurs contenant des procédés de production de polypeptides humains sécrétés semblables à LIR, ainsi que des anticorps propres à de tels polypeptides.
PCT/US2001/002570 2000-01-25 2001-01-25 Procedes et materiaux se rapportant a des polypeptides et polynucleotides semblables a des recepteurs de leucocytes de type immunoglobuline (lir) WO2001055335A2 (fr)

Priority Applications (5)

Application Number Priority Date Filing Date Title
CA002398251A CA2398251A1 (fr) 2000-01-25 2001-01-25 Procedes et materiaux se rapportant a des polypeptides et polynucleotides semblables a des recepteurs de leucocytes de type immunoglobuline (lir)
AU3300301A AU3300301A (en) 2000-01-25 2001-01-25 Methods and materials relating to leukocyte immunoglobulin receptor-like (lir-like) polypeptides and polynucleotides
AU2001233003A AU2001233003B2 (en) 2000-01-25 2001-01-25 Methods and materials relating to leukocyte immunoglobulin receptor-like (lir-like) polypeptides and polynucleotides
JP2001561140A JP2004524001A (ja) 2000-01-25 2001-01-25 白血球免疫グロブリン受容体(lir様)ポリペプチドおよびポリヌクレオチドに関する方法と材料
EP01905085A EP1261735A4 (fr) 2000-01-25 2001-01-25 Procedes et materiaux se rapportant a des polypeptides et polynucleotides semblables a des recepteurs de leucocytes de type immunoglobuline (lir)

Applications Claiming Priority (13)

Application Number Priority Date Filing Date Title
US49140400A 2000-01-25 2000-01-25
US09/491,404 2000-01-25
US49691400A 2000-02-03 2000-02-03
US09/496,914 2000-02-03
US51970500A 2000-03-07 2000-03-07
US09/519,705 2000-03-07
US56087500A 2000-04-27 2000-04-27
US09/560,875 2000-04-27
US09/524,454 2000-05-19
US64261000A 2000-08-17 2000-08-17
US09/642,610 2000-08-17
US75151800A 2000-12-29 2000-12-29
US09/751,518 2000-12-29

Publications (2)

Publication Number Publication Date
WO2001055335A2 WO2001055335A2 (fr) 2001-08-02
WO2001055335A3 true WO2001055335A3 (fr) 2002-03-07

Family

ID=46397760

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2001/002570 WO2001055335A2 (fr) 2000-01-25 2001-01-25 Procedes et materiaux se rapportant a des polypeptides et polynucleotides semblables a des recepteurs de leucocytes de type immunoglobuline (lir)

Country Status (4)

Country Link
EP (1) EP1261735A4 (fr)
AU (2) AU3300301A (fr)
CA (1) CA2398251A1 (fr)
WO (1) WO2001055335A2 (fr)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1453540A4 (fr) * 2001-11-14 2005-06-01 Immunex Corp Modulation de la fonction des lir dans le traitement de la polyarthrite rhumatoide
AU2002952993A0 (en) * 2002-11-29 2002-12-12 The Corporation Of The Trustees Of The Order Of The Sisters Of Mercy In Queensland Therapeutic and diagnostic agents
US20080248011A1 (en) * 2004-01-27 2008-10-09 Medical And Biological Laboratories Co., Ltd. Methods for Isolating Monocytes
CA2624135C (fr) * 2005-09-29 2015-06-30 Eisai R & D Management Co., Ltd. Molecule d'adhesion aux lymphocytes t et anticorps connexe
EP2525813B1 (fr) 2010-01-20 2017-01-04 Merck Sharp & Dohme Corp. Anticorps anti-ilt5 et fragments d'anticorps se liant à ilt5
EP2525822B1 (fr) 2010-01-20 2017-05-10 Merck Sharp & Dohme Corp. Immunorégulation par des anticorps anti-ilt5 et fragments d'anticorps se liant à ilt5
CN107002091A (zh) 2014-10-01 2017-08-01 植物保健公司 过敏反应激发子肽及其用途
JP2017532981A (ja) 2014-10-01 2017-11-09 プラント ヘルス ケア インコーポレイテッド 破壊された過敏感反応ボックスを有するエリシターペプチド及びその使用
WO2017176588A1 (fr) 2016-04-06 2017-10-12 Plant Health Care, Inc. Microbes bénéfiques pour l'administration de peptides effecteurs ou de protéines effectrices et leur utilisation
US10793608B2 (en) 2016-04-06 2020-10-06 Plant Health Care, Inc. Hypersensitive response elicitor-derived peptides and use thereof

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000078962A1 (fr) * 1999-06-18 2000-12-28 Immunex Corporation Recepteur de surface de leucocyte (lsr), un adnc de la superfamille des ig exprime dans les leucocytes humains

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2001509030A (ja) * 1997-01-21 2001-07-10 ヒューマン ジノーム サイエンシーズ,インコーポレイテッド Fcレセプターおよびポリペプチド
WO1998045435A2 (fr) * 1997-04-10 1998-10-15 Genetics Institute, Inc. MARQUEURS SECRETES DE SEQUENCE EXPRIMEE (sEST)
US6448035B1 (en) * 1997-04-24 2002-09-10 Immunex Corporation Family of immunoregulators designated leukocyte immunoglobulin-like receptor (LIR)
US6020161A (en) * 1997-08-19 2000-02-01 Smithkline Beecham Corporation PIGR-1, a member of immunoglobulin gene superfamily
EP0905237A3 (fr) * 1997-08-25 1999-12-22 Smithkline Beecham Corporation PIGR-2 appartenant au sous-ordre des immunoglobulines
JP2002540763A (ja) * 1999-02-10 2002-12-03 ヒューマン ジノーム サイエンシーズ, インコーポレイテッド 33個のヒト分泌タンパク質
WO2001000673A1 (fr) * 1999-06-30 2001-01-04 Millennium Pharmaceuticals, Inc. Proteines associees aux membranes et secretees, et leurs utilisations
CA2382015A1 (fr) * 1999-08-17 2001-02-22 Incyte Genomics, Inc. Proteines associees a la membrane

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000078962A1 (fr) * 1999-06-18 2000-12-28 Immunex Corporation Recepteur de surface de leucocyte (lsr), un adnc de la superfamille des ig exprime dans les leucocytes humains

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
See also references of EP1261735A4 *

Also Published As

Publication number Publication date
WO2001055335A2 (fr) 2001-08-02
EP1261735A4 (fr) 2005-04-06
CA2398251A1 (fr) 2001-08-02
AU2001233003B2 (en) 2006-02-09
AU3300301A (en) 2001-08-07
EP1261735A2 (fr) 2002-12-04

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