WO2001051518A3 - Molecules d'acide nucleique isolees codant pour une molecule de semaphorine humaine et utilisations correspondantes - Google Patents

Molecules d'acide nucleique isolees codant pour une molecule de semaphorine humaine et utilisations correspondantes Download PDF

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Publication number
WO2001051518A3
WO2001051518A3 PCT/US2001/001275 US0101275W WO0151518A3 WO 2001051518 A3 WO2001051518 A3 WO 2001051518A3 US 0101275 W US0101275 W US 0101275W WO 0151518 A3 WO0151518 A3 WO 0151518A3
Authority
WO
WIPO (PCT)
Prior art keywords
nucleic acids
acids encoding
encoding human
human semaphorin
molecules
Prior art date
Application number
PCT/US2001/001275
Other languages
English (en)
Other versions
WO2001051518A2 (fr
Inventor
Andrew John George Simpson
Ricardo Correa
Souzo Sandro De
Original Assignee
Ludwig Inst Cancer Res
Andrew John George Simpson
Ricardo Correa
Souzo Sandro De
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ludwig Inst Cancer Res, Andrew John George Simpson, Ricardo Correa, Souzo Sandro De filed Critical Ludwig Inst Cancer Res
Priority to AU2001232804A priority Critical patent/AU2001232804A1/en
Publication of WO2001051518A2 publication Critical patent/WO2001051518A2/fr
Publication of WO2001051518A3 publication Critical patent/WO2001051518A3/fr

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4702—Regulators; Modulating activity
    • C07K14/4703—Inhibitors; Suppressors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

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  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

Abstract

L'invention concerne des molécules d'acide nucléique isolées codant pour la sémaphorine humaine R/6B. Ces molécules sont associées au cancer, tel que le cancer du sein. L'invention concerne également les protéines codées par ces molécules, ainsi que les oligonucléotides les hybridant. L'invention porte enfin sur différentes utilisations de ces molécules.
PCT/US2001/001275 2000-01-14 2001-01-12 Molecules d'acide nucleique isolees codant pour une molecule de semaphorine humaine et utilisations correspondantes WO2001051518A2 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2001232804A AU2001232804A1 (en) 2000-01-14 2001-01-12 Nucleic acids encoding human semaphorin proteins and use thereof

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US48361800A 2000-01-14 2000-01-14
US09/483,618 2000-01-14

Publications (2)

Publication Number Publication Date
WO2001051518A2 WO2001051518A2 (fr) 2001-07-19
WO2001051518A3 true WO2001051518A3 (fr) 2002-09-19

Family

ID=23920807

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2001/001275 WO2001051518A2 (fr) 2000-01-14 2001-01-12 Molecules d'acide nucleique isolees codant pour une molecule de semaphorine humaine et utilisations correspondantes

Country Status (2)

Country Link
AU (1) AU2001232804A1 (fr)
WO (1) WO2001051518A2 (fr)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2003532383A (ja) * 2000-01-18 2003-11-05 ヒューマン ジノーム サイエンシーズ， インコーポレイテッド ヒトポリヌクレオチド、ポリペプチド、および抗体
WO2002074994A2 (fr) * 2000-11-07 2002-09-26 Ludwig Institute For Cancer Research Methode de sequençage orestes amelioree
US7781413B2 (en) 2001-10-31 2010-08-24 Board Of Regents, The University Of Texas System SEMA3B inhibits tumor growth and induces apoptosis in cancer cells
US20070010433A1 (en) * 2002-07-11 2007-01-11 Sema Aps Use of compounds capable of inhibiting the proteolytic processing of semaphorins for prevention, treatment, diagnosis and prognosis of an invasive disease

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0896058A1 (fr) * 1995-12-06 1999-02-10 Sumitomo Pharmaceuticals Company, Limited Nouvelle semaphorine z et gene la codant

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0896058A1 (fr) * 1995-12-06 1999-02-10 Sumitomo Pharmaceuticals Company, Limited Nouvelle semaphorine z et gene la codant

Non-Patent Citations (5)

* Cited by examiner, † Cited by third party
Title
CORREA ET AL: "Human semaphorin 6B [(HSA)SEMA6B], a novel human class 6 semaphorin gene: alternative splicing and all-trans-retinoic acid-dependent downregulation in glioblastoma cell lines", EMBL DATA BASE - EMBL:AF216389, 29 July 2000 (2000-07-29), XP002171337 *
CORREA ET AL: "Human Semaphorin 6B [(HSA)SEMA6B], a novel human class 6 semaphorin gene: Alternative splicing and all-trans-retinoic acid-dependent downregulation in glioblastoma cell lines", GENOMICS, vol. 73, 12 April 2001 (2001-04-12), pages 343 - 348, XP002171339 *
ECKHARDT F ET AL: "A NOVEL TRANSMEMBRANE SEMAPHORIN CAN BIND C-SRC", MOLECULAR AND CELLULAR NEUROSCIENCES,SAN DIEGO,US, vol. 9, 1997, pages 409 - 419, XP000996620, ISSN: 1044-7431 *
KLOSTERMANN ET AL: "The orthologous human and murine semaphorin 6A-1 proteins (SEMA6A-1/Sema6A-1) bind to the enabled/vasodilator-stimulated phosphoprotein-like protein (EVL) via a novel carboxy-terminal zyxin-like domain", JOURNA LOF BIOLOGICAL CHEMISTRY, vol. 275, 15 December 2000 (2000-12-15), pages 39647 - 39653, XP002171338 *
SIMPSON: "The FAPESP/LICR human cancer genome project; http://www.ludwig.org.br/ORESTES", EMBL DATA BASE - EMBL:AW054434, 27 September 1999 (1999-09-27), XP002171336 *

Also Published As

Publication number Publication date
WO2001051518A2 (fr) 2001-07-19
AU2001232804A1 (en) 2001-07-24

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