WO2001046397A3 - Kinases humaines - Google Patents

Kinases humaines Download PDF

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Publication number
WO2001046397A3
WO2001046397A3 PCT/US2000/035304 US0035304W WO0146397A3 WO 2001046397 A3 WO2001046397 A3 WO 2001046397A3 US 0035304 W US0035304 W US 0035304W WO 0146397 A3 WO0146397 A3 WO 0146397A3
Authority
WO
WIPO (PCT)
Prior art keywords
pkin
human kinases
provides
kinases
polynucleotides
Prior art date
Application number
PCT/US2000/035304
Other languages
English (en)
Other versions
WO2001046397A2 (fr
Inventor
Junming Yang
Mariah R Baughn
Neil Burford
Janice Au-Young
Dyung Aina M Lu
Roopa Reddy
Henry Yue
Monique G Yao
Preeti Lal
Farrah A Khan
Original Assignee
Incyte Genomics Inc
Junming Yang
Mariah R Baughn
Neil Burford
Au Young Janice
Dyung Aina M Lu
Roopa Reddy
Henry Yue
Monique G Yao
Preeti Lal
Farrah A Khan
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Incyte Genomics Inc, Junming Yang, Mariah R Baughn, Neil Burford, Au Young Janice, Dyung Aina M Lu, Roopa Reddy, Henry Yue, Monique G Yao, Preeti Lal, Farrah A Khan filed Critical Incyte Genomics Inc
Priority to US10/168,582 priority Critical patent/US20040058426A1/en
Priority to EP00986741A priority patent/EP1242584A2/fr
Priority to AU22923/01A priority patent/AU2292301A/en
Priority to JP2001546895A priority patent/JP2003517838A/ja
Priority to CA002395102A priority patent/CA2395102A1/fr
Publication of WO2001046397A2 publication Critical patent/WO2001046397A2/fr
Publication of WO2001046397A3 publication Critical patent/WO2001046397A3/fr
Priority to US10/979,095 priority patent/US20060068481A1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/12—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
    • C12N9/1205—Phosphotransferases with an alcohol group as acceptor (2.7.1), e.g. protein kinases
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Wood Science & Technology (AREA)
  • Immunology (AREA)
  • Genetics & Genomics (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Obesity (AREA)
  • Microbiology (AREA)
  • Diabetes (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Cardiology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Enzymes And Modification Thereof (AREA)

Abstract

L'invention concerne les kinases humaines (PKIN) et des polynucléotides identifiant et codant pour les PKIN. L'invention concerne également des vecteurs d'expression, de cellules hôtes, des anticorps, des agonistes, et des antagonistes. L'invention concerne en outre des méthodes de diagnostic, de traitement ou de prévention des troubles associés à l'expression aberrante des PKIN.
PCT/US2000/035304 1999-12-23 2000-12-20 Kinases humaines WO2001046397A2 (fr)

Priority Applications (6)

Application Number Priority Date Filing Date Title
US10/168,582 US20040058426A1 (en) 2000-12-20 2000-12-20 Human kinases
EP00986741A EP1242584A2 (fr) 1999-12-23 2000-12-20 Kinases humaines
AU22923/01A AU2292301A (en) 1999-12-23 2000-12-20 Human kinases
JP2001546895A JP2003517838A (ja) 1999-12-23 2000-12-20 ヒトキナーゼ
CA002395102A CA2395102A1 (fr) 1999-12-23 2000-12-20 Kinases humaines
US10/979,095 US20060068481A1 (en) 1999-12-23 2004-11-02 Human kinases

Applications Claiming Priority (8)

Application Number Priority Date Filing Date Title
US17206699P 1999-12-23 1999-12-23
US60/172,066 1999-12-23
US17610700P 2000-01-14 2000-01-14
US60/176,107 2000-01-14
US17773100P 2000-01-21 2000-01-21
US60/177,731 2000-01-21
US17857300P 2000-01-28 2000-01-28
US60/178,573 2000-01-28

Related Child Applications (1)

Application Number Title Priority Date Filing Date
US10/979,095 Division US20060068481A1 (en) 1999-12-23 2004-11-02 Human kinases

Publications (2)

Publication Number Publication Date
WO2001046397A2 WO2001046397A2 (fr) 2001-06-28
WO2001046397A3 true WO2001046397A3 (fr) 2002-02-21

Family

ID=27496995

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2000/035304 WO2001046397A2 (fr) 1999-12-23 2000-12-20 Kinases humaines

Country Status (5)

Country Link
EP (1) EP1242584A2 (fr)
JP (1) JP2003517838A (fr)
AU (1) AU2292301A (fr)
CA (1) CA2395102A1 (fr)
WO (1) WO2001046397A2 (fr)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001096544A2 (fr) * 2000-06-15 2001-12-20 Millennium Pharmaceuticals, Inc. 53070, nouvel element de la famille des proteines kinases humaines et utilisations de celui-ci
AU2001255763A1 (en) * 2000-04-25 2001-11-07 Millennium Pharmaceuticals, Inc. 13295 novel protein kinase molecules and uses therefor
JP2003531617A (ja) * 2000-05-05 2003-10-28 メルク パテント ゲゼルシャフト ミット ベシュレンクテル ハフトング 新規セリン−トレオニン・キナーゼ
US6482935B1 (en) * 2000-05-24 2002-11-19 Applera Corporation Isolated human kinase proteins, nucleic acid molecules encoding human kinase proteins, and uses thereof
US7094587B2 (en) 2000-06-27 2006-08-22 Millennium Pharmaceuticals, Inc. 16002 Molecules and uses therefor
US6555352B2 (en) 2000-08-31 2003-04-29 Applera Corporation Isolated human kinase proteins, nucleic acid molecules encoding human kinase proteins, and uses thereof
AU2002220630A1 (en) * 2000-10-16 2002-04-29 Bayer Aktiengesellschaft Regulation of human serine-threonine protein kinase
EP1339866B1 (fr) * 2000-11-09 2010-09-01 University Of Virginia Patent Foundation Serine/threonine kinase specifique des testicules de l'homme
AU2002247060A1 (en) * 2001-01-12 2002-08-06 E.I. Dupont De Nemours And Company Novel inositol polyphosphate kinase genes and uses thereof
US6686176B2 (en) * 2001-01-23 2004-02-03 Applera Corporation Isolated human kinase proteins, nucleic acid molecules encoding human kinase proteins, and uses thereof
JP2003259878A (ja) * 2002-03-11 2003-09-16 Toyota Central Res & Dev Lab Inc 乳酸脱水素酵素をコードするｄｎａおよびその利用
WO2003102144A2 (fr) * 2002-05-29 2003-12-11 Curagen Corporation Compositions et methodes d'utilisation d'un recepteur de l'ephrine
EP1725869A4 (fr) * 2004-01-28 2007-10-31 Exelixis Inc Man2a utilises comme modificateurs de la voie igfr et leur procede d'utilisation

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000058473A2 (fr) * 1999-03-31 2000-10-05 Curagen Corporation Acides nucleiques comprenant des phases de lecture ouverte codant des polypeptides; «orfx»

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000058473A2 (fr) * 1999-03-31 2000-10-05 Curagen Corporation Acides nucleiques comprenant des phases de lecture ouverte codant des polypeptides; «orfx»

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
DATABASE EMBL [online] 14 February 2000 (2000-02-14), WATERSTON, XP002161690, Database accession no. AC023270 *
DATABASE EMBL 15 December 2000 (2000-12-15), STRAUSBERG, XP002161691, Database accession no. BF576072 *
DATABASE EMBL 8 May 1999 (1999-05-08), XP002161689, Database accession no. HSPD29807 *
DATABASE PROSITE November 1995 (1995-11-01), HUNTER ET AL., XP002161770, Database accession no. PDOC00100 *

Also Published As

Publication number Publication date
WO2001046397A2 (fr) 2001-06-28
AU2292301A (en) 2001-07-03
CA2395102A1 (fr) 2001-06-28
EP1242584A2 (fr) 2002-09-25
JP2003517838A (ja) 2003-06-03

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