WO2001040312A3 - Procede de criblage naif - Google Patents

Procede de criblage naif Download PDF

Info

Publication number
WO2001040312A3
WO2001040312A3 PCT/GB2000/004629 GB0004629W WO0140312A3 WO 2001040312 A3 WO2001040312 A3 WO 2001040312A3 GB 0004629 W GB0004629 W GB 0004629W WO 0140312 A3 WO0140312 A3 WO 0140312A3
Authority
WO
WIPO (PCT)
Prior art keywords
polypeptide
naive
screening method
target ligand
naïve
Prior art date
Application number
PCT/GB2000/004629
Other languages
English (en)
Other versions
WO2001040312A2 (fr
Inventor
Lucy Jessica Holt
Wildt Rudolf Maria Theodora De
Ian Tomlinson
Original Assignee
Diversys Ltd
Lucy Jessica Holt
Wildt Rudolf Maria Theodora De
Ian Tomlinson
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Diversys Ltd, Lucy Jessica Holt, Wildt Rudolf Maria Theodora De, Ian Tomlinson filed Critical Diversys Ltd
Priority to CA002392939A priority Critical patent/CA2392939A1/fr
Priority to AU17187/01A priority patent/AU1718701A/en
Priority to JP2001541066A priority patent/JP2003515331A/ja
Priority to EP00979803A priority patent/EP1234179A2/fr
Publication of WO2001040312A2 publication Critical patent/WO2001040312A2/fr
Publication of WO2001040312A3 publication Critical patent/WO2001040312A3/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70503—Immunoglobulin superfamily
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/04—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length on carriers
    • C07K1/047—Simultaneous synthesis of different peptide species; Peptide libraries

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Analytical Chemistry (AREA)
  • Cell Biology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Peptides Or Proteins (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

Abstract

La présente invention concerne un procédé d'isolation, à partir d'un répertoire de polypeptides naïfs n'ayant pas été présélectionnés avec un ligand cible spécifique, d'un polypeptide recherché capable d'interagir avec ledit ligand cible spécifique. Ce procédé consiste à cribler directement le répertoire de polypeptides naïfs avec le ligand cible afin d'identifier le polypeptide recherché.
PCT/GB2000/004629 1999-12-03 2000-12-04 Procede de criblage naif WO2001040312A2 (fr)

Priority Applications (4)

Application Number Priority Date Filing Date Title
CA002392939A CA2392939A1 (fr) 1999-12-03 2000-12-04 Procede de criblage naif
AU17187/01A AU1718701A (en) 1999-12-03 2000-12-04 Naive screening method
JP2001541066A JP2003515331A (ja) 1999-12-03 2000-12-04 ナイーブスクリーニング法
EP00979803A EP1234179A2 (fr) 1999-12-03 2000-12-04 Procede de criblage naif

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9928789.8A GB9928789D0 (en) 1999-12-03 1999-12-03 Naive screening method
GB9928789.8 1999-12-03

Publications (2)

Publication Number Publication Date
WO2001040312A2 WO2001040312A2 (fr) 2001-06-07
WO2001040312A3 true WO2001040312A3 (fr) 2002-01-17

Family

ID=10865786

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/GB2000/004629 WO2001040312A2 (fr) 1999-12-03 2000-12-04 Procede de criblage naif

Country Status (6)

Country Link
EP (1) EP1234179A2 (fr)
JP (1) JP2003515331A (fr)
AU (1) AU1718701A (fr)
CA (1) CA2392939A1 (fr)
GB (1) GB9928789D0 (fr)
WO (1) WO2001040312A2 (fr)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20020115068A1 (en) * 2000-06-23 2002-08-22 Ian Tomlinson Matrix screening method
US6815078B2 (en) 2002-03-06 2004-11-09 Eastman Kodak Company Substrate for protein microarray containing functionalized polymer
US7153896B2 (en) 2003-11-14 2006-12-26 Eastman Kodak Company Element for protein microarrays
US7235641B2 (en) 2003-12-22 2007-06-26 Micromet Ag Bispecific antibodies

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1990015070A1 (fr) * 1989-06-07 1990-12-13 Affymax Technologies N.V. Synthese a grande echelle de peptides immobilises
WO1992010092A1 (fr) * 1990-12-06 1992-06-25 Affymax Technologies N.V. Synthese de polymeres immobilises sur tres grande echelle
WO1999020749A1 (fr) * 1997-10-20 1999-04-29 Medical Research Council Procede de ciblage de banques de presentation de phages au moyen de ligands differents

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2319828A1 (fr) * 1998-01-29 1999-08-05 Miller, Samuel Series haute densite pour l'analyse des proteomes et procedes et compositions pour ces derniers
WO1999040434A1 (fr) * 1998-02-04 1999-08-12 Invitrogen Corporation Microsystemes et leurs mises en application

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1990015070A1 (fr) * 1989-06-07 1990-12-13 Affymax Technologies N.V. Synthese a grande echelle de peptides immobilises
WO1992010092A1 (fr) * 1990-12-06 1992-06-25 Affymax Technologies N.V. Synthese de polymeres immobilises sur tres grande echelle
WO1999020749A1 (fr) * 1997-10-20 1999-04-29 Medical Research Council Procede de ciblage de banques de presentation de phages au moyen de ligands differents

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
See also references of EP1234179A2 *

Also Published As

Publication number Publication date
GB9928789D0 (en) 2000-02-02
JP2003515331A (ja) 2003-05-07
CA2392939A1 (fr) 2001-06-07
EP1234179A2 (fr) 2002-08-28
AU1718701A (en) 2001-06-12
WO2001040312A2 (fr) 2001-06-07

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