WO2001040265A3 - Ligands for a target molecule and a method for indentifying them - Google Patents

Ligands for a target molecule and a method for indentifying them Download PDF

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Publication number
WO2001040265A3
WO2001040265A3 PCT/US2000/042515 US0042515W WO0140265A3 WO 2001040265 A3 WO2001040265 A3 WO 2001040265A3 US 0042515 W US0042515 W US 0042515W WO 0140265 A3 WO0140265 A3 WO 0140265A3
Authority
WO
WIPO (PCT)
Prior art keywords
ligands
target
indentifying
target molecule
specific
Prior art date
Application number
PCT/US2000/042515
Other languages
French (fr)
Other versions
WO2001040265A2 (en
Inventor
David J Hammond
Original Assignee
Vi Technologies Inc
David J Hammond
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Vi Technologies Inc, David J Hammond filed Critical Vi Technologies Inc
Priority to EP00992385A priority Critical patent/EP1237908A2/en
Priority to JP2001541020A priority patent/JP2004500350A/en
Priority to CA002392797A priority patent/CA2392797A1/en
Priority to AU43092/01A priority patent/AU4309201A/en
Publication of WO2001040265A2 publication Critical patent/WO2001040265A2/en
Publication of WO2001040265A3 publication Critical patent/WO2001040265A3/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Peptides Or Proteins (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

Abstract

Ligands that interact with a target, such as one present on a virus, can be more easily identified if false positive interactions (either specific or non-specific) are differentiated from the target-specific interaction. An improved method for screening a library of surface-immobilized ligands which bind to a target is presented. The method can be used for multiple screenings of the same surface-immobilized library for a number of different ligands.
PCT/US2000/042515 1999-12-02 2000-12-01 Ligands for a target molecule and a method for indentifying them WO2001040265A2 (en)

Priority Applications (4)

Application Number Priority Date Filing Date Title
EP00992385A EP1237908A2 (en) 1999-12-02 2000-12-01 Ligands for a target molecule and method for identifying them
JP2001541020A JP2004500350A (en) 1999-12-02 2000-12-01 Methods for identifying ligands for target molecules
CA002392797A CA2392797A1 (en) 1999-12-02 2000-12-01 Method of identifying a ligand for a target molecule
AU43092/01A AU4309201A (en) 1999-12-02 2000-12-01 Method of identifying a ligand for a target molecule

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US45311599A 1999-12-02 1999-12-02
US09/453,115 1999-12-02

Publications (2)

Publication Number Publication Date
WO2001040265A2 WO2001040265A2 (en) 2001-06-07
WO2001040265A3 true WO2001040265A3 (en) 2002-07-04

Family

ID=23799267

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2000/042515 WO2001040265A2 (en) 1999-12-02 2000-12-01 Ligands for a target molecule and a method for indentifying them

Country Status (5)

Country Link
EP (1) EP1237908A2 (en)
JP (1) JP2004500350A (en)
AU (1) AU4309201A (en)
CA (1) CA2392797A1 (en)
WO (1) WO2001040265A2 (en)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2003200922B8 (en) * 1997-10-06 2006-08-31 Trustees Of Tufts College Self-encoding fiber optic sensor
CA2405568A1 (en) * 2000-04-05 2001-10-18 North Carolina State University Prion-binding peptidic ligands and methods of using same
US7291456B2 (en) 2002-01-24 2007-11-06 The Regents Of The University Of California Method for determining differences in molecular interactions and for screening a combinatorial library
WO2003062831A1 (en) * 2002-01-24 2003-07-31 The Regents Of The University Of California Method for determining differences in molecular interactions and for screening a combinatorial library
WO2003066672A1 (en) * 2002-02-08 2003-08-14 Nakoshi, Hideo Peptides
AU2003231731A1 (en) 2002-04-15 2003-11-03 American National Red Cross Method for detecting ligands and targets in a mixture
US20040101830A1 (en) * 2002-07-11 2004-05-27 The American National Red Cross Method for identifying individual active entities from complex mixtures
US20050032138A1 (en) * 2003-04-14 2005-02-10 Lathrop Julia T. Method for identifying ligands specific for structural isoforms of proteins
CN101124238A (en) * 2004-12-23 2008-02-13 诺和诺德公司 Antibody binding affinity ligands
CA2591785A1 (en) 2004-12-23 2006-06-29 Novo Nordisk A/S Antibody binding affinity ligands
CN104597256B (en) * 2015-02-14 2016-05-25 河南省农业科学院 Article one, the peptide sequence and the application thereof that combine with bovine viral diarrhea virus E2 albumen
WO2023122721A2 (en) * 2021-12-22 2023-06-29 Oregon State University Peptides for cell-type specific targeting of the retina

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5516889A (en) * 1993-06-21 1996-05-14 University Technologies International, Inc. Synthetic thrombin receptor peptides
EP0742438A2 (en) * 1995-05-10 1996-11-13 Bayer Corporation Screening of combinatorial peptide libraries for selection of peptide ligand useful in affinity purification of target proteins
WO1997040861A1 (en) * 1996-04-30 1997-11-06 Immuno Aktiengesellschaft Biological material free of viral and molecular pathogens and a process for the production thereof
WO1997045743A1 (en) * 1996-05-30 1997-12-04 Helsinki University Licensing Ltd. A method for selecting target pathogen inhibiting substances and test kits for use therein
WO2000025807A1 (en) * 1998-11-05 2000-05-11 Dyax Corp. Binding moieties for human parvovirus b19

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5516889A (en) * 1993-06-21 1996-05-14 University Technologies International, Inc. Synthetic thrombin receptor peptides
EP0742438A2 (en) * 1995-05-10 1996-11-13 Bayer Corporation Screening of combinatorial peptide libraries for selection of peptide ligand useful in affinity purification of target proteins
WO1997040861A1 (en) * 1996-04-30 1997-11-06 Immuno Aktiengesellschaft Biological material free of viral and molecular pathogens and a process for the production thereof
WO1997045743A1 (en) * 1996-05-30 1997-12-04 Helsinki University Licensing Ltd. A method for selecting target pathogen inhibiting substances and test kits for use therein
WO2000025807A1 (en) * 1998-11-05 2000-05-11 Dyax Corp. Binding moieties for human parvovirus b19

Also Published As

Publication number Publication date
CA2392797A1 (en) 2001-06-07
JP2004500350A (en) 2004-01-08
WO2001040265A2 (en) 2001-06-07
AU4309201A (en) 2001-06-12
EP1237908A2 (en) 2002-09-11

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