WO2001039819A3 - Procede et dispositif permettant la recirculation en circuit ferme d'un liquide cephalo-rachidien de synthese - Google Patents

Procede et dispositif permettant la recirculation en circuit ferme d'un liquide cephalo-rachidien de synthese Download PDF

Info

Publication number
WO2001039819A3
WO2001039819A3 PCT/US2000/042473 US0042473W WO0139819A3 WO 2001039819 A3 WO2001039819 A3 WO 2001039819A3 US 0042473 W US0042473 W US 0042473W WO 0139819 A3 WO0139819 A3 WO 0139819A3
Authority
WO
WIPO (PCT)
Prior art keywords
cerebrospinal fluid
closed recirculation
csf
equipment
cassette
Prior art date
Application number
PCT/US2000/042473
Other languages
English (en)
Other versions
WO2001039819A2 (fr
Inventor
Glenn Frazer
Timothy J Pelura
Bruce Shook
Original Assignee
Neuron Therapeutics Inc
Glenn Frazer
Timothy J Pelura
Bruce Shook
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Neuron Therapeutics Inc, Glenn Frazer, Timothy J Pelura, Bruce Shook filed Critical Neuron Therapeutics Inc
Priority to AU45127/01A priority Critical patent/AU4512701A/en
Priority to EP00992584A priority patent/EP1235602A2/fr
Priority to KR1020027007066A priority patent/KR20020077351A/ko
Priority to CA002393221A priority patent/CA2393221A1/fr
Priority to JP2001541549A priority patent/JP2003515394A/ja
Publication of WO2001039819A2 publication Critical patent/WO2001039819A2/fr
Publication of WO2001039819A3 publication Critical patent/WO2001039819A3/fr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M3/00—Medical syringes, e.g. enemata; Irrigators
    • A61M3/02—Enemata; Irrigators
    • A61M3/0229—Devices operating in a closed circuit, i.e. recycling the irrigating fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M3/00—Medical syringes, e.g. enemata; Irrigators
    • A61M3/02—Enemata; Irrigators
    • A61M3/0204—Physical characteristics of the irrigation fluid, e.g. conductivity or turbidity
    • A61M3/0216—Pressure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M27/00—Drainage appliance for wounds or the like, i.e. wound drains, implanted drains
    • A61M27/002—Implant devices for drainage of body fluids from one part of the body to another
    • A61M2027/004—Implant devices for drainage of body fluids from one part of the body to another with at least a part of the circuit outside the body
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2202/00—Special media to be introduced, removed or treated
    • A61M2202/04—Liquids
    • A61M2202/0468—Liquids non-physiological
    • A61M2202/0476—Oxygenated solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/12—General characteristics of the apparatus with interchangeable cassettes forming partially or totally the fluid circuit
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/33—Controlling, regulating or measuring
    • A61M2205/3331—Pressure; Flow
    • A61M2205/3344—Measuring or controlling pressure at the body treatment site
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/36—General characteristics of the apparatus related to heating or cooling
    • A61M2205/3653—General characteristics of the apparatus related to heating or cooling by Joule effect, i.e. electric resistance
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M27/00—Drainage appliance for wounds or the like, i.e. wound drains, implanted drains
    • A61M27/002—Implant devices for drainage of body fluids from one part of the body to another
    • A61M27/006—Cerebrospinal drainage; Accessories therefor, e.g. valves
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M3/00—Medical syringes, e.g. enemata; Irrigators
    • A61M3/02—Enemata; Irrigators
    • A61M3/0201—Cassettes therefor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M3/00—Medical syringes, e.g. enemata; Irrigators
    • A61M3/02—Enemata; Irrigators
    • A61M3/0233—Enemata; Irrigators characterised by liquid supply means, e.g. from pressurised reservoirs
    • A61M3/0254—Enemata; Irrigators characterised by liquid supply means, e.g. from pressurised reservoirs the liquid being pumped
    • A61M3/0258—Enemata; Irrigators characterised by liquid supply means, e.g. from pressurised reservoirs the liquid being pumped by means of electric pumps

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biomedical Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Anesthesiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Sustainable Development (AREA)
  • Neurology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Otolaryngology (AREA)
  • External Artificial Organs (AREA)

Abstract

De manière générale, cette invention concerne des procédés et des dispositifs permettant de mettre en oeuvre une recirculation en circuit fermé de liquide céphalo-rachidien (LCR), en principe d'origine synthétique, à travers les régions cérébrales et rachidiennes du corps et l'équipement de régénération et de revitalisation. Dans une réalisation préférée présentée sous forme d'une cassette, ce dispositif comprend un ensemble modulaire de matériel jetable, arrangé de préférence d'une manière permettant une utilisation rapide et aisée en cas d'urgence. Cette cassette contient de préférence tous les composants ou la plupart des composants qui composent le circuit de liquide permettant le conditionnement du LCR thérapeutique recirculé en provenance et en direction du patient.
PCT/US2000/042473 1999-12-03 2000-12-01 Procede et dispositif permettant la recirculation en circuit ferme d'un liquide cephalo-rachidien de synthese WO2001039819A2 (fr)

Priority Applications (5)

Application Number Priority Date Filing Date Title
AU45127/01A AU4512701A (en) 1999-12-03 2000-12-01 Method and apparatus for closed recirculation of synthetic cerebrospinal fluid
EP00992584A EP1235602A2 (fr) 1999-12-03 2000-12-01 Procede et dispositif permettant la recirculation en circuit ferme d'un liquide cephalo-rachidien de synthese
KR1020027007066A KR20020077351A (ko) 1999-12-03 2000-12-01 합성 뇌척수액의 폐쇄 재순환을 위한 방법 및 기구
CA002393221A CA2393221A1 (fr) 1999-12-03 2000-12-01 Procede et dispositif permettant la recirculation en circuit ferme d'un liquide cephalo-rachidien de synthese
JP2001541549A JP2003515394A (ja) 1999-12-03 2000-12-01 合成脳脊髄液の閉鎖系再循環法および装置

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US45489399A 1999-12-03 1999-12-03
US09/454,893 1999-12-03

Publications (2)

Publication Number Publication Date
WO2001039819A2 WO2001039819A2 (fr) 2001-06-07
WO2001039819A3 true WO2001039819A3 (fr) 2002-03-14

Family

ID=23806494

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2000/042473 WO2001039819A2 (fr) 1999-12-03 2000-12-01 Procede et dispositif permettant la recirculation en circuit ferme d'un liquide cephalo-rachidien de synthese

Country Status (7)

Country Link
EP (1) EP1235602A2 (fr)
JP (1) JP2003515394A (fr)
KR (1) KR20020077351A (fr)
CN (1) CN1433328A (fr)
AU (1) AU4512701A (fr)
CA (1) CA2393221A1 (fr)
WO (1) WO2001039819A2 (fr)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6689756B2 (en) * 2001-03-02 2004-02-10 Integra Lifesciences Corporation Treatment of neurological disease
CA2411569A1 (fr) * 2002-11-12 2004-05-12 Ross E. Mantle Dispositif medical pour la recirculation extravasculaire de fluides a l'interieur de cavites corporelles dans des conditions de temperature et de pression controlees
US7004961B2 (en) * 2003-01-09 2006-02-28 Edward Wong Medical device and method for temperature control and treatment of the brain and spinal cord
CA2616037A1 (fr) 2005-07-21 2007-02-01 The Cleveland Clinic Foundation Dispositifs medicaux oscillants intracraniens et leurs utilisations
US7699799B2 (en) 2005-08-26 2010-04-20 Ceeben Systems, Inc. Ultrasonic material removal system for cardiopulmonary bypass and other applications
US20070093697A1 (en) 2005-10-21 2007-04-26 Theranova, Llc Method and apparatus for detection of right to left shunting in the cardiopulmonary vasculature
US20180311071A1 (en) * 2005-10-21 2018-11-01 Daniel R. BURNETT Method and apparatus for peritoneal oxygenation
US10569064B2 (en) 2013-03-13 2020-02-25 Minnetronix, Inc. Devices and methods for providing focal cooling to the brain and spinal cord
US10632237B2 (en) 2006-10-09 2020-04-28 Minnetronix, Inc. Tangential flow filter system for the filtration of materials from biologic fluids
US10850235B2 (en) 2006-10-09 2020-12-01 Minnetronix, Inc. Method for filtering cerebrospinal fluid (CSF) including monitoring CSF flow
ES2845146T3 (es) * 2006-10-09 2021-07-26 Neurofluidics Inc Sistema de purificación de líquido cefalorraquídeo
US10695545B2 (en) 2006-10-09 2020-06-30 Minnetronix, Inc. Systems and methods for the conditioning of cerebrospinal fluid
US8100880B2 (en) 2007-04-05 2012-01-24 Velomedix, Inc. Automated therapy system and method
US8123714B2 (en) * 2007-06-29 2012-02-28 Codman & Shurtleff, Inc. Programmable shunt with electromechanical valve actuator
JP5410423B2 (ja) 2007-07-09 2014-02-05 ベロメディックス，インク 低体温装置および方法
WO2009058353A1 (fr) 2007-11-02 2009-05-07 The Cleveland Clinic Foundation Dispositif pour augmenter le débit sanguin cérébral
WO2011114260A1 (fr) * 2010-03-19 2011-09-22 Pfizer Inc. Système de purification de liquide céphalorachidien
WO2012006625A2 (fr) 2010-07-09 2012-01-12 Velomedix, Inc. Procédé et appareil de mesure de pression
CN103706025A (zh) * 2013-12-23 2014-04-09 李桂亮 一种埋置式蛛网膜下腔微量缓释注射器
US11147540B2 (en) 2015-07-01 2021-10-19 Minnetronix, Inc. Introducer sheath and puncture tool for the introduction and placement of a catheter in tissue
ES2906952T3 (es) * 2015-08-05 2022-04-21 Minnetronix Inc Sistema de filtro de flujo tangencial para la filtración de materiales a partir de fluidos biológicos
AU2016333997B2 (en) * 2015-10-06 2019-06-06 Minnetronix, Inc. Devices and methods for providing focal cooling to the brain and spinal cord
ES2944452T3 (es) 2015-12-04 2023-06-21 Minnetronix Inc Sistemas de acondicionamiento de fluido cerebrospinal
AU2018346535A1 (en) * 2017-10-05 2020-04-30 Minnetronix, Inc. Systems, catheters, and methods for treating along the central nervous system
CN107993546B (zh) * 2018-01-16 2019-09-06 西安市红会医院 一种脑脊液循环体外模型及脑积水体外模拟方法
CN110575573B (zh) * 2019-09-24 2020-12-22 福建医科大学附属第一医院 一种用于人工脑脊液持续净化治疗的一次性管路安装系统
US11559626B2 (en) * 2020-04-08 2023-01-24 Medtronic, Inc. Means to treat Alzheimer's disease via flushing of brain parenchyma
AU2021271803A1 (en) * 2020-05-11 2022-12-08 Minnetronix Neuro, Inc. Filtering cassettes and filtering systems
JPWO2022181126A1 (fr) * 2021-02-26 2022-09-01
EP4373559A1 (fr) * 2021-07-19 2024-05-29 Enclear Therapies, Inc. Plateforme de diagnostic du liquide céphalorachidien (lcr)
GR1010335B (el) * 2022-02-11 2022-11-09 Αναστασιος Γεωργιου Τσογκας Συσκευη αποτροπης πνευμοκεφαλου

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4686085A (en) * 1980-04-14 1987-08-11 Thomas Jefferson University Stroke treatment utilizing extravascular circulation of oxygenated synthetic nutrients to treat tissue hypoxic and ischemic disorders
WO1988008728A1 (fr) * 1987-05-15 1988-11-17 The Dis Corporation Dispositif et procede de perfusion d'une tete d'animal
WO1997032621A1 (fr) * 1996-03-08 1997-09-12 Life Resuscitation Technologies, Inc. Procede et dispositif de ventilation liquide
US5716318A (en) * 1995-04-14 1998-02-10 The University Of North Carolina At Chapel Hill Method of treating cardiac arrest and apparatus for same

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4981691A (en) 1980-04-14 1991-01-01 Thomas Jefferson University Oxygenated fluorocarbon nutrient solution
US4378797A (en) 1980-04-14 1983-04-05 Thomas Jefferson University Extravascular circulation of oxygenated synthetic nutrients to treat tissue hypoxic and ischemic disorders
US5772607A (en) 1995-06-06 1998-06-30 The Nemours Foundation Body fluid collection apparatus
US5823987A (en) 1996-01-11 1998-10-20 Medtronic, Inc. Compact membrane-type blood oxygenator with concentric heat exchanger
JP3803421B2 (ja) 1996-04-26 2006-08-02 富士システムズ株式会社 気体交換装置

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4686085A (en) * 1980-04-14 1987-08-11 Thomas Jefferson University Stroke treatment utilizing extravascular circulation of oxygenated synthetic nutrients to treat tissue hypoxic and ischemic disorders
WO1988008728A1 (fr) * 1987-05-15 1988-11-17 The Dis Corporation Dispositif et procede de perfusion d'une tete d'animal
US5716318A (en) * 1995-04-14 1998-02-10 The University Of North Carolina At Chapel Hill Method of treating cardiac arrest and apparatus for same
WO1997032621A1 (fr) * 1996-03-08 1997-09-12 Life Resuscitation Technologies, Inc. Procede et dispositif de ventilation liquide

Also Published As

Publication number Publication date
CA2393221A1 (fr) 2001-06-07
CN1433328A (zh) 2003-07-30
KR20020077351A (ko) 2002-10-11
JP2003515394A (ja) 2003-05-07
AU4512701A (en) 2001-06-12
WO2001039819A2 (fr) 2001-06-07
EP1235602A2 (fr) 2002-09-04

Similar Documents

Publication Publication Date Title
WO2001039819A3 (fr) Procede et dispositif permettant la recirculation en circuit ferme d'un liquide cephalo-rachidien de synthese
HK1070258A1 (en) Improved inflatable device for use in surgical methods relating to fixation of bone
WO2005051312A3 (fr) Systeme de reduction d'agents pathogenes extracorporel
AU2001290688A1 (en) Apparatus and method for compensating for respiratory and patient motion during treatment
EP1944040A3 (fr) Procédé d'analyse pour la maladie d'Alzheimer
DE19529322C1 (de) Verpackte Beatmungsmaske
CA2308335A1 (fr) Dispositif de magnetotherapie
WO2004071612A3 (fr) Procedes et dispositifs pour traiter l'interieur d'un vaisseau sanguin
WO2000024419A8 (fr) Methodes visant a faciliter la cicatrisation d'une plaie
CA2215910A1 (fr) Gaine de catheter anti-contamination a barrieres de filtration/fermeture
WO2003005908A3 (fr) Procedes et dispositifs permettant de naviguer dans l'espace sous-arachnoidien
EP0558031A3 (en) Apparatus and method for subcuticular stapling of body tissue
EP2255743A3 (fr) Systéme à champ ouvert servant à la chirurgie magnétique
WO2004034875A3 (fr) Appareil du type gaine pour dispositif medical et son procede de fabrication et d'utilisation
WO2004036377A3 (fr) Configuration et controle des parametres de traitement therapeutique d'un systeme de dispositif medical
IL151563A0 (en) A longitudinal compression apparatus for compressing tissue
SE9801427D0 (sv) Förfarande för bestämning av minst en parameter samt en andningsapparat
IL114352A0 (en) Catheter
WO2003069332A3 (fr) Detection et/ou surveillance de maladies liees a la synucleine
EP1455778A4 (fr) Procedes de traitement de malaises neurovasculaires peripheriques
CA2382143A1 (fr) Procede, reactif et cartouche d'essai destines a determiner le temps de coagulation
EP1295604A4 (fr) Preventifs et remedes contre des maladies associees a la demyelinisation
US20090226492A1 (en) Use of an activated zeolite as a pharmaceutical agent for reducing toxic substances
WO2002055071A8 (fr) Compositions et methodes de regulation du taux de lipoproteines et de l'hypercholesterolemie au moyen de limonoides, de flavonoides et de tocotrienols
AU2002364442A1 (en) Method for regulating the titer of a solution, device for controlling said regulation and system comprising such a device

Legal Events

Date Code Title Description
AK Designated states

Kind code of ref document: A2

Designated state(s): AE AG AL AM AT AU AZ BA BB BG BR BY BZ CA CH CN CR CU CZ DE DK DM DZ EE ES FI GB GD GE GH GM HR HU ID IL IN IS JP KE KG KP KR KZ LC LK LR LS LT LU LV MA MD MG MK MN MW MX MZ NO NZ PL PT RO RU SD SE SG SI SK SL TJ TM TR TT TZ UA UG US UZ VN YU ZA ZW

AL Designated countries for regional patents

Kind code of ref document: A2

Designated state(s): GH GM KE LS MW MZ SD SL SZ TZ UG ZW AM AZ BY KG KZ MD RU TJ TM AT BE CH CY DE DK ES FI FR GB GR IE IT LU MC NL PT SE TR BF BJ CF CG CI CM GA GN GW ML MR NE SN TD TG

121 Ep: the epo has been informed by wipo that ep was designated in this application
DFPE Request for preliminary examination filed prior to expiration of 19th month from priority date (pct application filed before 20040101)
AK Designated states

Kind code of ref document: A3

Designated state(s): AE AG AL AM AT AU AZ BA BB BG BR BY BZ CA CH CN CR CU CZ DE DK DM DZ EE ES FI GB GD GE GH GM HR HU ID IL IN IS JP KE KG KP KR KZ LC LK LR LS LT LU LV MA MD MG MK MN MW MX MZ NO NZ PL PT RO RU SD SE SG SI SK SL TJ TM TR TT TZ UA UG US UZ VN YU ZA ZW

AL Designated countries for regional patents

Kind code of ref document: A3

Designated state(s): GH GM KE LS MW MZ SD SL SZ TZ UG ZW AM AZ BY KG KZ MD RU TJ TM AT BE CH CY DE DK ES FI FR GB GR IE IT LU MC NL PT SE TR BF BJ CF CG CI CM GA GN GW ML MR NE SN TD TG

WWE Wipo information: entry into national phase

Ref document number: 1020027007066

Country of ref document: KR

ENP Entry into the national phase

Ref country code: JP

Ref document number: 2001 541549

Kind code of ref document: A

Format of ref document f/p: F

WWE Wipo information: entry into national phase

Ref document number: 2393221

Country of ref document: CA

WWE Wipo information: entry into national phase

Ref document number: 2000992584

Country of ref document: EP

WWE Wipo information: entry into national phase

Ref document number: 008187541

Country of ref document: CN

WWP Wipo information: published in national office

Ref document number: 2000992584

Country of ref document: EP

WWP Wipo information: published in national office

Ref document number: 1020027007066

Country of ref document: KR

REG Reference to national code

Ref country code: DE

Ref legal event code: 8642

WWW Wipo information: withdrawn in national office

Ref document number: 2000992584

Country of ref document: EP