WO2001038505A3 - Secreted protein, zalpha37 - Google Patents

Secreted protein, zalpha37 Download PDF

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Publication number
WO2001038505A3
WO2001038505A3 PCT/US2000/032073 US0032073W WO0138505A3 WO 2001038505 A3 WO2001038505 A3 WO 2001038505A3 US 0032073 W US0032073 W US 0032073W WO 0138505 A3 WO0138505 A3 WO 0138505A3
Authority
WO
WIPO (PCT)
Prior art keywords
polypeptides
methods
antibodies
zalpha37
secreted protein
Prior art date
Application number
PCT/US2000/032073
Other languages
French (fr)
Other versions
WO2001038505A2 (en
Inventor
David A Adler
Dennis L Dong
Sarah Pownder
Zeren Gao
Darrell C Conklin
Original Assignee
Zymogenetics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Zymogenetics Inc filed Critical Zymogenetics Inc
Priority to AU19256/01A priority Critical patent/AU1925601A/en
Publication of WO2001038505A2 publication Critical patent/WO2001038505A2/en
Publication of WO2001038505A3 publication Critical patent/WO2001038505A3/en

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/1048—Glycosyltransferases (2.4)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide

Abstract

Novel soluble, membrane bound, and cytosolic UDP-glycosyltransferase enzyme polypeptides, polynucleotides encoding the polypeptides, antibodies and related compositions and methods are disclosed. The polypeptides may be used for detecting substrates, agonists and antagonists. The polypeptides, polynucleotides and antibodies may also be used in methods that modulate cell-cell interactions, and glycoprotein biosynthesis and glycolipid metabolism, and growth factor and hormone regulation, as well as methods of detection and diagnosis of disease.
PCT/US2000/032073 1999-11-23 2000-11-22 Secreted protein, zalpha37 WO2001038505A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU19256/01A AU1925601A (en) 1999-11-23 2000-11-22 Secreted protein, zalpha37

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US44799899A 1999-11-23 1999-11-23
US09/447,998 1999-11-23
US50593200A 2000-02-14 2000-02-14
US09/505,932 2000-02-14

Publications (2)

Publication Number Publication Date
WO2001038505A2 WO2001038505A2 (en) 2001-05-31
WO2001038505A3 true WO2001038505A3 (en) 2001-11-22

Family

ID=27035192

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2000/032073 WO2001038505A2 (en) 1999-11-23 2000-11-22 Secreted protein, zalpha37

Country Status (2)

Country Link
AU (1) AU1925601A (en)
WO (1) WO2001038505A2 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002002774A2 (en) * 2000-06-30 2002-01-10 Millennium Pharmaceuticals, Inc. 32626, a human udp-glycosyltransferase and uses thereof

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000012708A2 (en) * 1998-09-01 2000-03-09 Genentech, Inc. Further pro polypeptides and sequences thereof
EP1067182A2 (en) * 1999-07-08 2001-01-10 Helix Research Institute Secretory protein or membrane protein

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000012708A2 (en) * 1998-09-01 2000-03-09 Genentech, Inc. Further pro polypeptides and sequences thereof
EP1067182A2 (en) * 1999-07-08 2001-01-10 Helix Research Institute Secretory protein or membrane protein

Non-Patent Citations (10)

* Cited by examiner, † Cited by third party
Title
AMADO M ET AL: "A Family of human beta3-Galactosyltransferases (subtitle: characterization of four members of a udp-galactose:BETA-n-acetyl-glu cosamine/BETA-nacetyl-galactosamine BETA-1,3- galactosyltransferase family", JOURNAL OF BIOLOGICAL CHEMISTRY,US,AMERICAN SOCIETY OF BIOLOGICAL CHEMISTS, BALTIMORE, MD, vol. 273, no. 21, 22 May 1998 (1998-05-22), pages 12770 - 12778, XP002109786, ISSN: 0021-9258 *
DATABASE GENBANK 13 August 1998 (1998-08-13), "ov51a05.s1 Soares_testis_NHT Homo sapiens cDNA clone, similar to rabbit UDP-glucuronyltransferase 2A2 microsomal", XP002164511 *
DATABASE GENBANK 16 November 1999 (1999-11-16), "xj82g11.x1 Soares_NFL_T_GBC_S1 Homo sapiens cDNA clone, similar to rat 2-hydroxyacylsphingosine 1-beta-Galactosyltransferase", XP002164509 *
DATABASE GENBANK 17 March 1999 (1999-03-17), MARRA M. ET AL.: "uj39b11.y1 Sugano mouse kidney mkia Mus musculus cDNA clone. Similar to 2-hydroxyacyl1-beta-Galactosyltansferase precursor.", XP002164508 *
DATABASE GENBANK 17 March 1999 (1999-03-17), MARRA M. ET AL.: "uj39e10.y1 Sugano mouse kidney mkia Mus musculus cDNA clone. Similar to 2-Hydroxyacylsphingosine 1-beta-Galactosyltransferase precursor.", XP002164507 *
DATABASE GENBANK 2 July 1999 (1999-07-02), MARRA M. ET AL.: "uj31b07.y1 Sugano mouse kidney mkia Mus musculus cDNA clone. Similar to UDP-Glucoronyltransferase.", XP002164505 *
DATABASE GENBANK 2 June 1999 (1999-06-02), "wd45g04.x1 Soares_NFL_T_S1 Homo sapiens cDNA clone, similar to mouse 2-hydroxyacylsphingosine 1-beta-galactosyltransferase precursor", XP002164510 *
DATABASE GENBANK 20 May 1998 (1998-05-20), "op64h06.s1 Soares_NFL_T_GBC_S1 Homo sapiens cDNA clone, similar to rabbit UDP-Glucuronyltransferase 2A2 microsomal.", XP002164512 *
DATABASE GENBANK 21 July 1999 (1999-07-21), MARRA M. ET AL.: "uj36h03.y1 Sugano mouse kidney mkia Mus musculus cDNA clone. Similar to UDP-Glucoronyltransferase.", XP002164506 *
HENNET T ET AL: "Genomic cloning and expression of three murine UDP-galactose:betaGlcNAc beta1,3-galactosyltransferase genes", JOURNAL OF BIOLOGICAL CHEMISTRY,US,AMERICAN SOCIETY OF BIOLOGICAL CHEMISTS, BALTIMORE, MD, vol. 273, no. 1, 2 January 1998 (1998-01-02), pages 58 - 65, XP002109783, ISSN: 0021-9258 *

Also Published As

Publication number Publication date
WO2001038505A2 (en) 2001-05-31
AU1925601A (en) 2001-06-04

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