WO2001035979A3 - Combined pde3 and pde4 inhibitor therapy for the treatment of obesity - Google Patents
Combined pde3 and pde4 inhibitor therapy for the treatment of obesity Download PDFInfo
- Publication number
- WO2001035979A3 WO2001035979A3 PCT/US2000/042137 US0042137W WO0135979A3 WO 2001035979 A3 WO2001035979 A3 WO 2001035979A3 US 0042137 W US0042137 W US 0042137W WO 0135979 A3 WO0135979 A3 WO 0135979A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- obesity
- treatment
- pde4 inhibitor
- inhibitor therapy
- pde3
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
Landscapes
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Diabetes (AREA)
- Child & Adolescent Psychology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
AU32703/01A AU3270301A (en) | 1999-11-13 | 2000-11-13 | Combined pde3 and pde4 inhibitor therapy for the treatment of obesity |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US16541899P | 1999-11-13 | 1999-11-13 | |
US60/165,418 | 1999-11-13 |
Publications (2)
Publication Number | Publication Date |
---|---|
WO2001035979A2 WO2001035979A2 (en) | 2001-05-25 |
WO2001035979A3 true WO2001035979A3 (en) | 2002-01-03 |
Family
ID=22598815
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/US2000/042137 WO2001035979A2 (en) | 1999-11-13 | 2000-11-13 | Combined pde3 and pde4 inhibitor therapy for the treatment of obesity |
Country Status (2)
Country | Link |
---|---|
AU (1) | AU3270301A (en) |
WO (1) | WO2001035979A2 (en) |
Families Citing this family (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2002051502A1 (en) * | 2000-12-22 | 2002-07-04 | The Government Of The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Combined inhibition of phosphodiesterase-4 (pde-4) and phosphodiesterase-3 (pde-3) as a therapy for th1-mediated autoimmune diseases |
AU2002312543A1 (en) * | 2001-08-01 | 2003-02-17 | University Of Utah, Technology Transfer Office | Isoform-selective inhibitors and activators of pde3 cyclic |
FR2849594B1 (en) * | 2003-01-03 | 2006-10-27 | Oreal | USE OF ZARDAVERINE AS SLIMMING |
JP2007504201A (en) | 2003-09-05 | 2007-03-01 | アルタナ ファルマ アクチエンゲゼルシャフト | Use of PDE4 inhibitors for the treatment of diabetes mellitus |
US8017633B2 (en) | 2005-03-08 | 2011-09-13 | Nycomed Gmbh | Roflumilast for the treatment of diabetes mellitus |
US20100179131A1 (en) * | 2006-09-07 | 2010-07-15 | Nycomed Gmbh | Combination treatment for diabetes mellitus |
JPWO2009154230A1 (en) * | 2008-06-17 | 2011-12-01 | 持田製薬株式会社 | Non-alcoholic steatohepatitis prevention / improvement / treatment drug |
JP5842254B2 (en) * | 2010-06-23 | 2016-01-13 | 国立大学法人九州大学 | Combination of EGCG or methylated EGCG and PDE inhibitor |
US20150359798A1 (en) * | 2011-09-06 | 2015-12-17 | Jansfat Biotechnology Co., Ltd. | Piperazinyl derivative reduces high-fat diet-induced accumulation of fat in the livers, therapeutically |
CA3026083C (en) * | 2016-06-03 | 2024-04-02 | The Trustees Of Columbia University In The City Of New York | Methods of treating prader-willi syndrome |
Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1999014239A1 (en) * | 1997-09-12 | 1999-03-25 | Wolf Georg Forssmann | Composition for treating diabetes mellitus and obesity |
-
2000
- 2000-11-13 WO PCT/US2000/042137 patent/WO2001035979A2/en active Application Filing
- 2000-11-13 AU AU32703/01A patent/AU3270301A/en not_active Abandoned
Patent Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1999014239A1 (en) * | 1997-09-12 | 1999-03-25 | Wolf Georg Forssmann | Composition for treating diabetes mellitus and obesity |
Non-Patent Citations (3)
Title |
---|
DOUSA M K ET AL: "Antagonists of cyclic nucleotide phosphodiesterase (PDE) isozymes PDE 3 and PDE 4 suppress lymphoblastic response to HLA class II alloantigens: a potential novel approach to preventing allograft rejection?.", CLINICAL NEPHROLOGY, (1997 MAR) 47 (3) 187-9., XP002168562 * |
PAN X ET AL: "Synergistic interactions between selective pharmacological inhibitors of phosphodiesterase isozyme families PDE III and PDE IV to attenuate proliferation of rat vascular smooth muscle cells.", BIOCHEMICAL PHARMACOLOGY, (1994 AUG 17) 48 (4) 827-35., XP002168561 * |
SCHMITZ-PEIFFER C ET AL: "Characterization of the cyclic nucleotide phosphodiesterase isoenzymes present in rat epididymal fat cells.", CELLULAR SIGNALLING, (1992 JAN) 4 (1) 37-49., XP002168563 * |
Also Published As
Publication number | Publication date |
---|---|
AU3270301A (en) | 2001-05-30 |
WO2001035979A2 (en) | 2001-05-25 |
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