WO2001034795A3 - Casb7435 polypeptide, nucleic acid encoding it, and their uses in treatment and diagnosis - Google Patents

Casb7435 polypeptide, nucleic acid encoding it, and their uses in treatment and diagnosis Download PDF

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Publication number
WO2001034795A3
WO2001034795A3 PCT/EP2000/011035 EP0011035W WO0134795A3 WO 2001034795 A3 WO2001034795 A3 WO 2001034795A3 EP 0011035 W EP0011035 W EP 0011035W WO 0134795 A3 WO0134795 A3 WO 0134795A3
Authority
WO
WIPO (PCT)
Prior art keywords
casb7435
polypeptide
diagnosis
treatment
nucleic acid
Prior art date
Application number
PCT/EP2000/011035
Other languages
French (fr)
Other versions
WO2001034795A2 (en
Inventor
Y De Bassols Carlota Vinals
Thierry Coche
Jean-Pol Cassart
Swann Roman Jean-Thomas Gaulis
Original Assignee
Smithkline Beecham Biolog
Y De Bassols Carlota Vinals
Thierry Coche
Cassart Jean Pol
Gaulis Swann Roman Jean Thomas
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smithkline Beecham Biolog, Y De Bassols Carlota Vinals, Thierry Coche, Cassart Jean Pol, Gaulis Swann Roman Jean Thomas filed Critical Smithkline Beecham Biolog
Priority to AU15199/01A priority Critical patent/AU1519901A/en
Publication of WO2001034795A2 publication Critical patent/WO2001034795A2/en
Publication of WO2001034795A3 publication Critical patent/WO2001034795A3/en

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/1048—Glycosyltransferases (2.4)
    • C12N9/1051—Hexosyltransferases (2.4.1)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/46—Cellular immunotherapy
    • A61K39/461—Cellular immunotherapy characterised by the cell type used
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/46—Cellular immunotherapy
    • A61K39/462—Cellular immunotherapy characterized by the effect or the function of the cells
    • A61K39/4622—Antigen presenting cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/46—Cellular immunotherapy
    • A61K39/464—Cellular immunotherapy characterised by the antigen targeted or presented
    • A61K39/4643—Vertebrate antigens
    • A61K39/4644—Cancer antigens
    • A61K39/464499—Undefined tumor antigens, e.g. tumor lysate or antigens targeted by cells isolated from tumor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/52—Bacterial cells; Fungal cells; Protozoal cells
    • A61K2039/523—Bacterial cells; Fungal cells; Protozoal cells expressing foreign proteins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/53—DNA (RNA) vaccination
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/30—Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Cell Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Mycology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Immunology (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Oncology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

CASB7435 polypeptides and polynucleotides and methods for producing such polypeptides by recombinant techniques are disclosed. Also disclosed are methods for utilizing CASB7435 polypeptides and polynucleotides in diagnostics, and vaccines for prophylactic and therapeutic treatment of cancers, particularly ovarian and colon cancers, autoimmune diseases, and related conditions.
PCT/EP2000/011035 1999-11-09 2000-11-08 Casb7435 polypeptide, nucleic acid encoding it, and their uses in treatment and diagnosis WO2001034795A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU15199/01A AU1519901A (en) 1999-11-09 2000-11-08 Novel compounds

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB9926532.4 1999-11-09
GBGB9926532.4A GB9926532D0 (en) 1999-11-09 1999-11-09 Novel compounds

Publications (2)

Publication Number Publication Date
WO2001034795A2 WO2001034795A2 (en) 2001-05-17
WO2001034795A3 true WO2001034795A3 (en) 2002-01-24

Family

ID=10864233

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP2000/011035 WO2001034795A2 (en) 1999-11-09 2000-11-08 Casb7435 polypeptide, nucleic acid encoding it, and their uses in treatment and diagnosis

Country Status (3)

Country Link
AU (1) AU1519901A (en)
GB (1) GB9926532D0 (en)
WO (1) WO2001034795A2 (en)

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999063088A2 (en) * 1998-06-02 1999-12-09 Genentech, Inc. Membrane-bound proteins and nucleic acids encoding the same

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999063088A2 (en) * 1998-06-02 1999-12-09 Genentech, Inc. Membrane-bound proteins and nucleic acids encoding the same

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
LEE YOUNG-CHOON ET AL: "Molecular cloning and functional expression of two members of mouse NeuAcalpha2,3Galbeta1,3GalNAc GalNAcalpha2,6-sialyltransferase family, ST6GalNAc III and IV.", JOURNAL OF BIOLOGICAL CHEMISTRY, vol. 274, no. 17, 23 April 1999 (1999-04-23), pages 11958 - 11967, XP002173868, ISSN: 0021-9258 *

Also Published As

Publication number Publication date
AU1519901A (en) 2001-06-06
GB9926532D0 (en) 2000-01-12
WO2001034795A2 (en) 2001-05-17

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