WO2000043509A3 - Polynucleotides and their applications in diagnostics - Google Patents

Polynucleotides and their applications in diagnostics Download PDF

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Publication number
WO2000043509A3
WO2000043509A3 PCT/EP2000/000346 EP0000346W WO0043509A3 WO 2000043509 A3 WO2000043509 A3 WO 2000043509A3 EP 0000346 W EP0000346 W EP 0000346W WO 0043509 A3 WO0043509 A3 WO 0043509A3
Authority
WO
WIPO (PCT)
Prior art keywords
polynucleotides
diagnostics
polypeptides
applications
casb611
Prior art date
Application number
PCT/EP2000/000346
Other languages
French (fr)
Other versions
WO2000043509A2 (en
Inventor
Carlota Vinals-Bassols
Original Assignee
Smithkline Beecham Biolog
Vinals Bassols Carlota
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB9901078.7A external-priority patent/GB9901078D0/en
Priority claimed from GBGB9902090.1A external-priority patent/GB9902090D0/en
Priority claimed from GBGB9902168.5A external-priority patent/GB9902168D0/en
Priority claimed from GBGB9902163.6A external-priority patent/GB9902163D0/en
Priority claimed from GBGB9902169.3A external-priority patent/GB9902169D0/en
Priority claimed from GBGB9907901.4A external-priority patent/GB9907901D0/en
Priority to CA002358697A priority Critical patent/CA2358697A1/en
Priority to AU22924/00A priority patent/AU2292400A/en
Application filed by Smithkline Beecham Biolog, Vinals Bassols Carlota filed Critical Smithkline Beecham Biolog
Priority to JP2000594917A priority patent/JP2002534977A/en
Priority to EP00901580A priority patent/EP1144622A2/en
Publication of WO2000043509A2 publication Critical patent/WO2000043509A2/en
Publication of WO2000043509A3 publication Critical patent/WO2000043509A3/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4748—Tumour specific antigens; Tumour rejection antigen precursors [TRAP], e.g. MAGE
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6809—Methods for determination or identification of nucleic acids involving differential detection
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/136—Screening for pharmacological compounds

Abstract

CASB611, CASB500, CASB501, CASB502, CASB505, or CASB507 polypeptides and polynucleotides and methods for producing such polypeptides by recombinant techniques are disclosed. Also disclosed are methods for utilizing CASB611, CASB500, CASB501, CASB502, CASB505, or CASB507 polypeptides and polynucleotides in diagnostics, and vaccines for prophylactic and therapeutic treatment of cancers, particularly colon cancers, autoimmune diseases, and related conditions.
PCT/EP2000/000346 1999-01-19 2000-01-17 Polynucleotides and their applications in diagnostics WO2000043509A2 (en)

Priority Applications (4)

Application Number Priority Date Filing Date Title
EP00901580A EP1144622A2 (en) 1999-01-19 2000-01-17 Polynucleotides and their application in diagnostics
JP2000594917A JP2002534977A (en) 1999-01-19 2000-01-17 New compound
CA002358697A CA2358697A1 (en) 1999-01-19 2000-01-17 Polynucleotides and their applications in diagnostics
AU22924/00A AU2292400A (en) 1999-01-19 2000-01-17 Novel compounds

Applications Claiming Priority (12)

Application Number Priority Date Filing Date Title
GBGB9901078.7A GB9901078D0 (en) 1999-01-19 1999-01-19 Novel compounds
GB9901078.7 1999-01-19
GBGB9902090.1A GB9902090D0 (en) 1999-01-29 1999-01-29 Novel compounds
GB9902090.1 1999-01-29
GBGB9902169.3A GB9902169D0 (en) 1999-02-01 1999-02-01 Novel compounds
GBGB9902163.6A GB9902163D0 (en) 1999-02-01 1999-02-01 Novel compounds
GB9902169.3 1999-02-01
GB9902163.6 1999-02-01
GBGB9902168.5A GB9902168D0 (en) 1999-02-01 1999-02-01 Novel compounds
GB9902168.5 1999-02-01
GBGB9907901.4A GB9907901D0 (en) 1999-04-07 1999-04-07 Novel compounds
GB9907901.4 1999-04-07

Publications (2)

Publication Number Publication Date
WO2000043509A2 WO2000043509A2 (en) 2000-07-27
WO2000043509A3 true WO2000043509A3 (en) 2000-11-02

Family

ID=27547331

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP2000/000346 WO2000043509A2 (en) 1999-01-19 2000-01-17 Polynucleotides and their applications in diagnostics

Country Status (5)

Country Link
EP (1) EP1144622A2 (en)
JP (1) JP2002534977A (en)
AU (1) AU2292400A (en)
CA (1) CA2358697A1 (en)
WO (1) WO2000043509A2 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1294871A1 (en) * 2000-06-21 2003-03-26 Amgen, Inc. Secreted epithelial colon stromal-1 polypeptides, nucleic acids encoding the same and uses thereof

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1995015381A2 (en) * 1993-12-02 1995-06-08 The Johns Hopkins University HUMAN MUTATOR GENE hMSH2 AND HEREDITARY NON POLYPOSIS COLORECTAL CANCER
WO1997033903A1 (en) * 1996-03-11 1997-09-18 Human Genome Sciences, Inc. HUMAN MutY
WO1998053319A2 (en) * 1997-05-21 1998-11-26 The Johns Hopkins University Gene expression profiles in normal and cancer cells

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1995015381A2 (en) * 1993-12-02 1995-06-08 The Johns Hopkins University HUMAN MUTATOR GENE hMSH2 AND HEREDITARY NON POLYPOSIS COLORECTAL CANCER
WO1997033903A1 (en) * 1996-03-11 1997-09-18 Human Genome Sciences, Inc. HUMAN MutY
WO1998053319A2 (en) * 1997-05-21 1998-11-26 The Johns Hopkins University Gene expression profiles in normal and cancer cells

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
Nucleotide Sequence Database EMBL ID AA587764, Accession number AA587764 18 september 1997 99.3% identity with Seq.ID:1 nt.1-441 *
Nucleotide Sequence Database EMBL ID AI339648, Accession number AI339648 31 december 1998 100% identity with Seq.ID:1 nt.6-411 *
Nucleotide Sequence Database EMBL ID HS1220328, Accession number AA422178 19 may 1997 99.8% identity with Seq.ID:1 nt.281-784 reverse orientation *

Also Published As

Publication number Publication date
JP2002534977A (en) 2002-10-22
EP1144622A2 (en) 2001-10-17
WO2000043509A2 (en) 2000-07-27
AU2292400A (en) 2000-08-07
CA2358697A1 (en) 2000-07-27

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