WO2001034794A1 - Antigene surexprime dans le cancer du colon (casb7434) - Google Patents

Antigene surexprime dans le cancer du colon (casb7434) Download PDF

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Publication number
WO2001034794A1
WO2001034794A1 PCT/EP2000/010979 EP0010979W WO0134794A1 WO 2001034794 A1 WO2001034794 A1 WO 2001034794A1 EP 0010979 W EP0010979 W EP 0010979W WO 0134794 A1 WO0134794 A1 WO 0134794A1
Authority
WO
WIPO (PCT)
Prior art keywords
polypeptide
seq
polynucleotide
cells
identity
Prior art date
Application number
PCT/EP2000/010979
Other languages
English (en)
Inventor
Jean-Pol Cassart
Thierry Coche
Carlota Vinals Y De Bassols
Swann Roman Jean-Thomas Gaulis
Original Assignee
Smithkline Beecham Biologicals S.A.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB9926636.3A external-priority patent/GB9926636D0/en
Priority claimed from GB0008809A external-priority patent/GB0008809D0/en
Priority claimed from GB0012703A external-priority patent/GB0012703D0/en
Application filed by Smithkline Beecham Biologicals S.A. filed Critical Smithkline Beecham Biologicals S.A.
Priority to AU13928/01A priority Critical patent/AU1392801A/en
Publication of WO2001034794A1 publication Critical patent/WO2001034794A1/fr

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57407—Specifically defined cancers
    • G01N33/57446—Specifically defined cancers of stomach or intestine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/46—Cellular immunotherapy
    • A61K39/461—Cellular immunotherapy characterised by the cell type used
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/46—Cellular immunotherapy
    • A61K39/462—Cellular immunotherapy characterized by the effect or the function of the cells
    • A61K39/4622—Antigen presenting cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/46—Cellular immunotherapy
    • A61K39/464—Cellular immunotherapy characterised by the antigen targeted or presented
    • A61K39/4643—Vertebrate antigens
    • A61K39/4644—Cancer antigens
    • A61K39/464499—Undefined tumor antigens, e.g. tumor lysate or antigens targeted by cells isolated from tumor
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4748—Tumour specific antigens; Tumour rejection antigen precursors [TRAP], e.g. MAGE
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/52—Bacterial cells; Fungal cells; Protozoal cells
    • A61K2039/523—Bacterial cells; Fungal cells; Protozoal cells expressing foreign proteins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/136—Screening for pharmacological compounds

Abstract

L'invention concerne des polypeptides et des polynucléotides de CASB7434 et des procédés de préparation de ces polypeptides au moyen de techniques de recombinaison. L'invention concerne également des procédés d'utilisation de ces polypeptides et de ces polynucléotides de CASB7434 dans les diagnostiques, et dans les vaccins pour le traitement thérapeutique de cancers, notamment les cancers de l'ovaire et du colon, de maladies auto-immunes, et d'états pathologiques voisins.
PCT/EP2000/010979 1999-11-10 2000-11-06 Antigene surexprime dans le cancer du colon (casb7434) WO2001034794A1 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU13928/01A AU1392801A (en) 1999-11-10 2000-11-06 Casb7434, an antigen over-expressed in colon cancer

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
GB9926636.3 1999-11-10
GBGB9926636.3A GB9926636D0 (en) 1999-11-11 1999-11-11 Novel compounds
GB0008809.6 2000-04-10
GB0008809A GB0008809D0 (en) 2000-04-10 2000-04-10 Novel compounds
GB0012703.5 2000-05-24
GB0012703A GB0012703D0 (en) 2000-05-24 2000-05-24 Novel compounds

Publications (1)

Publication Number Publication Date
WO2001034794A1 true WO2001034794A1 (fr) 2001-05-17

Family

ID=27255661

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP2000/010979 WO2001034794A1 (fr) 1999-11-10 2000-11-06 Antigene surexprime dans le cancer du colon (casb7434)

Country Status (2)

Country Link
AU (1) AU1392801A (fr)
WO (1) WO2001034794A1 (fr)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001090129A2 (fr) * 2000-05-19 2001-11-29 Corixa Corporation Traitement prophylactique et therapeutique de maladies infectieuses et autres avec des composes a base de mono- et disaccharides
WO2006114478A1 (fr) * 2005-04-26 2006-11-02 Karyon-Ctt Ltd Agents diagnostiques et therapeutiques
US7902159B2 (en) 2000-05-19 2011-03-08 Corixa Corporation Prophylactic and therapeutic treatment of infectious and other diseases with mono- and disaccharide-based compounds

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999002546A1 (fr) * 1997-07-08 1999-01-21 Human Genome Sciences, Inc. 123 proteines humaines secretees
WO1999049030A1 (fr) * 1998-03-20 1999-09-30 Smithkline Beecham Biologicals S.A. Compose apparente a pap-1

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999002546A1 (fr) * 1997-07-08 1999-01-21 Human Genome Sciences, Inc. 123 proteines humaines secretees
WO1999049030A1 (fr) * 1998-03-20 1999-09-30 Smithkline Beecham Biologicals S.A. Compose apparente a pap-1

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
DATABASE EMEST_HUM6 EMBL Heidelberg, Germany; 27 May 1999 (1999-05-27), NCI-CGAP: "Homo sapiens cDNA clone IMAGE:2275554", XP002160110 *

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001090129A2 (fr) * 2000-05-19 2001-11-29 Corixa Corporation Traitement prophylactique et therapeutique de maladies infectieuses et autres avec des composes a base de mono- et disaccharides
WO2001090129A3 (fr) * 2000-05-19 2002-06-06 Corixa Corp Traitement prophylactique et therapeutique de maladies infectieuses et autres avec des composes a base de mono- et disaccharides
US6800613B2 (en) 2000-05-19 2004-10-05 Corixa Corporation Prophylactic and therapeutic treatment of infectious and other diseases with mono- and disaccharide-based compounds
US7902159B2 (en) 2000-05-19 2011-03-08 Corixa Corporation Prophylactic and therapeutic treatment of infectious and other diseases with mono- and disaccharide-based compounds
US8318697B2 (en) 2000-05-19 2012-11-27 Corixa Corporation Prophylactic and therapeutic treatment of infectious and other diseases with mono- and disaccharide-based compounds
WO2006114478A1 (fr) * 2005-04-26 2006-11-02 Karyon-Ctt Ltd Agents diagnostiques et therapeutiques

Also Published As

Publication number Publication date
AU1392801A (en) 2001-06-06

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