WO2001032201A3 - A pharmaceutical composition having high cell membrane permeability - Google Patents

A pharmaceutical composition having high cell membrane permeability Download PDF

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Publication number
WO2001032201A3
WO2001032201A3 PCT/US2000/026257 US0026257W WO0132201A3 WO 2001032201 A3 WO2001032201 A3 WO 2001032201A3 US 0026257 W US0026257 W US 0026257W WO 0132201 A3 WO0132201 A3 WO 0132201A3
Authority
WO
WIPO (PCT)
Prior art keywords
pharmaceutical composition
cell membrane
membrane permeability
high cell
permeability
Prior art date
Application number
PCT/US2000/026257
Other languages
French (fr)
Other versions
WO2001032201A2 (en
Inventor
Michael Terrence Kuhfeld
Ovidio Vargas
Original Assignee
Lilly Co Eli
Michael Terrence Kuhfeld
Ovidio Vargas
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli, Michael Terrence Kuhfeld, Ovidio Vargas filed Critical Lilly Co Eli
Priority to AU11893/01A priority Critical patent/AU1189301A/en
Publication of WO2001032201A2 publication Critical patent/WO2001032201A2/en
Publication of WO2001032201A3 publication Critical patent/WO2001032201A3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/29—Parathyroid hormone, i.e. parathormone; Parathyroid hormone-related peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A61K47/183—Amino acids, e.g. glycine, EDTA or aspartame
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Endocrinology (AREA)
  • Dermatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicinal Preparation (AREA)

Abstract

A pharmaceutical composition useful for increasing the cell membrane permeability of PTH.
PCT/US2000/026257 1999-10-29 2000-10-16 A pharmaceutical composition having high cell membrane permeability WO2001032201A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU11893/01A AU1189301A (en) 1999-10-29 2000-10-16 A pharmaceutical composition having high cell membrane permeability

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US16255799P 1999-10-29 1999-10-29
US60/162,557 1999-10-29

Publications (2)

Publication Number Publication Date
WO2001032201A2 WO2001032201A2 (en) 2001-05-10
WO2001032201A3 true WO2001032201A3 (en) 2001-09-27

Family

ID=22586144

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2000/026257 WO2001032201A2 (en) 1999-10-29 2000-10-16 A pharmaceutical composition having high cell membrane permeability

Country Status (3)

Country Link
AU (1) AU1189301A (en)
PE (1) PE20010825A1 (en)
WO (1) WO2001032201A2 (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BRPI0209748B1 (en) 2001-06-01 2015-11-24 Novartis Ag pharmaceutical composition for oral administration comprising parathyroid hormone (pth), and its use
CA2782640A1 (en) 2009-12-07 2011-06-16 Michigan Technological University Black bear parathyroid hormone and methods of using black bear parathyroid hormone
CN118001411A (en) * 2024-04-09 2024-05-10 深圳奥礼生物科技有限公司 Intestinal tract absorption composition

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1996019197A1 (en) * 1994-12-22 1996-06-27 Astra Aktiebolag Aerosol formulations of peptides and proteins
WO1997014429A1 (en) * 1995-10-17 1997-04-24 Boehringer Mannheim Gmbh Stable pharmaceutical forms of administration containing parathormone
EP0845265A1 (en) * 1995-08-15 1998-06-03 Asahi Kasei Kogyo Kabushiki Kaisha Mucosal preparation containing physiologically active peptide

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1996019197A1 (en) * 1994-12-22 1996-06-27 Astra Aktiebolag Aerosol formulations of peptides and proteins
EP0845265A1 (en) * 1995-08-15 1998-06-03 Asahi Kasei Kogyo Kabushiki Kaisha Mucosal preparation containing physiologically active peptide
WO1997014429A1 (en) * 1995-10-17 1997-04-24 Boehringer Mannheim Gmbh Stable pharmaceutical forms of administration containing parathormone

Also Published As

Publication number Publication date
PE20010825A1 (en) 2001-08-13
AU1189301A (en) 2001-05-14
WO2001032201A2 (en) 2001-05-10

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WO2001032201A3 (en) A pharmaceutical composition having high cell membrane permeability

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