WO2001024784A3 - New use - Google Patents
New use Download PDFInfo
- Publication number
- WO2001024784A3 WO2001024784A3 PCT/JP2000/006874 JP0006874W WO0124784A3 WO 2001024784 A3 WO2001024784 A3 WO 2001024784A3 JP 0006874 W JP0006874 W JP 0006874W WO 0124784 A3 WO0124784 A3 WO 0124784A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- new use
- inhibitor
- increasing
- plasminogen activator
- effect caused
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/43—Enzymes; Proenzymes; Derivatives thereof
- A61K38/46—Hydrolases (3)
- A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
- A61K38/49—Urokinase; Tissue plasminogen activator
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biomedical Technology (AREA)
- Immunology (AREA)
- Gastroenterology & Hepatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Epidemiology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
Priority Applications (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP00963073A EP1223969A2 (en) | 1999-10-04 | 2000-10-02 | Combined use of a plasminogen activator and il-2 inhibitors for neuroprotection |
JP2001527783A JP2003510351A (en) | 1999-10-04 | 2000-10-02 | New applications |
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
AUPQ3249A AUPQ324999A0 (en) | 1999-10-04 | 1999-10-04 | New use |
AUPQ3249 | 1999-10-04 | ||
AUPQ5643 | 2000-02-15 | ||
AUPQ5643A AUPQ564300A0 (en) | 2000-02-15 | 2000-02-15 | New use |
Publications (2)
Publication Number | Publication Date |
---|---|
WO2001024784A2 WO2001024784A2 (en) | 2001-04-12 |
WO2001024784A3 true WO2001024784A3 (en) | 2002-05-10 |
Family
ID=25646165
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/JP2000/006874 WO2001024784A2 (en) | 1999-10-04 | 2000-10-02 | New use |
Country Status (3)
Country | Link |
---|---|
EP (1) | EP1223969A2 (en) |
JP (1) | JP2003510351A (en) |
WO (1) | WO2001024784A2 (en) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU2003230777A1 (en) * | 2002-03-29 | 2003-10-13 | The Johns Hopkins University | Intraventricular hemorrhage thrombolysis |
AU2015294769B2 (en) | 2014-07-24 | 2020-07-16 | Litevax B.V. | Adjuvants |
JP7455457B2 (en) * | 2019-05-10 | 2024-03-26 | タレンゲン インターナショナル リミテッド | Methods and drugs for treating amyotrophic lateral sclerosis |
CN115697386A (en) * | 2020-03-24 | 2023-02-03 | 泰伦基国际有限公司 | Method and medicine for treating Parkinson's disease |
WO2024094217A1 (en) * | 2022-11-04 | 2024-05-10 | 泰伦基国际有限公司 | Method for promoting pathological tdp-43 protein degradation, and drug |
Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5648351A (en) * | 1992-12-29 | 1997-07-15 | Fujisawa Pharmaceutical Co., Ltd. | Use of macrolides for the treatment of cerebral ischemia |
US5945432A (en) * | 1995-12-22 | 1999-08-31 | The University Of Vermont And State Agricultural College | Thrombolytic agents and thienopyridine derivatives in acute stroke |
-
2000
- 2000-10-02 JP JP2001527783A patent/JP2003510351A/en active Pending
- 2000-10-02 WO PCT/JP2000/006874 patent/WO2001024784A2/en not_active Application Discontinuation
- 2000-10-02 EP EP00963073A patent/EP1223969A2/en not_active Withdrawn
Patent Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5648351A (en) * | 1992-12-29 | 1997-07-15 | Fujisawa Pharmaceutical Co., Ltd. | Use of macrolides for the treatment of cerebral ischemia |
US5945432A (en) * | 1995-12-22 | 1999-08-31 | The University Of Vermont And State Agricultural College | Thrombolytic agents and thienopyridine derivatives in acute stroke |
Non-Patent Citations (7)
Title |
---|
BEDNAR M M ET AL: "COMBINATION TISSUE PLASMINOGEN ACTIVATOR AND TICLOPIDINE THERAPY INA RABBIT MODEL OF ACUTE THROMBOEMBOLIC STROKE", NEUROLOGICAL RESEARCH,XX,XX, vol. 18, no. 1, 1 February 1996 (1996-02-01), pages 45 - 48, XP000646532 * |
BOCHELEN D ET AL: "CALCINEURIN INHIBITORS FK506 AND SDZ ASM 981 ALLEVIATE THE OUTCOME OF FOCAL CEREBRAL ISCHEMIC/REPERFUSION INJURY", JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS,AMERICAN SOCIETY FOR PHARMACOLOGY AND,US, vol. 288, no. 2, February 1999 (1999-02-01), pages 653 - 659, XP000980203, ISSN: 0022-3565 * |
BUNDICK ET AL: "FK506 AS AN AGONIST TO INDUCE INHIBITION OF INTERLEUKIN 2 PRODUCTION", TRANSPLANTATION,US,WILLIAMS AND WILKINS, BALTIMORE, MD, vol. 53, no. 5, 1992, pages 1150 - 1153, XP000913592, ISSN: 0041-1337 * |
KIM YANG-HEE ET AL: "Nonproteolytic neuroprotection by human recombinant tissue plasminogen activator.", SCIENCE (WASHINGTON D C), vol. 284, no. 5414, 23 April 1999 (1999-04-23), pages 647 - 650, XP002164663, ISSN: 0036-8075 * |
MAEDA MASASHI ET AL: "FK506 (tacrolimus) as a potential anti-stroke agent (3): Increased therapeutic efficacy with combined treatment of FK506 and recombinant tissue plasminogen activator (rt-PA) in a rat stroke model.", JAPANESE JOURNAL OF PHARMACOLOGY, vol. 82, no. Suppl. 1, 2000, 73rd Annual Meeting of the Japanese Pharmacological Society.;Yokohama, Japan; March 23-25, 2000, pages 174P, XP000990982, ISSN: 0021-5198 * |
TOUNG THOMAS J ET AL: "Neuroprotective FK506 does not alter in vivo nitric oxide production during ischemia and early reperfusion in rats.", STROKE, vol. 30, no. 6, June 1999 (1999-06-01), pages 1279 - 1285, XP000980399, ISSN: 0039-2499 * |
YAGITA Y ET AL: "EFFECT OF IMMUNOSUPRESSANT FK506 ON ISCHEMIA-INDUCED DEGENERATION OF HIPPOCAMPAL NEURONS IN GERBILS", LIFE SCIENCES,PERGAMON PRESS, OXFORD,GB, vol. 59, no. 19, 1996, pages 1643 - 1650, XP000980211, ISSN: 0024-3205 * |
Also Published As
Publication number | Publication date |
---|---|
JP2003510351A (en) | 2003-03-18 |
EP1223969A2 (en) | 2002-07-24 |
WO2001024784A2 (en) | 2001-04-12 |
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