WO2001023553A3 - Metastasis-associated antigen c4.4a - Google Patents

Metastasis-associated antigen c4.4a Download PDF

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Publication number
WO2001023553A3
WO2001023553A3 PCT/EP2000/009567 EP0009567W WO0123553A3 WO 2001023553 A3 WO2001023553 A3 WO 2001023553A3 EP 0009567 W EP0009567 W EP 0009567W WO 0123553 A3 WO0123553 A3 WO 0123553A3
Authority
WO
WIPO (PCT)
Prior art keywords
associated antigen
metastasis
cells
metastasizing
relates
Prior art date
Application number
PCT/EP2000/009567
Other languages
French (fr)
Other versions
WO2001023553A2 (en
WO2001023553A9 (en
WO2001023553A8 (en
Inventor
Margot Zoeller
Marc Roesel
Jens Wuerfel
Original Assignee
Deutsches Krebsforsch
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Deutsches Krebsforsch filed Critical Deutsches Krebsforsch
Priority to EP00972663A priority Critical patent/EP1220919A2/en
Publication of WO2001023553A2 publication Critical patent/WO2001023553A2/en
Publication of WO2001023553A3 publication Critical patent/WO2001023553A3/en
Publication of WO2001023553A9 publication Critical patent/WO2001023553A9/en
Publication of WO2001023553A8 publication Critical patent/WO2001023553A8/en

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

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  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)

Abstract

The present invention relates to gene expression in normal cells and cells of metastasizing tumors and particularly to a novel metastasis-associated antigen, C4.4A, and isolated nucleic acid molecules encoding C4.4A. Also provided are vectors, host cells, antibodies, and recombinant methods for producing this human protein. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating proliferative disorders associated with a metastasizing tumor.
PCT/EP2000/009567 1999-09-29 2000-09-29 Metastasis-associated antigen c4.4a WO2001023553A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
EP00972663A EP1220919A2 (en) 1999-09-29 2000-09-29 Metastasis-associated antigen c4.4a

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US40778499A 1999-09-29 1999-09-29
US09/407,784 1999-09-29

Publications (4)

Publication Number Publication Date
WO2001023553A2 WO2001023553A2 (en) 2001-04-05
WO2001023553A3 true WO2001023553A3 (en) 2001-11-08
WO2001023553A9 WO2001023553A9 (en) 2001-12-06
WO2001023553A8 WO2001023553A8 (en) 2002-01-03

Family

ID=23613517

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP2000/009567 WO2001023553A2 (en) 1999-09-29 2000-09-29 Metastasis-associated antigen c4.4a

Country Status (2)

Country Link
EP (1) EP1220919A2 (en)
WO (1) WO2001023553A2 (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2305352A1 (en) 2004-04-02 2011-04-06 Merck Sharp & Dohme Corp. 5-alpha-reductase inhibitors for use in the treatment of men with metabolic and anthropometric disorders
US20120321619A1 (en) * 2009-12-09 2012-12-20 Bayer Intellectual Property Gmbh Anti-c4.4a antibodies and uses thereof
WO2011158883A1 (en) * 2010-06-15 2011-12-22 国立大学法人大阪大学 Antibody capable of determination of cancer prognosis, and cancer prognosis determination method
WO2012143497A2 (en) 2011-04-21 2012-10-26 Bayer Intellectual Property Gmbh Novel binder-drug conjugates (adcs) and their use
JP6720208B2 (en) 2015-04-17 2020-07-08 スプリング バイオサイエンス コーポレーション Antibodies, compositions, and immunohistochemical methods for detecting C4.4A

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999018202A2 (en) * 1997-10-08 1999-04-15 Sagami Chemical Research Center HUMAN PROTEINS HAVING TRANSMEMBRANE DOMAINS AND cDNAs ENCODING THESE PROTEINS
WO1999063088A2 (en) * 1998-06-02 1999-12-09 Genentech, Inc. Membrane-bound proteins and nucleic acids encoding the same
WO2000053758A2 (en) * 1999-03-08 2000-09-14 Genentech, Inc. Compositions and methods for the treatment of immune related diseases
WO2000073454A1 (en) * 1999-06-02 2000-12-07 Genentech, Inc. Secreted and transmembrane polypeptides and nucleic acids encoding the same
WO2000073348A2 (en) * 1999-06-02 2000-12-07 Genentech, Inc. Methods and compositions for inhibiting neoplastic cell growth

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999018202A2 (en) * 1997-10-08 1999-04-15 Sagami Chemical Research Center HUMAN PROTEINS HAVING TRANSMEMBRANE DOMAINS AND cDNAs ENCODING THESE PROTEINS
WO1999063088A2 (en) * 1998-06-02 1999-12-09 Genentech, Inc. Membrane-bound proteins and nucleic acids encoding the same
WO2000053758A2 (en) * 1999-03-08 2000-09-14 Genentech, Inc. Compositions and methods for the treatment of immune related diseases
WO2000073454A1 (en) * 1999-06-02 2000-12-07 Genentech, Inc. Secreted and transmembrane polypeptides and nucleic acids encoding the same
WO2000073348A2 (en) * 1999-06-02 2000-12-07 Genentech, Inc. Methods and compositions for inhibiting neoplastic cell growth

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
RÖSEL, M. ET AL: "Cloning and functional characterization of a new phosphatidyl-inositol anchored molecule of a metastasizing rat pancreatic tumor.", ONCOGENE, vol. 17, no. 15, 15 October 1998 (1998-10-15), pages 1989 - 2002, XP000990942, ISSN: 0950-9232 *

Also Published As

Publication number Publication date
WO2001023553A2 (en) 2001-04-05
EP1220919A2 (en) 2002-07-10
WO2001023553A9 (en) 2001-12-06
WO2001023553A8 (en) 2002-01-03

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