WO2001021162A3 - Treating allergic and inflammatory conditions using desloratadine - Google Patents

Treating allergic and inflammatory conditions using desloratadine Download PDF

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Publication number
WO2001021162A3
WO2001021162A3 PCT/US2000/025609 US0025609W WO0121162A3 WO 2001021162 A3 WO2001021162 A3 WO 2001021162A3 US 0025609 W US0025609 W US 0025609W WO 0121162 A3 WO0121162 A3 WO 0121162A3
Authority
WO
WIPO (PCT)
Prior art keywords
desloratadine
allergic
inflammatory conditions
treating allergic
baseline
Prior art date
Application number
PCT/US2000/025609
Other languages
French (fr)
Other versions
WO2001021162A2 (en
Inventor
Kim Allen Heithoff
Original Assignee
Schering Corp
Kim Allen Heithoff
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to US40059999A priority Critical
Priority to US09/400,599 priority
Application filed by Schering Corp, Kim Allen Heithoff filed Critical Schering Corp
Publication of WO2001021162A2 publication Critical patent/WO2001021162A2/en
Publication of WO2001021162A3 publication Critical patent/WO2001021162A3/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445Non condensed piperidines, e.g. piperocaine
    • A61K31/4523Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
    • A61K31/4545Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring hetero atom, e.g. pipamperone, anabasine

Abstract

The use of desloratadine for the preparation of a medicament for substantially returning work-related performance and/or workplace productivity of a person suffering from an allergic and/or inflammatory condition of the skin airway passages, e.g., season allergic rhinitis, perennial allergic rhinitis, atopic dermatitis, urticaria or allergic asthma to the person's baseline work-related performance and baseline workplace productivity.
PCT/US2000/025609 1999-09-22 2000-09-19 Treating allergic and inflammatory conditions using desloratadine WO2001021162A2 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
US40059999A true 1999-09-22 1999-09-22
US09/400,599 1999-09-22

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
JP2001524588A JP2003509459A (en) 1999-09-22 2000-09-19 Treatment of allergic and inflammatory conditions
CA 2383214 CA2383214A1 (en) 1999-09-22 2000-09-19 Treating allergic and inflammatory conditions
AU75897/00A AU7589700A (en) 1999-09-22 2000-09-19 Treating allergic and inflammatory conditions
EP20000965127 EP1214071A2 (en) 1999-09-22 2000-09-19 Treating allergic and inflammatory conditions using desloratadine

Publications (2)

Publication Number Publication Date
WO2001021162A2 WO2001021162A2 (en) 2001-03-29
WO2001021162A3 true WO2001021162A3 (en) 2002-03-07

Family

ID=23584252

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2000/025609 WO2001021162A2 (en) 1999-09-22 2000-09-19 Treating allergic and inflammatory conditions using desloratadine

Country Status (7)

Country Link
EP (1) EP1214071A2 (en)
JP (1) JP2003509459A (en)
AR (1) AR025724A1 (en)
AU (1) AU7589700A (en)
CA (1) CA2383214A1 (en)
PE (1) PE07522001A1 (en)
WO (1) WO2001021162A2 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7405223B2 (en) 2000-02-03 2008-07-29 Schering Corporation Treating allergic and inflammatory conditions

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4659716A (en) * 1984-02-15 1987-04-21 Schering Corporation Antihistaminic 8-(halo)-substituted 6,11-dihydro-11-(4-piperidylidene)-5H-benzo[5,6]cyclohepta[1,2-b]pyridines
US5595997A (en) * 1994-12-30 1997-01-21 Sepracor Inc. Methods and compositions for treating allergic rhinitis and other disorders using descarboethoxyloratadine
WO1998006394A1 (en) * 1996-08-16 1998-02-19 Schering Corporation Treatment of upper airway allergic responses with a combination of histamine receptor antagonists
WO1998034614A1 (en) * 1997-02-07 1998-08-13 Sepracor, Inc. Lactose-free, non-hygroscopic and anhydrous pharmaceutical compositions of descarboethoxyloratadine
WO1998048803A1 (en) * 1997-04-25 1998-11-05 Schering-Plough Kabushiki Kaisha Eyedrops
US5900421A (en) * 1997-02-11 1999-05-04 Sepracor Inc. Methods and compositions for treating allergic asthma and dermatitis using descarboethoxyloratadine

Patent Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4659716A (en) * 1984-02-15 1987-04-21 Schering Corporation Antihistaminic 8-(halo)-substituted 6,11-dihydro-11-(4-piperidylidene)-5H-benzo[5,6]cyclohepta[1,2-b]pyridines
US5595997A (en) * 1994-12-30 1997-01-21 Sepracor Inc. Methods and compositions for treating allergic rhinitis and other disorders using descarboethoxyloratadine
WO1998006394A1 (en) * 1996-08-16 1998-02-19 Schering Corporation Treatment of upper airway allergic responses with a combination of histamine receptor antagonists
WO1998034614A1 (en) * 1997-02-07 1998-08-13 Sepracor, Inc. Lactose-free, non-hygroscopic and anhydrous pharmaceutical compositions of descarboethoxyloratadine
US5900421A (en) * 1997-02-11 1999-05-04 Sepracor Inc. Methods and compositions for treating allergic asthma and dermatitis using descarboethoxyloratadine
WO1998048803A1 (en) * 1997-04-25 1998-11-05 Schering-Plough Kabushiki Kaisha Eyedrops
EP0978281A1 (en) * 1997-04-25 2000-02-09 Schering-Plough Kabushiki Kaisha Eyedrops

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
GENOVESE: "loratadine and desethoxycarbonyl loratadine...", CLINICAL AND EXPERIMENTAL ALLERGY, vol. 27, no. 5, 1997, pages 559 - 567, XP000998792 *
HANDLEY DEAN A ET AL: "Methods for treating dermatitis using descarboethoxyloratadine.", 25 April 2000, OFFICIAL GAZETTE OF THE UNITED STATES PATENT AND TRADEMARK OFFICE, VOL. 1233, NR. 4, PAGE(S) NO PAGINATION, APR. 25, 2000, ISSN: 0098-1133, XP000997862 *
MOLET, S. ET AL: "Inhibitory activity of loratadine and descarboxyethoxyloratadine on histamine-induced activation of endothelial cells", CLIN. EXP. ALLERGY ( 1997 ), 27(10), 1167-1174, XP000997866 *

Also Published As

Publication number Publication date
CA2383214A1 (en) 2001-03-29
AU7589700A (en) 2001-04-24
EP1214071A2 (en) 2002-06-19
JP2003509459A (en) 2003-03-11
WO2001021162A2 (en) 2001-03-29
AR025724A1 (en) 2002-12-11
PE07522001A1 (en) 2001-07-17

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