WO2001015497A1 - Procede et systeme de polymerisation regulee utilises dans la production de lentilles de contact - Google Patents

Procede et systeme de polymerisation regulee utilises dans la production de lentilles de contact Download PDF

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Publication number
WO2001015497A1
WO2001015497A1 PCT/US2000/022944 US0022944W WO0115497A1 WO 2001015497 A1 WO2001015497 A1 WO 2001015497A1 US 0022944 W US0022944 W US 0022944W WO 0115497 A1 WO0115497 A1 WO 0115497A1
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Prior art keywords
intensity
lamp
wavelength
voltage
electromagnetic radiation
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PCT/US2000/022944
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English (en)
Inventor
Terry Harris
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Bausch & Lomb Incorporated
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Publication date
Application filed by Bausch & Lomb Incorporated filed Critical Bausch & Lomb Incorporated
Priority to AU69226/00A priority Critical patent/AU6922600A/en
Publication of WO2001015497A1 publication Critical patent/WO2001015497A1/fr

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    • H—ELECTRICITY
    • H05—ELECTRIC TECHNIQUES NOT OTHERWISE PROVIDED FOR
    • H05B—ELECTRIC HEATING; ELECTRIC LIGHT SOURCES NOT OTHERWISE PROVIDED FOR; CIRCUIT ARRANGEMENTS FOR ELECTRIC LIGHT SOURCES, IN GENERAL
    • H05B41/00—Circuit arrangements or apparatus for igniting or operating discharge lamps
    • H05B41/14—Circuit arrangements
    • H05B41/36—Controlling
    • H05B41/38—Controlling the intensity of light
    • H05B41/39—Controlling the intensity of light continuously
    • H05B41/392—Controlling the intensity of light continuously using semiconductor devices, e.g. thyristor
    • H05B41/3921—Controlling the intensity of light continuously using semiconductor devices, e.g. thyristor with possibility of light intensity variations
    • H05B41/3922—Controlling the intensity of light continuously using semiconductor devices, e.g. thyristor with possibility of light intensity variations and measurement of the incident light

Definitions

  • the invention concerns a method of curing of contact lenses in a mold by closed loop control of the variation and/or change in intensity over time of the actinic radiation employed to cure the lens, thereby forming a lens article having preselected properties.
  • molding in which two mold surfaces define the surfaces of the lenses, but could conceivably be applied to spin-casting.
  • molding involves mixing monomer, comonomer, and/or macromer/prepolymer components with a photoinitiator, placing the mixture in a mold, and exposing the mixture to light of the particular wavelength to which the photoinitiator responds. This mixture can also be called a lens-material precursor mixture.
  • One class of commonly used photoinitiators is sensitive to ultraviolet (UV) light.
  • Molds enter the casting machine at an entry position and move from indexed position to indexed position, remaining at each index position for a particular amount of time, until the molds reach an exit position. Once the molds leave the casting machine, some manufacturers send them to a "post cure" table where they expose the molds to additional light, completing the curing of the mixture. Then, the manufacturer adds water to the cured lens to form a hydrogel.
  • Contact lens manufacturers typically consider the curing to be essentially a matter of total dosage of actinic radiation. In some cases, manufacturers attempt to cure with a large dose in order to minimize the time needed to cure the lens. In essence, contact lens manufacturers do not consider the active control of the change in the intensity of actinic radiation over time as a factor in obtaining preselected properties of a contact lens.
  • Contact lens manufacture suffers from a relative high failure rate so that many finished lenses must be thrown away. Maintaining the dimensional properties of the lens within required tolerance levels is difficult. For example, the diameter of lenses manufactured with current techniques can vary as much as 74 ⁇ m, or nearly 20% of the specified tolerances, which are typically on the order of 100 ⁇ m. Attempts have been made to improve dimensional consistency, for example, using different mold materials or mold designs. Modulus of contact lens materials is an important factor in lens comfort, and attempts have been made to develop lens-material precursor mixtures or formulations that provide the desired modulus in the molded product. However, some formulations that have some desired properties such as high Dk do not produce the required modulus in the finished lens. New formulations are therefore continuously developed and tested in order to find the right physical or clinical properties. Moreover, some contact lenses require high manufacturing costs because of the difficulty of extracting residual (incompletely cured) components from the lens after it is cured.
  • the design of the molds, the composition of the monomer mixes, and the cure process determine contact lens and material bulk properties, and variation in any of these will result in variation in the product.
  • the effect of light intensity in UV cure, for example, has been overlooked as a control to achieve an optimum and uniform product quality.
  • contact lens properties vary significantly depending on variations in the intensity of cure radiation over time.
  • properties of contact lenses such as diameter or sag (dimension properties), percentage of water content or modulus of elasticity (physical properties), and residual component extractable levels (chemical properties) can vary widely from lens to lens in part from fluctuations in lamp intensity fluctuations on the main and/or post cure tables.
  • the dimensional, physical, or chemical properties of contact lenses can be obtained by actively controlling the intensity of the light used to cure the lens over time.
  • My invention dramatically improves consistency of quality in hydrogel curing, specifically in contact lens manufacture. Rather than simply turning on curing lamps and leaving them to run at whatever intensity the line voltage and current can generate, I control the intensity by actively controlling power applied to the lamp or other light source. I have found that maintaining the lamps at constant intensity yields more consistent properties in the end products. In contact lens manufacture specifically, diameter and sag are far more consistent, and residual content of components is greatly reduced.
  • a closed loop control system for example, by sensing lamp intensity as a basis of controlling lamp power.
  • the variability of light intensity at the lamp can be controlled within : 40 ⁇ W/cm 2 and the need to measure the intensity of the process occurs only at regular PMS intervals.
  • the controller can also monitor and report lamp failure and near end of lamp life.
  • Other light-intensity profiles can be determined, depending on a given lens formulation (lens-material precursor mixture) and details of manufacture (for example, whether using a post cure heat).
  • the system is particularly useful in UV curing of polymers used in, for example, contact lens manufacture using index casting machines.
  • My invention can yield more consistent quality of such products since it can maintain UV intensity at a given level regardless of lamp aging, lamp and ballast manufacturing variability, line voltage fluctuations, and temperature effects.
  • My invention can also yield preselected properties of lenses to the extent they depend on the path of cure (the rate of dosage change, i.e., the variation of the light intensity over time).
  • FIG. 1 is a chart showing the emission spectrum of a typical light source for curing lenses, in this case a fluorescent lamp.
  • FIG. 2 is a chart showing output intensity of a fluorescent lamp as the number of hours of on time for the lamp increases.
  • FIG. 3 is a chart of the intensity of a fluorescent lamp as a function of temperature.
  • FIG. 4 is a chart of lamp intensity as a function of line voltage.
  • FIG. 5 is a chart showing lamp intensity variation in a typical fluorescent lamp in a typical usage situation after the lamp has been on and warmed up for some time.
  • FIG. 6 is a chart showing the behavior of a typical fluorescent lamp as it starts up.
  • FIG. 7A is a schematic block diagram of an exemplary embodiment of my curing system using an index casting machine as the curing machine.
  • FIG. 7B is a schematic block diagram of a preferred controller of the invention.
  • FIG. 8 is a schematic circuit diagram of a preferred zero crossing circuit of the invention.
  • FIG. 9 is a schematic diagram of a preferred ramp generator of the invention.
  • FIG. 10 is a schematic diagram of a preferred soft start circuit of the invention.
  • FIG. 11 is a schematic diagram of a preferred power on reset circuit of the invention.
  • FIG. 12 is a chart showing the typical spectral response of a preferred photodiode of the invention.
  • FIG. 13 is a schematic diagram of a preferred filter/error amplifier circuit of the invention.
  • FIG. 14 is a schematic diagram of a preferred limiter circuit of the invention.
  • FIG. 1 5 is a schematic diagram of a preferred phase modulator circuit of the invention.
  • FIG. 16 is a schematic diagram of a preferred power stage circuit of the invention.
  • FIG. 17 is a schematic diagram of a preferred alarm discrete circuit of the invention.
  • FIG. 18 is a schematic diagram of a preferred controller alarm circuit of the invention.
  • FIG. 19 is a chart showing the variation of the primary AC voltage, ramp voltage, triac trigger voltage, sensed light signal voltage, and filtered sensed light signal voltage produced by respective preferred circuits of the controller of FIG. 7A over time, thus illustrating the relative timings of the variations of the voltages.
  • the invention relates to the curing of a lens precursor material during the production of contact lenses and, more specifically, relates to curing systems in which radiation intensity is controlled.
  • the lens-material precursor mixture used in photoinitiated contact lens manufacture typically includes monomers and/or comonomers that result in a crosslinked polymer.
  • the lenses can be made from hydrophilic polymers, including polyhydroxyethyl methacrylate and polyvinyl pyrrolidinone based systems.
  • the present invention is applicable to contact lenses of the gel, hydrogel or soft type, whether made from the more traditional copolymers such as 2-hydroxyethyene methacrylate (HEMA) or from the newer silicon-containing hydrogel materials.
  • HEMA 2-hydroxyethyene methacrylate
  • preselected properties of the lenses can be obtained by applying my inventive system of actively controlling UV intensity or other actinic radiation.
  • a system 6 modifies existing curing systems by adding a light sensor 11 for each lamp 3 or bank of lamps in a curing machine 7, such as an index casting machine.
  • An index casting machine can include a main table 7a with clamping positions 7b onto which molds 7c containing polymer precursor mixture to be cured can be placed and removed through entry and exit positions 6a, 6b.
  • a post cure table 8 can also be included.
  • the light sensor 11 produces a voltage proportional to light incident on the sensor.
  • the system 6 modifies and monitors this voltage to produce a control signal for the power stage 28 (see FIG. 7B) of the curing machine so that the lamps 3 produce a desired intensity of the curing radiation. Details of an exemplary embodiment of my inventive system follow.
  • a variety of sources for cure radiation can be employed in contact lens manufacture to cure hydrogel materials, including but not limited to fluorescent lamps, high-pressure or low-pressure mercury vapor lamps, excimer lasers, and the like.
  • An economical choice for a UV lamp is the low-pressure, mercury fluorescent lamp known as the PL-S 9W/10.
  • the PL-S style lamp is a two pin, twin tube, compact fluorescent lamp with an integral starter and produces the bulk of its light between 350-800 nm.
  • FIG. 1 shows the typical emission spectrum of such a PL-S lamp.
  • a typical lamp and ballast configuration running continuously under nominal conditions of line and temperature can produce intensity levels, measured at or near the lamp, as high as 12 mW/cm 2 during the first few hours of life to as low as 3 mW/cm 2 after 2000 hours of continuous use.
  • the degradation in intensity level results from uncontrolled on/off cycling of the lamp, which can cause degradation of the phosphor coating of the lamp from sputtering.
  • This 4 to 1 reduction in lamp output over the life of the lamp is typical even though the actual intensity levels depend heavily on the measurement system and the conditions under which the measurements were taken.
  • FIG. 2 shows the relationship of intensity as a function power on hours (POH) for a typical lamp used on a casting machine measured using a UV gauge.
  • This intensity is the combination of gauge response and lamp spectral emission and represents the total energy in the emitted spectrum.
  • the intensity decreases in an exponential-like fashion from 5500 ⁇ W/cm 2 at day 10 to 3500 ⁇ WVcm 2 at day 80 and may be due to tube glass solarization, phosphor degradation, or impurities in the gas.
  • POH only accumulate when the lamp is on, as the name suggests.
  • the intensity of the lamp is also affected by temperature as shown in FIG. 3.
  • the lamp's output is dominated by the quantum conversion efficiency of the lamp gas. This phenomenon is a function of current density of the discharge column, which depends on the vapor pressure of the gas and current flowing through the lamp. For fixed lamp current, the current density increases as temperature increases due to increased vapor pressure. At higher temperatures, the phosphor coating's conversion efficiency decreases as temperature increases and becomes the factor dominating the output.
  • FIG. 4 shows the relationship between line input voltage and lamp intensity.
  • the first part of the plot shows the lamp's intensity at 120 VAC, the second at 100 VAC, and the third at 140 VAC.
  • the voltage affects intensity at about 100 ⁇ W/cm 2 ⁇ /RMS.
  • ballast inductance accounts for as much as 1000 ⁇ W/cm 2 as a result of the relationships discussed above.
  • Actinic radiation in the UV and/or visible light spectrum is preferred for curing contact lenses. Intensity is affected by the location of the lamp relative to its reflector, the shape of the reflector, the surface condition of the reflector, and the interaction of the light spectral response to any transmission medium including, in the case of contact lens manufacture with index casting machines , mold material and casting chamber covers.
  • any spatial differences in the orientation of the mold relative to the source between casting positions will add to the variability of intensity at the mold.
  • the epsiion or delta series indexing machines use three clamp positions and the Quattro series use four.
  • the spatial response to a single light source is different across the clamp positions and is estimated at 600 ⁇ V cm 2 for the former and 1000 ⁇ W/cm 2 for the latter casting machine series.
  • light from each lamp adjacent to a particular clamp position aids the lamp directly above the clamp position as do the lamps adjacent to these lamps, etc.
  • An ideal scheme to control intensity would incorporate power and temperature control.
  • the system in response to sensed visible light, the system is capable of regulating UV light intensity to within 40 ⁇ W/cm 2 of the set point for a given temperature, intensity again being measured at or near the lamp.
  • One solution for the control regulates temperature; another neutralizes the effect of temperature.
  • FIG. 5 shows a typical intensity plot over time for both open loop and closed loop operation.
  • FIG. 6 shows a plot of UV intensity vs. time at start up for a PL-S lamp with and without closed loop control. The plot shows that at 5 minutes the open loop lamp intensity is still climbing to the final value whereas the closed loop lamp's intensity stabilized within about 15 seconds.
  • FIG. 7B shows a block diagram of an exemplary embodiment of a closed loop system 1 for use in one embodiment of the present invention.
  • the intensity of light emitted by the lamp 3 is controlled when driven by an AC power source 2 and the controller 1.
  • the exemplary controller of FIG. 7B includes the photosensor, such as the light detector 11 , preferably disposed on an LTV (Light to Voltage) distribution board 10 and connected to a filter 21 (such as a low pass filter) on a control board 20 that also carries a comparator 22 (such as a summation circuit), an error amplifier 23, a limiter circuit 24, an alarm circuit 25, a phase modulator 26, a triac drive 27, and a power stage 28.
  • the filter 21 is connected to the comparator 22, which in turn is connected to the error amplifier 23, which sends its output to the limiter circuit 24.
  • the limiter 24 sends its output to the phase modulator 26, which controls the triac drive 27 via a one-shot 26a; and the triac drive 26 controls the power stage 28.
  • the phase modulator 26 of the exemplary controller 1 in FIG. 7B is also connected to a control device 30, such as a programmable logic controller (PLC), and to components on a timing and alarm board 40, including a power on reset circuit 41 , which is also connected to the control device 30, and a ramp generator 42, which is connected to a soft start circuit 43 and a zero crossing detector 44.
  • the alarm circuit 25 of the control board 20 is connected to another alarm circuit 45 on the timing and alarm board 40, which is also connected to the control device 30.
  • the output voltage of the photosensor 11 is filtered by a filter 21 , such as a low pass filter, and scaled to produce a DC voltage inversely proportional to the incident light intensity.
  • a filter 21 such as a low pass filter
  • the filtered, scaled DC voltage level decreases.
  • This voltage is compared to a reference (set point) voltage at the comparator 22, and the difference is amplified by the error amplifier 23. Under steady state conditions, these voltages would be the same and the output from the error amplifier 23 would be some constant value. However, due to the disturbance of increased incident intensity, an unbalanced condition exists and the output voltage from the error amplifier 23 increases.
  • the limiter circuit 24 will limit this voltage, but if not, the limiter circuit 24 has no effect on the control and the signal passes through undisturbed.
  • the error amplifier voltage is applied to the phase modulator 26 and increases the delay in triggering the triac drive 27 and power stage 28. This delay decreases the power supplied to the load, which decreases the lamp's intensity proportionally. This decrease in power produces the correct adjustment through careful selection of gain and dynamic compensation of the error amplifier 23. If the disturbance is a decrease in line voltage, the description of the process is the same except the word "decrease" replaces the word "increase.”
  • a group of circuits produce a logic level low pulse of about 10O ⁇ sec every time the AC primary voltage crosses zero. This pulse provides the timing to terminate and initiate a new voltage ramp cycle and controls the firing phase angle of the power stage.
  • FIG. 8 shows the schematic of this circuit, the zero crossing detector 44.
  • a sample of the sinusoidal AC primary voltage from the AC power source 2 is sensed across a transformer T1 and squared up by a clamped, analog voltage comparator 441 , preferably including a LM339 unit, that produces a symmetric square wave.
  • Resistors R5 and R6 provide a small amount of hysteresis to suppress spurious oscillations near the zero crossing point and resistors R4/R5 and resistors R3/R2 bias the signal into the range of the single supply voltage comparator.
  • This waveform is applied to a "one-shot" multivibrator 441 triggered on the rising edge of the square wave and also to another one-shot triggered 442 on the falling edge of the square wave.
  • both one-shots are 74LS123 units.
  • Resistor R7 provides a TTL logic compatible high level to the preferred 74LS123 trigger inputs and resistor R8/capacitor C2 and resistor R9/capacitor C3 determine the pulse widths at the outputs.
  • the ramp generator shown in FIG. 9 preferably includes an open collector, logic compatible comparator 421 , and a constant current source U4.
  • the outputs of the zero crossing detector's one-shots are "wire-ANDed" together at the input 422 to the comparator 421 to produce a 100 ⁇ sec pulse at two times the AC primary frequency. While these specific values for the pulse duration and frequency are preferred, other durations and frequencies can be used depending on the particular needs of the user.
  • a precision constant current source programmed by a potentiometer preferably charges a capacitor C4 creating a linearly rising ramp.
  • the comparator terminates the ramp cycle by applying the short across the timing capacitor.
  • the charging rate and the time between reset pulses determines the maximum voltage the ramp attains; I prefer to set the voltage to about 7 V.
  • the comparator is preferably made TTL logic compatible by setting the logic high level to .45V via the voltage divider R13/R14.
  • the one-shot pulses are summed using resistor R10, resistor R11 , and resistor R12 such that any one low logic level is guaranteed to produce less than the .45V at the positive input and two logic level highs are required to produce a voltage greater than the .45V.
  • the comparator applies ground to its output discharging capacitor C4.
  • Resistor R15 is used to program the constant current source U4 and charges capacitor C4 at a constant rate. Since the voltage on a capacitor is equal to the product of the capacitor current times the time the current flows divided by the capacitance, a constant charging current will produce a linear voltage ramp.
  • the open collector transistor at the output of the comparator discharges the timing capacitor every time a one-shot triggers, which resets the capacitor voltage to zero and begins a new cycle once the short is removed.
  • the ramp voltage amplitude is preferably reduced below the minimum clamped error signal of the control loops by diverting ramp charging current away from the ramp capacitor 431. Since the ramp voltage is less than the error signal, power stage trigger pulses are inhibited and the lamp 3 is turned off, as is discussed in the description of the phase modulator.
  • a voltage controlled current sink 432 diverts the ramp capacitor charging current so that the final ramp voltage is allowed to increase with time.
  • trigger pulses are again delivered to the power stage every half cycle of the AC line voltage. As the ramp voltage increases, the trigger delay decreases, which in turn increases the current delivered to the lamp filaments. The slowly increasing lamp current warms the filaments slowly and eliminates the cold start stresses.
  • FIG. 10 shows the implementation of this circuit.
  • the current sink 432 includes op-amp U5, transistor Q5, and resistor R18.
  • the large gain of op-amp U5 guarantees that the inverting and non-inverting terminals of the op amp are at the same potential.
  • the non-inverting op amp configuration applies a voltage necessary at pin 1 to cause transistor Q5 to conduct and sink current such that the voltage drop across resistor R18 is equal to the voltage at the non-inverting input.
  • the voltage at pin 3 is a linearly falling ramp that starts at ground and decreases to a predetermined voltage over a predetermined period. Preferably, the voltage drops to about -5 volts in about 3 seconds. This signal diverts the ramp capacitor's charging current from about 9 ⁇ A at start to zero current at the end of the time out. I prefer to use a 2N2222 transistor at Q5 and a 560K ⁇ resistor at R18.
  • Resistor R25 through resistor R27 and transistor Q3 form a 2.5 ⁇ A constant current source 433 that charges capacitor C9 forming a ramp generator 434.
  • the ramp is linear from ground to about -4.3 volts where transistor Q3 saturates. After saturation, the cap continues to charge to -5 volts at an exponential rate.
  • Reset of capacitor C9 is provided by the optocoupler U8 which is controlled by * POR. I prefer to use 3.9K ⁇ , 1.2K ⁇ , and 200K ⁇ resistors at R25, R26, and R27, respectively; a 1 ⁇ F capacitor at C9; a 2N2222 transistor at Q3; and a CNY 17-1 optocoupler at U8.
  • Power on reset ( * POR, the asterisk signifying active low) is provided after powering up of the system, particularly the timing and alarm board, to allow the power supply voltages time to stabilize and also to guarantee known start up conditions for all circuitry.
  • * POR is also gated with the PLC ON" signal and is used to provide lamp on/off control.
  • a single power on reset can be used; and the * POR can be made available to each respective phase modulator in this case so that, when the power on reset is active, it turns each lamp off.
  • * POR can also be applied to the soft start circuit.
  • FIG. 1 1 shows a preferred arrangement of the power on reset circuit 41.
  • Constant current source U3 and resistor R17 provide a constant current of about 2.4 ⁇ A into capacitor C1 , which produces a linear voltage ramp.
  • This voltage is compared to the 4.3 V output of the voltage divider 411 , including resistor R19 and resistor R20, by comparator U2. Until the ramp exceeds 4.3 volts, the voltage comparator's output is at ground, which removes base drive from transistor Q1 , turning it off. With transistor Q1 off, base drive is available to transistor Q2, which turns it on pulling * POR to ground.
  • Transistor Q1 is biased on through resistor R23, which removes base drive from transistor Q2, turning it off.
  • Resistors R21 and R22 provide hysteresis to eliminate oscillations near the comparator's switching point.
  • Transistors Q1 and Q2, resistor R23, and resistor R24 provide increased current sinking capability for the load on * POR. I prefer to use 270K ⁇ , 1.5K ⁇ , 2.7K ⁇ , and 1 M ⁇ resistors at R17, R19, R21, and R22, respectively, and 10K ⁇ resistors at R20, R23, and R24. I also prefer to use a LM339 unit at U2, a LM334 constant current source at U3, and 2N2222 transistors at Q1 and Q2.
  • PLC on/off control is accomplished by optocoupler U9, resistor R32, resistor R33, and transistor Q7.
  • the PLC provides a 24 V logic discrete, which indicates a lamp on condition. This voltage biases the LED portion of the optocoupler U9 on through resistor R32. The transistor portion then conducts and removes base drive from transistor Q7, turning it off. This allows the controller to turn lamps on under normal control.
  • the 24 V discrete is removed, the LED and transistor of U9 turn off and base drive is restored to transistor Q7, which turns on and sinks the base drive of transistor Q1 , making * POR true as explained above. This action results in the lamps turning off.
  • Light is preferably sensed using a Texas Instruments TSL252 light to voltage converter 11 operating on a 5 V DC supply.
  • the preferred spectral response shown in FIG. 12 is from 300 nm to 1100 nm.
  • the detector also has sufficient wavelength bandwidth to faithfully reproduce the 120 Hz light pulse signal from the lamp and is shown in FIG. 19.
  • the sensor is coupled to the lamp by means of a fiber optic cable.
  • the detector includes a filter or other device with a 600 nm cutoff that effectively creates a 600 nm to 1100 nm spectral bandwidth system. The energy contained in the bandwidth is integrated by the TSL252 and delivered as a voltage waveform.
  • the output of the light sensor 10 is preferably scaled and filtered to provide a low ripple DC voltage of 0-5 VDC over the range of programmable lamp intensities.
  • FIG. 13 shows a preferred exemplary arrangement of the filter 21 and error amplifier circuit 23, which also preferably includes the summation circuit 22.
  • the scaling can be adjustable and can be used for calibrating the controller to match the PLC control voltage range. Minimum lamp intensity is attained at 5 VDC, and maximum lamp intensity is attained at 0 VDC.
  • Capacitor C8 provides filtering and, with resistor R101 , sets a pole at 10 Hz. Resistors R102 and R103 provide offset adjustment, and resistors R104 and R101 provide span adjustment.
  • FIG. 19 shows the effect of the filter 21 for a typical TSL output.
  • a lossy integrating error amplifier is provided to compensate the control loop feedback and provide for stable operation.
  • the amplifier operates in a differential mode with the conditioned intensity voltage and the set point control voltage as inputs.
  • the loop gain is set by the feedback capacitor C7 and resistor R100 with a pole at about 3Hz. Bandwidth of the loop is determined by the filtering stage preceding the error amplifier and the feed back pole.
  • the output of the error amplifier is a DC control voltage used to modulate the firing angle of the power stage.
  • FIG. 19 shows the timing for these waveforms.
  • the phase modulation control voltage must be limited to an upper and lower level to guarantee stable operation due to the inductive nature of the load and the lower permissible operating temperature of the lamp 3. This is accomplished by the precision clamping circuit with independently adjustable upper and lower limits included in the preferred limiter circuit 24 shown in FIG. 14.
  • the phase modulation control voltage is unaffected by this circuit as long as its voltage remains between the limits of V mjn and V max .
  • the lower limit establishes the maximum intensity (minimum phase delay) that the lamp can produce
  • the upper limit establishes the minimum intensity (maximum phase delay) that the lamp can produce. Any phase delay less than the minimum phase determined by the power factor of the load will result in an additional 180° of phase in the control loop and will cause the controller to become unstable. This instability will cause the lamp to cycle on and off and will eventually destroy the lamp. Any phase delay greater than the maximum will cause the lamp to cool too much, resulting again in on and off cycling and eventual destruction of the lamp.
  • both op amps 243, 244 operate in open loop fashion and become saturated with an output voltage that back biases diodes D1 and D2. If the error voltage increases above V max , then the upper op amp's 243 output will be driven low enough to forward bias diode D1 through resistor R94 and close the feedback loop, creating a non-inverting unity gain amplifier. The inverting and non-inverting inputs of this op amp 243 would then be at the same potential, which is V max . Any additional voltage provided from the error voltage would be dropped across resistor R94.
  • the lower op amp's 244 output will be driven high enough to forward bias diode D2 and close the feedback loop, again creating a non-inverting unity gain amplifier.
  • the output of the amplifier would be V m ⁇ n , and any additional voltage provided from the error voltage would be dropped across resistor R94, as well.
  • the preferred arrangement of the phase modulator of the invention shown in FIG. 15 includes a comparator, a one-shot, and an optocoupler U14.
  • the phase modulation control voltage is preferably compared to the ramp voltage to produce a high-to-low logic transition when the ramp voltage exceeds the control voltage and a low-to-high transition when the control voltage exceeds the ramp voltage.
  • the falling edge of this waveform triggers a one-shot to produce a 200 ⁇ sec pulse used to initiate conduction of the power stage.
  • the pulse is isolated from the load by an optocoupled triac driver.
  • the switch can be used to turn the triac on continuously in the bypass mode or to inhibit the triac in the off mode.
  • *POR is used to momentarily inhibit triggering of the power stage after power up.
  • FIG. 19 shows the timing for these waveforms.
  • the error signal is preferably compared to the ramp voltage by comparator U10 and initiates a high-to-low transition at its output when the ramp voltage is greater than the error voltage.
  • This transition momentarily couples what is substantially ground (a true ground is nearly impossible to achieve here, so there is a small, negligibly residual voltage) across capacitor C5 that removes base drive from transistor Q17, turning it off.
  • the off state of transistor Q17 allows transistor Q18 to regain its base drive and turn on conducting the optocoupler's LED bias current, which in turn drives the optotriac into conduction.
  • the current supplied from the optotriac is used to trigger the power triac.
  • capacitor C5 When capacitor C5 reaches a preferred voltage of about 0.7 V by charging through resistor R95, transistor Q17 begins to conduct again and removes base drive from transistor Q18, turning it off. The LED bias current is removed and the optotriac output current is removed from the power triac. At the end of a predetermined ramp voltage cycle, preferably 8.33 msec, the ramp voltage is reset to ground and the comparator's output transitions from low-to-high pulled up through resistor R89.
  • the timing capacitor C5 couples the 5 V pull-up voltage across itself and discharges through transistor Q17's base/emitter junction and resistor R89. Since resistor R89 is less than resistor R95, the discharge time constant is a fraction of the charge time constant, which guarantees a return to a stable start condition.
  • the controller can be bypassed and the lamp turned on fully by applying ground to the base of transistor Q17.
  • Switch S2 provides this function, which removes base drive from transistor Q17, turning it off continuously. With transistor Q17 off, transistor Q18 will be on, which enables continuous LED and optotriac current and, hence, the power triac will be conducting continuously. Continuous conduction will apply full voltage to the lamp, and lamp voltage must be kept below a predetermined level in this mode to avoid lamp failure and to enhance safety.
  • Lamps can be turned off by applying ground to the output of the comparator, which inhibits the discharging of capacitor C5 and keeps transistor Q17 conducting continuously. This state will turn the power triac off until the ground is removed as explained above.
  • the power stage includes a RC snubber circuit (resistor R98, resistor R99, and capacitor C6, preferably of 180 ⁇ , 680 ⁇ , and 0.068 ⁇ F, respectively) and a triac (Q25) as shown in FIG. 16.
  • the triac is used to switch the hot side of the AC load and is applied to the lamp ballast.
  • the snubber reduces stress on the triac and output of the optocoupler.
  • Each alarm control circuit 250 monitors the control voltage necessary to produce the desired UV intensity from the lamp it is controlling. Two active low signals are produced and used to drive three front panel indicating lamps. These lamps signal green for normal operation, yellow if the control voltage is near the end of its operating range, and red if the control is beyond its operating range.
  • Each of the active low signals are combined with others of their kind from the rest of the control circuits to provide two separate digital discretes 450 to indicate controller status to the PLC.
  • Each discrete 450 is preferably made available as an uncommitted, optocoupled transistor output located on the Timing and Alarm Board in the alarms circuit 45.
  • the first discrete 450 indicates whether any control circuit is failing to control its lamp's intensity as would happen if the lamp 3 burned out or was unable to produce the required intensity set by the PLC.
  • the second discrete 450 indicates if any control circuit is near the end of its controllable range as would happen if a lamp were near the end of its usable life. Both are powered from the 5 V power supply such that a failure of the power supply will look like two alarm conditions to the PLC.
  • control board An option is available on the control board to disable an individual control circuit's contribution to the alarm or warning discretes but still indicate the state of the control signal at the front panel by the LEDs.
  • This optional control is preferably located in the alarm control circuit area represented by the control board alarm circuit 25 shown in FIG. 7, an exemplary control circuit of which is shown in FIG. 18.
  • FIG. 17 shows the preferred topology used for both logic discretes 450.
  • Resistor R31 provides base drive for transistor Q4 enabling bias current for the LED 451 of optocoupler U6 to flow under non-alarm conditions. With the LED bias current flowing, the optocoupler output transistor 452 can conduct current supplied from the PLC input logic device. When * Warn ( * Alarm) goes low, the base drive is removed from transistor Q4 and the LED bias current is removed. The optocoupler's output transistor 452 will no longer conduct any current and can hold off up to 70 volts from the PLC logic input device. I prefer to use resistors of 330 ⁇ and 10K ⁇ at R30 and R31 , respectively; a 2N2222 transistor at Q4; and a CNY 17-1 optocoupled transistor at U6.
  • Each alarm control circuit 250 preferably has a window comparator 251 that compares the phase modulator control voltage to V max and V min as shown in FIG. 18. If the control voltage is less than V max , pin 14 of comparator U3 will be pulled high through resistor R12; or if the control voltage is greater than V min , pin 13 of comparator U3 will be pulled high through resistor R9. This voltage is applied to the red LED drive circuit 252 (which includes resistor R1 , resistor R5, transistor Q1 , and L1 ) and the green LED drive circuit 253 (which includes resistor R4, resistor R3, resistor R2, and transistors Q2 and Q4).
  • the voltage applied to the red and green LED drive circuits 252, 253 turns the red LED off and the green LED on, indicating a normal operating condition for this control circuit.
  • the signal is also applied to the open collector nand gate U1 , along with 'Disable, an active low discrete. Whenever * Disable is active, the output of open collector nand gate U1 pin 3 ( * fau ⁇ t) will be open collector regardless of the state of the other signal; but when * Disable is inactive, the output will be low when this signal is high or high when this signal is low.
  • the lamp can only be regulated to an intensity below that which it could go to if it was driven off the line by the standard ballast scheme.
  • the system takes advantage of the relationship between increased intensity and increased voltages. For example, the AC primary voltage is stepped up to 140 VRMS so that a lamp that normally operates at 10 mW/cm 2 at a line voltage of 120 VRMS would produce 12 mW/cm 2 at a line voltage of 140 VRMS.
  • the controller can now reduce the current into the lamp to restore the intensity down to the 10 mW/cm 2 level and have enough overhead to compensate for a 2 mW/cm 2 reduction in intensity due the aging of the lamp.
  • a typical cure process can comprise a main table and post cure table time and, for some systems, post cure table temperature.
  • Other processes may employ a conveyor belt to transport the lenses and molds through a curing zone.
  • the method according to the present invention comprises curing contact lenses in their molds by actively controlling exposure of an uncured mixture to electromagnetic radiation of specified wavelength and intensity over a particular period of time (which period of time may be the whole or any part of the overall curing time), thereby forming a desired contact lens into a predesigned shape and with preselected properties.
  • the intensity of radiation is within 3500 ⁇ W to 7000 ⁇ W for a period of time ranging from 3 minutes to 90 minutes, preferably 5 minutes to 45 minutes, more preferably about 10 minutes to about 30 minutes.
  • the intensity of radiation can be controlled by a closed loop system, one such embodiment of a closed loop system having been described above.
  • the variation of intensity from the desired light intensity over said time period is maintained within a range of +/-
  • the intensity may be maintained constant in some cases, it may be advantageous to vary the desired light intensity over said time period. This may depend not only on the intensity of the lamp per se, but on the number of lamps in a given space and the relative position of the lamps and molds.
  • the light intensity emitted from the lamps are set at three or more different light intensities (the intensity of a lamp can be measured, for example, using a standard radiometer) and the intensity at the material being cured can be correlated.
  • the same type of lamp can have three or more intensities or three different types of lamps having different intensities can be employed.
  • the desired light intensity over said time period can increase continuously over said time period linearly or non-linearly.
  • the desired light intensity can be made to ramp up or ramp down over said time period, for example, in a main table cure or in a post cure.
  • One preferred embodiment is to ramp the intensity up, then down in both a main cure and post cure.
  • the light source for each index which typically lasts 30 seconds, can be individually controlled, the series of indexes, for example, increasing in a stair-step manner.
  • the desired light intensity profile over time can be determined or optimized for a given lens material or mold system by testing various profiles and selecting the profile that produces the best results in terms of lens properties.
  • the profiles can be determined by experimental design employing, for example, a multiple response optimization algorithm, through manipulation of the intensities controlled by the light-source controller and examination of the properties of the lens after cure. Once the optimum profile is established, the controllers are programmed to deliver the exact dose at the right time.
  • the path of cure (based on the intensity profile of the actinic radiation to which the lens is exposed over time) can be varied to find the path that results in the optimal or most consistent properties or combinations of properties, including lens diameter, sag, center thickness, water content, extractable levels, tear, and/or modulus.
  • a casting process equipped with UV lamps and controllers could be used to establish an intensity profile that optimizes the cure by delivering a precise and timely radiation dose(s) to a monomer system as it cures.

Landscapes

  • Circuit Arrangement For Electric Light Sources In General (AREA)

Abstract

L'invention concerne un système de polymérisation dans lequel l'exposition d'un mélange de précurseur de polymère à un rayonnement de durcissement se caractérise par une régulation efficace de l'intensité de ce rayonnement de durcissement, ce qui permet d'améliorer considérablement la production de produits polymériques, leur qualité étant généralement plus élevée et constante. Un programme de commande en boucle fermée permet de régler l'intensité d'une lampe PL-S à une longueur d'onde en détectant la production de lumière de cette lampe à une autre longueur d'onde et en régulant la puissance de la lampe à l'aide d'une modulation de phase CA. Ce programme régule de préférence l'intensité UV en fonction de la lumière visible détectée émise par la lampe. Ledit programme permet de compenser la variabilité de fabrication de la lampe et du ballast, les effets de température, les variations de tension sectorielle et le vieillissement de la lampe. Une unité de commande peut régler l'intensité de plusieurs batteries de lampes, chaque lampe pouvant être affectée à chaque batterie. Une fois réglée, la variabilité de l'intensité lumineuse UV, telle que mesurée sensiblement au niveau de la lampe, est maintenue à +40 νW/cm2, la mesure de l'intensité du processus n'étant nécessaire qu'à des intervalles PMS réguliers. L'unité de commande permet de détecter et de rapporter les défaillances de la lampe et la proximité de la fin de vie de cette lampe. Des circuits de mise sous tension sans appel de courant éliminent les tensions d'alternance marche/arrêt; la mise en marche des lampes en cas de nécessité uniquement permet alors d'augmenter la durée de vie utile de ces lampes. Par ailleurs, le système réduit les temps de réchauffement habituellement longs observés avec les techniques antérieures à moins d'une minute, voire à quelques secondes seulement.
PCT/US2000/022944 1999-08-23 2000-08-21 Procede et systeme de polymerisation regulee utilises dans la production de lentilles de contact WO2001015497A1 (fr)

Priority Applications (1)

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AU69226/00A AU6922600A (en) 1999-08-23 2000-08-21 Method of and system for controlled curing of polymers used in contact lens manufacture

Applications Claiming Priority (2)

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US15024599P 1999-08-23 1999-08-23
US60/150,245 1999-08-23

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Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1436806A2 (fr) * 2001-10-17 2004-07-14 Coltene/Whaledent, Inc. Appareil sous forme de lampe de durcissement a voix electronique
US7785092B2 (en) 2005-08-09 2010-08-31 Coopervision International Holding Company, Lp Systems and methods for producing contact lenses from a polymerizable composition
US7799249B2 (en) 2005-08-09 2010-09-21 Coopervision International Holding Company, Lp Systems and methods for producing silicone hydrogel contact lenses
US8293154B2 (en) 2004-01-13 2012-10-23 Polymer Sciences Limited Moulding process
WO2018020398A1 (fr) * 2016-07-29 2018-02-01 3M Innovative Properties Company Systèmes et procédés de surveillance de durcissement

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999006887A1 (fr) * 1997-07-31 1999-02-11 Q2100, Inc. Procede et composition permettant de produire des verres absorbant une lumiere d'activation

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999006887A1 (fr) * 1997-07-31 1999-02-11 Q2100, Inc. Procede et composition permettant de produire des verres absorbant une lumiere d'activation

Cited By (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1436806A2 (fr) * 2001-10-17 2004-07-14 Coltene/Whaledent, Inc. Appareil sous forme de lampe de durcissement a voix electronique
EP1436806A4 (fr) * 2001-10-17 2005-01-05 Coltene Whaledent Inc Appareil sous forme de lampe de durcissement a voix electronique
US7167829B2 (en) 2001-10-17 2007-01-23 Coltene / Whaledent Inc. Curing lamp apparatus giving operating conditions with electronic voice
US8293154B2 (en) 2004-01-13 2012-10-23 Polymer Sciences Limited Moulding process
US7785092B2 (en) 2005-08-09 2010-08-31 Coopervision International Holding Company, Lp Systems and methods for producing contact lenses from a polymerizable composition
US7799249B2 (en) 2005-08-09 2010-09-21 Coopervision International Holding Company, Lp Systems and methods for producing silicone hydrogel contact lenses
US7897071B2 (en) 2005-08-09 2011-03-01 Coopervision International Holding Company, Lp Systems and methods for producing silicone hydrogel contact lenses
US8298458B2 (en) 2005-08-09 2012-10-30 Coopervision International Holding Company, Lp Systems and methods for producing silicone hydrogel contact lenses from a polymerizable composition
US8308999B2 (en) 2005-08-09 2012-11-13 Coopervision International Holding Company, Lp Systems and methods for producing contact lenses from a polymerizable composition
WO2018020398A1 (fr) * 2016-07-29 2018-02-01 3M Innovative Properties Company Systèmes et procédés de surveillance de durcissement
US10746660B2 (en) 2016-07-29 2020-08-18 3M Innovative Properties Company Cure monitoring systems and methods

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