WO2001003515A8 - Method of obtaining protein isolates and concentrates from colostrum - Google Patents

Method of obtaining protein isolates and concentrates from colostrum

Info

Publication number
WO2001003515A8
WO2001003515A8 PCT/NZ2000/000120 NZ0000120W WO0103515A8 WO 2001003515 A8 WO2001003515 A8 WO 2001003515A8 NZ 0000120 W NZ0000120 W NZ 0000120W WO 0103515 A8 WO0103515 A8 WO 0103515A8
Authority
WO
WIPO (PCT)
Prior art keywords
colostrum
deplete
serum
protein
proteins
Prior art date
Application number
PCT/NZ2000/000120
Other languages
French (fr)
Other versions
WO2001003515A9 (en
WO2001003515A1 (en
Inventor
Peter Graeme Hobman
Robert Philip Boswell
Joanne Campbell Hutchinson
Georgina Aureen Klarwill
Original Assignee
New Zealand Co Operative Dairy
Peter Graeme Hobman
Robert Philip Boswell
Joanne Campbell Hutchinson
Georgina Aureen Klarwill
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by New Zealand Co Operative Dairy, Peter Graeme Hobman, Robert Philip Boswell, Joanne Campbell Hutchinson, Georgina Aureen Klarwill filed Critical New Zealand Co Operative Dairy
Priority to AU57196/00A priority Critical patent/AU5719600A/en
Publication of WO2001003515A1 publication Critical patent/WO2001003515A1/en
Publication of WO2001003515A9 publication Critical patent/WO2001003515A9/en
Publication of WO2001003515A8 publication Critical patent/WO2001003515A8/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23J—PROTEIN COMPOSITIONS FOR FOODSTUFFS; WORKING-UP PROTEINS FOR FOODSTUFFS; PHOSPHATIDE COMPOSITIONS FOR FOODSTUFFS
    • A23J1/00—Obtaining protein compositions for foodstuffs; Bulk opening of eggs and separation of yolks from whites
    • A23J1/20—Obtaining protein compositions for foodstuffs; Bulk opening of eggs and separation of yolks from whites from milk, e.g. casein; from whey
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23C—DAIRY PRODUCTS, e.g. MILK, BUTTER OR CHEESE; MILK OR CHEESE SUBSTITUTES; MAKING THEREOF
    • A23C9/00—Milk preparations; Milk powder or milk powder preparations
    • A23C9/14—Milk preparations; Milk powder or milk powder preparations in which the chemical composition of the milk is modified by non-chemical treatment
    • A23C9/142—Milk preparations; Milk powder or milk powder preparations in which the chemical composition of the milk is modified by non-chemical treatment by dialysis, reverse osmosis or ultrafiltration
    • A23C9/1422—Milk preparations; Milk powder or milk powder preparations in which the chemical composition of the milk is modified by non-chemical treatment by dialysis, reverse osmosis or ultrafiltration by ultrafiltration, microfiltration or diafiltration of milk, e.g. for separating protein and lactose; Treatment of the UF permeate
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23C—DAIRY PRODUCTS, e.g. MILK, BUTTER OR CHEESE; MILK OR CHEESE SUBSTITUTES; MAKING THEREOF
    • A23C9/00—Milk preparations; Milk powder or milk powder preparations
    • A23C9/20—Dietetic milk products not covered by groups A23C9/12 - A23C9/18
    • A23C9/206—Colostrum; Human milk
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/20—Milk; Whey; Colostrum
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/04—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies from milk
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23C—DAIRY PRODUCTS, e.g. MILK, BUTTER OR CHEESE; MILK OR CHEESE SUBSTITUTES; MAKING THEREOF
    • A23C2210/00—Physical treatment of dairy products
    • A23C2210/20—Treatment using membranes, including sterile filtration
    • A23C2210/206—Membrane filtration of a permeate obtained by ultrafiltration, nanofiltration or microfiltration
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/10—Immunoglobulins specific features characterized by their source of isolation or production
    • C07K2317/12—Immunoglobulins specific features characterized by their source of isolation or production isolated from milk

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Food Science & Technology (AREA)
  • Polymers & Plastics (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Water Supply & Treatment (AREA)
  • Zoology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Nutrition Science (AREA)
  • Biophysics (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Cell Biology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Virology (AREA)
  • Molecular Biology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)

Abstract

This invention relates to a method of producing protein isolates and concentrates by microfiltration of colostrum, and the production of products fortified with immunoglobulins. The method involves taking a skim colostrum stream, derived from colostrum by the separation of fat and other particulate and cellular material, or by reconstituting skim colostrum powder and water, and microfiltration of that skim colostrum stream to produce a permeate rich in colostral serum proteins and a serum deplete retentate including an enhanced ratio of casein:whey protein. The invention also relates to a method of producing a colostrum powder deplete in whey proteins from colostrum in which an intermediate permeate from the microfiltration, rich in colostral serum proteins, is concentrated and then mixed back with the serum deplete retentate, the mixture optionally being concentrated before drying to produce a colostrum powder deplete in whey proteins. The invention also includes a colostral serum isolate including a protein content of at least 70 %, a colostrum protein concentrate which is serum deplete and includes an enhanced ratio of casein:whey protein and a colostrum powder deplete in whey proteins.
PCT/NZ2000/000120 1999-07-07 2000-07-07 Method of obtaining protein isolates and concentrates from colostrum WO2001003515A1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU57196/00A AU5719600A (en) 1999-07-07 2000-07-07 Method of obtaining protein isolates and concentrates from colostrum

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
NZ336641 1999-07-07
NZ33664199 1999-07-07

Publications (3)

Publication Number Publication Date
WO2001003515A1 WO2001003515A1 (en) 2001-01-18
WO2001003515A9 WO2001003515A9 (en) 2002-08-29
WO2001003515A8 true WO2001003515A8 (en) 2004-04-29

Family

ID=19927370

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/NZ2000/000120 WO2001003515A1 (en) 1999-07-07 2000-07-07 Method of obtaining protein isolates and concentrates from colostrum

Country Status (4)

Country Link
AR (1) AR024676A1 (en)
AU (1) AU5719600A (en)
UY (1) UY26236A1 (en)
WO (1) WO2001003515A1 (en)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20040000663A (en) * 2002-06-25 2004-01-07 주식회사 렉스진바이오텍 Colostrum fraction containing immune-active material, process for preparation thereof, and food or medical composition containing the same
US20070166447A1 (en) 2002-08-27 2007-07-19 Select Milk Producers, Inc. Dairy compositions and method of making
US7169428B2 (en) 2002-08-27 2007-01-30 Select Milk Producers Inc. Dairy compositions and method of making
US20050181093A1 (en) * 2004-02-18 2005-08-18 Achs Ronald A. Concentrated-protein food product and process
US20060051347A1 (en) 2004-09-09 2006-03-09 Winter Charles M Process for concentration of antibodies and therapeutic products thereof
WO2006039759A1 (en) * 2004-10-15 2006-04-20 Murray Goulburn Co-Operative Co Limited Improved milk powder and method of manufacture
LT5362B (en) 2005-11-02 2006-10-25 Vytautas Fedaravicius Method and device for producing casein
BRPI0911994A2 (en) 2008-05-15 2015-10-20 Health L P W process for the production of a milk fraction enriched with secretory iga, product, and composition.
US9055752B2 (en) 2008-11-06 2015-06-16 Intercontinental Great Brands Llc Shelf-stable concentrated dairy liquids and methods of forming thereof
BR112012009744B1 (en) * 2009-10-28 2018-04-03 Valio Ltd MILK SERUM PROTEIN PRODUCT AND A METHOD FOR PREPARATION
ITMI20092069A1 (en) * 2009-11-25 2011-05-26 Biofer Spa METHOD TO OBTAIN A MIXTURE OF BIOLOGICAL FACTORS ISOLATED BY COLOSTRO AND MIXTURE OF ACTIVE BIOLOGICAL FACTORS DERIVED FROM COLOSTRO.
CN101911976A (en) * 2010-07-30 2010-12-15 生命阳光(广州)营养品有限公司 Milk calcium formula nutritional powder
UA112972C2 (en) 2010-09-08 2016-11-25 Інтерконтінентал Грейт Брендс ЛЛС LIQUID DAIRY CONCENTRATE WITH A HIGH CONTENT OF DRY SUBSTANCES
FI124323B (en) 2011-02-18 2014-06-30 Valio Oy Milk-based product and process for its preparation
EP2762490A1 (en) * 2013-01-31 2014-08-06 DMK Deutsches Milchkontor GmbH Process for obtaining immunoglobulins from colostrum
PT3175238T (en) 2014-07-28 2021-10-20 Nestle Sa Devices and kits for production of personalized, concentrated human milk compositions, and methods of making and using same
CN107115768B (en) * 2017-04-25 2021-02-12 华北电力大学 Preparation method of flue gas dehydration ceramic membrane with fly ash as main raw material
CN111194824B (en) * 2018-11-16 2023-03-03 内蒙古伊利实业集团股份有限公司 Concentrated milk protein liquid and preparation method thereof
EP4003061B1 (en) 2019-07-23 2024-04-24 FrieslandCampina Nederland B.V. Nutritional composition comprising milk fat and immunoglobulin
RU2738745C1 (en) * 2020-10-11 2020-12-16 Общество с ограниченной ответственностью «Победа-1» (ООО «Победа-1») Bacteriologically pure protein product with high content of minor proteins
RU2736646C1 (en) * 2020-10-11 2020-11-19 Общество с ограниченной ответственностью «Победа-1» (ООО «Победа-1») Apparatus for producing a bacteriologically pure protein product with high content of minor proteins
RU2736645C1 (en) * 2020-10-11 2020-11-19 Общество с ограниченной ответственностью «Победа-1» (ООО «Победа-1») Method for producing a bacteriologically pure protein product with high content of minor proteins
CN115715557A (en) * 2022-04-19 2023-02-28 黑龙江省康平生物工程有限责任公司 Method and system for automatically producing bovine colostrum powder and application of preparation thereof in antitumor drugs

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3432718C1 (en) * 1984-09-06 1986-05-22 Biotest Pharma GmbH, 6000 Frankfurt Process for the preparation of a solution of milk and / or colostral immunoglobulins
FR2628973B1 (en) * 1988-03-25 1990-11-16 Gattefosse Ets Sa COSMETIC OR PHARMACEUTICAL COMPOSITION FOR SKIN USE, AND PROCESS FOR THE PREPARATION OF SUCH A COMPOSITION
AU5254790A (en) * 1989-04-06 1990-10-11 Chugai Seiyaku Kabushiki Kaisha Process for preparing a therapeutic agent for rotavirus infection
AU6847894A (en) * 1993-06-23 1995-01-17 Viable Bioproducts Ltd. Method for the improvement of wound healing and compositions therefor
US5707678A (en) * 1995-04-12 1998-01-13 Galagen Inc. Method for microfiltration of milk or colostral whey

Also Published As

Publication number Publication date
WO2001003515A9 (en) 2002-08-29
AU5719600A (en) 2001-01-30
AR024676A1 (en) 2002-10-23
WO2001003515A1 (en) 2001-01-18
UY26236A1 (en) 2000-10-31

Similar Documents

Publication Publication Date Title
WO2001003515A8 (en) Method of obtaining protein isolates and concentrates from colostrum
Rosenberg Current and future applications for membrane processes in the dairy industry
LT2001060A (en) Method for producing cheese and cheese products
AU2011322448B2 (en) Milk product and preparation method
US4341801A (en) Ultrafiltration process for the preparation of cream cheese
Guo Whey protein production, chemistry, functionality, and applications
Guo et al. History of whey production and whey protein manufacturing
DE3264084D1 (en) Process for lactoserum protein recovery, use in the manufacture of cheeses and cheeses obtained
CA2496615A1 (en) Dairy compositions and method of making
IE791260L (en) Whey protein extraction.
US8389039B2 (en) Process for preparing bioactive protein-enriched whey products
AU2012280182B2 (en) Milk-based formulation
ES2032565T3 (en) PROCEDURE TO OBTAIN FROM MILK SERUM CONCENTRATES THAT HAVE A HIGH CONTENT IN ALPHA-LACTALBUMIN.
EP0320152A3 (en) Isolation of an immunoglobulin rich fraction from whey isolation of an immunoglobulin rich fraction from whey
CA2261277A1 (en) A method of producing aseptic consumer milk
US11793211B2 (en) Dairy processing systems and methods
JP3759984B2 (en) Purification of component 3 of milk proteose peptone
FI129799B (en) Buttermilk
US4391837A (en) Process for the manufacture of a liquid, paste or powder whey product simulative of a skin milk product
Henriques et al. Characterization of bovine and ovine WPC obtained by different membrane configuration processes
JPH09266756A (en) Impartment of milky flavor and milky flavor imparter
JPH09266757A (en) Milky flavor imparter and its production
FR2439554A1 (en) High quality protein sepn. from milk - by heating, ultrafiltration and further heating the retentate
SU1145980A1 (en) Method of separating protein from whey
FR2427061A1 (en) Protein esp. for children's diets and cheese mfr. - recovered from whey by heat-treatment and ultra-filtration of denatured protein (NL 13.11.79)

Legal Events

Date Code Title Description
AK Designated states

Kind code of ref document: A1

Designated state(s): AE AG AL AM AT AT AU AZ BA BB BG BR BY BZ CA CH CN CR CU CZ CZ DE DE DK DK DM DZ EE EE ES FI FI GB GD GE GH GM HR HU ID IL IN IS JP KE KG KP KR KZ LC LK LR LS LT LU LV MA MD MG MK MN MW MX MZ NO NZ PL PT RO RU SD SE SG SI SK SK SL TJ TM TR TT TZ UA UG US UZ VN YU ZA ZW

AL Designated countries for regional patents

Kind code of ref document: A1

Designated state(s): GH GM KE LS MW MZ SD SL SZ TZ UG ZW AM AZ BY KG KZ MD RU TJ TM AT BE CH CY DE DK ES FI FR GB GR IE IT LU MC NL PT SE BF BJ CF CG CI CM GA GN GW ML MR NE SN TD TG

121 Ep: the epo has been informed by wipo that ep was designated in this application
DFPE Request for preliminary examination filed prior to expiration of 19th month from priority date (pct application filed before 20040101)
REG Reference to national code

Ref country code: DE

Ref legal event code: 8642

AK Designated states

Kind code of ref document: C2

Designated state(s): AE AG AL AM AT AU AZ BA BB BG BR BY BZ CA CH CN CR CU CZ DE DK DM DZ EE ES FI GB GD GE GH GM HR HU ID IL IN IS JP KE KG KP KR KZ LC LK LR LS LT LU LV MA MD MG MK MN MW MX MZ NO NZ PL PT RO RU SD SE SG SI SK SL TJ TM TR TT TZ UA UG US UZ VN YU ZA ZW

AL Designated countries for regional patents

Kind code of ref document: C2

Designated state(s): GH GM KE LS MW MZ SD SL SZ TZ UG ZW AM AZ BY KG KZ MD RU TJ TM AT BE CH CY DE DK ES FI FR GB GR IE IT LU MC NL PT SE BF BJ CF CG CI CM GA GN GW ML MR NE SN TD TG

COP Corrected version of pamphlet

Free format text: PAGE 18, CLAIMS, ADDED

122 Ep: pct application non-entry in european phase
NENP Non-entry into the national phase in:

Ref country code: JP

CFP Corrected version of a pamphlet front page
CR1 Correction of entry in section i

Free format text: IN PCT GAZETTE 03/2001 DUE TO A TECHNICAL PROBLEMAT THE TIME OF INTERNATIONAL PUBLICATION, SOME INFORMATION WAS MISSING UNDER (81). THE MISSING INFORMATION NOW APPEARS IN THE CORRECTED VERSION