WO2001002031A3 - Traitement anti-calcification cible - Google Patents

Traitement anti-calcification cible Download PDF

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Publication number
WO2001002031A3
WO2001002031A3 PCT/US2000/017606 US0017606W WO0102031A3 WO 2001002031 A3 WO2001002031 A3 WO 2001002031A3 US 0017606 W US0017606 W US 0017606W WO 0102031 A3 WO0102031 A3 WO 0102031A3
Authority
WO
WIPO (PCT)
Prior art keywords
cell
treatments
targeted agents
targeted
calcification
Prior art date
Application number
PCT/US2000/017606
Other languages
English (en)
Other versions
WO2001002031A2 (fr
Inventor
Dan Simionescu
Agneta Simionescu
Jean-Marie Girardot
Marie-Nadia Girardot
Original Assignee
Biomedical Design Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biomedical Design Inc filed Critical Biomedical Design Inc
Priority to AU56397/00A priority Critical patent/AU5639700A/en
Publication of WO2001002031A2 publication Critical patent/WO2001002031A2/fr
Publication of WO2001002031A3 publication Critical patent/WO2001002031A3/fr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2400/00—Materials characterised by their function or physical properties
    • A61L2400/02—Treatment of implants to prevent calcification or mineralisation in vivo

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Dermatology (AREA)
  • Medicinal Chemistry (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Transplantation (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

La présente invention concerne des procédés permettant de conférer aux biomatériaux une résistance accrue à la calcification, grâce à un traitement au moyen d'agents à ciblage cellulaire et/ou à ciblage matriciel. En l'occurrence, on utilise des agents à ciblage cellulaire qui bloquent les canaux calcium, ou qui préviennent l'atteinte oxydative des cellules, et/ou qui inhibent des enzymes. D'autres traitements des biomatériaux permettent d'éliminer des composants de liaison au calcaire issus des cellules, ou cibler des matrices extracellulaire, notamment par un clivage de protéines au moyen du bromure de cyanogène, ou par réduction des liaisons bisulfure donnant des groupes sulfhydryles qui sont ensuite alkylés. Différentes combinaisons de ces traitements permettent également d'augmenter la résistance à la calcification de tissus cardio-vasculaires ayant préalablement subi des traitements de fixation chimique ou d'anti-calcification.
PCT/US2000/017606 1999-07-01 2000-06-27 Traitement anti-calcification cible WO2001002031A2 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU56397/00A AU5639700A (en) 1999-07-01 2000-06-27 Targeted anticalcification treatment

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US14217199P 1999-07-01 1999-07-01
US60/142,171 1999-07-01

Publications (2)

Publication Number Publication Date
WO2001002031A2 WO2001002031A2 (fr) 2001-01-11
WO2001002031A3 true WO2001002031A3 (fr) 2001-12-06

Family

ID=22498818

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2000/017606 WO2001002031A2 (fr) 1999-07-01 2000-06-27 Traitement anti-calcification cible

Country Status (2)

Country Link
AU (1) AU5639700A (fr)
WO (1) WO2001002031A2 (fr)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8900294B2 (en) 2002-01-04 2014-12-02 Colibri Heart Valve Llc Method of controlled release of a percutaneous replacement heart valve
US9119738B2 (en) 2010-06-28 2015-09-01 Colibri Heart Valve Llc Method and apparatus for the endoluminal delivery of intravascular devices

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7078163B2 (en) 2001-03-30 2006-07-18 Medtronic, Inc. Process for reducing mineralization of tissue used in transplantation
US7955788B2 (en) 2003-10-30 2011-06-07 Medtronic, Inc. Bioprosthetic tissue preparation with synthetic hydrogels
AU2011343755A1 (en) 2010-12-14 2013-06-06 Colibri Heart Valve Llc Percutaneously deliverable heart valve including folded membrane cusps with integral leaflets
RU2597564C1 (ru) * 2015-06-17 2016-09-10 Федеральное государственное бюджетное научное учреждение "Научно-исследовательский институт комплексных проблем сердечно-сосудистых заболеваний" (НИИ КПССЗ) Способ прогнозирования риска кальцификации биологических протезов клапанов сердца
WO2019051476A1 (fr) 2017-09-11 2019-03-14 Incubar, LLC Dispositif d'étanchéité destiné à être utilisé comme implant vasculaire de conduit pour réduire l'endofuite

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4753652A (en) * 1984-05-04 1988-06-28 Children's Medical Center Corporation Biomaterial implants which resist calcification
EP0564786A2 (fr) * 1992-02-12 1993-10-13 Lifecell Corporation Procédé pour le traitement et la conservation de tissus à base de collagène pour la transplantation
WO1996013227A1 (fr) * 1994-10-21 1996-05-09 University Of Michigan Tissus bioprothetiques resistants a la calcification et procedes d'obtention
US5558875A (en) * 1994-06-06 1996-09-24 Wang; Su Method of preparing collagenous tissue
US5843182A (en) * 1994-03-14 1998-12-01 Cryolife, Inc. Treated tissue for implantation and methods of preparation

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4753652A (en) * 1984-05-04 1988-06-28 Children's Medical Center Corporation Biomaterial implants which resist calcification
EP0564786A2 (fr) * 1992-02-12 1993-10-13 Lifecell Corporation Procédé pour le traitement et la conservation de tissus à base de collagène pour la transplantation
US5843182A (en) * 1994-03-14 1998-12-01 Cryolife, Inc. Treated tissue for implantation and methods of preparation
US5558875A (en) * 1994-06-06 1996-09-24 Wang; Su Method of preparing collagenous tissue
WO1996013227A1 (fr) * 1994-10-21 1996-05-09 University Of Michigan Tissus bioprothetiques resistants a la calcification et procedes d'obtention

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
HENRY P D: "ANTI-ATHEROSCLEROTIC EFFECTS OF CALCIUM ANTAGONISTS: A BRIEF REVIEW", CLINICAL AND INVESTIGATIVE MEDICINE, vol. 10, no. 6, 1 November 1987 (1987-11-01), pages 601 - 605, XP000604021 *

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8900294B2 (en) 2002-01-04 2014-12-02 Colibri Heart Valve Llc Method of controlled release of a percutaneous replacement heart valve
US9125739B2 (en) 2002-01-04 2015-09-08 Colibri Heart Valve Llc Percutaneous replacement heart valve and a delivery and implantation system
US9186248B2 (en) 2002-01-04 2015-11-17 Colibri Heart Valve Llc Percutaneously implantable replacement heart valve device and method of making same
US9554898B2 (en) 2002-01-04 2017-01-31 Colibri Heart Valve Llc Percutaneous prosthetic heart valve
US9119738B2 (en) 2010-06-28 2015-09-01 Colibri Heart Valve Llc Method and apparatus for the endoluminal delivery of intravascular devices

Also Published As

Publication number Publication date
WO2001002031A2 (fr) 2001-01-11
AU5639700A (en) 2001-01-22

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