WO2001000823A8 - NOVEL ISOFORMS OF THE HUMAN ESTROGEN RECEPTOR-$g(a) - Google Patents

NOVEL ISOFORMS OF THE HUMAN ESTROGEN RECEPTOR-$g(a)

Info

Publication number
WO2001000823A8
WO2001000823A8 PCT/EP2000/005981 EP0005981W WO0100823A8 WO 2001000823 A8 WO2001000823 A8 WO 2001000823A8 EP 0005981 W EP0005981 W EP 0005981W WO 0100823 A8 WO0100823 A8 WO 0100823A8
Authority
WO
WIPO (PCT)
Prior art keywords
estrogen receptor
human estrogen
novel isoforms
novel
isoforms
Prior art date
Application number
PCT/EP2000/005981
Other languages
French (fr)
Other versions
WO2001000823A1 (en
Inventor
Frank Gannon
Stefanie Denger
Gilles Flouriot
Original Assignee
European Molecular Biology Lab Embl
Frank Gannon
Stefanie Denger
Gilles Flouriot
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by European Molecular Biology Lab Embl, Frank Gannon, Stefanie Denger, Gilles Flouriot filed Critical European Molecular Biology Lab Embl
Priority to AU61527/00A priority Critical patent/AU6152700A/en
Publication of WO2001000823A1 publication Critical patent/WO2001000823A1/en
Publication of WO2001000823A8 publication Critical patent/WO2001000823A8/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/72—Receptors; Cell surface antigens; Cell surface determinants for hormones
    • C07K14/721—Steroid/thyroid hormone superfamily, e.g. GR, EcR, androgen receptor, oestrogen receptor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Abstract

There are disclosed polynucleotide sequences encoding novel hER-α splicing variants, the encoded polypeptides, the use thereof, a method for identifying molecules that modulate the activivy of such polypeptides.
PCT/EP2000/005981 1999-06-29 2000-06-27 NOVEL ISOFORMS OF THE HUMAN ESTROGEN RECEPTOR-$g(a) WO2001000823A1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU61527/00A AU6152700A (en) 1999-06-29 2000-06-27 Novel isoforms of the human estrogen receptor-alpha

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT1999MI001433A IT1313552B1 (en) 1999-06-29 1999-06-29 ISOFORMS OF THE HUMAN ESTROGEN ALPHA RECEPTOR
ITMI99A001433 1999-06-29

Publications (2)

Publication Number Publication Date
WO2001000823A1 WO2001000823A1 (en) 2001-01-04
WO2001000823A8 true WO2001000823A8 (en) 2001-06-21

Family

ID=11383245

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP2000/005981 WO2001000823A1 (en) 1999-06-29 2000-06-27 NOVEL ISOFORMS OF THE HUMAN ESTROGEN RECEPTOR-$g(a)

Country Status (3)

Country Link
AU (1) AU6152700A (en)
IT (1) IT1313552B1 (en)
WO (1) WO2001000823A1 (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6617162B2 (en) 2001-12-18 2003-09-09 Isis Pharmaceuticals, Inc. Antisense modulation of estrogen receptor alpha expression
AU1410801A (en) * 1999-11-17 2001-05-30 Compugen Ltd. Variants of alternative splicing
AU2012202805B2 (en) * 2004-03-10 2014-11-27 Creighton University Estrogen receptors and methods of use
US7745230B2 (en) * 2004-03-10 2010-06-29 Creighton University Estrogen receptors and methods of use
TWI350168B (en) 2004-05-07 2011-10-11 Incyte Corp Amido compounds and their use as pharmaceuticals

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1987005049A1 (en) * 1986-02-20 1987-08-27 California Biotechnology Inc. Eucaryotic expression of steroid receptor proteins
CA2302629C (en) * 1997-09-08 2001-02-20 Merck & Co., Inc. Estrogen receptor

Also Published As

Publication number Publication date
ITMI991433A1 (en) 2000-12-29
IT1313552B1 (en) 2002-09-09
ITMI991433A0 (en) 1999-06-29
WO2001000823A1 (en) 2001-01-04
AU6152700A (en) 2001-01-31

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