WO2000077026A1 - 49 proteines secretees humaines - Google Patents

49 proteines secretees humaines Download PDF

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Publication number
WO2000077026A1
WO2000077026A1 PCT/US2000/014973 US0014973W WO0077026A1 WO 2000077026 A1 WO2000077026 A1 WO 2000077026A1 US 0014973 W US0014973 W US 0014973W WO 0077026 A1 WO0077026 A1 WO 0077026A1
Authority
WO
WIPO (PCT)
Prior art keywords
human
seq
sequence
polypeptide
soares
Prior art date
Application number
PCT/US2000/014973
Other languages
English (en)
Other versions
WO2000077026A8 (fr
Inventor
Craig A. Rosen
Steven M. Ruben
George A. Komatsoulis
Original Assignee
Human Genome Sciences, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to CA002383041A priority Critical patent/CA2383041A1/fr
Priority to AU55912/00A priority patent/AU5591200A/en
Priority to JP2001503883A priority patent/JP2003502062A/ja
Priority to EP00941165A priority patent/EP1192176A4/fr
Application filed by Human Genome Sciences, Inc. filed Critical Human Genome Sciences, Inc.
Publication of WO2000077026A1 publication Critical patent/WO2000077026A1/fr
Publication of WO2000077026A8 publication Critical patent/WO2000077026A8/fr
Priority to US10/105,299 priority patent/US7368527B2/en
Priority to US10/670,185 priority patent/US20070015162A1/en
Priority to US10/670,186 priority patent/US20070031842A1/en
Priority to US10/868,184 priority patent/US20070048818A1/en
Priority to US10/994,608 priority patent/US20070048297A1/en
Priority to US11/781,665 priority patent/US20070298491A1/en
Priority to US12/753,401 priority patent/US8410248B2/en
Priority to US13/848,789 priority patent/US20130203164A1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy

Abstract

Cette invention se rapporte à de nouvelles protéines sécrétées humaines et à des acides nucléiques isolés contenant les régions de codage des gènes codant ces protéines. Cette invention se rapporte également à des vecteurs, des cellules hôtes, des anticorps et des procédés de recombinaison permettant de produire des protéines sécrétées humaines; ainsi qu'à des procédés diagnostiques et thérapeutiques servant à diagnostiquer et à traiter des maladies, des troubles et/ou des états liés à ces nouvelles protéines sécrétées humaines.
PCT/US2000/014973 1999-03-12 2000-06-01 49 proteines secretees humaines WO2000077026A1 (fr)

Priority Applications (12)

Application Number Priority Date Filing Date Title
CA002383041A CA2383041A1 (fr) 1999-06-11 2000-06-01 49 proteines secretees humaines
AU55912/00A AU5591200A (en) 1999-06-11 2000-06-01 49 human secreted proteins
JP2001503883A JP2003502062A (ja) 1999-06-11 2000-06-01 ４９個のヒト分泌タンパク質
EP00941165A EP1192176A4 (fr) 1999-06-11 2000-06-01 49 proteines secretees humaines
US10/105,299 US7368527B2 (en) 1999-03-12 2002-03-26 HADDE71 polypeptides
US10/670,185 US20070015162A1 (en) 1999-03-12 2003-09-25 99 human secreted proteins
US10/670,186 US20070031842A1 (en) 1999-03-12 2003-09-25 379 human secreted proteins
US10/868,184 US20070048818A1 (en) 1999-03-12 2004-06-16 Human secreted proteins
US10/994,608 US20070048297A1 (en) 1999-03-12 2004-11-23 Human secreted proteins
US11/781,665 US20070298491A1 (en) 1999-03-12 2007-07-23 Human Secreted Proteins
US12/753,401 US8410248B2 (en) 1999-03-12 2010-04-02 HWBAO62 polypeptides
US13/848,789 US20130203164A1 (en) 1999-03-12 2013-03-22 Human Secreted Proteins

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US13863099P 1999-06-11 1999-06-11
US60/138,630 1999-06-11

Related Parent Applications (2)

Application Number Title Priority Date Filing Date
PCT/US2000/014928 Continuation-In-Part WO2000077237A1 (fr) 1999-03-12 2000-06-01 49 proteines humaines secretees
PCT/US2000/014964 Continuation-In-Part WO2000077023A1 (fr) 1999-03-12 2000-06-01 48 proteines secretees humaines

Related Child Applications (4)

Application Number Title Priority Date Filing Date
PCT/US2000/014928 Continuation-In-Part WO2000077237A1 (fr) 1999-03-12 2000-06-01 49 proteines humaines secretees
PCT/US2000/014964 Continuation-In-Part WO2000077023A1 (fr) 1999-03-12 2000-06-01 48 proteines secretees humaines
US95008301A Continuation-In-Part 1999-03-12 2001-09-12
US95008201A Continuation-In-Part 1999-03-12 2001-09-12

Publications (2)

Publication Number Publication Date
WO2000077026A1 true WO2000077026A1 (fr) 2000-12-21
WO2000077026A8 WO2000077026A8 (fr) 2001-03-29

Family

ID=22482899

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2000/014973 WO2000077026A1 (fr) 1999-03-12 2000-06-01 49 proteines secretees humaines

Country Status (5)

Country Link
EP (1) EP1192176A4 (fr)
JP (1) JP2003502062A (fr)
AU (1) AU5591200A (fr)
CA (1) CA2383041A1 (fr)
WO (1) WO2000077026A1 (fr)

Cited By (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002024913A2 (fr) * 2000-09-25 2002-03-28 Millennium Pharmaceuticals, Inc. 32612, un nouveau transporteur de peptides humain et utilisations de celui-ci
WO2002033096A2 (fr) * 2000-10-16 2002-04-25 Bayer Aktiengesellschaft Regulation de la serine-threonine proteine kinase humaine
US6710170B2 (en) 1999-09-10 2004-03-23 Corixa Corporation Compositions and methods for the therapy and diagnosis of ovarian cancer
EP1489095A1 (fr) * 2000-06-02 2004-12-22 Genentech Inc. Polypeptide, acides nucléiques le codant, et leur utilisation pour le diagnostic du cancer
US7144990B2 (en) 2001-06-01 2006-12-05 Genentech, Inc. Antibody to a polypeptide overexpressed in tumors
WO2008103962A3 (fr) * 2007-02-22 2008-12-18 Genentech Inc Méthode de détection d'une maladie intestinale inflammatoire
US7598051B2 (en) 1999-09-10 2009-10-06 Corixa Corporation Compositions and methods for the therapy and diagnosis of ovarian cancer
US8183347B2 (en) 2006-03-17 2012-05-22 Genentech, Inc. Anti-TAT226 antibodies and immunoconjugates
RU2532228C2 (ru) * 2009-01-21 2014-10-27 Массачусетс Инститьют Оф Текнолоджи Композиции и способы, используемые для оценки цитотоксичности отдельных клеток
US20150071905A1 (en) * 2012-01-17 2015-03-12 The Board Of Trustees Of The Leland Stanford Junior University High Affinity Sirp-Alpha Reagents
US10125183B2 (en) * 2015-06-29 2018-11-13 Curacle Co., Ltd. Decoy peptides inhibiting binding of AMIGO2 and 3-phosphoinositide-dependent kinase 1
CN109030796A (zh) * 2018-06-26 2018-12-18 山东卓越生物技术股份有限公司 医疗测试卡片及其测试装置
US10259859B2 (en) 2015-08-07 2019-04-16 ALX Oncology Inc. Constructs having a SIRP-α domain or variant thereof
US11613564B2 (en) 2019-05-31 2023-03-28 ALX Oncology Inc. Methods of treating cancer

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP7193058B2 (ja) * 2018-08-08 2022-12-20 イミューンオンコ バイオファーマシューティカルズ （シャンハイ） インコーポレイテッド Ｃｄ４７およびｈｅｒ２を標的とする組換え二機能性タンパク質

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1998045437A2 (fr) * 1997-04-10 1998-10-15 Genetics Institute, Inc. MARQUEURS SECRETES DE SEQUENCE EXPRIMEE (sEST)

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2291260A1 (fr) * 1997-06-06 1998-12-10 Human Genome Sciences, Inc. 207 proteines secretees par l'etre humain

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1998045437A2 (fr) * 1997-04-10 1998-10-15 Genetics Institute, Inc. MARQUEURS SECRETES DE SEQUENCE EXPRIMEE (sEST)

Non-Patent Citations (5)

* Cited by examiner, † Cited by third party
Title
DATABASE GENBANK [online] 18 December 1997 (1997-12-18), "especially bases 1-622", XP002908797, Database accession no. AA780275 *
DATABASE GENBANK [online] June 1999 (1999-06-01), "especially bases 1-243", XP002938803, Database accession no. Q9Y4S1 *
DATABASE GENEMBL [online] 16 June 1999 (1999-06-16), "especially bases 6-2153", XP002938801, Database accession no. AL080121 *
DATABASE GENEMBL [online] 28 August 1999 (1999-08-28), "especially bases 150598-151904", XP002938802, Database accession no. AC009675 *
See also references of EP1192176A4 *

Cited By (35)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7598051B2 (en) 1999-09-10 2009-10-06 Corixa Corporation Compositions and methods for the therapy and diagnosis of ovarian cancer
US6710170B2 (en) 1999-09-10 2004-03-23 Corixa Corporation Compositions and methods for the therapy and diagnosis of ovarian cancer
US7985843B2 (en) 1999-09-10 2011-07-26 Corixa Corporation Compositions and methods for the therapy and diagnosis of ovarian cancer
EP1489095A1 (fr) * 2000-06-02 2004-12-22 Genentech Inc. Polypeptide, acides nucléiques le codant, et leur utilisation pour le diagnostic du cancer
WO2002024913A3 (fr) * 2000-09-25 2003-05-15 Millennium Pharm Inc 32612, un nouveau transporteur de peptides humain et utilisations de celui-ci
WO2002024913A2 (fr) * 2000-09-25 2002-03-28 Millennium Pharmaceuticals, Inc. 32612, un nouveau transporteur de peptides humain et utilisations de celui-ci
WO2002033096A2 (fr) * 2000-10-16 2002-04-25 Bayer Aktiengesellschaft Regulation de la serine-threonine proteine kinase humaine
WO2002033096A3 (fr) * 2000-10-16 2002-09-19 Bayer Ag Regulation de la serine-threonine proteine kinase humaine
US7150976B2 (en) 2000-10-16 2006-12-19 Bayer Healthcare Ag Regulation of human serine-threonine protein kinase
US7157558B2 (en) 2001-06-01 2007-01-02 Genentech, Inc. Polypeptide encoded by a polynucleotide overexpresses in tumors
US7144990B2 (en) 2001-06-01 2006-12-05 Genentech, Inc. Antibody to a polypeptide overexpressed in tumors
US7476723B2 (en) 2001-06-01 2009-01-13 Genentech, Inc. Immunoconjugates and antibodies to PRO9917
US7208316B2 (en) 2001-06-01 2007-04-24 Genentech, Inc. Polynucleotide overexpressed in tumors
US7807385B2 (en) 2001-06-01 2010-10-05 Genentech, Inc. Method of detecting PRO9917
USRE41888E1 (en) 2001-06-01 2010-10-26 Genentech, Inc. Polynucleotide overexpressed in tumors
US8183347B2 (en) 2006-03-17 2012-05-22 Genentech, Inc. Anti-TAT226 antibodies and immunoconjugates
US9109035B2 (en) 2006-03-17 2015-08-18 Genentech, Inc. Anti-TAT226 antibodies and immunoconjugates
US9675707B2 (en) 2006-03-17 2017-06-13 Genentech, Inc. Anti-TAT226 antibodies and immunoconjugates
US7875431B2 (en) 2007-02-22 2011-01-25 Genentech, Inc. Methods for detecting inflammatory bowel disease
CN101663407B (zh) * 2007-02-22 2017-08-08 健泰科生物技术公司 用于检测炎性肠病的方法
EP2436781A1 (fr) * 2007-02-22 2012-04-04 Genentech, Inc. Méthode de détection d'une maladie intestinale inflammatoire
US8257923B2 (en) 2007-02-22 2012-09-04 Genetech, Inc. Methods for detecting inflammatory bowel disease
RU2502806C2 (ru) * 2007-02-22 2013-12-27 Дженентек, Инк. Способы выявления воспалительного заболевания кишечника
WO2008103962A3 (fr) * 2007-02-22 2008-12-18 Genentech Inc Méthode de détection d'une maladie intestinale inflammatoire
RU2532228C2 (ru) * 2009-01-21 2014-10-27 Массачусетс Инститьют Оф Текнолоджи Композиции и способы, используемые для оценки цитотоксичности отдельных клеток
US20150071905A1 (en) * 2012-01-17 2015-03-12 The Board Of Trustees Of The Leland Stanford Junior University High Affinity Sirp-Alpha Reagents
US9944911B2 (en) * 2012-01-17 2018-04-17 The Board Of Trustees Of The Leland Stanford Junior University High affinity Sirp-alpha reagents and methods of using
US11208481B2 (en) 2012-01-17 2021-12-28 The Board Of Trustees Of The Leland Stanford Junior University High affinity SIRP-alpha reagents and methods of using
US10125183B2 (en) * 2015-06-29 2018-11-13 Curacle Co., Ltd. Decoy peptides inhibiting binding of AMIGO2 and 3-phosphoinositide-dependent kinase 1
US10259859B2 (en) 2015-08-07 2019-04-16 ALX Oncology Inc. Constructs having a SIRP-α domain or variant thereof
US10696730B2 (en) 2015-08-07 2020-06-30 ALX Oncology Inc. Constructs having a SIRP-alpha domain or variant thereof
US11208459B2 (en) 2015-08-07 2021-12-28 ALX Oncology Inc. Constructs having a SIRP-alpha domain or variant thereof
US11639376B2 (en) 2015-08-07 2023-05-02 ALX Oncology Inc. Constructs having a SIRP-α domain or variant thereof
CN109030796A (zh) * 2018-06-26 2018-12-18 山东卓越生物技术股份有限公司 医疗测试卡片及其测试装置
US11613564B2 (en) 2019-05-31 2023-03-28 ALX Oncology Inc. Methods of treating cancer

Also Published As

Publication number Publication date
CA2383041A1 (fr) 2000-12-21
AU5591200A (en) 2001-01-02
JP2003502062A (ja) 2003-01-21
EP1192176A1 (fr) 2002-04-03
EP1192176A4 (fr) 2003-03-05
WO2000077026A8 (fr) 2001-03-29

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