WO2000073270A8 - Remedes traitant les maladies paradontales - Google Patents

Remedes traitant les maladies paradontales

Info

Publication number
WO2000073270A8
WO2000073270A8 PCT/JP2000/003483 JP0003483W WO0073270A8 WO 2000073270 A8 WO2000073270 A8 WO 2000073270A8 JP 0003483 W JP0003483 W JP 0003483W WO 0073270 A8 WO0073270 A8 WO 0073270A8
Authority
WO
WIPO (PCT)
Prior art keywords
hydrogen
periodontal diseases
carboxyl
remedies
substituted
Prior art date
Application number
PCT/JP2000/003483
Other languages
English (en)
Japanese (ja)
Other versions
WO2000073270A1 (fr
Inventor
Kenji Matsushita
Takahisa Imamura
Ikuro Maruyama
Munehiro Tomikawa
Original Assignee
Daiichi Seiyaku Co
Kenji Matsushita
Takahisa Imamura
Ikuro Maruyama
Munehiro Tomikawa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Daiichi Seiyaku Co, Kenji Matsushita, Takahisa Imamura, Ikuro Maruyama, Munehiro Tomikawa filed Critical Daiichi Seiyaku Co
Priority to AU51028/00A priority Critical patent/AU5102800A/en
Publication of WO2000073270A1 publication Critical patent/WO2000073270A1/fr
Publication of WO2000073270A8 publication Critical patent/WO2000073270A8/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D207/10—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/12—Oxygen or sulfur atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

L'invention porte sur des médicaments préventifs ou curatifs des maladies paradontales contenant comme principe actif des composés de formule générale (1) ou leurs sels et susceptibles de traiter efficacement différentes maladies paradontales telles que la parodontite. Dans la formule (1), R1 est H, ou analogue, R2 est H, alkyle inférieur, ou analogues, R3 est H, carboxyle, ou analogues, R4 est H, halogéno, ou analogues, A est C¿1?-C4 alkylène facultativement substitué par l'un de deux éléments choisis parmi hydroxyalkyle, carboxyle, alkoxycarbonyle ou analogue, X est une liaison simple, oxygène, ou analogue, et Y est un groupe hétérocyclique saturé ou non facultativement substitué à cinq ou six éléments, ou analogue.
PCT/JP2000/003483 1999-05-31 2000-05-31 Remedes traitant les maladies paradontales WO2000073270A1 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU51028/00A AU5102800A (en) 1999-05-31 2000-05-31 Remedies for periodontal diseases

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP15172199 1999-05-31
JP11/151721 1999-05-31

Publications (2)

Publication Number Publication Date
WO2000073270A1 WO2000073270A1 (fr) 2000-12-07
WO2000073270A8 true WO2000073270A8 (fr) 2001-03-01

Family

ID=15524843

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/JP2000/003483 WO2000073270A1 (fr) 1999-05-31 2000-05-31 Remedes traitant les maladies paradontales

Country Status (2)

Country Link
AU (1) AU5102800A (fr)
WO (1) WO2000073270A1 (fr)

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2629884A1 (de) * 1975-07-04 1977-01-20 Gaba Ag Mund- und zahnpflegemittel
ZA928276B (en) * 1991-10-31 1993-05-06 Daiichi Seiyaku Co Aromatic amidine derivates and salts thereof.
JPH06345360A (ja) * 1993-06-02 1994-12-20 Fujita Corp 仮設昇降装置
JPH07267839A (ja) * 1994-03-30 1995-10-17 Sunstar Inc 口腔粘膜付着性軟膏組成物
JPH0820532A (ja) * 1994-07-05 1996-01-23 Dai Ichi Seiyaku Co Ltd 抗膵炎剤
WO1999024407A1 (fr) * 1997-11-10 1999-05-20 Array Biopharma, Inc. Composes inhibant l'activite de la tryptase

Also Published As

Publication number Publication date
AU5102800A (en) 2000-12-18
WO2000073270A1 (fr) 2000-12-07

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