WO2000071114A8 - Salts of cis-[4-cyano-4-(3-cyclopentyloxy-4-methoxyphenyl)cyclohexan-1-carboxylate] - Google Patents

Salts of cis-[4-cyano-4-(3-cyclopentyloxy-4-methoxyphenyl)cyclohexan-1-carboxylate]

Info

Publication number
WO2000071114A8
WO2000071114A8 PCT/US2000/014855 US0014855W WO0071114A8 WO 2000071114 A8 WO2000071114 A8 WO 2000071114A8 US 0014855 W US0014855 W US 0014855W WO 0071114 A8 WO0071114 A8 WO 0071114A8
Authority
WO
WIPO (PCT)
Prior art keywords
cyclohexan
cyclopentyloxy
methoxyphenyl
carboxylate
cis
Prior art date
Application number
PCT/US2000/014855
Other languages
French (fr)
Other versions
WO2000071114A1 (en
Inventor
Guisha Kris Huang
Original Assignee
Smithkline Beecham Corp
Guisha Kris Huang
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to CA002375543A priority Critical patent/CA2375543A1/en
Priority to IL14621300A priority patent/IL146213A0/en
Priority to MXPA01012048A priority patent/MXPA01012048A/en
Priority to NZ515169A priority patent/NZ515169A/en
Priority to PL00351945A priority patent/PL351945A1/en
Priority to KR1020017015036A priority patent/KR20020010669A/en
Priority to EP20000937937 priority patent/EP1194142A4/en
Priority to BR0010483-3A priority patent/BR0010483A/en
Application filed by Smithkline Beecham Corp, Guisha Kris Huang filed Critical Smithkline Beecham Corp
Priority to AU53049/00A priority patent/AU5304900A/en
Priority to JP2000619421A priority patent/JP2003500356A/en
Publication of WO2000071114A1 publication Critical patent/WO2000071114A1/en
Publication of WO2000071114A8 publication Critical patent/WO2000071114A8/en
Priority to NO20015699A priority patent/NO20015699L/en
Priority to HK02106898.8A priority patent/HK1046630A1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C261/00—Derivatives of cyanic acid
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00—Carboxylic acid nitriles
    • C07C255/45—Carboxylic acid nitriles having cyano groups bound to carbon atoms of rings other than six-membered aromatic rings
    • C07C255/46—Carboxylic acid nitriles having cyano groups bound to carbon atoms of rings other than six-membered aromatic rings to carbon atoms of non-condensed rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pulmonology (AREA)
  • Immunology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

This invention relates to salts of cis-[4-cyano-4-(3-cyclopentyloxy-4-methoxyphenyl)cyclohexan-1-carboxylate].
PCT/US2000/014855 1999-05-25 2000-05-24 Salts of cis-[4-cyano-4-(3-cyclopentyloxy-4-methoxyphenyl)cyclohexan-1-carboxylate] WO2000071114A1 (en)

Priority Applications (12)

Application Number Priority Date Filing Date Title
EP20000937937 EP1194142A4 (en) 1999-05-25 2000-05-24 Salts of cis -4-cyano-4-(3-cyclopentyloxy-4-methoxyphenyl) cyclohexan-1-carboxylate!
MXPA01012048A MXPA01012048A (en) 1999-05-25 2000-05-24 Salts of cis.
NZ515169A NZ515169A (en) 1999-05-25 2000-05-24 Salts of cis-[4-cyano-4-(3-cyclopentyloxy-4-methoxyphenyl) cyclohexan-1-carboxylate] and pharmaceuticals thereof
PL00351945A PL351945A1 (en) 1999-05-25 2000-05-24 Salts of cis [4-cyano-4-(cyclopentyloxy-4-methoxyphenyl) cyclohexan-1-carboxylan]
KR1020017015036A KR20020010669A (en) 1999-05-25 2000-05-24 Salts of Cis-[4-Cyano-4-(3-Cyclopentyloxy-4-Methoxyphenyl) Cyclohexan-1-Carboxylate]
CA002375543A CA2375543A1 (en) 1999-05-25 2000-05-24 Salts of cis-¬4-cyano-4-(3-cyclopentyloxy-4-methoxyphenyl)cyclohexan-1-carboxylate|
BR0010483-3A BR0010483A (en) 1999-05-25 2000-05-24 Cis- [4-cyano-4- (3-cyclopentyloxy-4-methoxyphenyl) cyclohexan-1-carboxylate salts]
IL14621300A IL146213A0 (en) 1999-05-25 2000-05-24 Sales of cis-[4-cyano-4-(3-cyclopentyloxy-4-methoxyphenyl) cyclohexan-1-carboxilate
AU53049/00A AU5304900A (en) 1999-05-25 2000-05-24 Salts of CIS-(4-cyano-4-(3-cyclopentyloxy-4-methoxyphenyl) cyclohexan-1-carboxylate)
JP2000619421A JP2003500356A (en) 1999-05-25 2000-05-24 Salt of cis- [4-cyano-4- (3-cyclopentyloxy-4-methoxyphenyl) cyclohexane-1-carboxylic acid]
NO20015699A NO20015699L (en) 1999-05-25 2001-11-22 Salts of cis- (4-cyano-4- (3-cyclopentyloxy-4-methoxyphenyl) cyclohexane-1-carboxylate)
HK02106898.8A HK1046630A1 (en) 1999-05-25 2002-09-20 Salts of cis-[4-cyano-4-(3-cyclopentyloxy-4-methoxyphenyl)cyclohexan-1-carboxylate

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US13573299P 1999-05-25 1999-05-25
US60/135,732 1999-05-25

Publications (2)

Publication Number Publication Date
WO2000071114A1 WO2000071114A1 (en) 2000-11-30
WO2000071114A8 true WO2000071114A8 (en) 2001-05-25

Family

ID=22469405

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2000/014855 WO2000071114A1 (en) 1999-05-25 2000-05-24 Salts of cis-[4-cyano-4-(3-cyclopentyloxy-4-methoxyphenyl)cyclohexan-1-carboxylate]

Country Status (20)

Country Link
EP (1) EP1194142A4 (en)
JP (1) JP2003500356A (en)
KR (1) KR20020010669A (en)
CN (1) CN1351491A (en)
AR (1) AR024076A1 (en)
AU (1) AU5304900A (en)
BR (1) BR0010483A (en)
CA (1) CA2375543A1 (en)
CO (1) CO5170527A1 (en)
CZ (1) CZ20014186A3 (en)
HK (1) HK1046630A1 (en)
HU (1) HUP0201265A3 (en)
IL (1) IL146213A0 (en)
MX (1) MXPA01012048A (en)
NO (1) NO20015699L (en)
NZ (1) NZ515169A (en)
PL (1) PL351945A1 (en)
TR (1) TR200103238T2 (en)
WO (1) WO2000071114A1 (en)
ZA (1) ZA200109624B (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001043692A2 (en) * 1999-12-15 2001-06-21 Smithkline Beecham Corporation SALTS OF Cis-4-CYANO-4-[3-(CYCLOPENTYLOXY)-4-METHOXYPHENYL]CYCLOHEXANE-1-CARBOXYLIC ACID
JP2015510947A (en) * 2012-03-22 2015-04-13 トランステック・ファーマ，エルエルシー Tris (hydroxymethyl) aminomethane salt of small molecule GLP1R agonist and pharmaceutical composition and use thereof

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SK279958B6 (en) * 1992-04-02 1999-06-11 Smithkline Beecham Corporation Compounds exhibiting anti-allergic and anti-inflammatory properties, pharmaceutical composition them containing and their use
UY25338A1 (en) * 1998-01-07 2001-08-27 Smithkline Beecham Corp METHOD FOR TREATING COPD
WO2001043692A2 (en) * 1999-12-15 2001-06-21 Smithkline Beecham Corporation SALTS OF Cis-4-CYANO-4-[3-(CYCLOPENTYLOXY)-4-METHOXYPHENYL]CYCLOHEXANE-1-CARBOXYLIC ACID

Also Published As

Publication number Publication date
CA2375543A1 (en) 2000-11-30
CN1351491A (en) 2002-05-29
HUP0201265A3 (en) 2003-03-28
MXPA01012048A (en) 2002-05-06
NO20015699D0 (en) 2001-11-22
EP1194142A4 (en) 2002-10-25
TR200103238T2 (en) 2002-02-21
AU5304900A (en) 2000-12-12
NO20015699L (en) 2001-11-22
HK1046630A1 (en) 2003-01-24
EP1194142A1 (en) 2002-04-10
ZA200109624B (en) 2002-09-11
WO2000071114A1 (en) 2000-11-30
JP2003500356A (en) 2003-01-07
CZ20014186A3 (en) 2002-04-17
KR20020010669A (en) 2002-02-04
BR0010483A (en) 2002-02-13
AR024076A1 (en) 2002-09-04
PL351945A1 (en) 2003-07-14
CO5170527A1 (en) 2002-06-27
NZ515169A (en) 2003-05-30
IL146213A0 (en) 2002-07-25
HUP0201265A2 (en) 2002-08-28

Similar Documents

Publication Publication Date Title
ZA991933B (en) Remineralization of teeth.
AU2001263171A1 (en) Antisense modulation of tert expression
AU2002361149A1 (en) Set of teeth
AU2002366955A1 (en) Antisense modulation of mucin 1, transmembrane expression
WO2002067886A3 (en) Skin composition
AU2002345455A1 (en) Epoxide stabilization of fluorophosphite-metal catalyst system
WO2003037863A3 (en) Substituted indoles, method for production and use thereof for the inhibition of pain
CA2362698A1 (en) Resorcinol derivatives
AU2002366788A1 (en) Antisense modulation of ship-1 expression
AU2002318139A1 (en) Antisense modulation of src-c expression
WO2002102340A3 (en) Use of carnitine and/or one or more acyl-carnitines for producing cosmetic or dermatological preparations
AU2002247105A1 (en) Stabilization of hypoallergenic, hyperdigestible previously reduced proteins
AU2002357102A1 (en) Antisense modulation of cd36l1 expression
EP1550667A4 (en) Tyrosinase activity controlling agents, process for producing the same and external preparations containing the same
WO2000071114A8 (en) Salts of cis-[4-cyano-4-(3-cyclopentyloxy-4-methoxyphenyl)cyclohexan-1-carboxylate]
WO1998059005A3 (en) Use of polycarbonates containing iodine phenyl carbonate for producing special shaped parts
AU2002254502A1 (en) Pak2: modulators of lymphocyte activation
MXPA03010498A (en) Process for the preparation of imipenem.
AU2002327440A1 (en) Treatment of type i diabetes
AU2002322551A1 (en) Antisense modulation of rip2 expression
AU2002352153A1 (en) Instant emulsion
ZA200210361B (en) Method of administering bishosphonates.
AU7756900A (en) Treatment of chemical hydrolysates
AU2002353026A1 (en) Antisense modulation of nod1 expression
AU2003296499A1 (en) Modulation of ppar-alpha expression

Legal Events

Date Code Title Description
WWE Wipo information: entry into national phase

Ref document number: 00807893.9

Country of ref document: CN

AK Designated states

Kind code of ref document: A1

Designated state(s): AE AG AL AU BA BB BG BR CA CN CZ DZ EE GE GH GM HR HU ID IL IN IS JP KP KR LC LK LR LT LV MA MG MK MN MX MZ NO NZ PL RO SG SI SK SL TR TT TZ UA US UZ VN YU ZA

AL Designated countries for regional patents

Kind code of ref document: A1

Designated state(s): GH GM KE LS MW MZ SD SL SZ TZ UG ZW AM AZ BY KG KZ MD RU TJ TM AT BE CH CY DE DK ES FI FR GB GR IE IT LU MC NL PT SE BF BJ CF CG CI CM GA GN GW ML MR NE SN TD TG

121 Ep: the epo has been informed by wipo that ep was designated in this application
DFPE Request for preliminary examination filed prior to expiration of 19th month from priority date (pct application filed before 20040101)
AK Designated states

Kind code of ref document: C1

Designated state(s): AE AG AL AU BA BB BG BR CA CN CZ DZ EE GE GH GM HR HU ID IL IN IS JP KP KR LC LK LR LT LV MA MG MK MN MX MZ NO NZ PL RO SG SI SK SL TR TT TZ UA US UZ VN YU ZA

AL Designated countries for regional patents

Kind code of ref document: C1

Designated state(s): GH GM KE LS MW MZ SD SL SZ TZ UG ZW AM AZ BY KG KZ MD RU TJ TM AT BE CH CY DE DK ES FI FR GB GR IE IT LU MC NL PT SE BF BJ CF CG CI CM GA GN GW ML MR NE SN TD TG

CFP Corrected version of a pamphlet front page

Free format text: UNDER (54) PUBLISHED TITLE REPLACED BY CORRECT TITLE AND UNDER (57) PUBLISHED ABSTRACT REPLACED BY CORRECT ABSTRACT

WWE Wipo information: entry into national phase

Ref document number: 515169

Country of ref document: NZ

WWE Wipo information: entry into national phase

Ref document number: 53049/00

Country of ref document: AU

WWE Wipo information: entry into national phase

Ref document number: IN/PCT/2001/01377/MU

Country of ref document: IN

WWE Wipo information: entry into national phase

Ref document number: 2000937937

Country of ref document: EP

Ref document number: 2001/03238

Country of ref document: TR

WWE Wipo information: entry into national phase

Ref document number: 10048573

Country of ref document: US

WWE Wipo information: entry into national phase

Ref document number: PV2001-4186

Country of ref document: CZ

WWE Wipo information: entry into national phase

Ref document number: 2001/09624

Country of ref document: ZA

Ref document number: 200109624

Country of ref document: ZA

WWE Wipo information: entry into national phase

Ref document number: PA/a/2001/012048

Country of ref document: MX

WWE Wipo information: entry into national phase

Ref document number: 1020017015036

Country of ref document: KR

ENP Entry into the national phase

Ref document number: 2375543

Country of ref document: CA

Kind code of ref document: A

Ref document number: 2000 619421

Country of ref document: JP

Kind code of ref document: A

WWP Wipo information: published in national office

Ref document number: 1020017015036

Country of ref document: KR

WWP Wipo information: published in national office

Ref document number: 2000937937

Country of ref document: EP

WWP Wipo information: published in national office

Ref document number: PV2001-4186

Country of ref document: CZ

WWW Wipo information: withdrawn in national office

Ref document number: 2000937937

Country of ref document: EP

WWW Wipo information: withdrawn in national office

Ref document number: 1020017015036

Country of ref document: KR

WWR Wipo information: refused in national office

Ref document number: PV2001-4186

Country of ref document: CZ