WO2000070343A3 - G-protein coupled receptor based biosensors and sense replication systems - Google Patents

G-protein coupled receptor based biosensors and sense replication systems Download PDF

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Publication number
WO2000070343A3
WO2000070343A3 PCT/US2000/013160 US0013160W WO0070343A3 WO 2000070343 A3 WO2000070343 A3 WO 2000070343A3 US 0013160 W US0013160 W US 0013160W WO 0070343 A3 WO0070343 A3 WO 0070343A3
Authority
WO
WIPO (PCT)
Prior art keywords
coupled receptor
protein coupled
replication systems
based biosensors
receptor based
Prior art date
Application number
PCT/US2000/013160
Other languages
French (fr)
Other versions
WO2000070343A2 (en
Inventor
Luke V Schneider
William F Stahl Iv
Original Assignee
Repliscent Inc
Luke V Schneider
William F Stahl Iv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Repliscent Inc, Luke V Schneider, William F Stahl Iv filed Critical Repliscent Inc
Priority to AU48476/00A priority Critical patent/AU4847600A/en
Publication of WO2000070343A2 publication Critical patent/WO2000070343A2/en
Publication of WO2000070343A3 publication Critical patent/WO2000070343A3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L9/00—Disinfection, sterilisation or deodorisation of air
    • A61L9/015—Disinfection, sterilisation or deodorisation of air using gaseous or vaporous substances, e.g. ozone
    • A61L9/04—Disinfection, sterilisation or deodorisation of air using gaseous or vaporous substances, e.g. ozone using substances evaporated in the air without heating
    • A61L9/12—Apparatus, e.g. holders, therefor
    • A61L9/125—Apparatus, e.g. holders, therefor emanating multiple odours
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/566—Immunoassay; Biospecific binding assay; Materials therefor using specific carrier or receptor proteins as ligand binding reagents where possible specific carrier or receptor proteins are classified with their target compounds

Abstract

G-protein coupled receptor (GPCR) based sensors and sense replication systems are described. Methods for detecting and discriminating a stimulus corresponding to, or capable of mimicking and/or replacing a G-protein signal transduction system; and methods for mapping, transmitting and reproducing a selected stimulus at a remote location are described. The invention is useful in the electronic, telecommunications and entertainment industries, chemical (including contraband detection, food, flavors and fragrances) biological, medical and diagnostic techniques, as well as for drug discovery.
PCT/US2000/013160 1999-05-14 2000-05-11 G-protein coupled receptor based biosensors and sense replication systems WO2000070343A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU48476/00A AU4847600A (en) 1999-05-14 2000-05-11 G-protein coupled receptor (gpcr) based biosensors and sense replication systems

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US13432599P 1999-05-14 1999-05-14
US60/134,325 1999-05-14
US19165300P 2000-03-23 2000-03-23
US60/191,653 2000-03-23

Publications (2)

Publication Number Publication Date
WO2000070343A2 WO2000070343A2 (en) 2000-11-23
WO2000070343A3 true WO2000070343A3 (en) 2001-04-05

Family

ID=26832215

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2000/013160 WO2000070343A2 (en) 1999-05-14 2000-05-11 G-protein coupled receptor based biosensors and sense replication systems

Country Status (2)

Country Link
AU (1) AU4847600A (en)
WO (1) WO2000070343A2 (en)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2841081A1 (en) * 2002-06-14 2003-12-19 Jacques Fdeda Multimedia audiovisual/information artificial odour broadcast/creation having compressed audio/visual digital signal having digital odour representation setting off multimedia odour cartridges disseminated pipes/ventilator
US8263375B2 (en) 2002-12-20 2012-09-11 Acea Biosciences Dynamic monitoring of activation of G-protein coupled receptor (GPCR) and receptor tyrosine kinase (RTK) in living cells using real-time microelectronic cell sensing technology
US7560269B2 (en) 2002-12-20 2009-07-14 Acea Biosciences, Inc. Real time electronic cell sensing system and applications for cytotoxicity profiling and compound assays
US10539523B2 (en) 2002-12-20 2020-01-21 Acea Biosciences, Inc. System and method for monitoring cardiomyocyte beating, viability, morphology, and electrophysiological properties
US11346797B2 (en) 2002-12-20 2022-05-31 Agilent Technologies, Inc. System and method for monitoring cardiomyocyte beating, viability, morphology and electrophysiological properties
US10215748B2 (en) 2002-12-20 2019-02-26 Acea Biosciences, Inc. Using impedance-based cell response profiling to identify putative inhibitors for oncogene addicted targets or pathways
US10551371B2 (en) 2003-11-10 2020-02-04 Acea Biosciences, Inc. System and method for monitoring cardiomyocyte beating, viability and morphology and for screening for pharmacological agents which may induce cardiotoxicity or modulate cardiomyocyte function
WO2004058974A1 (en) * 2002-12-27 2004-07-15 Actar Ab A method of drug screening to select agonists or antagonists of g protein coupled receptors (gpcr).
CA2550274A1 (en) 2003-11-12 2005-05-26 Acea Biosciences, Inc. Real time electronic cell sensing systems and applications for cell-based assays
EP1773980B1 (en) * 2004-08-04 2015-07-01 Acea Biosciences, Inc. Method for assaying for natural killer, cytotoxic t- lymphocyte and neutrophil-mediated killing of target cells using real-time microelectronic cell sensing technology
JP4842400B2 (en) 2007-03-22 2011-12-21 ヘプテアズ・セラピューティクス・リミテッド G protein-coupled receptor mutant and selection method thereof
GB0724860D0 (en) 2007-12-20 2008-01-30 Heptares Therapeutics Ltd Screening
WO2009137440A1 (en) 2008-05-05 2009-11-12 Acea Biosciences, Inc. Label-free monitoring of excitation-contraction coupling and excitable cells using impedance based systems with millisecond time resolution
WO2011146531A1 (en) 2010-05-18 2011-11-24 Acea Biosciences, Inc Data analysis of impedance-based cardiomyocyte-beating signals as detected on real-time cell analysis (rtca) cardio instruments
US10174101B2 (en) 2011-08-10 2019-01-08 Heptares Therapeutics Limited Stable proteins
EP2856161B1 (en) 2012-06-01 2018-04-18 Heptares Therapeutics Limited Assays
US11092599B2 (en) 2016-02-24 2021-08-17 Aromyx Corporation Biosensor for detecting smell, scent, and taste
EP3589299A4 (en) 2017-03-03 2021-01-13 ACEA Biosciences, Inc. METHODS AND SYSTEMS FOR FUNCTIONAL MATURATION OF iPSC AND ESC DERIVED CARDIOMYOCYTES
US10209239B1 (en) * 2017-08-16 2019-02-19 Aromyx Corporation Method of making an aromagraph comprising ectopic olfactory receptors
US20190194573A1 (en) * 2017-12-21 2019-06-27 Aromyx Corporation Scent, Smell and Odor Creation from an Aromagraph
JP7467378B2 (en) 2021-03-18 2024-04-15 株式会社東芝 Chemical sensor, method and device for detecting target substance

Citations (3)

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Publication number Priority date Publication date Assignee Title
JPH0755742A (en) * 1993-08-18 1995-03-03 Sharp Corp Recording and reproducing device for odor
WO1999016476A1 (en) * 1997-10-01 1999-04-08 Perex Agorreta Francisco Javie Device for reproducing or synthetising odors or aromas
WO1999038102A1 (en) * 1998-01-23 1999-07-29 Bala Narayanaswamy Olfactory emitting system

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0755742A (en) * 1993-08-18 1995-03-03 Sharp Corp Recording and reproducing device for odor
WO1999016476A1 (en) * 1997-10-01 1999-04-08 Perex Agorreta Francisco Javie Device for reproducing or synthetising odors or aromas
WO1999038102A1 (en) * 1998-01-23 1999-07-29 Bala Narayanaswamy Olfactory emitting system

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
GOPEL W: "Chemical imaging: I. Concepts and visions for electronic and bioelectronic noses", SENSORS AND ACTUATORS B,CH,ELSEVIER SEQUOIA S.A., LAUSANNE, vol. 52, no. 1-2, 15 September 1998 (1998-09-15), pages 125 - 142, XP004157827, ISSN: 0925-4005 *
PATENT ABSTRACTS OF JAPAN vol. 1995, no. 06 31 July 1995 (1995-07-31) *
TZONG-ZENG WU: "A piezoelectric biosensor as an olfactory receptor for odour detection: electronic nose", BIOSENSORS & BIOELECTRONICS, 1 JAN. 1999, ELSEVIER, UK, vol. 14, no. 1, pages 9 - 18, XP000938636, ISSN: 0956-5663 *

Also Published As

Publication number Publication date
WO2000070343A2 (en) 2000-11-23
AU4847600A (en) 2000-12-05

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