WO2000070340A3 - Materials and methods relating to disease diagnosis - Google Patents

Materials and methods relating to disease diagnosis Download PDF

Info

Publication number
WO2000070340A3
WO2000070340A3 PCT/EP2000/004265 EP0004265W WO0070340A3 WO 2000070340 A3 WO2000070340 A3 WO 2000070340A3 EP 0004265 W EP0004265 W EP 0004265W WO 0070340 A3 WO0070340 A3 WO 0070340A3
Authority
WO
WIPO (PCT)
Prior art keywords
materials
methods relating
disease diagnosis
provides
diagnosis
Prior art date
Application number
PCT/EP2000/004265
Other languages
French (fr)
Other versions
WO2000070340A2 (en
Inventor
Bo Franzen
Anders Hagman
Alaiya Ayodele
Original Assignee
Karolinska Innovations Ab
Bo Franzen
Anders Hagman
Alaiya Ayodele
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Karolinska Innovations Ab, Bo Franzen, Anders Hagman, Alaiya Ayodele filed Critical Karolinska Innovations Ab
Priority to EP00931192A priority Critical patent/EP1179175A2/en
Priority to AU49208/00A priority patent/AU773329B2/en
Publication of WO2000070340A2 publication Critical patent/WO2000070340A2/en
Publication of WO2000070340A3 publication Critical patent/WO2000070340A3/en

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2550/00—Electrophoretic profiling, e.g. for proteome analysis

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Hematology (AREA)
  • Chemical & Material Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Biomedical Technology (AREA)
  • Biophysics (AREA)
  • Food Science & Technology (AREA)
  • Biotechnology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Microbiology (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cell Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)

Abstract

The invention provides materials and methods relating to disease diagnosis. In particular, the invention provides a method of diagnosing diseases, such as cancers, by comparing specific patterns of gene expression characteristic of the disease at a nucleic acid or protein level. The invention provides novel methods for analysing the expression profiles characteristic of diseased cells, in order to determine specific diagnostic markers. Such determined diagnostic markers may be stored on, for example a database, and used in the diagnosis of diseases such as cancer.
PCT/EP2000/004265 1999-05-14 2000-05-11 Materials and methods relating to disease diagnosis WO2000070340A2 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
EP00931192A EP1179175A2 (en) 1999-05-14 2000-05-11 Materials and methods relating to disease diagnosis
AU49208/00A AU773329B2 (en) 1999-05-14 2000-05-11 Materials and methods relating to disease diagnosis

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US13435699P 1999-05-14 1999-05-14
US60/134,356 1999-05-14

Publications (2)

Publication Number Publication Date
WO2000070340A2 WO2000070340A2 (en) 2000-11-23
WO2000070340A3 true WO2000070340A3 (en) 2001-02-08

Family

ID=22462994

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP2000/004265 WO2000070340A2 (en) 1999-05-14 2000-05-11 Materials and methods relating to disease diagnosis

Country Status (3)

Country Link
EP (1) EP1179175A2 (en)
AU (1) AU773329B2 (en)
WO (1) WO2000070340A2 (en)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MXPA01010970A (en) * 1999-04-26 2003-03-27 Surromed Inc Phenotype and biological marker identification system.
US7567870B1 (en) 2000-07-31 2009-07-28 Institute For Systems Biology Multiparameter analysis for predictive medicine
WO2002010456A2 (en) * 2000-07-31 2002-02-07 The Institute For Systems Biology Multiparameter analysis for predictive medicine
US7343247B2 (en) 2001-07-30 2008-03-11 The Institute For Systems Biology Methods of classifying drug responsiveness using multiparameter analysis
EP1319954A1 (en) * 2001-12-12 2003-06-18 Centre National de Genotypage Methods for protein analysis using protein capture arrays
JPWO2003085548A1 (en) * 2002-04-04 2005-08-11 石原産業株式会社 Data analysis apparatus and method
AT414171B (en) * 2002-12-19 2006-09-15 Red Bull Gmbh Down syndrome diagnosis involves providing amniotic fluid sample, blood or serum sample of pregnant women or brain tissue sample
US7464835B2 (en) 2002-12-19 2008-12-16 Braun Gmbh Preparing and dispensing mixed beverages
AU2003901196A0 (en) * 2003-03-17 2003-04-03 Commonwealth Scientific And Industrial Research Organisation Analysis method
DE602004024539D1 (en) * 2003-07-03 2010-01-21 Gentron Llc METHOD AND SYSTEMS FOR DIAGNOSIS OF NON-DISTRACTIVE CNS DISEASES IN CNS SAMPLES
AT500564B1 (en) * 2003-12-30 2006-02-15 Red Bull Gmbh Diagnosis of embryonal tumors, particularly primitive neuroectodermal tumors, by detecting expression, in a cerebral sample, of specific marker proteins
AT413542B (en) * 2003-12-30 2006-03-15 Red Bull Gmbh In vitro diagnosis of inherited metabolic anomalies, including those associated with multiple enzyme defects, comprises analysis of many proteins extracted from patient lymphocytes
WO2006079034A2 (en) * 2005-01-21 2006-07-27 Gene Express, Inc. Business methods for assessing nucleic acids
US10762982B1 (en) * 2015-10-07 2020-09-01 Trace Genomics, Inc. System and method for nucleotide analysis

Citations (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5426029A (en) * 1986-03-31 1995-06-20 T Cell Diagnostics, Inc. Therapeutic and diagnostic methods using leukocyte surface antigens
US5492547A (en) * 1993-09-14 1996-02-20 Dekalb Genetics Corp. Process for predicting the phenotypic trait of yield in maize
US5583201A (en) * 1990-11-30 1996-12-10 Monoclonetics International, Inc. Methods for diagnosis of peripheral nerve damage
US5635365A (en) * 1995-08-07 1997-06-03 Emory University Noninvasive diagnosis for allograft rejection
WO1997022720A1 (en) * 1995-12-21 1997-06-26 Kenneth Loren Beattie Arbitrary sequence oligonucleotide fingerprinting
WO1997041441A1 (en) * 1996-04-26 1997-11-06 Children's Medical Center Corporation Non-invasive enzyme screen for tissue remodelling-associated conditions
WO1998027226A2 (en) * 1996-12-16 1998-06-25 Nova Molecular, Inc. Method for determining the prognosis of a patient with a neurological disease
WO1998053319A2 (en) * 1997-05-21 1998-11-26 The Johns Hopkins University Gene expression profiles in normal and cancer cells
WO1999029877A1 (en) * 1997-12-12 1999-06-17 The Regents Of The University Of California Methods for defining cell types
WO1999044062A1 (en) * 1998-02-25 1999-09-02 The United States Of America As Represented By The Secretary Department Of Health And Human Services Cellular arrays for rapid molecular profiling
WO2000011208A1 (en) * 1998-08-25 2000-03-02 University Of Washington Rapid quantitative analysis of proteins or protein function in complex mixtures
WO2000029444A1 (en) * 1998-11-16 2000-05-25 Genway Biotech, Inc. Generation of antibodies using polynucleotide vaccination in avian species
WO2000042838A2 (en) * 1999-01-21 2000-07-27 Pioneer Hi-Bred International, Inc. Molecular profiling for heterosis selection

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1998020124A2 (en) * 1996-10-25 1998-05-14 Peter Mose Larsen Diabetes-mediating proteins and therapeutic uses thereof

Patent Citations (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5426029A (en) * 1986-03-31 1995-06-20 T Cell Diagnostics, Inc. Therapeutic and diagnostic methods using leukocyte surface antigens
US5583201A (en) * 1990-11-30 1996-12-10 Monoclonetics International, Inc. Methods for diagnosis of peripheral nerve damage
US5492547B1 (en) * 1993-09-14 1998-06-30 Dekalb Genetics Corp Process for predicting the phenotypic trait of yield in maize
US5492547A (en) * 1993-09-14 1996-02-20 Dekalb Genetics Corp. Process for predicting the phenotypic trait of yield in maize
US5635365A (en) * 1995-08-07 1997-06-03 Emory University Noninvasive diagnosis for allograft rejection
WO1997022720A1 (en) * 1995-12-21 1997-06-26 Kenneth Loren Beattie Arbitrary sequence oligonucleotide fingerprinting
WO1997041441A1 (en) * 1996-04-26 1997-11-06 Children's Medical Center Corporation Non-invasive enzyme screen for tissue remodelling-associated conditions
WO1998027226A2 (en) * 1996-12-16 1998-06-25 Nova Molecular, Inc. Method for determining the prognosis of a patient with a neurological disease
WO1998053319A2 (en) * 1997-05-21 1998-11-26 The Johns Hopkins University Gene expression profiles in normal and cancer cells
WO1999029877A1 (en) * 1997-12-12 1999-06-17 The Regents Of The University Of California Methods for defining cell types
WO1999044062A1 (en) * 1998-02-25 1999-09-02 The United States Of America As Represented By The Secretary Department Of Health And Human Services Cellular arrays for rapid molecular profiling
WO2000011208A1 (en) * 1998-08-25 2000-03-02 University Of Washington Rapid quantitative analysis of proteins or protein function in complex mixtures
WO2000029444A1 (en) * 1998-11-16 2000-05-25 Genway Biotech, Inc. Generation of antibodies using polynucleotide vaccination in avian species
WO2000042838A2 (en) * 1999-01-21 2000-07-27 Pioneer Hi-Bred International, Inc. Molecular profiling for heterosis selection

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
See also references of EP1179175A2 *

Also Published As

Publication number Publication date
WO2000070340A2 (en) 2000-11-23
AU773329B2 (en) 2004-05-20
EP1179175A2 (en) 2002-02-13
AU4920800A (en) 2000-12-05

Similar Documents

Publication Publication Date Title
WO2007016367A3 (en) Neoplastic disease-related methods, kits, systems and databases
WO2000070340A3 (en) Materials and methods relating to disease diagnosis
NO972006D0 (en) New method for diagnosis of diseases
WO2005000098A3 (en) Detection methods for disorders of the lung
WO2001018252A3 (en) Methods for disease detection
WO2002024956A8 (en) Genetic markers for tumors
WO2003100557A3 (en) Computer systems and methods for subdividing a complex disease into component diseases
AU2002327308A1 (en) Methods for evaluating pathologic conditions using extracellular rna
EP1521083A3 (en) Method for diagnosing and distinguishing stroke
WO2004112589A3 (en) Method for the detection of gene transcripts in blood and uses thereof
WO2000066780A3 (en) Adeno-associated virus-delivered ribozyme compositions and methods of use
WO2001042502A3 (en) Methods for disease detection
WO2002046465A3 (en) Method for identification of genes involved in specific diseases
WO2004000094A8 (en) Predictive markers in cancer therapy
WO1998009990A8 (en) Fungal antigens and process for producing the same
WO2002074911A3 (en) Identification of gene expression alterations underlying the aging process in mammals
WO2007020522A3 (en) Protein markers for diagnosing of colorectal cancer and use of said markers as drug targets for the treatment of said cancer type
CA2366514A1 (en) Diagnostic and therapeutic use of antibodies against the urokinase receptor
WO2004113574A3 (en) Methods for disease screening
ATE352039T1 (en) METHOD FOR DETERMINING THYMIDINKINASE-1 ACTIVITY AND USE THEREOF
RS20060255A (en) Quick test for the diagnosis of alzheimer's disease
WO2001049879A3 (en) Methods for comparing gene expression levels or patterns in normal or tumor cells
WO2006042005A3 (en) Global gene expression profiling of circulating tumor cells
WO2003043580A3 (en) Methods for identifying and validating potential drug targets
WO2004021119A3 (en) Methods for recruiting patients for clinical studies

Legal Events

Date Code Title Description
AK Designated states

Kind code of ref document: A2

Designated state(s): AE AG AL AM AT AU AZ BA BB BG BR BY CA CH CN CR CU CZ DE DK DM DZ EE ES FI GB GD GE GH GM HR HU ID IL IN IS JP KE KG KP KR KZ LC LK LR LS LT LU LV MA MD MG MK MN MW MX NO NZ PL PT RO RU SD SE SG SI SK SL TJ TM TR TT TZ UA UG US UZ VN YU ZA ZW

AL Designated countries for regional patents

Kind code of ref document: A2

Designated state(s): GH GM KE LS MW SD SL SZ TZ UG ZW AM AZ BY KG KZ MD RU TJ TM AT BE CH CY DE DK ES FI FR GB GR IE IT LU MC NL PT SE BF BJ CF CG CI CM GA GN GW ML MR NE SN TD TG

121 Ep: the epo has been informed by wipo that ep was designated in this application
AK Designated states

Kind code of ref document: A3

Designated state(s): AE AG AL AM AT AU AZ BA BB BG BR BY CA CH CN CR CU CZ DE DK DM DZ EE ES FI GB GD GE GH GM HR HU ID IL IN IS JP KE KG KP KR KZ LC LK LR LS LT LU LV MA MD MG MK MN MW MX NO NZ PL PT RO RU SD SE SG SI SK SL TJ TM TR TT TZ UA UG US UZ VN YU ZA ZW

AL Designated countries for regional patents

Kind code of ref document: A3

Designated state(s): GH GM KE LS MW SD SL SZ TZ UG ZW AM AZ BY KG KZ MD RU TJ TM AT BE CH CY DE DK ES FI FR GB GR IE IT LU MC NL PT SE BF BJ CF CG CI CM GA GN GW ML MR NE SN TD TG

DFPE Request for preliminary examination filed prior to expiration of 19th month from priority date (pct application filed before 20040101)
WWE Wipo information: entry into national phase

Ref document number: 2000931192

Country of ref document: EP

WWE Wipo information: entry into national phase

Ref document number: 49208/00

Country of ref document: AU

WWP Wipo information: published in national office

Ref document number: 2000931192

Country of ref document: EP

REG Reference to national code

Ref country code: DE

Ref legal event code: 8642

WWE Wipo information: entry into national phase

Ref document number: 09979461

Country of ref document: US

NENP Non-entry into the national phase

Ref country code: JP

WWG Wipo information: grant in national office

Ref document number: 49208/00

Country of ref document: AU

WWW Wipo information: withdrawn in national office

Ref document number: 2000931192

Country of ref document: EP