WO2000067022A3 - Labormässige untersuchung einer körperflüssigkeits- oder gewebeprobe - Google Patents

Labormässige untersuchung einer körperflüssigkeits- oder gewebeprobe Download PDF

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Publication number
WO2000067022A3
WO2000067022A3 PCT/EP2000/004003 EP0004003W WO0067022A3 WO 2000067022 A3 WO2000067022 A3 WO 2000067022A3 EP 0004003 W EP0004003 W EP 0004003W WO 0067022 A3 WO0067022 A3 WO 0067022A3
Authority
WO
WIPO (PCT)
Prior art keywords
body fluid
tissue sample
laboratory examination
hydroxyproline
cis
Prior art date
Application number
PCT/EP2000/004003
Other languages
English (en)
French (fr)
Other versions
WO2000067022A2 (de
Inventor
Wilhelm Hoerrmann
Original Assignee
Wilhelm Hoerrmann
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wilhelm Hoerrmann filed Critical Wilhelm Hoerrmann
Priority to DE50006083T priority Critical patent/DE50006083C5/de
Priority to AT00929493T priority patent/ATE264505T1/de
Priority to JP2000615810A priority patent/JP2002543427A/ja
Priority to EP00929493A priority patent/EP1188055B1/de
Priority to CA002370427A priority patent/CA2370427A1/en
Publication of WO2000067022A2 publication Critical patent/WO2000067022A2/de
Publication of WO2000067022A3 publication Critical patent/WO2000067022A3/de

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Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins
    • G01N33/6806—Determination of free amino acids
    • G01N33/6812—Assays for specific amino acids

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  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Hematology (AREA)
  • Chemical & Material Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Biomedical Technology (AREA)
  • Biophysics (AREA)
  • Food Science & Technology (AREA)
  • Biotechnology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Microbiology (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cell Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Sampling And Sample Adjustment (AREA)

Abstract

Bei einer labormässigen Untersuchung einer Körperflüssigkeits- oder Gewebeprobe erfolgt ein quantitativ analytischer Nachweis von cis-Hydroxyprolin und Derivaten hiervon. Ein für die Bestimmung des Gehalts der Probe an cis-Hydroxyprolin und Derivaten hiervon unter Anwendung der HPLC-Methode geeigneter Analysekit umfasst HCl (10 M), NaOH (16 M), Na2CO3 (4 M), Ortho-Phthaldialdehyd, wässrigen Phosphat-Puffer und Dabsylchlorid.
PCT/EP2000/004003 1999-05-04 2000-05-04 Labormässige untersuchung einer körperflüssigkeits- oder gewebeprobe WO2000067022A2 (de)

Priority Applications (5)

Application Number Priority Date Filing Date Title
DE50006083T DE50006083C5 (de) 1999-05-04 2000-05-04 Labormässige untersuchung einer körperflüssigkeits- oder gewebeprobe
AT00929493T ATE264505T1 (de) 1999-05-04 2000-05-04 Labormässige untersuchung einer körperflüssigkeits- oder gewebeprobe
JP2000615810A JP2002543427A (ja) 1999-05-04 2000-05-04 体液または組織プローブの実験室検査
EP00929493A EP1188055B1 (de) 1999-05-04 2000-05-04 Labormässige untersuchung einer körperflüssigkeits- oder gewebeprobe
CA002370427A CA2370427A1 (en) 1999-05-04 2000-05-04 Laboratory examination of a body fluid or tissue sample

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19920434 1999-05-04
DE19920434.9 1999-05-04

Publications (2)

Publication Number Publication Date
WO2000067022A2 WO2000067022A2 (de) 2000-11-09
WO2000067022A3 true WO2000067022A3 (de) 2001-04-26

Family

ID=7906897

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP2000/004003 WO2000067022A2 (de) 1999-05-04 2000-05-04 Labormässige untersuchung einer körperflüssigkeits- oder gewebeprobe

Country Status (6)

Country Link
EP (1) EP1188055B1 (de)
JP (1) JP2002543427A (de)
AT (1) ATE264505T1 (de)
CA (1) CA2370427A1 (de)
DE (1) DE50006083C5 (de)
WO (1) WO2000067022A2 (de)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102590420A (zh) * 2012-02-15 2012-07-18 上海德诺产品检测有限公司 一种乳制品中l-羟脯氨酸含量的检测方法
WO2015033636A1 (ja) * 2013-09-09 2015-03-12 国立大学法人愛媛大学 ３－ヒドロキシプロリンの分析方法、コラーゲンの測定方法、およびそれに用いる新規δ１－ピロリン－２－カルボン酸還元酵素
CN104697835B (zh) * 2015-03-24 2017-06-16 李乐 纺织品中芳香胺检测用标准混标溶液及其制备方法与用途

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1997033578A1 (de) * 1996-03-11 1997-09-18 Wilhelm Hoerrmann Kombination aus cis-4-hydroxy-l-prolin und n-methyl-cis-4-hydroxy-l-prolin zur anwendung als therapeutischer wirkstoff insbesondere für die krebstherapie

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1997033578A1 (de) * 1996-03-11 1997-09-18 Wilhelm Hoerrmann Kombination aus cis-4-hydroxy-l-prolin und n-methyl-cis-4-hydroxy-l-prolin zur anwendung als therapeutischer wirkstoff insbesondere für die krebstherapie

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
APPLIED AND ENVIRONMENTAL MICROBIOLOGY, vol. 62, no. 6, 1996, pages 1903 - 1907, ISSN: 0099-2240 *
ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS, vol. 229, no. 2, 1984, pages 455 - 458, ISSN: 0003-9861 *
DATABASE BIOSIS [online] BIOSCIENCES INFORMATION SERVICE, PHILADELPHIA, PA, US; 1984, BIENKOWSKI R S: "A CRITERION TO DETERMINE WHETHER CIS-4 HYDROXY PROLINE IS PRODUCED IN ANIMAL TISSUES", XP002154374, Database accession no. PREV198478044739 *
DATABASE BIOSIS [online] BIOSCIENCES INFORMATION SERVICE, PHILADELPHIA, PA, US; 1996, MORI HIDEO ET AL: "Detection of novel proline 3-hydroxylase activities in Streptomyces and Bacillus spp. by regio- and stereospecific hydroxylation of L-proline.", XP002154373, Database accession no. PREV199699037561 *

Also Published As

Publication number Publication date
JP2002543427A (ja) 2002-12-17
DE50006083D1 (de) 2004-05-19
EP1188055A2 (de) 2002-03-20
DE50006083C5 (de) 2006-01-26
EP1188055B1 (de) 2004-04-14
WO2000067022A2 (de) 2000-11-09
CA2370427A1 (en) 2000-11-09
ATE264505T1 (de) 2004-04-15

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