WO2000065026A3 - YycG - Google Patents

YycG Download PDF

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Publication number
WO2000065026A3
WO2000065026A3 PCT/US2000/010991 US0010991W WO0065026A3 WO 2000065026 A3 WO2000065026 A3 WO 2000065026A3 US 0010991 W US0010991 W US 0010991W WO 0065026 A3 WO0065026 A3 WO 0065026A3
Authority
WO
WIPO (PCT)
Prior art keywords
yycg
polypeptides
methods
polynucletodes
encoding
Prior art date
Application number
PCT/US2000/010991
Other languages
French (fr)
Other versions
WO2000065026A2 (en
Inventor
John P Throup
Horn Stephanie Van
Richard L Warren
Sanjoy Biswas
David J Holmes
Alison F Chalker
Karen A Ingraham
Chi Young So
Magdalena Zalacain
Alexander Bryant
Martin K R Burnham
Original Assignee
Smithkline Beecham Corp
Smithkline Beecham Plc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smithkline Beecham Corp, Smithkline Beecham Plc filed Critical Smithkline Beecham Corp
Publication of WO2000065026A2 publication Critical patent/WO2000065026A2/en
Publication of WO2000065026A3 publication Critical patent/WO2000065026A3/en

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/12—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
    • C12N9/1223—Phosphotransferases with a nitrogenous group as acceptor (2.7.3)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/315—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Streptococcus (G), e.g. Enterococci
    • C07K14/3156—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Streptococcus (G), e.g. Enterococci from Streptococcus pneumoniae (Pneumococcus)

Abstract

The invention provides YycG polypeptides and polynucletodes encoding YycG polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing YycG polypeptides to screen for antibacterial compounds.
PCT/US2000/010991 1999-04-28 2000-04-24 YycG WO2000065026A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US30048999A 1999-04-28 1999-04-28
US09/300,489 1999-04-28

Publications (2)

Publication Number Publication Date
WO2000065026A2 WO2000065026A2 (en) 2000-11-02
WO2000065026A3 true WO2000065026A3 (en) 2001-02-08

Family

ID=23159312

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2000/010991 WO2000065026A2 (en) 1999-04-28 2000-04-24 YycG

Country Status (1)

Country Link
WO (1) WO2000065026A2 (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1572868A4 (en) 2001-04-16 2007-04-04 Wyeth Corp Novel streptococcus pneumoniae open reading frames encoding polypeptide antigens and uses thereof
CN106188302A (en) * 2015-05-08 2016-12-07 复旦大学 YycG-PAS monoclonal antibody and application thereof

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1998018931A2 (en) * 1996-10-31 1998-05-07 Human Genome Sciences, Inc. Streptococcus pneumoniae polynucleotides and sequences
EP0885965A2 (en) * 1997-06-20 1998-12-23 Smithkline Beecham Corporation Histidine kinase polypeptides
EP0892059A2 (en) * 1997-06-20 1999-01-20 Smithkline Beecham Corporation Histidine kinase polypeptides

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1998018931A2 (en) * 1996-10-31 1998-05-07 Human Genome Sciences, Inc. Streptococcus pneumoniae polynucleotides and sequences
EP0885965A2 (en) * 1997-06-20 1998-12-23 Smithkline Beecham Corporation Histidine kinase polypeptides
EP0892059A2 (en) * 1997-06-20 1999-01-20 Smithkline Beecham Corporation Histidine kinase polypeptides

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
DATABASE GENESEQ ON STN BARASH ET AL., XP002933871 *
GUENZI ET AL.: "A two-component signal-transducing system is involved incompetence and penicillin susceptibility in laboratory mutants of streptococcus pneumoniae", MOL. MICROBIOL., vol. 12, no. 3, 1 March 1994 (1994-03-01), pages 505 - 515, XP002933870 *
PESTOVA ET AL.: "Regulation of competence for genetic transformation in streptococcus pneumoniae by an auto-induced peptide pheromone and a two-component regulatory system", MOL. MICROBIOL., vol. 21, no. 4, 1 July 1996 (1996-07-01), pages 853 - 862, XP002933869 *

Also Published As

Publication number Publication date
WO2000065026A2 (en) 2000-11-02

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