WO2000063385A3 - Immunisation de l'acide nucleique - Google Patents

Immunisation de l'acide nucleique Download PDF

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Publication number
WO2000063385A3
WO2000063385A3 PCT/US2000/010766 US0010766W WO0063385A3 WO 2000063385 A3 WO2000063385 A3 WO 2000063385A3 US 0010766 W US0010766 W US 0010766W WO 0063385 A3 WO0063385 A3 WO 0063385A3
Authority
WO
WIPO (PCT)
Prior art keywords
nucleic acid
reagents
acid immunization
molecules
methods
Prior art date
Application number
PCT/US2000/010766
Other languages
English (en)
Other versions
WO2000063385A2 (fr
Inventor
Dexiang Chen
James T Fuller
Original Assignee
Powderject Vaccines Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Powderject Vaccines Inc filed Critical Powderject Vaccines Inc
Priority to JP2000612464A priority Critical patent/JP2002542264A/ja
Priority to NZ515041A priority patent/NZ515041A/xx
Priority to AU44797/00A priority patent/AU4479700A/en
Priority to CA002370646A priority patent/CA2370646A1/fr
Priority to EP00926234A priority patent/EP1180150A2/fr
Publication of WO2000063385A2 publication Critical patent/WO2000063385A2/fr
Publication of WO2000063385A3 publication Critical patent/WO2000063385A3/fr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/102—Pasteurellales, e.g. Actinobacillus, Pasteurella; Haemophilus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/09—Lactobacillales, e.g. aerococcus, enterococcus, lactobacillus, lactococcus, streptococcus
    • A61K39/092—Streptococcus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/095—Neisseria
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/385—Haptens or antigens, bound to carriers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/53—DNA (RNA) vaccination
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/60—Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
    • A61K2039/6031—Proteins
    • A61K2039/6075—Viral proteins

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Microbiology (AREA)
  • Immunology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Communicable Diseases (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)

Abstract

L'invention porte sur des molécules d'acide nucléique de recombinaison. Les molécules possèdent une première séquence codant un peptide qui stimule un antigène cible. L'invention porte également sur des réactifs tels que des vecteurs et sur des compositions contenant ces molécules; sur des procédés de construction de ces réactifs et sur des procédés d'utilisation de ces réactifs pour déclencher une réponse immunitaire.
PCT/US2000/010766 1999-04-21 2000-04-21 Immunisation de l'acide nucleique WO2000063385A2 (fr)

Priority Applications (5)

Application Number Priority Date Filing Date Title
JP2000612464A JP2002542264A (ja) 1999-04-21 2000-04-21 核酸による免疫化
NZ515041A NZ515041A (en) 1999-04-21 2000-04-21 Nucleic acid immunization
AU44797/00A AU4479700A (en) 1999-04-21 2000-04-21 Nucleic acid immunization
CA002370646A CA2370646A1 (fr) 1999-04-21 2000-04-21 Immunisation de l'acide nucleique
EP00926234A EP1180150A2 (fr) 1999-04-21 2000-04-21 Immunisation de l'acide nucleique

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US13024999P 1999-04-21 1999-04-21
US60/130,249 1999-04-21

Publications (2)

Publication Number Publication Date
WO2000063385A2 WO2000063385A2 (fr) 2000-10-26
WO2000063385A3 true WO2000063385A3 (fr) 2001-02-22

Family

ID=22443785

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2000/010766 WO2000063385A2 (fr) 1999-04-21 2000-04-21 Immunisation de l'acide nucleique

Country Status (6)

Country Link
EP (1) EP1180150A2 (fr)
JP (1) JP2002542264A (fr)
AU (1) AU4479700A (fr)
CA (1) CA2370646A1 (fr)
NZ (1) NZ515041A (fr)
WO (1) WO2000063385A2 (fr)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9107906B1 (en) 2014-10-28 2015-08-18 Adma Biologics, Inc. Compositions and methods for the treatment of immunodeficiency

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2004535358A (ja) * 2000-11-02 2004-11-25 パウダージェクト ワクチンズ，インコーポレーテッド 核酸免疫
CN1842349A (zh) * 2003-08-29 2006-10-04 安琪士摩奇株式会社 使用无针注射器进行皮肤疾病基因治疗
WO2006027244A2 (fr) * 2004-09-10 2006-03-16 Bracco Imaging S.P.A. Complexes metalliques paramagnetiques pour la visualisation en irm de polynucleotides internalises
WO2006133497A1 (fr) * 2005-06-15 2006-12-21 Adelaide Research & Innovation Pty Ltd Traitement combiné
WO2007087758A2 (fr) * 2006-01-31 2007-08-09 Centro De Ingenieria Genetica Y Biotecnologia Mimotopes de polysaccharides capsulaires de neisseria meningitidis et leurs formulations pharmaceutiques
EP3590503A1 (fr) 2006-10-12 2020-01-08 The University of Queensland Compositions et procédés pour moduler les réponses immunologiques
BR112013010926A2 (pt) 2010-11-01 2016-08-23 Univ Technology Sidney agentes imunomoduladores e seus usos
US10259865B2 (en) 2017-03-15 2019-04-16 Adma Biologics, Inc. Anti-pneumococcal hyperimmune globulin for the treatment and prevention of pneumococcal infection
MX2020007246A (es) 2017-10-13 2020-11-13 Univ New York State Res Found Diseño de vacuna integral para el avance de enfermedad comensal.

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1994027435A1 (fr) * 1993-06-01 1994-12-08 Life Technologies, Inc. Immunisation genetique a l'aide de lipides cationiques
WO1997011605A1 (fr) * 1995-09-28 1997-04-03 University Of Pittsburgh Of The Commonwealth System Of Higher Education Stimulation de reponses immunes cellulaires par une imunisation genique ciblee utilisant un agent particulaire
WO1998022145A1 (fr) * 1996-11-22 1998-05-28 Mount Sinai School Of Medicine Of The City University Of New York Immunisation de nourrissons
US5766878A (en) * 1996-05-01 1998-06-16 Smithkline Beecham Corporation Polynucleotides encoding a transcriptional response regulator of streptococcus pneumoniae
US5865796A (en) * 1994-01-21 1999-02-02 Powderject Vaccines, Inc Gas driven gene delivery instrument

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1994027435A1 (fr) * 1993-06-01 1994-12-08 Life Technologies, Inc. Immunisation genetique a l'aide de lipides cationiques
US5865796A (en) * 1994-01-21 1999-02-02 Powderject Vaccines, Inc Gas driven gene delivery instrument
WO1997011605A1 (fr) * 1995-09-28 1997-04-03 University Of Pittsburgh Of The Commonwealth System Of Higher Education Stimulation de reponses immunes cellulaires par une imunisation genique ciblee utilisant un agent particulaire
US5766878A (en) * 1996-05-01 1998-06-16 Smithkline Beecham Corporation Polynucleotides encoding a transcriptional response regulator of streptococcus pneumoniae
WO1998022145A1 (fr) * 1996-11-22 1998-05-28 Mount Sinai School Of Medicine Of The City University Of New York Immunisation de nourrissons

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
MILICH D R ET AL: "THE HEPATITIS NUCLEOCAPSID AS A VACCINE CARRIER MOIETY", ANNALS OF THE NEW YORK ACADEMY OF SCIENCES,NEW YORK ACADEMY OF SCIENCES, NEW YORK, NY,US, vol. 754, 31 May 1995 (1995-05-31), pages 187 - 201, XP000891480, ISSN: 0077-8923 *
SCHOEDEL F ET AL: "IMMUNITY TO MALARIA ELICITED BY HYBRID HEPATITIS B VIRUS CORE PARTICLES CARRYING CIRCUMSPOROZOITE PROTEIN EPITOPES", JOURNAL OF EXPERIMENTAL MEDICINE,TOKYO,JP, vol. 180, no. 3, September 1994 (1994-09-01), pages 1037 - 1046, XP000891465, ISSN: 0022-1007 *
WESTERINK ET AL.: "Peptide mimicry of the meningococcal group C capsular polysaccharide", PROC NATL ACAD SCI USA, vol. 92, April 1995 (1995-04-01), pages 4021 - 4025, XP002150633 *

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9107906B1 (en) 2014-10-28 2015-08-18 Adma Biologics, Inc. Compositions and methods for the treatment of immunodeficiency

Also Published As

Publication number Publication date
NZ515041A (en) 2004-03-26
WO2000063385A2 (fr) 2000-10-26
AU4479700A (en) 2000-11-02
CA2370646A1 (fr) 2000-10-26
JP2002542264A (ja) 2002-12-10
EP1180150A2 (fr) 2002-02-20

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