WO2000060080A3 - Molecules du systeme immunitaire - Google Patents

Molecules du systeme immunitaire Download PDF

Info

Publication number
WO2000060080A3
WO2000060080A3 PCT/US2000/009072 US0009072W WO0060080A3 WO 2000060080 A3 WO2000060080 A3 WO 2000060080A3 US 0009072 W US0009072 W US 0009072W WO 0060080 A3 WO0060080 A3 WO 0060080A3
Authority
WO
WIPO (PCT)
Prior art keywords
imol
immune system
molecules
provides
expression
Prior art date
Application number
PCT/US2000/009072
Other languages
English (en)
Other versions
WO2000060080A2 (fr
Inventor
Henry Yue
Preeti Lal
Y Tom Tang
Mariah R Baughn
Yalda Azimzai
Dyung Aina M Lu
Original Assignee
Incyte Pharma Inc
Henry Yue
Preeti Lal
Y Tom Tang
Mariah R Baughn
Yalda Azimzai
Dyung Aina M Lu
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Incyte Pharma Inc, Henry Yue, Preeti Lal, Y Tom Tang, Mariah R Baughn, Yalda Azimzai, Dyung Aina M Lu filed Critical Incyte Pharma Inc
Priority to EP00921733A priority Critical patent/EP1165788A2/fr
Priority to JP2000609571A priority patent/JP2002540791A/ja
Priority to CA002367378A priority patent/CA2367378A1/fr
Priority to AU42010/00A priority patent/AU4201000A/en
Publication of WO2000060080A2 publication Critical patent/WO2000060080A2/fr
Publication of WO2000060080A3 publication Critical patent/WO2000060080A3/fr

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705Receptors; Cell surface antigens; Cell surface determinants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/12Drugs for disorders of the urinary system of the kidneys
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/06Antipsoriatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/02Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00Drugs for disorders of the muscular or neuromuscular system
    • A61P21/04Drugs for disorders of the muscular or neuromuscular system for myasthenia gravis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10Antimycotics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00Antiparasitic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00Antiparasitic agents
    • A61P33/02Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • A61P33/08Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis for Pneumocystis carinii
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00Antiparasitic agents
    • A61P33/10Anthelmintics
    • A61P33/12Schistosomicides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/02Antineoplastic agents specific for leukemia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/08Antiallergic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/08Plasma substitutes; Perfusion solutions; Dialytics or haemodialytics; Drugs for electrolytic or acid-base disorders, e.g. hypovolemic shock
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01KANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2217/00Genetically modified animals
    • A01K2217/05Animals comprising random inserted nucleic acids (transgenic)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Oncology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Genetics & Genomics (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • Pulmonology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Zoology (AREA)
  • Rheumatology (AREA)
  • Communicable Diseases (AREA)
  • Dermatology (AREA)
  • Toxicology (AREA)
  • Endocrinology (AREA)
  • Vascular Medicine (AREA)
  • Cell Biology (AREA)
  • Cardiology (AREA)
  • Obesity (AREA)

Abstract

L'invention concerne des molécules du système immunitaire humain (IMOL) ainsi que des polynucléotides identifiant et codant pour ces molécules IMOL. Cette invention concerne également des vecteurs d'expression, des cellules hôtes, des anticorps, des agonistes, et des antagonistes. Cette invention concerne enfin des méthodes permettant de diagnostiquer, de traiter ou de prévenir les troubles liés à l'expression desdites molécules IMOL.
PCT/US2000/009072 1999-04-05 2000-04-04 Molecules du systeme immunitaire WO2000060080A2 (fr)

Priority Applications (4)

Application Number Priority Date Filing Date Title
EP00921733A EP1165788A2 (fr) 1999-04-05 2000-04-04 Molecules du systeme immunitaire
JP2000609571A JP2002540791A (ja) 1999-04-05 2000-04-04 免疫系の分子
CA002367378A CA2367378A1 (fr) 1999-04-05 2000-04-04 Molecules du systeme immunitaire
AU42010/00A AU4201000A (en) 1999-04-05 2000-04-04 Molecules of the immune system

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US12785299P 1999-04-05 1999-04-05
US13264799P 1999-05-05 1999-05-05
US60/132,647 1999-05-05
US60/127,852 1999-05-05

Publications (2)

Publication Number Publication Date
WO2000060080A2 WO2000060080A2 (fr) 2000-10-12
WO2000060080A3 true WO2000060080A3 (fr) 2001-01-25

Family

ID=26826031

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2000/009072 WO2000060080A2 (fr) 1999-04-05 2000-04-04 Molecules du systeme immunitaire

Country Status (5)

Country Link
EP (1) EP1165788A2 (fr)
JP (1) JP2002540791A (fr)
AU (1) AU4201000A (fr)
CA (1) CA2367378A1 (fr)
WO (1) WO2000060080A2 (fr)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1006184A1 (fr) 1998-12-03 2000-06-07 F. Hoffmann-La Roche Ag Protéines interagissant avec le récepteur de IGF-1, gènes codant pour ces protéines et leurs utilisations
US6521233B1 (en) 1999-04-20 2003-02-18 Zymogenetics, Inc. Adipocyte complement related protein homolog zacrp3
EP1218408A4 (fr) * 1999-09-24 2003-02-26 Human Genome Sciences Inc 32 proteines humaines secretees
US20020081625A1 (en) * 1999-10-14 2002-06-27 John Ford Member of the immunoglobulin superfamily and uses thereof
US7094566B2 (en) 2000-03-16 2006-08-22 Amgen Inc., IL-17 receptor like molecules and uses thereof
AR030554A1 (es) * 2000-03-16 2003-08-27 Amgen Inc Moleculas similares a receptores il-17 y usos de las mismas
WO2001088137A2 (fr) 2000-05-17 2001-11-22 Immunex Corporation Proteines du type proteine adaptatrice myd88
WO2002008285A2 (fr) * 2000-06-22 2002-01-31 Amgen, Inc. Molecules il-17 et leurs utilisations
AU2002226033A1 (en) 2000-12-07 2002-06-18 Zymogenetics Inc. Adipocyte complement related protein zacrp3x2
WO2002090520A2 (fr) 2001-05-09 2002-11-14 Yale University Proteine adaptatrice receptrice de la toll/interleukine-1 (tirap)
AU2015338958A1 (en) * 2014-10-31 2017-05-11 Baylor College Of Medicine Survivin specific T-cell receptor targeting tumor but not T cells
CN106047818A (zh) * 2016-08-05 2016-10-26 武汉赛云博生物科技有限公司 癌胚抗原特异性tcr基因修饰的t细胞及其抑癌用途

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1998027114A2 (fr) * 1996-12-17 1998-06-25 Schering Corporation Antigenes de surface mammaliens et reactifs associes

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1998027114A2 (fr) * 1996-12-17 1998-06-25 Schering Corporation Antigenes de surface mammaliens et reactifs associes

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
DATABASE EMBL 31 December 1998 (1998-12-31), STRAUSBERG R.: "EST; H. sapiens cDNA clone IMAGE:2009429 similar to leukocyte surface protein", XP002143583 *
RUEGG C.L. ET AL.: "V7, a novel leukocyte surface protein that participates in T cell activation. II. Molecular cloning and characterization of the V7 gene.", J. IMMUNOL., vol. 154, 1995, pages 4434 - 4443, XP002143613 *

Also Published As

Publication number Publication date
WO2000060080A2 (fr) 2000-10-12
CA2367378A1 (fr) 2000-10-12
JP2002540791A (ja) 2002-12-03
AU4201000A (en) 2000-10-23
EP1165788A2 (fr) 2002-01-02

Similar Documents

Publication Publication Date Title
WO2001012662A3 (fr) Proteines associees a la membrane
WO2000070049A3 (fr) Molecules de signalisation extracellulaires
WO1999061471A3 (fr) Proteines transmembranaires humaines
WO2002046383A3 (fr) Molecules de modification et de maintenance proteiques
WO2000034477A3 (fr) Proteines associees a des neurones
WO2000018922A3 (fr) Proteines humaines associees a des glucides
WO1999058692A3 (fr) Proteines associees a l'apoptose humaine
WO2000012703A3 (fr) Molecules associees au transport de proteines
WO2000026245A3 (fr) Proteines de transport membranaire
WO2000060080A3 (fr) Molecules du systeme immunitaire
WO2000052151A3 (fr) Proteines de secretion humaines
WO2000014251A3 (fr) Transferases humaines
WO2000005374A3 (fr) Molecules associees a une proliferation cellulaire
WO2000044900A3 (fr) Proteines liant des acides nucleiques
WO2000000594A3 (fr) Transferases humaines
WO2001007471A3 (fr) Proteines du cycle et de proliferation cellulaires
WO2000056891A3 (fr) Proteines transmembranaires humaines
WO2001032888A3 (fr) Molecules humaines de la transferase
WO2000020604A3 (fr) Molecules d'oxydoreductase
WO1999041373A3 (fr) Molecules humaines associees au transport
WO1999057270A3 (fr) Molecules de recepteur humain
WO1999038981A3 (fr) Molecules de proteine kinase humaines
WO2000065054A3 (fr) Proteines humaines associees aux membranes
WO2000077040A3 (fr) Molecules de signalisation intracellulaires
WO1999049037A3 (fr) Molecules apparentees a la proteine-phosphatase

Legal Events

Date Code Title Description
AK Designated states

Kind code of ref document: A2

Designated state(s): AE AL AM AT AU AZ BA BB BG BR BY CA CH CN CU CZ DE DK EE ES FI GB GD GE GH GM HR HU ID IL IN IS JP KE KG KP KR KZ LC LK LR LS LT LU LV MD MG MK MN MW MX NO NZ PL PT RO RU SD SE SG SI SK SL TJ TM TR TT UA UG US US UZ VN YU ZA ZW

AL Designated countries for regional patents

Kind code of ref document: A2

Designated state(s): GH GM KE LS MW SD SL SZ TZ UG ZW AM AZ BY KG KZ MD RU TJ TM AT BE CH CY DE DK ES FI FR GB GR IE IT LU MC NL PT SE BF BJ CF CG CI CM GA GN GW ML MR NE SN TD TG

121 Ep: the epo has been informed by wipo that ep was designated in this application
AK Designated states

Kind code of ref document: A3

Designated state(s): AE AL AM AT AU AZ BA BB BG BR BY CA CH CN CU CZ DE DK EE ES FI GB GD GE GH GM HR HU ID IL IN IS JP KE KG KP KR KZ LC LK LR LS LT LU LV MD MG MK MN MW MX NO NZ PL PT RO RU SD SE SG SI SK SL TJ TM TR TT UA UG US US UZ VN YU ZA ZW

AL Designated countries for regional patents

Kind code of ref document: A3

Designated state(s): GH GM KE LS MW SD SL SZ TZ UG ZW AM AZ BY KG KZ MD RU TJ TM AT BE CH CY DE DK ES FI FR GB GR IE IT LU MC NL PT SE BF BJ CF CG CI CM GA GN GW ML MR NE SN TD TG

DFPE Request for preliminary examination filed prior to expiration of 19th month from priority date (pct application filed before 20040101)
WWE Wipo information: entry into national phase

Ref document number: 2000921733

Country of ref document: EP

ENP Entry into the national phase

Ref country code: JP

Ref document number: 2000 609571

Kind code of ref document: A

Format of ref document f/p: F

ENP Entry into the national phase

Ref document number: 2367378

Country of ref document: CA

Ref country code: CA

Ref document number: 2367378

Kind code of ref document: A

Format of ref document f/p: F

WWP Wipo information: published in national office

Ref document number: 2000921733

Country of ref document: EP

REG Reference to national code

Ref country code: DE

Ref legal event code: 8642

WWW Wipo information: withdrawn in national office

Ref document number: 2000921733

Country of ref document: EP