WO2000051634A1 - Preparations de vaccins contenant des acides gras comme composants - Google Patents
Preparations de vaccins contenant des acides gras comme composants Download PDFInfo
- Publication number
- WO2000051634A1 WO2000051634A1 PCT/JP2000/001289 JP0001289W WO0051634A1 WO 2000051634 A1 WO2000051634 A1 WO 2000051634A1 JP 0001289 W JP0001289 W JP 0001289W WO 0051634 A1 WO0051634 A1 WO 0051634A1
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- vaccine
- adjuvant
- trihydroxy
- fatty acid
- virus
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
- C07C69/66—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety
- C07C69/73—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety of unsaturated acids
- C07C69/732—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety of unsaturated acids of unsaturated hydroxy carboxylic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
- A61K31/201—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids having one or two double bonds, e.g. oleic, linoleic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
- A61P33/06—Antimalarials
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/10—Anthelmintics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/10—Anthelmintics
- A61P33/12—Schistosomicides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
- C07C59/40—Unsaturated compounds
- C07C59/42—Unsaturated compounds containing hydroxy or O-metal groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
- C07C69/007—Esters of unsaturated alcohols having the esterified hydroxy group bound to an acyclic carbon atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Virology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Molecular Biology (AREA)
- Immunology (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Pulmonology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biotechnology (AREA)
- Emergency Medicine (AREA)
- AIDS & HIV (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicinal Preparation (AREA)
Description
Claims
Priority Applications (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP00906681A EP1195162B1 (en) | 1999-03-03 | 2000-03-03 | Vaccine preparation containing fatty acid as a constituent |
AU28280/00A AU781316B2 (en) | 1999-03-03 | 2000-03-03 | Vaccine preparation containing fatty acid as a constituent |
JP2000602300A JP4551001B2 (ja) | 1999-03-03 | 2000-03-03 | 脂肪酸を構成成分とするワクチン製剤 |
DE60039113T DE60039113D1 (de) | 1999-03-03 | 2000-03-03 | Impfstoff-präparation die eine fettsäure als inhaltstoff enthält |
CA2365392A CA2365392C (en) | 1999-03-03 | 2000-03-03 | Vaccine preparation containing fatty acid as a constituent |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP11/55732 | 1999-03-03 | ||
JP5573299 | 1999-03-03 |
Publications (1)
Publication Number | Publication Date |
---|---|
WO2000051634A1 true WO2000051634A1 (fr) | 2000-09-08 |
Family
ID=13007040
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/JP2000/001289 WO2000051634A1 (fr) | 1999-03-03 | 2000-03-03 | Preparations de vaccins contenant des acides gras comme composants |
Country Status (6)
Country | Link |
---|---|
EP (1) | EP1195162B1 (ja) |
JP (1) | JP4551001B2 (ja) |
AU (1) | AU781316B2 (ja) |
CA (1) | CA2365392C (ja) |
DE (1) | DE60039113D1 (ja) |
WO (1) | WO2000051634A1 (ja) |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2002017961A1 (fr) * | 2000-08-31 | 2002-03-07 | The Kitasato Institute | Preparation d'un vaccin renfermant un acide gras comme compose |
WO2016170959A1 (ja) * | 2015-04-22 | 2016-10-27 | 株式会社山田養蜂場本社 | 粘膜免疫賦活剤 |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
TWI350174B (en) * | 2003-03-12 | 2011-10-11 | Wyeth Corp | Adjuvanted bovine vaccines |
CN111743888B (zh) * | 2020-06-16 | 2021-10-22 | 广州医科大学附属第一医院 | (2z,4e)-2,4-癸二烯酸在制备用于治疗流感病毒引起的炎症的药物方面的应用 |
Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH059130A (ja) * | 1990-09-21 | 1993-01-19 | Takeda Chem Ind Ltd | イムノグロブリン含有ワクチン製剤 |
JPH07173069A (ja) * | 1993-12-17 | 1995-07-11 | Tsumura & Co | アジュバント作用剤 |
WO1996006627A1 (en) * | 1994-08-26 | 1996-03-07 | The Administrators Of The Tulane Educational Fund | Mutant enterotoxin effective as a non-toxic oral adjuvant |
WO1996032964A1 (fr) * | 1995-04-20 | 1996-10-24 | Societe D'exploitation De Produits Pour Les Industries Chimiques-Seppic | Composition therapeutique comprenant un antigene ou un generateur in vivo d'un compose comprenant une sequence d'acides amines |
-
2000
- 2000-03-03 EP EP00906681A patent/EP1195162B1/en not_active Expired - Lifetime
- 2000-03-03 JP JP2000602300A patent/JP4551001B2/ja not_active Expired - Fee Related
- 2000-03-03 WO PCT/JP2000/001289 patent/WO2000051634A1/ja active IP Right Grant
- 2000-03-03 AU AU28280/00A patent/AU781316B2/en not_active Ceased
- 2000-03-03 DE DE60039113T patent/DE60039113D1/de not_active Expired - Lifetime
- 2000-03-03 CA CA2365392A patent/CA2365392C/en not_active Expired - Fee Related
Patent Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH059130A (ja) * | 1990-09-21 | 1993-01-19 | Takeda Chem Ind Ltd | イムノグロブリン含有ワクチン製剤 |
JPH07173069A (ja) * | 1993-12-17 | 1995-07-11 | Tsumura & Co | アジュバント作用剤 |
WO1996006627A1 (en) * | 1994-08-26 | 1996-03-07 | The Administrators Of The Tulane Educational Fund | Mutant enterotoxin effective as a non-toxic oral adjuvant |
WO1996032964A1 (fr) * | 1995-04-20 | 1996-10-24 | Societe D'exploitation De Produits Pour Les Industries Chimiques-Seppic | Composition therapeutique comprenant un antigene ou un generateur in vivo d'un compose comprenant une sequence d'acides amines |
Non-Patent Citations (3)
Title |
---|
MARUNO, MASAO: "Research for active principles of Pinelliae Tuber and new preparation of crude drug.", JOURNAL OF TRADITIONAL MEDICINES, vol. 14, 1997, pages 81 - 88, XP002928713 * |
See also references of EP1195162A4 * |
YAMADA, HARUKI ET. AL.: "In vivo Antiinfluenza Virus Activity of Kampo Medicine Sho-Seiryu-To Through Mucosal immune System.", METH. FIND. EXP. CLIN. PHARMACOL., vol. 20, no. 3, 1998, pages 185 - 192, XP002928712 * |
Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2002017961A1 (fr) * | 2000-08-31 | 2002-03-07 | The Kitasato Institute | Preparation d'un vaccin renfermant un acide gras comme compose |
US7560484B2 (en) | 2000-08-31 | 2009-07-14 | The Kitasato Institute | Vaccine preparation containing fatty acid as a constituent |
WO2016170959A1 (ja) * | 2015-04-22 | 2016-10-27 | 株式会社山田養蜂場本社 | 粘膜免疫賦活剤 |
Also Published As
Publication number | Publication date |
---|---|
AU2828000A (en) | 2000-09-21 |
EP1195162A1 (en) | 2002-04-10 |
AU781316B2 (en) | 2005-05-19 |
CA2365392C (en) | 2010-12-14 |
CA2365392A1 (en) | 2000-09-08 |
EP1195162A4 (en) | 2005-02-23 |
EP1195162B1 (en) | 2008-06-04 |
JP4551001B2 (ja) | 2010-09-22 |
DE60039113D1 (de) | 2008-07-17 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
JP4769481B2 (ja) | ポリ−γ−グルタミン酸含有免疫補強剤組成物 | |
ES2139879T5 (es) | Adyuvante de la mucosa no toxico. | |
JP4817625B2 (ja) | 粘膜免疫誘導アジュバントを含む新規ワクチン | |
TW201014601A (en) | Novel adjuvant compositions | |
ES2446984T3 (es) | Vacuna contra Escherichia coli enterohemorrágica | |
US20100255033A1 (en) | Non-toxic double mutant forms of pertussis toxin as adjuvants | |
KR100333113B1 (ko) | 헬리코박터피롤리관련위십이지장질환의치료방법 | |
Yasui et al. | Augmentation of anti-influenza virus hemagglutinin antibody production by Peyer's patch cells with Bifidobacterium breve YIT4064. | |
JP4638880B2 (ja) | アルキルホスファチジルコリン配合ワクチン組成物 | |
US7560484B2 (en) | Vaccine preparation containing fatty acid as a constituent | |
JP4551001B2 (ja) | 脂肪酸を構成成分とするワクチン製剤 | |
Gross et al. | Vaccine immune response and side effects with the use of acetaminophen with influenza vaccine | |
Zhang et al. | Immunopotentiating effect of Inonotus obliquus fermentation products administered at vaccination in chickens | |
KR100649286B1 (ko) | 감독화톡신을 포함하는 백신제제 | |
AU764052B2 (en) | Saponin-containing vaccine preparation | |
WO2011005587A1 (en) | Vaccine compositions and methods of use to protect against infectious disease | |
RU2727258C1 (ru) | Способ повышения иммуногенности вакционного штамма чумного микроба | |
MXPA05003413A (es) | Uso del peptido gk-1 para potencial la respuesta inmunologica generada por la vacuna de influenza. | |
WO2004004764A1 (ja) | 抗ホワイトスポット病組成物 | |
Lina | Efficiency Evaluation of 5BT, a Genetically Recombinant Multi-epitope-protein, for Its Application as a Subunit Vaccine against Foot and Mouth Disease | |
AU726542B2 (en) | Vaccines | |
BEES | LIPOSOMES WITH ENHANCED CIRCULATION TIME | |
WO2006019183A1 (ja) | 粘膜免疫、その感作剤を用いる粘膜ワクチン及び予防接種システム |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
AK | Designated states |
Kind code of ref document: A1 Designated state(s): AE AL AM AT AU AZ BA BB BG BR BY CA CH CN CR CU CZ DE DK DM EE ES FI GB GD GE GH GM HR HU ID IL IN IS JP KE KG KR KZ LC LK LR LS LT LU LV MA MD MG MK MN MW MX NO NZ PL PT RO RU SD SE SG SI SK SL TJ TM TR TT TZ UA UG US UZ VN YU ZA ZW |
|
AL | Designated countries for regional patents |
Kind code of ref document: A1 Designated state(s): GH GM KE LS MW SD SL SZ TZ UG ZW AM AZ BY KG KZ MD RU TJ TM AT BE CH CY DE DK ES FI FR GB GR IE IT LU MC NL PT SE BF BJ CF CG CI CM GA GN GW ML MR NE SN TD TG |
|
121 | Ep: the epo has been informed by wipo that ep was designated in this application | ||
DFPE | Request for preliminary examination filed prior to expiration of 19th month from priority date (pct application filed before 20040101) | ||
ENP | Entry into the national phase |
Ref country code: JP Ref document number: 2000 602300 Kind code of ref document: A Format of ref document f/p: F |
|
ENP | Entry into the national phase |
Ref document number: 2365392 Country of ref document: CA Ref country code: CA Ref document number: 2365392 Kind code of ref document: A Format of ref document f/p: F |
|
WWE | Wipo information: entry into national phase |
Ref document number: 28280/00 Country of ref document: AU |
|
WWE | Wipo information: entry into national phase |
Ref document number: 2000906681 Country of ref document: EP |
|
REG | Reference to national code |
Ref country code: DE Ref legal event code: 8642 |
|
WWP | Wipo information: published in national office |
Ref document number: 2000906681 Country of ref document: EP |
|
WWG | Wipo information: grant in national office |
Ref document number: 28280/00 Country of ref document: AU |
|
WWG | Wipo information: grant in national office |
Ref document number: 2000906681 Country of ref document: EP |