WO2000050433A3 - Staphylococcus aureus q13 polynucleotides, polypeptides and methods of use - Google Patents

Staphylococcus aureus q13 polynucleotides, polypeptides and methods of use Download PDF

Info

Publication number
WO2000050433A3
WO2000050433A3 PCT/US2000/004235 US0004235W WO0050433A3 WO 2000050433 A3 WO2000050433 A3 WO 2000050433A3 US 0004235 W US0004235 W US 0004235W WO 0050433 A3 WO0050433 A3 WO 0050433A3
Authority
WO
WIPO (PCT)
Prior art keywords
polypeptides
methods
polynucleotides
staphylococcus aureus
utilizing
Prior art date
Application number
PCT/US2000/004235
Other languages
French (fr)
Other versions
WO2000050433A2 (en
Inventor
Martin J Hibbs
William A Neville
Klaus Schneider
Daniel R Gentry
Original Assignee
Smithkline Beecham Corp
Smithkline Beecham Plc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smithkline Beecham Corp, Smithkline Beecham Plc filed Critical Smithkline Beecham Corp
Publication of WO2000050433A2 publication Critical patent/WO2000050433A2/en
Publication of WO2000050433A3 publication Critical patent/WO2000050433A3/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/305—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Micrococcaceae (F)
    • C07K14/31—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Micrococcaceae (F) from Staphylococcus (G)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Oncology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Communicable Diseases (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)

Abstract

The invention provides Q13 polypeptides and polynucleotides encoding Q13 polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing Q13 polypeptides to screen for antibacterial compounds.
PCT/US2000/004235 1999-02-26 2000-02-18 Staphylococcus aureus q13 polynucleotides, polypeptides and methods of use WO2000050433A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US25901599A 1999-02-26 1999-02-26
US09/259,015 1999-02-26

Publications (2)

Publication Number Publication Date
WO2000050433A2 WO2000050433A2 (en) 2000-08-31
WO2000050433A3 true WO2000050433A3 (en) 2001-01-04

Family

ID=22983141

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2000/004235 WO2000050433A2 (en) 1999-02-26 2000-02-18 Staphylococcus aureus q13 polynucleotides, polypeptides and methods of use

Country Status (1)

Country Link
WO (1) WO2000050433A2 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2010062814A1 (en) 2008-11-26 2010-06-03 Merck Sharp & Dohme Corp. Polypeptides for inducing a protective immune response against staphylococcus aureus

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0786519A2 (en) * 1996-01-05 1997-07-30 Human Genome Sciences, Inc. Staphylococcus aureus polynucleotides and sequences
US6037123A (en) * 1995-09-15 2000-03-14 Microcide Pharmaceuticals, Inc. Methods of screening for compounds active on Staphylococcus aureus target genes

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6037123A (en) * 1995-09-15 2000-03-14 Microcide Pharmaceuticals, Inc. Methods of screening for compounds active on Staphylococcus aureus target genes
EP0786519A2 (en) * 1996-01-05 1997-07-30 Human Genome Sciences, Inc. Staphylococcus aureus polynucleotides and sequences

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
KUNST ET AL.: "The complete genome sequence of the gram-positive bacterium B. subtilis", NATURE,, vol. 390, no. 6657, 20 November 1997 (1997-11-20), pages 249 - 256, XP002931025 *
WILSON ET AL.: "A non-isotopic DNA hybridisation assay for the identification of staphyloccus aureus isolated from foods. Isolated genomic DNA probe from S. aureus,", INT'L J. OF FOOD MICRO,, vol. 22, 1994, pages 43 - 54, XP002931026 *

Also Published As

Publication number Publication date
WO2000050433A2 (en) 2000-08-31

Similar Documents

Publication Publication Date Title
EP0841394A3 (en) Staphylococcus aureus polynucleotides, polypeptides and their uses
EP0892064A3 (en) Recombinant secA2 polypeptide from Staphylococcus aureus and uses thereof
EP0899334A3 (en) FtsZ polypeptides from Streptococcus pneumoniae
WO2000050433A3 (en) Staphylococcus aureus q13 polynucleotides, polypeptides and methods of use
EP0916730A3 (en) FabH from Staphylococcus aureus
WO2000044778A8 (en) mvk
EP0899335A3 (en) MurB gene from Staphylococcus aureus
WO2000061787A3 (en) gyrA
EP0889129A3 (en) GidA1 polypeptides from Staphylococcus aureus
EP0892055A3 (en) GidB polypeptides from Staphylococcus aureus
EP0889123A3 (en) MurC gene of Staphylococcus aureus coding for UDP-N-acetylmuramate:L-alanine Ligase
EP0881297A3 (en) Histidine kinase
EP0890644A3 (en) MurA gene from Staphylococcus aureus encoding DP-N-Acetylglucosamine enolpyruvyl transferase
EP0913481A3 (en) Staphylococcus aureus member of the DEAD-type ATP-dependent RNA helicases (dbpB)
WO1999058684A3 (en) Compounds from moraxella catarrhalis
EP0909820A3 (en) Histidine kinase from Staphylococcus pneumoniae
EP0889131A3 (en) Staphylococcus aureus gidA2 polynucleotides and polypeptides
EP0905247A3 (en) MurF polynucleotides and polypeptides from Staphylococcus
EP0857787A3 (en) Histidine kinase from Staphylococcus aureaus
WO2000065026A3 (en) YycG
WO2000043491A3 (en) yhxB
EP0889128A3 (en) midA1 polypeptides from Streptococcus pneumoniae
WO1999061453A3 (en) priA
EP0906955A3 (en) FtsY
EP0899337A3 (en) FtsY polynucleotides and polypeptides of Stapyloccoccus aureus belonging to the signal recognition protein family

Legal Events

Date Code Title Description
AK Designated states

Kind code of ref document: A2

Designated state(s): JP

AL Designated countries for regional patents

Kind code of ref document: A2

Designated state(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LU MC NL PT SE

121 Ep: the epo has been informed by wipo that ep was designated in this application
AK Designated states

Kind code of ref document: A3

Designated state(s): JP

AL Designated countries for regional patents

Kind code of ref document: A3

Designated state(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LU MC NL PT SE

DFPE Request for preliminary examination filed prior to expiration of 19th month from priority date (pct application filed before 20040101)
122 Ep: pct application non-entry in european phase