WO2000048617A3 - Connective tissue softening - Google Patents
Connective tissue softening Download PDFInfo
- Publication number
- WO2000048617A3 WO2000048617A3 PCT/GB2000/000474 GB0000474W WO0048617A3 WO 2000048617 A3 WO2000048617 A3 WO 2000048617A3 GB 0000474 W GB0000474 W GB 0000474W WO 0048617 A3 WO0048617 A3 WO 0048617A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- connective tissue
- tissue softening
- tendon
- softening
- connective
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
- A61K31/404—Indoles, e.g. pindolol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/55—Protease inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/04—Drugs for skeletal disorders for non-specific disorders of the connective tissue
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Abstract
Priority Applications (9)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DK00903808T DK1152757T3 (en) | 1999-02-18 | 2000-02-14 | MMP inhibitors in connective tissue softness |
US09/913,713 US6455569B1 (en) | 1999-02-18 | 2000-02-14 | Connective tissue softening |
DE60021350T DE60021350T2 (en) | 1999-02-18 | 2000-02-14 | MMP-HEMMER AT BINDING WEB SUBSTANCE |
JP2000599407A JP2002537268A (en) | 1999-02-18 | 2000-02-14 | Softening of connective tissue |
AT00903808T ATE299703T1 (en) | 1999-02-18 | 2000-02-14 | MMP INHIBITORS FOR CONNECTIVE TISSUE SOFTENING |
AU25571/00A AU772470B2 (en) | 1999-02-18 | 2000-02-14 | Connective tissue softening |
CA2362279A CA2362279C (en) | 1999-02-18 | 2000-02-14 | Connective tissue softening |
EP00903808A EP1152757B1 (en) | 1999-02-18 | 2000-02-14 | Mmp inhibitors in connective tissue softening |
HK01108013A HK1037960A1 (en) | 1999-02-18 | 2001-11-14 | Mmp inhibitors in connective tissue softening. |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB9903598.2 | 1999-02-18 | ||
GBGB9903598.2A GB9903598D0 (en) | 1999-02-18 | 1999-02-18 | Connective tissue healing |
Publications (2)
Publication Number | Publication Date |
---|---|
WO2000048617A2 WO2000048617A2 (en) | 2000-08-24 |
WO2000048617A3 true WO2000048617A3 (en) | 2001-02-08 |
Family
ID=10847938
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/GB2000/000474 WO2000048617A2 (en) | 1999-02-18 | 2000-02-14 | Connective tissue softening |
Country Status (13)
Country | Link |
---|---|
US (1) | US6455569B1 (en) |
EP (1) | EP1152757B1 (en) |
JP (1) | JP2002537268A (en) |
AT (1) | ATE299703T1 (en) |
AU (1) | AU772470B2 (en) |
CA (1) | CA2362279C (en) |
DE (1) | DE60021350T2 (en) |
DK (1) | DK1152757T3 (en) |
ES (1) | ES2244410T3 (en) |
GB (1) | GB9903598D0 (en) |
HK (1) | HK1037960A1 (en) |
PT (1) | PT1152757E (en) |
WO (1) | WO2000048617A2 (en) |
Families Citing this family (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6436629B1 (en) * | 2000-10-27 | 2002-08-20 | The Regents Of The University Of California | Modulating angiogenesis |
DE60331367D1 (en) | 2002-12-30 | 2010-04-01 | Angiotech Int Ag | ACTIVE COMPOSITION OF FAST GELING POLYMERIC COMPOSITION |
US20070259030A1 (en) * | 2006-05-05 | 2007-11-08 | Drapeau Susan J | Methods, systems and reagents for tendon and ligament therapy |
RU2542471C2 (en) | 2006-11-15 | 2015-02-20 | Коуда Терапьютикс, Инк. | Improved methods and compositions for wound healing |
US8323642B2 (en) * | 2006-12-13 | 2012-12-04 | Depuy Mitek, Inc. | Tissue fusion method using collagenase for repair of soft tissue |
JP2011507599A (en) * | 2007-12-21 | 2011-03-10 | コーダ セラピューティクス, インコーポレイテッド | Improved medical device |
CA2710388A1 (en) * | 2007-12-21 | 2009-07-09 | Coda Therapeutics, Inc. | Use of anti-connexin polynucleotides for the treatment of abnormal or excessive scars |
CA2710375A1 (en) * | 2007-12-21 | 2009-07-09 | Coda Therapeutics, Inc. | Treatment of orthopedic conditions |
EA201790434A1 (en) | 2014-08-22 | 2017-07-31 | Окленд Юнисервисиз Лимитед | CHANNEL MODULATORS |
WO2022128057A1 (en) | 2020-12-14 | 2022-06-23 | Symrise Ag | Medicament for prevention and treatment of collagen degradation in human connecting tissue |
Citations (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5240958A (en) * | 1988-11-23 | 1993-08-31 | British Bio-Technology Limited | Hydroxamic acid based collagenase inhibitors |
EP0574758A1 (en) * | 1992-06-11 | 1993-12-22 | F. Hoffmann-La Roche Ag | Hydroxamic acid derivatives as collagenase inhibitors |
US5310759A (en) * | 1992-08-12 | 1994-05-10 | Bockman Richard S | Methods of protecting and preserving connective and support tissues |
WO1995024921A1 (en) * | 1994-03-16 | 1995-09-21 | Institute Of Ophthalmology | A medical use of matrix metalloproteinase inhibitors for inhibiting tissue contraction |
DE19542189A1 (en) * | 1995-11-13 | 1997-05-15 | Hoechst Ag | New cyclic alpha-imino:hydroxamic acid derivatives |
WO1999003979A1 (en) * | 1997-07-17 | 1999-01-28 | Smith & Nephew Plc | Methods for the preparation of artificial cellular tissue |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5239078A (en) * | 1990-11-21 | 1993-08-24 | Glycomed Incorporated | Matrix metalloprotease inhibitors |
CA2160139A1 (en) * | 1993-04-07 | 1994-10-13 | Richard Edward Galardy | Synthetic matrix metalloprotease inhibitors and uses thereof |
TR199800849T2 (en) * | 1995-11-13 | 1998-07-21 | Hoechst Aktiengesellschaft | Carboxylic acids with cyclic heterocyclic N-substituted alpha-iminohydroxam |
-
1999
- 1999-02-18 GB GBGB9903598.2A patent/GB9903598D0/en not_active Ceased
-
2000
- 2000-02-14 WO PCT/GB2000/000474 patent/WO2000048617A2/en active IP Right Grant
- 2000-02-14 DE DE60021350T patent/DE60021350T2/en not_active Expired - Lifetime
- 2000-02-14 DK DK00903808T patent/DK1152757T3/en active
- 2000-02-14 AT AT00903808T patent/ATE299703T1/en active
- 2000-02-14 AU AU25571/00A patent/AU772470B2/en not_active Ceased
- 2000-02-14 PT PT00903808T patent/PT1152757E/en unknown
- 2000-02-14 JP JP2000599407A patent/JP2002537268A/en active Pending
- 2000-02-14 EP EP00903808A patent/EP1152757B1/en not_active Expired - Lifetime
- 2000-02-14 US US09/913,713 patent/US6455569B1/en not_active Expired - Fee Related
- 2000-02-14 CA CA2362279A patent/CA2362279C/en not_active Expired - Fee Related
- 2000-02-14 ES ES00903808T patent/ES2244410T3/en not_active Expired - Lifetime
-
2001
- 2001-11-14 HK HK01108013A patent/HK1037960A1/en not_active IP Right Cessation
Patent Citations (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5240958A (en) * | 1988-11-23 | 1993-08-31 | British Bio-Technology Limited | Hydroxamic acid based collagenase inhibitors |
EP0574758A1 (en) * | 1992-06-11 | 1993-12-22 | F. Hoffmann-La Roche Ag | Hydroxamic acid derivatives as collagenase inhibitors |
US5310759A (en) * | 1992-08-12 | 1994-05-10 | Bockman Richard S | Methods of protecting and preserving connective and support tissues |
WO1995024921A1 (en) * | 1994-03-16 | 1995-09-21 | Institute Of Ophthalmology | A medical use of matrix metalloproteinase inhibitors for inhibiting tissue contraction |
DE19542189A1 (en) * | 1995-11-13 | 1997-05-15 | Hoechst Ag | New cyclic alpha-imino:hydroxamic acid derivatives |
WO1999003979A1 (en) * | 1997-07-17 | 1999-01-28 | Smith & Nephew Plc | Methods for the preparation of artificial cellular tissue |
Non-Patent Citations (4)
Title |
---|
ARTHRITIS & RHEUMATISM, vol. 41, no. 12, December 1998 (1998-12-01), pages 2143 - 2151, ISSN: 0004-3591 * |
DATABASE BIOSIS [online] BIOSCIENCES INFORMATION SERVICE, PHILADELPHIA, PA, US; December 1998 (1998-12-01), GANU VISHWAS ET AL: "Inhibition of interleukin-1alpha-induced cartilage oligomeric matrix protein degradation in bovine articular cartilage by matrix metalloproteinase inhibitors.", XP002151898, Database accession no. PREV199900079331 * |
DATABASE BIOSIS [online] BIOSCIENCES INFORMATION SERVICE, PHILADELPHIA, PA, US; October 1998 (1998-10-01), KOZACI L D ET AL: "Stromelysin 1, neutrophil collagenase, and collagenase 3 do not play major roles in a model of chondrocyte mediated cartilage breakdown.", XP002151899, Database accession no. PREV199900005122 * |
MOLECULAR PATHOLOGY, vol. 51, no. 5, October 1998 (1998-10-01), pages 282 - 286, ISSN: 1366-8714 * |
Also Published As
Publication number | Publication date |
---|---|
ES2244410T3 (en) | 2005-12-16 |
CA2362279C (en) | 2010-05-25 |
DE60021350D1 (en) | 2005-08-25 |
JP2002537268A (en) | 2002-11-05 |
ATE299703T1 (en) | 2005-08-15 |
AU2557100A (en) | 2000-09-04 |
HK1037960A1 (en) | 2002-03-01 |
WO2000048617A2 (en) | 2000-08-24 |
AU772470B2 (en) | 2004-04-29 |
DE60021350T2 (en) | 2006-04-27 |
PT1152757E (en) | 2005-09-30 |
CA2362279A1 (en) | 2000-08-24 |
EP1152757A2 (en) | 2001-11-14 |
GB9903598D0 (en) | 1999-04-07 |
US6455569B1 (en) | 2002-09-24 |
DK1152757T3 (en) | 2005-10-31 |
EP1152757B1 (en) | 2005-07-20 |
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