WO2000032791A3 - Acyltransferases lecithine:cholesterol d'origine vegetale - Google Patents

Acyltransferases lecithine:cholesterol d'origine vegetale Download PDF

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Publication number
WO2000032791A3
WO2000032791A3 PCT/US1999/028586 US9928586W WO0032791A3 WO 2000032791 A3 WO2000032791 A3 WO 2000032791A3 US 9928586 W US9928586 W US 9928586W WO 0032791 A3 WO0032791 A3 WO 0032791A3
Authority
WO
WIPO (PCT)
Prior art keywords
lecithin
cholesterol
plan
cholesterol acyltransferases
acyltransferases
Prior art date
Application number
PCT/US1999/028586
Other languages
English (en)
Other versions
WO2000032791A2 (fr
Inventor
Rebecca E Cahoon
Anthony J Kinney
Hajime Sakai
Jennie Bih-Jien Shen
Karlene H Butler
James J Saylor
Original Assignee
Du Pont
Rebecca E Cahoon
Anthony J Kinney
Hajime Sakai
Shen Jennie Bih Jien
Karlene H Butler
James J Saylor
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Du Pont, Rebecca E Cahoon, Anthony J Kinney, Hajime Sakai, Shen Jennie Bih Jien, Karlene H Butler, James J Saylor filed Critical Du Pont
Priority to AU21630/00A priority Critical patent/AU2163000A/en
Priority to US09/857,612 priority patent/US6940003B1/en
Publication of WO2000032791A2 publication Critical patent/WO2000032791A2/fr
Publication of WO2000032791A3 publication Critical patent/WO2000032791A3/fr
Priority to US11/073,512 priority patent/US7238863B2/en

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/1025—Acyltransferases (2.3)
    • C12N9/1029—Acyltransferases (2.3) transferring groups other than amino-acyl groups (2.3.1)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
    • C12N15/8242—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits
    • C12N15/8243—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits involving biosynthetic or metabolic pathways, i.e. metabolic engineering, e.g. nicotine, caffeine
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
    • C12N15/8261—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield
    • C12N15/8271—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for stress resistance, e.g. heavy metal resistance
    • C12N15/8273—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for stress resistance, e.g. heavy metal resistance for drought, cold, salt resistance

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Cell Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Nutrition Science (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
  • Enzymes And Modification Thereof (AREA)

Abstract

L'invention concerne un fragment d'acide nucléique isolé codant pour des acyltransférases lecithine:cholestérol d'origine végétale. Elle concerne aussi la construction d'un gène chimère codant pour la totalité ou pour une partie des acyltransférases lecithine:cholestérol d'origine végétale, à orientation sens ou antisens, l'expression du gène chimère causant la production de quantités modifiées des acyltransférases lecithine:cholestérol d'origine végétale dans une cellule hôte transformée.
PCT/US1999/028586 1998-12-03 1999-12-02 Acyltransferases lecithine:cholesterol d'origine vegetale WO2000032791A2 (fr)

Priority Applications (3)

Application Number Priority Date Filing Date Title
AU21630/00A AU2163000A (en) 1998-12-03 1999-12-02 Plan lecithin:cholesterol acyltransferases
US09/857,612 US6940003B1 (en) 1998-12-03 1999-12-02 Plan lecithin: cholesterol acyltransferases
US11/073,512 US7238863B2 (en) 1998-12-03 2005-03-07 Plant lecithin:cholesterol acyltransferases

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US11078298P 1998-12-03 1998-12-03
US60/110,782 1998-12-03

Related Child Applications (1)

Application Number Title Priority Date Filing Date
US11/073,512 Division US7238863B2 (en) 1998-12-03 2005-03-07 Plant lecithin:cholesterol acyltransferases

Publications (2)

Publication Number Publication Date
WO2000032791A2 WO2000032791A2 (fr) 2000-06-08
WO2000032791A3 true WO2000032791A3 (fr) 2000-09-14

Family

ID=22334901

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US1999/028586 WO2000032791A2 (fr) 1998-12-03 1999-12-02 Acyltransferases lecithine:cholesterol d'origine vegetale

Country Status (2)

Country Link
AU (1) AU2163000A (fr)
WO (1) WO2000032791A2 (fr)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE446370T1 (de) * 1999-04-12 2009-11-15 Monsanto Technology Llc Öl, das brassicastanol enthält
WO2001016308A2 (fr) * 1999-08-30 2001-03-08 Monsanto Technology Llc Acyltransferases sterol d'origine vegetale

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1998046767A1 (fr) * 1997-04-11 1998-10-22 Takeda Chemical Industries, Ltd. Proteines presentant une activite de lecithine-cholesterol semblable a acyltransferase, leur preparation et leur utilisation

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1998046767A1 (fr) * 1997-04-11 1998-10-22 Takeda Chemical Industries, Ltd. Proteines presentant une activite de lecithine-cholesterol semblable a acyltransferase, leur preparation et leur utilisation

Non-Patent Citations (5)

* Cited by examiner, † Cited by third party
Title
MURATA Y. ET AL.: "Cloning of rabbit LCAT cDNA: increase in LCAT mRNA abundance in the liver of cholesterol-fed rabbits", JOURNAL OF LIPID RESEARCH, vol. 37, 1996, pages 1616 - 1622, XP000913765 *
SASAKI T. ET AL.: "Rice EST AC D46513", EBI DATABASE, 9 March 1995 (1995-03-09), XP002139389 *
SHINN P. ET AL.: "Genomic Arabidopsis sequence AC AC004557; Q9ZW42", EBI DATABASE, 15 April 1998 (1998-04-15), XP002139390 *
WALBOT V. ET AL.: "Maize EST, AC AW147120", EBI DATABASE, 4 November 1999 (1999-11-04), XP002139392 *
WARDEN C. ET AL.: "Tissue-specific expression, developmental regulation, and chromosomal mapping of the lecithin:cholesterol acyltransferase gene", JOURNAL OF BIOLOGICAL CHEMISTRY, vol. 264, 1989, pages 21573 - 21581, XP002139391 *

Also Published As

Publication number Publication date
AU2163000A (en) 2000-06-19
WO2000032791A2 (fr) 2000-06-08

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