WO2000027450A1 - Pre-filled retractable needle injection device - Google Patents

Pre-filled retractable needle injection device Download PDF

Info

Publication number
WO2000027450A1
WO2000027450A1 PCT/US1999/026208 US9926208W WO0027450A1 WO 2000027450 A1 WO2000027450 A1 WO 2000027450A1 US 9926208 W US9926208 W US 9926208W WO 0027450 A1 WO0027450 A1 WO 0027450A1
Authority
WO
Grant status
Application
Patent type
Prior art keywords
needle
plunger
barrel
housing
medical device
Prior art date
Application number
PCT/US1999/026208
Other languages
French (fr)
Inventor
Thor Halseth
Michael Botich
Original Assignee
Mdc Investment Holdings, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/31Details
    • A61M5/32Needles; Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles
    • A61M5/3205Apparatus for removing or disposing of used needles or syringes, e.g. containers; Means for protection against accidental injuries from used needles
    • A61M5/321Means for protection against accidental injuries by used needles
    • A61M5/322Retractable needles, i.e. disconnected from and withdrawn into the syringe barrel by the piston
    • A61M5/3232Semi-automatic needle retraction, i.e. in which the triggering of the needle retraction requires a deliberate action by the user, e.g. manual release of spring-biased retraction means
    • A61M5/3234Fully automatic, i.e. in which the triggering does not require a deliberate action by the user
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/31Details
    • A61M5/315Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31501Means for blocking or restricting the movement of the rod or piston
    • A61M2005/31508Means for blocking or restricting the movement of the rod or piston provided on the piston-rod
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/31Details
    • A61M5/32Needles; Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles
    • A61M5/3205Apparatus for removing or disposing of used needles or syringes, e.g. containers; Means for protection against accidental injuries from used needles
    • A61M5/321Means for protection against accidental injuries by used needles
    • A61M5/322Retractable needles, i.e. disconnected from and withdrawn into the syringe barrel by the piston
    • A61M5/3221Constructional features thereof, e.g. to improve manipulation or functioning
    • A61M2005/3231Proximal end of needle captured or embedded inside piston head, e.g. by friction or hooks

Abstract

A safety needle-bearing medical device (10) is provided. After use the needle (50) is retracted into the housing (20) of the device to prevent inadvertent contact with the contaminated needle. The invention provides a syringe having a retractable needle. At the end of the injection stroke, the plunger (30) engages a needle retainer that releasably retains the needle. The needle (50) is then released, and a biasing element (60) biases the needle rearwardly. In a preferred embodiment, the needle retainer comprises an adhesive (65) having sufficient strength to retain the needle (50) against the bias of the biasing element (60) prior to actuation of retraction. In addition, the bond of the adhesive (65) is sufficiently fracturable to allow release of the needle upon application of the actuation forced by the plunger (30).

Description

PRE-FILLED RETRACTABLE NEEDLE INJECTION DEVICE

Field of the Invention

The present invention relates to syringes for administering injections of medicinal fluids to patients. More specifically, the invention relates to such devices having a retractable needle feature for rendering the device non-reusable and safely disposable.

Background of the Invention

Various types of medical devices employ a needle for piercing the skin of a patient for diagnostic or therapeutic purposes. One such device is a hypodermic syringe. Handling of such needle-bearing medical devices after the needle is withdrawn from the patient can result in transmission of various pathogens, most notably human immune virus (HIV) , to uninfected medical personnel, due to an inadvertent needle stick. Accordingly, it is desirable to provide a device for injecting medication, wherein the injection needle is retracted into the housing of the device after use.

Description of the Drawings All of the objects of the present invention are more fully set forth hereinafter with reference to the accompanying drawings, wherein:

Fig. la is a side view of a hypodermic syringe having a retractable needle, illustrated prior to use; Fig. lb is a side view of the syringe illustrated in Fig. la, illustrating the device just prior to retraction of the needle;

Fig. lc is a side view of the syringe illustrated in Fig. la, illustrating the device after the needle has been retracted;

Fig. 2a is an enlarged fragmentary view of the syringe illustrated in Fig. la;

Fig. 2b is an enlarged fragmentary view of the syringe illustrated in Fig. lb;

Fig. 2c is an enlarged fragmentary view of the syringe illustrated in Fig. lc;

Fig. 3 is an enlarged view of a needle assembly of the syringe illustrated in Fig. la;

Fig. 4a is a side view of a second embodiment of a hypodermic syringe having a retractable needle, illustrated prior to use;

Fig. 4b is a side view of the syringe illustrated in Fig. 4a, illustrating the device just prior to retraction of the needle;

Fig. 4c is a side view of the syringe illustrated in Fig. 4a, illustrating the device after the needle has been retracted;

Fig. 5a is an enlarged fragmentary view of the syringe illustrated in Fig. 4a;

Fig. 5b is an enlarged fragmentary view of the syringe illustrated in Fig. 4b;

Fig. 5c is an enlarged fragmentary view of the syringe illustrated in Fig. 4c;

Fig. 6a is a side view of a third embodiment of a hypodermic syringe having a retractable needle, illustrated prior to use;

Fig. 6b is a side view of the syringe illustrated in Fig. 6a, illustrating the device just prior to retraction of the needle; and

Fig. 6c is a side view of the syringe illustrated in Fig. βa, illustrating the device after the needle has been retracted.

Detailed Description of the Preferred Embodiments

Referring now to Figs la-3, and to Figs la-lc more specifically, a syringe for injecting medicinal fluid is designated generally 10. The syringe includes a needle assembly 40 mounted on the forward of a barrel 20. A plunger 30 is slidably displaceable within the barrel. Displacing the plunger 30 forwardly in the barrel 20 expels the fluid from the syringe 10 into the patient. At the end of the injection stroke, the plunger engages the needle assembly 40 to actuate retraction of the needle. The needle then automatically retracts so that the contaminated needle is enclosed within the housing. Referring to Fig. la, the barrel 20 is generally cylindrical, having a generally closed forward end and a generally open rearward end for receiving the plunger 30. The forward end of the barrel is a fixed generally rigid wall having an opening for receiving the needle. The forward end of the barrel further includes an internally threaded Luer socket 22.

The plunger is slidably displaceable within the barrel. The plunger 30 includes a rubber piston 32 mounted on the forward end of the plunger 30. The piston 32 forms a fluid-tight seal with the interior wall of barrel, so that a fluid cavity 25 is formed within the barrel. The forward end of the barrel forms the forward end of the fluid cavity 25, and the piston forms the rearward end of the fluid cavity. The needle assembly 40 is attached to the forward end of the barrel 20. Referring to Fig. 3, the details of the needle assembly are shown most clearly. The needle assembly 40 includes a spring housing 42, a needle 50, and a compression spring 50 for retracting the needle. The spring housing is generally cylindrical having a threaded rearward end forming a Luer fitting 44. The Luer fitting 44 cooperates with the Luer socket 22 on the barrel 20 to connect the needle assembly to the barrel . The sharpened tip of the needle 50 projects from the spring housing 42 for piercing a patient. A needle hub 52 is attached to the rearward end of the needle 50. The spring 60 bears against the needle hub 52 biasing the needle rearwardly. The needle 50 is releasably attached to the needle housing to retain the needle against the rearward bias of the spring 60. As shown m Fig. 2a, in the present instance, the needle is attached to the needle housing by an adhesive 65.

Referring again to Fig. la, the rearward end of the needle projects rearwardly from the spring housing 42 so that when the needle assembly is mounted on the barrel 20 the needle assembly projects into the fluid cavity 25 m the barrel. Specifically, m the present instance, the needle hub 52 project into the fluid cavity. The needle hub 52 includes a plurality of side ports or openings 55 formed in the rearward end of the needle hub. The openings provide a fluid path for air to prevent air from becoming trapped in the forward end of the fluid cavity 25. The needle hub 52 is disposed so that the opening 55 are aligned with the forward end of the fluid cavity 25.

The needle hub 52 further includes a plurality of sealing ribs 54 that form a fluid tight seal between the needle assembly 40 and the barrel. More particularly, as shown in Fig. 2a, the sealing ribs 54 form a fluid-tight seal between the needle hub 52 and the Luer socket 22. In this way, the sealing ribs 54 provide a fluid-tight seal preventing leakage of fluid from the fluid cavity 25 into the spring housing. The needle assembly 40 can be attached to the barrel by either the manufacturer or by the user just prior to use. Preferably, the barrel is pre-filled with a measured dose of medicine. Alternatively, medicine can be drawn into the barrel by drawing the plunger rearwardly within the barrel. Configured m this way, the syringe operates as follows. As shown in Figs, la and 2a, prior to injection, the plunger is disposed in the rearward end of the barrel 20 and medicinal fluid is in the fluid cavity 25. The plunger is driven forward in the barrel to inject fluid from the fluid cavity 25 through the needle and into the patient. When the plunger is displaced into the forward end of the barrel, the plunger engages the rearward end of the needle assembly 40, as shown n Figs. lb and 2b. Specifically, the plunger engages the needle hub 52. Continued forward displacement of the plunger forces the needle forwardly, fracturing the bond between the spring housing and the needle. The spring then propels the needle rearwardly into the barrel so that the sharpened tip of the needle is withdrawn into the syringe, as shown in Figs, lc and 2c.

Since the plunger abuts the needle 50, the spring drives the needle and the plunger rearwardly. Accordingly, the spring force is sufficient to overcome the friction between the piston 32 and the inside wall of the barrel 20. At the same time, the adhesive bond between the spring housing 42 and the needle is sufficient to retain the needle against the rearward bias of the spring, while providing a readily fracturable interface so that the force required to actuate retraction is not significant. In the present instance, the glue bond fractures upon application of approximately 4-6 pounds of force on the plunger. In addition, the spring housing is formed of plastic and the needle is formed of stainless steel, and preferably the adhesive bonds more strongly with plastic than with stainless steel. In this way, the adhesive will fracture at the interface with the needle rather than at the interface with the needle housing. Therefore, the amount of residual adhesive on the needle after being released is minimal so that the residual adhesive is unlikely to interfere with the opening at the forward end of the barrel during retraction. Preferably, the adhesive is a UV light curing adhesive such as LOCTITE brand Series 3001 adhesive. The spring provides approximately H to 3/4 pounds of force to retract the needle and the plunger .

As the spring 60 propels the needle 50 and the plunger 30 rearwardly, the spring expands so that the needle projects into the fluid cavity 25 in the barrel 20. Accordingly, the opening in the forward end of the barrel 20 is sized to permit both the spring 60 and the needle 50 to pass through the opening.

Referring now to Figs. 4a-c and 5a-c, a second embodiment of a syringe designated generally 110 is illustrated. The syringe 110 operates similarly to first embodiment illustrated in Figs la-3 and described above. Accordingly, elements in the second embodiment that are similar to elements m the first embodiment are designated with like reference numerals, with the addition of 100s thereto.

The syringe 110 includes a barrel 120 a plunger 130 and a needle assembly 140 attached to the forward end of the barrel. The forward end of the barrel 120 has a Luer socket 122 for receiving the needle assembly 140. In addition, the forward end of the barrel is generally closed, having a reduced diameter opening sized to receive the rearward end of the needle 150.

As shown in Figs. 4a and 5a, prior to use, the needle assembly 140 retains the needle 150 so that the rearward end of the needle projects into the barrel 120 into a fluid cavity 125 in the barrel 120 formed between the forward end of the plunger 130 and the forward end of the barrel. The needle assembly 140 comprises a spring housing 142 and a compression spring 160. The sharpened tip of the needle projects forwardly from the spring housing 142, and the spring 160 biases the needle 150 rearwardly.

The needle 150 is releasably attached to the spring housing 142 to retain the needle against the bias of the needle. The needle 150 is attached to the spring housing by a retaining disk 145 fixed to the needle. The retaining disk is fixed to the needle by an adhesive similar to the adhesive described above in connection with the first embodiment. The retaining disk is attached to the spring housing by a snap fit. Specifically, a seat for retaining the disk 145 is formed between an annular shoulder and an annular rib formed on the interior wall of the spring housing. The needle assembly 140 includes a Luer fitting for attaching the needle assembly to the Luer socket 122 on the forward end of the barrel 120. When the needle assembly is attached to the barrel 120, the needle projects rearwardly into the barrel. Preferably, a side port is formed in the rearward end of the needle to provide a fluid passage for air to prevent air from becoming trapped m the forward end of the barrel.

Operation of the syringe 110 is similar to operation of the first embodiment. As shown m Fig. 4a, prior to use, the plunger is disposed m the rearward end of the barrel. Driving the plunger forwardly in the barrel injects fluid from the fluid cavity 125 into the patient. As shown m Figs. 4b and 5b, at the end of the injection stroke of the plunger, the plunger engages the needle and drives the needle forwardly breaking the bond between the disk 145 and the needle to release the needle. The spring then propels the needle and the plunger rearwardly. After retraction, the spring remains enclosed within the spring housing so that the opening at the forward end of the barrel can be reduced to allow passage of only the needle.

The syringe may include a plunger lock for preventing re-extension of the needle after the needle is retracted. In other words, the plunger can be locked in the extended position after the needle is retracted. For instance, as shown in Figs. 4a-4c the plunger may include an arm 135 or tab biased outwardly that engages the rearward end of the barrel after retraction to prevent re-extension of the needle. Alternatively, the tip of the needle can be bent, thereby causing the tip to skew off-center after the needle is retracted into the barrel. A similar plunger lock can be incorporated into the first embodiment illustrated in Figs. la-3.

Referring now to Figs. 6a-c a third embodiment of a syringe designated generally 210 is illustrated. In the third embodiment, the plunger 230 engages the needle 250 and draws the needle into the barrel 220 to retract the needle as described further below.

Referring to Fig. 6a, the barrel 220 has a generally closed forward end. The syringe 210 may be configured so that a needle assembly is threadedly connectable with the forward end of the barrel as described above in connection with the first two embodiments. However, in the present instance, the needle 250 is attached to a reduced diameter tip 222 that is integrally formed with the forward end of the barrel 220. Similarly, the first two embodiments may configured so that the needle is attached to a tip integrally formed with the barrel, rather than utilizing a separable needle assembly.

The tip 222 releasably retains the needle, preferably by an adhesive 265 similar to the adhesive described above in connection with the first embodiment. A needle fitting in the form of a barb 252 is connected to the rearward end of the needle so that the needle fitting projects into the fluid cavity 225 m the barrel that is between the piston 232 and the forward end of the barrel 220.

The plunger 230 includes a socket 235 for connectably engaging the needle fitting 252. The piston 232 seals the socket 235 prior to use. In addition, a compression spring 260 is disposed about the plunger 230, between the rearward end of the barrel and the rearward end of the plunger. Prior to use, the spring 260 is in its relaxed or extended state, as shown in Fig. 6a. During use, the user advances the plunger in the barrel 220 to expel medicine from the syringe 210. When the user advances the plunger, the spring compresses, biasing the plunger rearwardly. At the end of the injection stroke, the needle fitting 252 pierces the piston, exposing the socket m the end of the plunger. Upon continued advancement of the plunger, the socket 235 engages the needle fitting 252 so that the needle connects with the plunger. Further advancement of the plunger drives the needle 250 forwardly fracturing the adhesive bond, thereby releasing the needle. When the user releases the plunger the spring 260 propels the plunger 230 and the attached needle 250 rearwardly so that the sharpened tip of the needle is retracted into the barrel.

Claims

Claims
1. A medical device comprising: a. a barrel having a generally closed forward end; b. a plunger slidably disposed within the barrel, the plunger comprising a piston forming a fluid-tight seal with the barrel such that a fluid cavity for receiving medicinal fluid is formed between the forward end of the barrel and the piston; c. a needle having a sharpened tip and being operable between a projecting position m which the sharpened tip projects forwardly from the barrel and a retracted position in which the sharpened tip is retracted into the fluid cavity; d. a needle retainer operable to releasably retain the needle; e. a spring operable to displace the needle and the plunger rearwardly into the retracted position; f. wherein forward displacement of the plunger operates to release the needle so that the biasing element can displace the needle rearwardly .
2. The medical device of claim 1 wherein the needle retainer is an adhesive.
3. The medical device of claim 1 comprising a spring housing, wherein the spring is disposed within the spring housing prior to retraction of the needle, and at least a portion of the spring is disposed in the fluid cavity after retraction of the needle.
4. The medical device of claim 1 comprising a plunger lock engaging the barrel to prevent forward displacement of the plunger after the needle is retracted.
5. The medical device of claim 1 wherein the plunger engages the needle.
6. The medical device of claim 1 wherein the plunger is operable to displace the needle forwardly to release the needle from the needle retainer.
7. The medical device of claim 1 comprising a housing, wherein the needle retainer is disposed within the housing and the housing is separable from the barrel .
8. The medical device of claim 7 comprising a seal between the housing and the needle to prevent leakage from the fluid cavity.
9. A medical device comprising: a hollow housing; a needle having a sharpened tip; a biasing element biasing the needle rearwardly wherein after use of the device the biasing element propels the needle rearwardly so that the sharpened tip is enclosed within the housing.
PCT/US1999/026208 1998-11-06 1999-11-05 Pre-filled retractable needle injection device WO2000027450A1 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
US10742298 true 1998-11-06 1998-11-06
US60/107,422 1998-11-06

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
AU1609500A AU1609500A (en) 1998-11-06 1999-11-05 Pre-filled retractable needle injection device

Publications (1)

Publication Number Publication Date
WO2000027450A1 true true WO2000027450A1 (en) 2000-05-18

Family

ID=22316571

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US1999/026208 WO2000027450A1 (en) 1998-11-06 1999-11-05 Pre-filled retractable needle injection device

Country Status (1)

Country Link
WO (1) WO2000027450A1 (en)

Cited By (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1092442A1 (en) * 1999-10-15 2001-04-18 Becton, Dickinson and Company Method of making a retracting needle syringe
EP1092443A3 (en) * 1999-10-15 2002-04-03 Becton, Dickinson and Company Retracting needle syringe
EP1281410A1 (en) * 2001-08-03 2003-02-05 Sergio Restelli Automatic safety syringe
WO2004035120A3 (en) * 2002-10-18 2004-07-01 Advanced Protective Injection Injection syringe with retractable needle
US6840291B2 (en) 1999-10-15 2005-01-11 Becton Dickinson And Company Attachment for a medical device
US7182734B2 (en) 2001-08-09 2007-02-27 Becton, Dickinson And Company Retracting needle safety device
US7258678B2 (en) 2002-03-14 2007-08-21 Becton, Dickinson And Company Retractable safety needle
US9526846B2 (en) 2009-08-19 2016-12-27 Safety Syringes, Inc. Patient-contact activated needle stick safety device

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4973316A (en) * 1990-01-16 1990-11-27 Dysarz Edward D One handed retractable safety syringe
US5487732A (en) * 1992-05-15 1996-01-30 Safe-T-Limited Syringe with retractable needle
US5792107A (en) * 1909-05-10 1998-08-11 Petrocelli; Pasqualino Disposable safety syringe

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5792107A (en) * 1909-05-10 1998-08-11 Petrocelli; Pasqualino Disposable safety syringe
US4973316A (en) * 1990-01-16 1990-11-27 Dysarz Edward D One handed retractable safety syringe
US5487732A (en) * 1992-05-15 1996-01-30 Safe-T-Limited Syringe with retractable needle

Cited By (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1092442A1 (en) * 1999-10-15 2001-04-18 Becton, Dickinson and Company Method of making a retracting needle syringe
EP1092443A3 (en) * 1999-10-15 2002-04-03 Becton, Dickinson and Company Retracting needle syringe
US6632198B2 (en) 1999-10-15 2003-10-14 Becton Dickinson And Company Retracting needle syringe
US6840291B2 (en) 1999-10-15 2005-01-11 Becton Dickinson And Company Attachment for a medical device
EP1281410A1 (en) * 2001-08-03 2003-02-05 Sergio Restelli Automatic safety syringe
US6712788B2 (en) 2001-08-03 2004-03-30 Nardino Righi Automatic safety syringe
US7182734B2 (en) 2001-08-09 2007-02-27 Becton, Dickinson And Company Retracting needle safety device
US7258678B2 (en) 2002-03-14 2007-08-21 Becton, Dickinson And Company Retractable safety needle
WO2004035120A3 (en) * 2002-10-18 2004-07-01 Advanced Protective Injection Injection syringe with retractable needle
US9526846B2 (en) 2009-08-19 2016-12-27 Safety Syringes, Inc. Patient-contact activated needle stick safety device

Similar Documents

Publication Publication Date Title
US6746429B2 (en) Needle assisted jet injector
US6413237B1 (en) Hypodermic syringe with selectively retractable needle
US4900307A (en) Safety retracting needle for use with syringe
US5098382A (en) Safety module-activator reshielding tool
US4820275A (en) Retractable needle syringe with integral spring
US4932944A (en) Intravenous port injection and connector system
US5062830A (en) Dry disposable nozzle assembly for medical jet injector
US4813936A (en) Retracting hypodermic needle
US6210359B1 (en) Needleless syringe
US5120321A (en) Safety disposable needle
US5788677A (en) Pre-filled retractable needle injection ampoules
US6719730B2 (en) Safety shield system for prefilled syringes
US5167641A (en) Auto-retracting needle injector system
US6558357B1 (en) Hypodermic syringe with selectively retractable needle
US5695475A (en) Syringe apparatus
US5336187A (en) Automatic cover disposable syringe
US5354287A (en) Injector for delivering fluid to internal target tissue
US5358491A (en) Cartridge-needle unit having retractable needle
US4919657A (en) Dental syringe having a medication filled carpule and a retractable needle cannula
US6174304B1 (en) Filling device for a needless injector cartridge
US7670314B2 (en) Injection device for administering a vaccine
US6010486A (en) Retracting needle syringe
US6123688A (en) Pre-filled retractable needle injection devices
US4944723A (en) Universal disposable safety syringe system
US6808507B2 (en) Safety injectors

Legal Events

Date Code Title Description
ENP Entry into the national phase in:

Ref country code: AU

Ref document number: 2000 16095

Kind code of ref document: A

Format of ref document f/p: F

AK Designated states

Kind code of ref document: A1

Designated state(s): AE AL AM AT AU AZ BA BB BG BR BY CA CH CN CR CU CZ DE DK DM EE ES FI GB GD GE GH GM HR HU ID IL IN IS JP KE KG KP KR KZ LC LK LR LS LT LU LV MA MD MG MK MN MW MX NO NZ PL PT RO RU SD SE SG SI SK SL TJ TM TR TT TZ UA UG US UZ VN YU ZA ZW

AL Designated countries for regional patents

Kind code of ref document: A1

Designated state(s): GH GM KE LS MW SD SL SZ TZ UG ZW AM AZ BY KG KZ MD RU TJ TM AT BE CH CY DE DK ES FI FR GB GR IE IT LU MC NL PT SE BF BJ CF CG CI CM GA GN GW ML MR NE SN TD TG

121 Ep: the epo has been informed by wipo that ep was designated in this application
DFPE Request for preliminary examination filed prior to expiration of 19th month from priority date (pct application filed before 20040101)
REG Reference to national code

Ref country code: DE

Ref legal event code: 8642

122 Ep: pct application non-entry in european phase