WO2000019989A3 - Utilisation de derives de catechine comme inhibiteurs de proteinase - Google Patents
Utilisation de derives de catechine comme inhibiteurs de proteinase Download PDFInfo
- Publication number
- WO2000019989A3 WO2000019989A3 PCT/EP1999/007068 EP9907068W WO0019989A3 WO 2000019989 A3 WO2000019989 A3 WO 2000019989A3 EP 9907068 W EP9907068 W EP 9907068W WO 0019989 A3 WO0019989 A3 WO 0019989A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- catechol derivatives
- proteinase inhibitors
- catechol
- derivatives
- matastatic
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
- A61K31/05—Phenols
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/16—Emollients or protectives, e.g. against radiation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Abstract
Priority Applications (11)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
SI9930263T SI1119351T1 (en) | 1998-10-02 | 1999-09-23 | Use of catechol derivatives as proteinase inhibitors |
DK99969932T DK1119351T3 (da) | 1998-10-02 | 1999-09-23 | Anvendelse af katecholderivater som proteinaseinhibitorer |
CA002346019A CA2346019A1 (fr) | 1998-10-02 | 1999-09-23 | Utilisation de derives de catechine comme inhibiteurs de proteinase |
NZ510820A NZ510820A (en) | 1998-10-02 | 1999-09-23 | Use of catechol derivatives as proteinase inhibitors |
AT99969932T ATE238781T1 (de) | 1998-10-02 | 1999-09-23 | Verwendung von katecholderivaten als proteinaseinhibitoren |
US09/806,466 US6509368B1 (en) | 1998-10-02 | 1999-09-23 | Use of catechol derivatives as proteinase inhibitors |
AU59813/99A AU766379B2 (en) | 1998-10-02 | 1999-09-23 | Use of catechol derivatives as proteinase inhibitors |
DE59905355T DE59905355D1 (de) | 1998-10-02 | 1999-09-23 | Verwendung von katecholderivaten als proteinaseinhibitoren |
EP99969932A EP1119351B1 (fr) | 1998-10-02 | 1999-09-23 | Utilisation de derives de catechine comme inhibiteurs de proteinase |
JP2000573350A JP2002526404A (ja) | 1998-10-02 | 1999-09-23 | プロテアーゼ阻害剤としてのカテコール誘導体の使用方法 |
HK02100704.5A HK1039451B (zh) | 1998-10-02 | 2002-01-29 | 包含胰島素敏化劑的藥物組合物 |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE19845372A DE19845372A1 (de) | 1998-10-02 | 1998-10-02 | Verwendung von Katecholderivaten als Proteinaseninhibitoren |
DE19845372.8 | 1998-10-02 |
Publications (2)
Publication Number | Publication Date |
---|---|
WO2000019989A2 WO2000019989A2 (fr) | 2000-04-13 |
WO2000019989A3 true WO2000019989A3 (fr) | 2000-11-09 |
Family
ID=7883162
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/EP1999/007068 WO2000019989A2 (fr) | 1998-10-02 | 1999-09-23 | Utilisation de derives de catechine comme inhibiteurs de proteinase |
Country Status (14)
Country | Link |
---|---|
US (1) | US6509368B1 (fr) |
EP (1) | EP1119351B1 (fr) |
JP (1) | JP2002526404A (fr) |
AT (1) | ATE238781T1 (fr) |
AU (1) | AU766379B2 (fr) |
CA (1) | CA2346019A1 (fr) |
DE (2) | DE19845372A1 (fr) |
DK (1) | DK1119351T3 (fr) |
ES (1) | ES2198992T3 (fr) |
HK (1) | HK1039451B (fr) |
HU (1) | HUP0104162A3 (fr) |
NZ (1) | NZ510820A (fr) |
PT (1) | PT1119351E (fr) |
WO (1) | WO2000019989A2 (fr) |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2003009807A2 (fr) | 2001-07-23 | 2003-02-06 | Galileo Laboratories, Inc. | Composes cytoprotecteurs, procedes et formulations pharmaceutiques et cosmetiques |
Citations (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1982003729A1 (fr) * | 1981-04-08 | 1982-10-28 | Lo Gorton | Electrode pour la regeneration electrochimique de coenzymes, procede de fabrication de cette electrode et son utilisation |
DE3518655A1 (de) * | 1985-05-24 | 1986-11-27 | Grünenthal GmbH, 5190 Stolberg | Neue phenolderivate, diese enthaltende arzneimittel und verfahren zur herstellung dieser verbindungen und arzneimittel |
WO1988001509A1 (fr) * | 1986-08-25 | 1988-03-10 | Chemex Pharmaceuticals, Inc. | Compositions pharmacologiquement actives de butanes catecholiqueset de zinc |
WO1995000129A1 (fr) * | 1993-06-23 | 1995-01-05 | Chemex Pharmaceuticals Inc. | Traitement des maladies a resistance multiple aux anti-cancereux |
WO1996031206A2 (fr) * | 1995-04-07 | 1996-10-10 | Warner-Lambert Company | Flavones et coumarines utilisees en tant qu'agents dans le traitement de l'atherosclerose |
WO1997011692A2 (fr) * | 1995-09-11 | 1997-04-03 | Osteoarthritis Sciences, Inc. | Inhibiteurs de proteine-tyrosine-kinase pour le traitement de l'osteo-arthrite |
JPH11209276A (ja) * | 1998-01-20 | 1999-08-03 | Gifu Prefecture | ガン転移抑制剤及びコラゲナーゼ活性抑制剤 |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU8742198A (en) * | 1997-08-15 | 1999-03-08 | Shire International Licensing B.V. | Use of cholinesterase inhibitor for treating diseases associated with pro teolytic enzyme activity |
-
1998
- 1998-10-02 DE DE19845372A patent/DE19845372A1/de not_active Ceased
-
1999
- 1999-09-23 NZ NZ510820A patent/NZ510820A/en unknown
- 1999-09-23 WO PCT/EP1999/007068 patent/WO2000019989A2/fr active IP Right Grant
- 1999-09-23 US US09/806,466 patent/US6509368B1/en not_active Expired - Fee Related
- 1999-09-23 PT PT99969932T patent/PT1119351E/pt unknown
- 1999-09-23 AT AT99969932T patent/ATE238781T1/de not_active IP Right Cessation
- 1999-09-23 ES ES99969932T patent/ES2198992T3/es not_active Expired - Lifetime
- 1999-09-23 EP EP99969932A patent/EP1119351B1/fr not_active Expired - Lifetime
- 1999-09-23 DE DE59905355T patent/DE59905355D1/de not_active Expired - Fee Related
- 1999-09-23 AU AU59813/99A patent/AU766379B2/en not_active Ceased
- 1999-09-23 JP JP2000573350A patent/JP2002526404A/ja not_active Withdrawn
- 1999-09-23 CA CA002346019A patent/CA2346019A1/fr not_active Abandoned
- 1999-09-23 HU HU0104162A patent/HUP0104162A3/hu unknown
- 1999-09-23 DK DK99969932T patent/DK1119351T3/da active
-
2002
- 2002-01-29 HK HK02100704.5A patent/HK1039451B/zh not_active IP Right Cessation
Patent Citations (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1982003729A1 (fr) * | 1981-04-08 | 1982-10-28 | Lo Gorton | Electrode pour la regeneration electrochimique de coenzymes, procede de fabrication de cette electrode et son utilisation |
DE3518655A1 (de) * | 1985-05-24 | 1986-11-27 | Grünenthal GmbH, 5190 Stolberg | Neue phenolderivate, diese enthaltende arzneimittel und verfahren zur herstellung dieser verbindungen und arzneimittel |
WO1988001509A1 (fr) * | 1986-08-25 | 1988-03-10 | Chemex Pharmaceuticals, Inc. | Compositions pharmacologiquement actives de butanes catecholiqueset de zinc |
WO1995000129A1 (fr) * | 1993-06-23 | 1995-01-05 | Chemex Pharmaceuticals Inc. | Traitement des maladies a resistance multiple aux anti-cancereux |
WO1996031206A2 (fr) * | 1995-04-07 | 1996-10-10 | Warner-Lambert Company | Flavones et coumarines utilisees en tant qu'agents dans le traitement de l'atherosclerose |
WO1997011692A2 (fr) * | 1995-09-11 | 1997-04-03 | Osteoarthritis Sciences, Inc. | Inhibiteurs de proteine-tyrosine-kinase pour le traitement de l'osteo-arthrite |
JPH11209276A (ja) * | 1998-01-20 | 1999-08-03 | Gifu Prefecture | ガン転移抑制剤及びコラゲナーゼ活性抑制剤 |
Non-Patent Citations (2)
Title |
---|
CHEMICAL ABSTRACTS, vol. 131, no. 8, 23 August 1999, Columbus, Ohio, US; abstract no. 97593, SAKAI, YUKIMICHI ET AL: "Magnolol and honokiol from Magnolia bark as cancer metastasis inhibitors and collagenase inhibitors" XP002140193 * |
SCHADE, ULRICH F. ET AL: "Lipoxygenase inhibitors suppress formation of tumor necrosis factor in vitro and in vivo", BIOCHEM. BIOPHYS. RES. COMMUN. (1989), 159(2), 748-54, XP000914523 * |
Also Published As
Publication number | Publication date |
---|---|
AU766379B2 (en) | 2003-10-16 |
DE59905355D1 (de) | 2003-06-05 |
ES2198992T3 (es) | 2004-02-01 |
NZ510820A (en) | 2004-01-30 |
DE19845372A1 (de) | 2000-04-20 |
PT1119351E (pt) | 2003-09-30 |
HUP0104162A2 (hu) | 2002-05-29 |
ATE238781T1 (de) | 2003-05-15 |
HUP0104162A3 (en) | 2002-08-28 |
DK1119351T3 (da) | 2003-08-18 |
EP1119351B1 (fr) | 2003-05-02 |
JP2002526404A (ja) | 2002-08-20 |
US6509368B1 (en) | 2003-01-21 |
HK1039451B (zh) | 2003-08-22 |
EP1119351A2 (fr) | 2001-08-01 |
HK1039451A1 (en) | 2002-04-26 |
AU5981399A (en) | 2000-04-26 |
CA2346019A1 (fr) | 2000-04-13 |
WO2000019989A2 (fr) | 2000-04-13 |
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