WO2000017236A3 - Apoptosis related protein and uses therefor - Google Patents

Apoptosis related protein and uses therefor Download PDF

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Publication number
WO2000017236A3
WO2000017236A3 PCT/US1999/022270 US9922270W WO0017236A3 WO 2000017236 A3 WO2000017236 A3 WO 2000017236A3 US 9922270 W US9922270 W US 9922270W WO 0017236 A3 WO0017236 A3 WO 0017236A3
Authority
WO
WIPO (PCT)
Prior art keywords
arp
nucleic acid
acid molecules
expression vectors
provides isolated
Prior art date
Application number
PCT/US1999/022270
Other languages
French (fr)
Other versions
WO2000017236A8 (en
WO2000017236A2 (en
Inventor
Mehran M Khodadoust
Original Assignee
Millennium Pharm Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Millennium Pharm Inc filed Critical Millennium Pharm Inc
Priority to AU65005/99A priority Critical patent/AU6500599A/en
Publication of WO2000017236A2 publication Critical patent/WO2000017236A2/en
Publication of WO2000017236A3 publication Critical patent/WO2000017236A3/en
Publication of WO2000017236A8 publication Critical patent/WO2000017236A8/en

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4747—Apoptosis related proteins

Abstract

The invention provides isolated nucleic acids molecules, designated ARP nucleic acid molecules, which encode novel ARP family members. The invention also provides antisense nucleic acid molecules, recombinant expression vectors containing ARP nucleic acid molecules, host cells into which the expression vectors have been introduced, and nonhuman transgenic animals in which an ARP gene has been introduced or disrupted. The invention still further provides isolated ARP proteins, fusion proteins, antigenic peptides and anti-ARP antibodies. Diagnostic methods utilizing compositions of the invention are also provided.
PCT/US1999/022270 1998-09-24 1999-09-24 Apoptosis related protein and uses therefor WO2000017236A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU65005/99A AU6500599A (en) 1998-09-24 1999-09-24 Novel apoptosis related proteins and uses therefor

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US16062398A 1998-09-24 1998-09-24
US09/160,623 1998-09-24

Publications (3)

Publication Number Publication Date
WO2000017236A2 WO2000017236A2 (en) 2000-03-30
WO2000017236A3 true WO2000017236A3 (en) 2000-05-25
WO2000017236A8 WO2000017236A8 (en) 2000-07-20

Family

ID=22577668

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US1999/022270 WO2000017236A2 (en) 1998-09-24 1999-09-24 Apoptosis related protein and uses therefor

Country Status (2)

Country Link
AU (1) AU6500599A (en)
WO (1) WO2000017236A2 (en)

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999014327A2 (en) * 1997-09-17 1999-03-25 Genentech, Inc. Genes amplified in tumours, antibodies against the proteins coded thereby, and their use in diagnosis and treatment of cancer

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999014327A2 (en) * 1997-09-17 1999-03-25 Genentech, Inc. Genes amplified in tumours, antibodies against the proteins coded thereby, and their use in diagnosis and treatment of cancer

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
DATABASE EMBL - EMEST29 19 March 1997 (1997-03-19), HILLIER, L. ET AL.: "zr56g02.s1 Soares NhHMPu S1 Homo sapiens cDNA clone 668306 3' similar to TR:G1216486 G1216486 HT protein.", XP002132887 *
DATABASE EMBL - EMEST31 18 April 1997 (1997-04-18), ADAMS, M.D. ET AL.: "EST177865 Jurkat T-cells VI Homo sapiens cDNA 5' end similar to similar to adhesive plaque protein matrix.", XP002132888 *
DATABASE EMBL - EMROD 18 March 1996 (1996-03-18), CHEN, H. ET AL.: "Cricetulus griseus HT protein mRNA, complete cds.", XP002131426 *

Also Published As

Publication number Publication date
WO2000017236A8 (en) 2000-07-20
AU6500599A (en) 2000-04-10
WO2000017236A2 (en) 2000-03-30

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