WO2000009076A3 - Imaging with tc-99m labeled fibrin-alpha-chain peptide - Google Patents

Imaging with tc-99m labeled fibrin-alpha-chain peptide Download PDF

Info

Publication number
WO2000009076A3
WO2000009076A3 PCT/US1999/019011 US9919011W WO0009076A3 WO 2000009076 A3 WO2000009076 A3 WO 2000009076A3 US 9919011 W US9919011 W US 9919011W WO 0009076 A3 WO0009076 A3 WO 0009076A3
Authority
WO
WIPO (PCT)
Prior art keywords
imaging
alpha
chain peptide
compositions
labeled fibrin
Prior art date
Application number
PCT/US1999/019011
Other languages
French (fr)
Other versions
WO2000009076A2 (en
WO2000009076A9 (en
WO2000009076A8 (en
Inventor
Madhukar Mathew L Thakur
Original Assignee
Univ Jefferson
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Jefferson filed Critical Univ Jefferson
Priority to EP99966745A priority Critical patent/EP1105164A4/en
Priority to JP2000564580A priority patent/JP2002522778A/en
Priority to CA002348617A priority patent/CA2348617A1/en
Publication of WO2000009076A2 publication Critical patent/WO2000009076A2/en
Publication of WO2000009076A3 publication Critical patent/WO2000009076A3/en
Publication of WO2000009076A8 publication Critical patent/WO2000009076A8/en
Publication of WO2000009076A9 publication Critical patent/WO2000009076A9/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04Organic compounds
    • A61K51/08Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
    • A61K51/088Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins conjugates with carriers being peptides, polyamino acids or proteins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2123/00Preparations for testing in vivo

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Optics & Photonics (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Investigating Or Analysing Biological Materials (AREA)

Abstract

The present invention involves compositions for radiolabeled agents for imaging mammalian tissue or cells, compositions for radiolabeling agents that bind to mammalian tissue or cells, compositions for radiolabeling agents that bind to fibrin, and methods of using said compositions.
PCT/US1999/019011 1998-08-17 1999-08-17 Imaging with tc-99m labeled fibrin-alpha-chain peptide WO2000009076A2 (en)

Priority Applications (3)

Application Number Priority Date Filing Date Title
EP99966745A EP1105164A4 (en) 1998-08-17 1999-08-17 Imaging with tc-99m labeled fibrin-alpha-chain peptide
JP2000564580A JP2002522778A (en) 1998-08-17 1999-08-17 Imaging using Tc-99m labeled fibrin-α-chain peptide
CA002348617A CA2348617A1 (en) 1998-08-17 1999-08-17 Imaging with tc-99m labeled fibrin-alpha-chain peptide

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US9680398P 1998-08-17 1998-08-17
US60/096,803 1998-08-17

Publications (4)

Publication Number Publication Date
WO2000009076A2 WO2000009076A2 (en) 2000-02-24
WO2000009076A3 true WO2000009076A3 (en) 2000-05-11
WO2000009076A8 WO2000009076A8 (en) 2000-06-29
WO2000009076A9 WO2000009076A9 (en) 2000-08-03

Family

ID=22259142

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US1999/019011 WO2000009076A2 (en) 1998-08-17 1999-08-17 Imaging with tc-99m labeled fibrin-alpha-chain peptide

Country Status (4)

Country Link
EP (1) EP1105164A4 (en)
JP (1) JP2002522778A (en)
CA (1) CA2348617A1 (en)
WO (1) WO2000009076A2 (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108976285B (en) * 2017-05-31 2021-11-30 首都医科大学 Gly-Pro-Arg-Pro-AA modified warfarin, synthesis, activity and application thereof
CN108976284B (en) * 2017-05-31 2021-11-30 首都医科大学 Pentapeptide modified warfarin containing Gly-Pro-Arg-Pro, and synthesis, activity and application thereof

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5968476A (en) * 1992-05-21 1999-10-19 Diatide, Inc. Technetium-99m labeled peptides for thrombus imaging

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5886142A (en) * 1997-05-20 1999-03-23 Thomas Jefferson University Radiolabeled thrombus imaging agents

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5968476A (en) * 1992-05-21 1999-10-19 Diatide, Inc. Technetium-99m labeled peptides for thrombus imaging

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
See also references of EP1105164A4 *

Also Published As

Publication number Publication date
JP2002522778A (en) 2002-07-23
EP1105164A2 (en) 2001-06-13
WO2000009076A2 (en) 2000-02-24
CA2348617A1 (en) 2000-02-24
EP1105164A4 (en) 2004-09-29
WO2000009076A9 (en) 2000-08-03
WO2000009076A8 (en) 2000-06-29

Similar Documents

Publication Publication Date Title
ATE270557T1 (en) HIGHLY CONCENTRATED, LYOPHILIZED AND LIQUID FACTOR-IX FORMULATIONS
AP2000001919A0 (en) Inhibitors of caspases.
UA32577C2 (en) Radiolabeled compound as imaging agents for the diagnosis of arterial and venous thrombi, radiopharmaceuticals and radiopharmaceutical composition and kits for its preparation
AU4981101A (en) Subtilisin variants
HK1033582A1 (en) Antibodies to death receptor 4 (dr4) and uses thereof
DE69732309D1 (en) Primer compositions for the dental sector
ID27600A (en) PIROLO COMPOSITION (2,3d) PYRIMIDINE AND ITS USE
DK0684843T3 (en) Technetium-99m-labeled peptides for diagnostic imaging of inflammation
IL133883A0 (en) Directed cytolysis of target cells, agents and compositions causing cytolysis, and compounds that can be used to produce the agents
BR9806212A (en) Solid pharmaceutical compositions comprising a cyclosporine and an anionic surfactant.
IL130190A0 (en) Methods and compositions for polypeptide engineering
DE69711724T2 (en) Super alloy compositions
WO2001098357A3 (en) Compositions and methods of monoclonal and polyclonal antibodies specific for t cell subpopulations
HK1064585A1 (en) Improved chelator conjugates.
AU7528894A (en) Hydrazino-type n2s2 chelators
BR0011030A (en) Compositions of substantially oil-free cycloporin
ZA986532B (en) Benefit agent compositions comprising mixtures of alpha-hydroxy esters.
ITRM980303A0 (en) COMPOSITION CONTAINING RADIOISOTOPES IMMOBILIZED ON SOLID PARTICLES, PARTICULARLY USEFUL FOR CLINICAL LINEN IN PATHOLOGIES
WO2000033887A3 (en) Methods and formulations for reducing circulating antibodies
WO1998012329A3 (en) Composition and method for enhancing fibrinolysis using antibodies to alpha-2-antiplasmin
BR9910468A (en) Compound, radiometallic complex, preparation for human administration, kit, uses of a compound and a radiometallic complex of the compound, and, fragment of peptide
MX9602557A (en) Proteins from mammalian liver and their use in oncology.
NO953865L (en) Bifunctional chelators and their use in radiopharmaceuticals
WO2000009076A3 (en) Imaging with tc-99m labeled fibrin-alpha-chain peptide
ZA9810371B (en) Th2 cell depletion; compositions; methods.

Legal Events

Date Code Title Description
AK Designated states

Kind code of ref document: A2

Designated state(s): CA JP

AL Designated countries for regional patents

Kind code of ref document: A2

Designated state(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LU MC NL PT SE

121 Ep: the epo has been informed by wipo that ep was designated in this application
AK Designated states

Kind code of ref document: A3

Designated state(s): CA JP US

AL Designated countries for regional patents

Kind code of ref document: A3

Designated state(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LU MC NL PT SE

DFPE Request for preliminary examination filed prior to expiration of 19th month from priority date (pct application filed before 20040101)
AK Designated states

Kind code of ref document: C1

Designated state(s): CA JP US

AL Designated countries for regional patents

Kind code of ref document: C1

Designated state(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LU MC NL PT SE

CFP Corrected version of a pamphlet front page
CR1 Correction of entry in section i

Free format text: PAT. BUL. 08/2000 UNDER (81) ADD "US"; DUE TO LATE TRANSMITTAL BY THE RECEIVING OFFICE

AK Designated states

Kind code of ref document: C2

Designated state(s): CA JP US

AL Designated countries for regional patents

Kind code of ref document: C2

Designated state(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LU MC NL PT SE

COP Corrected version of pamphlet

Free format text: PAGES 2/6-6/6, DRAWINGS, REPLACED BY NEW PAGES 2/6-6/6; DUE TO LATE TRANSMITTAL BY THE RECEIVING OFFICE

WWE Wipo information: entry into national phase

Ref document number: 09763777

Country of ref document: US

WWE Wipo information: entry into national phase

Ref document number: 1999966745

Country of ref document: EP

WWP Wipo information: published in national office

Ref document number: 1999966745

Country of ref document: EP

ENP Entry into the national phase

Ref document number: 2348617

Country of ref document: CA

Ref country code: CA

Ref document number: 2348617

Kind code of ref document: A

Format of ref document f/p: F

WWW Wipo information: withdrawn in national office

Ref document number: 1999966745

Country of ref document: EP